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Biomedical Engineering and Bioengineering Commons™
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Articles 1 - 4 of 4
Full-Text Articles in Biomedical Engineering and Bioengineering
Evaluating The Effects Of Muscle Force Production Strategies And Anterior Cruciate Ligament Forces (Strain) On Gait Patterns During Running, Amanda Astrologo
Evaluating The Effects Of Muscle Force Production Strategies And Anterior Cruciate Ligament Forces (Strain) On Gait Patterns During Running, Amanda Astrologo
Honors Scholar Theses
Anterior cruciate ligament (ACL) injuries are among the most common injuries experienced by athletes in the United States. Even after reconstruction surgery individuals have been known to develop complications much later in life, including long-term or permanent alterations to their gait, which may lead to early-onset knee osteoarthritis. This thesis work sought to define these alterations as they pertain specifically to running. Using results and parameters from previous studies, the goal of this study is to compare muscle force production strategies, as they relate to ACL force and strain, of injured and non-injured individuals. These values, muscle forces and ACL …
Mechanical Analysis Of In Vitro Tbi Models, Dana Hamed
Mechanical Analysis Of In Vitro Tbi Models, Dana Hamed
Honors Scholar Theses
This work details the damage done to cells when mechanically hit. The goal was to mechanically analyze in vitro traumatic brain injury (TBI) models. Parts were designed in SolidWorks to create the machine that is used to induce this damage on the cells. A force applicator that uses a 3D-printed micro-hammer to apply force on the brain cells that are being tested was created. Mechanical trauma experimentation was performed with the force applicator, while a high-speed camera recorded the damage, in order to analyze TBI models. Displacement along the scaffold can be tracked from multiple video frames. With these results, …
Distribution And Localization Of Novel Iodine Nanoparticles In The Human Glioma 1242 Growing In The Brains Of Mice, Benjamin Billings
Distribution And Localization Of Novel Iodine Nanoparticles In The Human Glioma 1242 Growing In The Brains Of Mice, Benjamin Billings
Honors Scholar Theses
Observing and designing the in vivo distribution and localization of therapeutic nanoparticles is an essential aspect of developing and understanding novel nanoparticle- based medical treatments. This study investigates novel PEGylated Iodine-based nanoparticles (INPs), an alternate composition to the more widely researched gold nanoparticles (AuNPs), which may help avoid adverse effects associated with AuNPs, such as potential toxicity and skin discoloration, when used in similar applications. Determining the localization of the novel INPs within murine brains containing human glioma U-1242MG cells is critical in assisting the development of radiation dose enhancement therapy for this aggressive cancer. Radiation dose enhancement utilizes the …
Design Of Exercise Equipment For Wheelchair Users: A Case Study In Accessibility Standards, Kate Craddock Rescsanszky
Design Of Exercise Equipment For Wheelchair Users: A Case Study In Accessibility Standards, Kate Craddock Rescsanszky
Honors Scholar Theses
Engineers must consider a number of aspects of every project they work on. Accessibility is one aspect that presents a unique challenge. Rather than being based on absolute material parameters, accessibility is based on how people interact with technology and their built environment. Since 1990, the Americans with Disabilities Act has been the predominant standard in accessibility because of its wide reach and legal mandate. In addition to the ADA, the ASTM and the Institute for Universal Design offer helpful guidelines for designing for accessibility. However, in addition to standards, guidelines, and recommendations, it is important to consult the intended …