Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
Articles 1 - 2 of 2
Full-Text Articles in Biomedical Engineering and Bioengineering
Hydrolytic Degradation Study Of Polyphosphazene-Plga Blends, Riley Blumenfield
Hydrolytic Degradation Study Of Polyphosphazene-Plga Blends, Riley Blumenfield
Honors Scholar Theses
The synthesis and in vitro degradation analysis of thin films of poly[(glycineethylglycinato)75(phenylphenoxy)25phosphazene] (PNGEG75PhPh25) and poly[(ethylphenylalanato)25(glycine- ethylglycinato)75phosphazene] (PNEPA25GEG75) blended with poly(lactic-co-glycolic acid) (PLGA) was conducted to determine the blends’ potential for use as scaffolding materials for tissue regeneration applications. The samples were synthesized with glycylglycine ethyl ester (GEG) acting as the primary substituent side group, with cosubstitution by phenylphenol (PhPh) and phenylalanine ethyl ester (EPA) to make the final product [1]. Blends of 25% polyphosphazene, 75% PLGA and 50% polyphosphazene, 50% PLGA were …
Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi Patel
Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi Patel
Honors Scholar Theses
Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.
Objective: Here, we establish a biodegradable, piezoelectric …