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Biomedical Engineering and Bioengineering Commons

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Virginia Commonwealth University

Biomaterials

2012

Articles 1 - 1 of 1

Full-Text Articles in Biomedical Engineering and Bioengineering

Mineralization Potential Of Electrospun Pdo-Hydroxyapatite-Fibrinogen Blended Scaffolds, Isaac Rodriguez, Parthasarathy A. Madurantakam, Jennifer M. Mccool, Scott A. Sell, Hu Yang, Peter C. Moon, Gary L. Bowlin Jan 2012

Mineralization Potential Of Electrospun Pdo-Hydroxyapatite-Fibrinogen Blended Scaffolds, Isaac Rodriguez, Parthasarathy A. Madurantakam, Jennifer M. Mccool, Scott A. Sell, Hu Yang, Peter C. Moon, Gary L. Bowlin

Biomedical Engineering Publications

The current bone autograft procedure for cleft palate repair presents several disadvantages such as limited availability, additional invasive surgery, and donor site morbidity. The present preliminary study evaluates the mineralization potential of electrospun polydioxanone:nano-hydroxyapatite : fibrinogen (PDO : nHA : Fg) blended scaffolds in different simulated body fluids (SBF). Scaffolds were fabricated by blending PDO : nHA : Fg in the following percent by weight ratios: 100 : 0 : 0, 50 : 25 : 25, 50 : 50 : 0, 50 : 0 : 50, 0 : 0 : 100, and 0 : 50 : 50. Samples were immersed …