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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Electrospinning As A Processing Method For Electroactive Polymers And Composites, Kristin Joy Pawlowski Jan 2004

Electrospinning As A Processing Method For Electroactive Polymers And Composites, Kristin Joy Pawlowski

Theses and Dissertations

Electrospinning was examined for its potential to create functional materials. Three distinct electroactive materials were electrospun into fibers and fiber mats and then characterized with the intent of determining their utility in aerospace and biomedical applications such as micro-air vehicles and the cardiovascular system. Electrospun Graft Elastomers demonstrated potential as actuators, as electromechanical strain testing showed comparable response to the film form of this material. Further improvement of electroactive response was realized with high dielectric inclusions and fiber orientation. Electrospin processing imparted piezoelectric properties to the fibers of poly(vinylidene fluoride). Differential scanning calorimetry and infrared spectroscopy indicated a degree ...


Incorporation Of Tetracycline Hydrochloride Into Electrospun Fibrinogen: A Study Of Mechanical Properties And Time Release, Charles Dudley Anderson Jr. Jan 2004

Incorporation Of Tetracycline Hydrochloride Into Electrospun Fibrinogen: A Study Of Mechanical Properties And Time Release, Charles Dudley Anderson Jr.

Theses and Dissertations

Electrospinning has the capacity to create fibers of natural or synthetic polymers with dimensions that are similar to analogous fibers in native tissue. Mats consisting of fibers of these sub-micron dimensions have shown promise in provoking little immune response and in offering a habitable environment for cell proliferation. Fibrinogen is a natural protein capable of being electrospun and offers the benefit of existing as part of the natural coagulation cascade. Mats of fibrinogen could be utilized as possible hemostatic dressings or as an early scaffold for cell migration for either wound repair or tissue engineering. The addition of antibiotic into ...


Novel Apparatus To Control Electrospinning Fiber Orientation For The Production Of Tissue Engineering Scaffolds, Eugene David Boland Jan 2004

Novel Apparatus To Control Electrospinning Fiber Orientation For The Production Of Tissue Engineering Scaffolds, Eugene David Boland

Theses and Dissertations

The conception of electrospinning can trace its roots back more than 400 years, when it was observed that rubbed amber can deform a droplet of water on a smooth surface, and is based upon simple concepts of charge separation and surface tension. Since that time, considerable effort has been directed at both the cause and utility of this phenomenon. The specific aim of this dissertation project was to develop an automated electrostatic processing apparatus that was capable of controlling the three-dimensional architecture of an electrospun scaffold to further improve its utility in tissue engineering. The efficacy of using this technique ...