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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Structure-Property-Processing Analysis Of Graphene Bioscaffolds For Viability And Differentiation Of C2c12 Cells, Lynn Karriem
Structure-Property-Processing Analysis Of Graphene Bioscaffolds For Viability And Differentiation Of C2c12 Cells, Lynn Karriem
Boise State University Theses and Dissertations
We investigated the structure – property – processing correlation of graphene bioscaffolds produced using three different methods. Bioscaffolds were prepared by chemical vapor deposition (CVD), sublimation of Silicon Carbide (SiC), and printed solvent assisted exfoliated graphene ink. To gain insight into the roughness and topography of graphene, AFM was performed on each bioscaffold. Raman spectroscopy mapping demonstrated differences in the I2D/IG ratio for each scaffold. Young’s modulus was determined by nanoindentation and indicated that epitaxial graphene had the highest average stiffness, followed by CVD, with printed graphene demonstrating the lowest average stiffness. To investigate the biocompatibility of …
Controlling Strain Energy Density In 3d Cellular Collagen Constructs During Complex Loads, Katherine Hollar
Controlling Strain Energy Density In 3d Cellular Collagen Constructs During Complex Loads, Katherine Hollar
Boise State University Theses and Dissertations
Mechanical stimulation applied to damaged soft tissues, such as ligament, can promote tissue remodeling to accelerate healing. To help identify treatments that encourage ligament healing, bioreactors have been designed to subject 3D cellularized constructs to various loading conditions in order to determine the mechanical mechanisms that trigger cell-mediated repair. An innovative approach is to use a bioreactor to apply controlled states of biaxial stress to study the effects of strain energy density and distortion energy on cell activity. Tissue distortion has been linked to changes in the structure and function of ligament, yet the specific impact of distortion energy on …