Biomedical Engineering and Bioengineering Commons^™

Nanomaterials For Photo-Based Diagnostic And Therapeutic Applications, Baohong Yuan, Jyothi Unnikrishna Menon, Khanh Vu, Parth V. Jadeja, Kytai Truong Nguyen, Pranjali P. Tambe

Bioengineering Faculty Publications

Photo-based diagnosis and treatment methods are gaining prominence due to increased spatial imaging resolution, minimally invasive modalities involved as well as localized treatment. Recently, nanoparticles (NPs) have been developed and used in photo-based therapeutic applications. While some nanomaterials have inherent photo-based imaging capabilities, others including polymeric NPs act as nanocarriers to deliver various fluorescent dyes or photosensitizers for photoimaging and therapeutic applications. These applications can vary from Magnetic Resonance Imaging (MRI) and optical imaging to photothermal therapy (PTT) and chemotherapy. Materials commonly used for development of photo-based NPs ranges from metal-based (gold, silver and silica) to polymer- based (chitosan, dextran, …