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Full-Text Articles in Biomedical Engineering and Bioengineering
Study Of Porosity Of Gelatin-Alginate Hydrogels To Model Brain Matter For Studying Traumatic Brain Injuries, Apolline Vincent
Study Of Porosity Of Gelatin-Alginate Hydrogels To Model Brain Matter For Studying Traumatic Brain Injuries, Apolline Vincent
Honors Scholar Theses
Traumatic brain injuries (TBIs) affect brain tissue and neuronal signaling, leading to many side effects including death. Research on TBIs is limited by the lack of accurate brain matter models to study the physiological and cellular reaction. Alginate-gelatin hydrogels have been designed and modified to mimic the mechanical properties of the brain to act as an accurate in vitro model. This Honors thesis aims to verify the porous microstructure of gelatin-alginate hydrogels through Scanning Electron Microscopy (SEM) to understand how gelatin and alginate affect the microstructure. I measured the pore sizes of each hydrogel using ImageJ, compared the average pore …
5-Axis Milling For Micro-Machining Of Implantable Flow Sensor, Devin Kot-Thompson
5-Axis Milling For Micro-Machining Of Implantable Flow Sensor, Devin Kot-Thompson
Honors Scholar Theses
5 axis milling is a manufacturing process utilizing CNC technology. It has been widely supported as an effective tool for micro machining throughout multiple industries. In medical manufacturing specifically, there is a large demand for high accuracy at the microscale level as the geometries of medical devices are often highly complex. 5-axis milling offers the means to develop such complex features including curved faces and steep walls. This thesis covers the conversion of a generic 3-axis milling machine into a 5-axis machine. Through testing, the modified device effectively demonstrated its ability to run 5-axis tool paths required for complex designs. …