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Biomedical Engineering and Bioengineering Commons™
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Articles 1 - 3 of 3
Full-Text Articles in Biomedical Engineering and Bioengineering
An In Vivo Study Of The Effects Of Perinatal Caffeine Exposure On Synaptic Efficacy In The Hippocampus Of Freely Moving Adult Rats, Jee Eun Park
Senior Theses and Projects
The synapse from the perforant path to the dentate gyrus has been widely used successfully to demonstrate long-term potentiation, a cellular model underlying learning and memory. Caffeine is one of the most widely consumed psychoactive stimulants in the world. Caffeine consumption increases in alertness, improvements in motor skills, and neurological functions, and these effects have promoted its use throughout history. Although the many short term cognitive benefits of caffeine intake are well understood, the long term effects of caffeine exposure have been widely disputed. Despite this, it is estimated that over 80% of women continue to consume caffeine throughout pregnancy. …
Device For On-Site Production Of Sterile Water For Injection In A Disaster Zone, Chislon M. Richardson, Jeff Hebert
Device For On-Site Production Of Sterile Water For Injection In A Disaster Zone, Chislon M. Richardson, Jeff Hebert
Senior Theses and Projects
This project sought to design and produce a device for the on-site manufacture of sterile water to be subsequently used to produce IV fluid in disaster zone. In order to accomplish this, the water produced must be pure, sterile, non-pyrogenic, and satisfy the United States Pharmacopeia (USP) standard for water for injection (WFI). Ideally, the device should be low powered, low cost, robust yet portable and deliver at least 10 liters per hour. Our design incorporated the purification methods of carbon filtration, reverse osmosis and Ultra-violet treatment. However, due to power and cost constraints our device was neither able to …
Modeling Cardiac Muscle Mechanics, Lorenzo Sewanan
Modeling Cardiac Muscle Mechanics, Lorenzo Sewanan
Senior Theses and Projects
The heart is a complex electro-mechanical system which is intrinsically and intimately linked to physiology and pathology. Cardiac muscle tissue underlies the dynamics of the heart; understanding cardiac muscle tissue allows insight into the working of the heart at a fundamental level. Indeed, models allow a theoretical understanding of systems which necessarily exceeds that of experiment. Here, we describe a novel mathematical model of cardiac muscle mechanics based on functional relations.