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Full-Text Articles in Biomedical Engineering and Bioengineering

The Role Of Spider Silk In Peripheral Nerve Regeneration, Langston Forbes-Jackson May 2021

The Role Of Spider Silk In Peripheral Nerve Regeneration, Langston Forbes-Jackson

Undergraduate Honors Theses

Spider silk neural guidance channels (NGCs) are highly important innovations in the field of regenerative medicine. This paper will discuss the evidence in the literature that supports their function in regenerative medicine and provide a template for future experiments in the field. While many studies within the past 15 years have demonstrated the validity of spider silk as a scaffold for peripheral nerve regeneration, the molecular mechanics that facilitate regeneration are poorly understood. An emphasis on using silk from orb weaving spiders in particular may have caused researchers to overlook other spiders whose silk could prove to have vastly different …


Technology Aiding In Neonatal Lung Developmental Care, Megan Kirk Dec 2020

Technology Aiding In Neonatal Lung Developmental Care, Megan Kirk

Undergraduate Honors Theses

In this paper, old as well as new technological findings to decrease premature infant mortality are reviewed. This paper discusses fetal development throughout pregnancy from conception to full-term status as well as fetal lung development specifically from conception until full-term status. Several ideas to rapidly develop and mature fetal lungs are discussed such as mothers ingesting artificial surfactant supplements, either independently or coupled with antenatal corticosteroids, as well as intra-amniotic instillation prior to 28 weeks gestational. Drawbacks regarding these two are mentioned as well such as the fetus’s lungs not being mature enough to use the artificial surfactant leading into …