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Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
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Articles 1 - 30 of 34
Full-Text Articles in Biomedical Engineering and Bioengineering
The Study Of Corrosion On Additive-Manufactured Metals., Braydan Daniels
The Study Of Corrosion On Additive-Manufactured Metals., Braydan Daniels
Electronic Theses and Dissertations
The purpose of this study was to investigate and compare the corrosion mechanisms between wrought and additive-manufactured (3D-printed) copper and stainless steel. The experimental procedure consisted of measuring the open circuit potential, electrochemical impedance spectroscopy, linear sweep voltammetry, Tafel analysis, surface topology, and scanning electron microscopy for each metal within salt water, tap water, sulfuric acid, and synthetic body fluid (excluding copper in synthetic body fluid).
Overall, printed stainless steel was more corrosion-resistant than wrought stainless steel in tap water and synthetic body fluid based on OCP, LSV, and surface topology results. Additionally, printed copper was more corrosion-resistant than wrought …
Mechanical Design Of A Microwave Imaging Device For Breast Cancer Detection In Mri Scanners, Grace M. Player
Mechanical Design Of A Microwave Imaging Device For Breast Cancer Detection In Mri Scanners, Grace M. Player
Dartmouth College Master’s Theses
This project seeks to develop an updated version of a microwave imaging device for use in conjunction with breast MRI, improving upon existing technology and developing novel concepts for the device. It posits three primary redesign targets for updating the previous system: resizing the system height, making the device more iteration- friendly, and improving the overall manufacturability of the device by replacing custom components with commercially available alternatives. All three of these redesign targets are met in the new design, V2.0. The height is reduced by reducing antenna travel and height, embedding some components, and shortening the tank wall, resulting …
Tensile Testing Of 3d Printed Tpu Samples For Pediatric Biomaterial Applications, Sheridan C. Perry, Rodriguez M. Rafael, Victor Huayamave, Bryan M. Gonzalez, Kim Dae-Won, Zachary R. Nadeau
Tensile Testing Of 3d Printed Tpu Samples For Pediatric Biomaterial Applications, Sheridan C. Perry, Rodriguez M. Rafael, Victor Huayamave, Bryan M. Gonzalez, Kim Dae-Won, Zachary R. Nadeau
PanaSoMM
Additive Manufacturing (AM) has, in recent years, become one of the most widespread and preferred prototyping methods. The most popular additive manufacturing method is Fused Deposition Modeling. FDM’s popularity is primarily attributed to its 3 major strengths of rapid prototyping, variability in material choice, and subject specific nature. The medical industry is one of the larger industries that has benefited from 3D printing especially in the terms of medical trainers. Unfortunately, most medical trainers that are developed (either being 3d printed or through traditional manufacturing processes) are poor substitutes for the human body. This can be attributed to either a …
Additive Manufacturing Of Variable Contrast Computed Tomography Anatomical Phantoms Using A Single Feedstock In Fused Filament Fabrication, Cory J. Darling
Additive Manufacturing Of Variable Contrast Computed Tomography Anatomical Phantoms Using A Single Feedstock In Fused Filament Fabrication, Cory J. Darling
University of New Orleans Theses and Dissertations
Anatomical phantoms used in biomedical education and training benefit greatly from Fused filament fabrication’s (FFF) ability to rapidly produce complex and unique models. Current materials and methods used in FFF have limited ability to accurately produce phantoms that can mimic the radiological properties of multiple biological tissues. This research demonstrates that the CT contrast of FFF produced models can be modified by varying the concentration of bismuth oxide in acrylonitrile butadiene styrene (ABS) filaments and a tunable CT contrast that mimics the CT contrast ranging from fatty tissue to cortical bone using a single composite filament without introducing artificial image …
Development Of A Wireless Telemetry Load And Displacement Sensor For Orthopaedic Applications, William Anderson
Development Of A Wireless Telemetry Load And Displacement Sensor For Orthopaedic Applications, William Anderson
Electronic Thesis and Dissertation Repository
Due to sensor size and supporting circuitry, in vivo load and deformation measurements are currently restricted to applications within larger orthopaedic implants. The objective of this thesis is to repurpose a commercially available low-power, miniature, wireless, telemetric, tire-pressure sensor (FXTH87) to measure load and deformation for future use in biomechanical applications. The capacitive transducer membrane of the FXTH87 was modified, and a relationship was reported between applied compressive deformation and sensor signal value. The sensor package was embedded within a deformable enclosure to illustrate potential applications of the sensor for monitoring load. Finite element analysis was an effective tool to …
Detection Of Nucleotides In Hydrated Ssdna Via 2-D H-Bn Nanopore With Ionic-Liquid/Salt-Water Interface, Jungsoo Lee
Detection Of Nucleotides In Hydrated Ssdna Via 2-D H-Bn Nanopore With Ionic-Liquid/Salt-Water Interface, Jungsoo Lee
Multidisciplinary Studies Theses and Dissertations
Accomplishing slow translocation speed with high sensitivity has been the greatest mission for solid-state nanopore (SSN) to electrically detect nucleobases in single-stranded DNA (ssDNA). In this study, a method to detect nucleobases in ssDNA using a SSN is introduced by considerably slowing down the translocation speed and effectively increasing its sensitivity. The ultra-thin titanium dioxide (TiO2) coated hexagonal boron nitride (h-BN) nanopore was fabricated, along with an ionic-liquid [bmim][PF6]/2.0 M KCl aqueous (cis/trans) interfacial system, to increase both the spatial and the temporal resolutions. As the ssDNA molecules entered the nanopore, a …
A Brief Bibliometric Survey On Circularly Polarized Antennas For Mobile Communication, Aniket Gunjal, Abhaya Pal Singh
A Brief Bibliometric Survey On Circularly Polarized Antennas For Mobile Communication, Aniket Gunjal, Abhaya Pal Singh
Library Philosophy and Practice (e-journal)
This paper presents a database review on “Circularly Polarized Antennas for Mobile Communication” as it is the emerging technique used by mobile service provider because of having benefits over other types of antennas available.The polarization purity is now the major issue. In some cases due to cross polarization issue the antenna signal is cancelled at receiver side.So, it is necessary to have circularly polarized antenna to avoid this polarization issue because of change in phase of signal. The change in phase of signal is due to striking of wave on the obstacles and it slightly tilted from its direction causes …
Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi S. Patel
Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi S. Patel
University Scholar Projects
Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.
Objective: Here, we establish a biodegradable, piezoelectric …
Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi Patel
Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi Patel
Honors Scholar Theses
Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.
Objective: Here, we establish a biodegradable, piezoelectric …
Methods To Remotely Eliminate Biofilm From Medical Implants Using 2.4 Ghz Microwaves, Brett Glenn
Methods To Remotely Eliminate Biofilm From Medical Implants Using 2.4 Ghz Microwaves, Brett Glenn
Mechanical Engineering Undergraduate Honors Theses
Infections associated with biofilm growth are usually challenging to eradicate due to their high tolerance toward antibiotics [11, 12]. Biofilms often form on the inert surfaces of medically implanted devices [13]. No matter the sophistication, microbial infections can develop on all medical devices and tissue engineering constructs [12]. Related infections lead to 2 million cases annually in the U.S., costing the healthcare system over $5 billion in additional healthcare expenses [12].
Novel solutions to biofilm’s microbial colonization span the spectrum of engineering and science disciplines. Yet a practical solution still does not exist. The research presented here will explore a …
The Effect Of Proteome And Lipidome On The Behavior Of Membrane Bound Systems In Thermally-Assisted Acoustophoresis, Elnaz Mirtaheri
The Effect Of Proteome And Lipidome On The Behavior Of Membrane Bound Systems In Thermally-Assisted Acoustophoresis, Elnaz Mirtaheri
FIU Electronic Theses and Dissertations
Changes in the biomechanical properties of cells accompanying the development of various pathological conditions have been increasingly reported as biomarkers for various diseases, including cancers. In cancer cells, the membrane properties have been altered compared to their healthy counterparts primarily due to proteomic and lipidomic dysregulations conferred by the underlying pathology. The separation and selective recovery of these cells or extracellular vesicles secreted from such cells is of high diagnostic and prognostic value.
In this dissertation, the research builds on thermally-assisted acoustophoresis technique which was developed in our laboratory for the separation of vesicles of the same size, charge and …
Analysis Of The Low-Cycle Fatigue Behavior Of Silicone Rubber For Biomedical Balloons, Chase Cooper
Analysis Of The Low-Cycle Fatigue Behavior Of Silicone Rubber For Biomedical Balloons, Chase Cooper
Materials Engineering
The development of a medical drug delivery device that allows for the deployment drugs into the adventitial tissue of blood vessels requires the inflation of a silicone elastomer. The inflated silicone must be able to consistently endure multiple loading cycles without failing so that the device can operate reliably. There are multiple methods of processing the silicone for the device and the goal of this study is to examine the effect of the various processing methods on the characteristics of the silicone. The Dynamic Mechanical Analysis Machine (DMA) is used to model the conditions of the device’s application by performing …
Enhanced Hot Electron Lifetimes In Quantum Wells With Inhibited Phonon Coupling, Hamidreza Esmaielpour, Vincent R. Whiteside, Herath P. Piyathilaka, Sangeetha Vijeyaragunathan, Bin Wang, Echo Adcock-Smith, Kenneth P. Roberts, Tetsuya D. Mishima, Michael B. Santos, Alan D. Bristow, Ian R. Sellers
Enhanced Hot Electron Lifetimes In Quantum Wells With Inhibited Phonon Coupling, Hamidreza Esmaielpour, Vincent R. Whiteside, Herath P. Piyathilaka, Sangeetha Vijeyaragunathan, Bin Wang, Echo Adcock-Smith, Kenneth P. Roberts, Tetsuya D. Mishima, Michael B. Santos, Alan D. Bristow, Ian R. Sellers
Faculty & Staff Scholarship
Hot electrons established by the absorption of high-energy photons typically thermalize on a picosecond time scale in a semiconductor, dissipating energy via various phonon-mediated relaxation pathways. Here it is shown that a strong hot carrier distribution can be produced using a type-II quantum well structure. In such systems it is shown that the dominant hot carrier thermalization process is limited by the radiative recombination lifetime of electrons with reduced wavefunction overlap with holes. It is proposed that the subsequent reabsorption of acoustic and optical phonons is facilitated by a mismatch in phonon dispersions at the InAs-AlAsSb interface and serves to …
Can A Comprehensive Transition Plan To Barefoot Running Be The Solution To The Injury Epidemic In American Endurance Runners?, Michael A. Scarlett
Can A Comprehensive Transition Plan To Barefoot Running Be The Solution To The Injury Epidemic In American Endurance Runners?, Michael A. Scarlett
CMC Senior Theses
Fossils belonging to the genus Homo, dating as far back as two million years ago, exhibit uniquely efficient features suggesting that early humans had evolved to become exceptional endurance runners. Although they did not have the cushion or stability-control features provided in our modern day running shoes, our early human ancestors experienced far less of the running-related injuries we experience today. The injury rate has been estimated as high as 90% annually for Americans training for a marathon and as high as 79% annually for all American endurance runners. There is an injury epidemic in conventionally shod populations that …
Redesign Of Computer Keyboards For Hospital And Consumer Use, Kent Williams, Brian Jensen, Anton Bowden
Redesign Of Computer Keyboards For Hospital And Consumer Use, Kent Williams, Brian Jensen, Anton Bowden
Biomedical Engineering Western Regional Conference
Application of carbon nanotube coatings to computer keyboards in order to reduce the spread of bacteria in hospitals and homes.
Keywords: carbon nanotube, bacteria, antimicrobial, keyboard, design, MRSA, biofilm
Effects Of Antidepressants On Human Mesenchymal Stem Cell Differentiation On Clinically Relevant Titanium Surfaces, Nancy B. Ayad
Effects Of Antidepressants On Human Mesenchymal Stem Cell Differentiation On Clinically Relevant Titanium Surfaces, Nancy B. Ayad
Theses and Dissertations
Selective Serotonin Reuptake Inhibitors (SSRIs) are the most frequently prescribed class of drugs worldwide and are implemented in the treatment of depression and other psychiatric disorders. SSRIs relieve depressive symptoms by modulating levels of the neurotransmitter serotonin in the brain. SSRIs block the function of the serotonin transporter, thereby increasing concentrations of extracellular serotonin. However, serotonin levels in the neurons of the brain only account for 5% while the remaining 95% is present outside the brain. Serotonin receptors and transporter are located on bone resident cells (mesenchymal stem cells (MSCs)), osteoblasts and osteoclasts, and serotonergic activity is believed to affect …
The Role Of Biological Fluid And Dynamic Flow In The Behavior And Cellular Interactions Of Gold Nanoparticles, Emily K. Breitner, Saber M. Hussain, Kristen K. Comfort
The Role Of Biological Fluid And Dynamic Flow In The Behavior And Cellular Interactions Of Gold Nanoparticles, Emily K. Breitner, Saber M. Hussain, Kristen K. Comfort
Chemical and Materials Engineering Faculty Publications
Background: Due to their distinctive physicochemical properties, nanoparticles (NPs) have proven to be extremely advantageous for product and application development, but are also capable of inducing detrimental outcomes in biological systems. Standard in vitro methodologies are currently the primary means for evaluating NP safety, as vast quantities of particles exist that require appraisal. However, cell-based models are plagued by the fact that they are not representative of complex physiological systems. The need for a more accurate exposure model is highlighted by the fact that NP behavior and subsequent bioresponses are highly dependent upon their surroundings. Therefore, standard in vitro models …
Three-Dimensional Confocal Microscopy Indentation Method For Hydrogel Elasticity Measurement, Donghee Lee, Md Mahmudur Rahman, You Zhou, Sangjin Ryu
Three-Dimensional Confocal Microscopy Indentation Method For Hydrogel Elasticity Measurement, Donghee Lee, Md Mahmudur Rahman, You Zhou, Sangjin Ryu
Md Mahmudur Rahman
No abstract provided.
Self-Contained Breathing Apparatus For Firefighter With A Permanent Stoma, Jason Delgadillo, Aaron Wheeler, Zachary Wishbow
Self-Contained Breathing Apparatus For Firefighter With A Permanent Stoma, Jason Delgadillo, Aaron Wheeler, Zachary Wishbow
Biomedical Engineering
The purpose of this project was to create a unique SCBA (self-contained breathing apparatus) for a firefighter named Chris Gauer. This prototype consists of a SCBA headgear connected to a polycarbonate-formed stoma mask with a medical-grade sanitary silicone hose.
Engineering The “Pluripotency” Of Zr-Based Bulk Metallic Glasses As Biomedical Materials, Lu Huang
Engineering The “Pluripotency” Of Zr-Based Bulk Metallic Glasses As Biomedical Materials, Lu Huang
Doctoral Dissertations
Bulk metallic glasses (BMGs) are a family of novel alloys with amorphous microstructures. The combination of their excellent mechanical properties, good chemical stability, high thermal formability, and general biocompatibility has brought up new opportunities for biomaterials. Research in this dissertation was focused on exploring multiple biomedical functionalities of Zr-based BMGs over a wide spectrum, combining materials and biological characterizations, through experimental and computational approaches. Four distinct yet interconnected tasks were endeavored, involving inflammation, hard-tissue implant, soft-tissue prosthesis, and pathogenic infection.
The inflammation that can be potentially triggered by Zr-based BMGs was investigated using macrophages. Lower level or comparable macrophage activations …
In-Vivo Corrosion And Fretting Of Modular Ti-6al-4v/Co-Cr-Mo Hip Prostheses: The Influence Of Microstructure And Design Parameters, Jose Luis Gonzalez Jr
In-Vivo Corrosion And Fretting Of Modular Ti-6al-4v/Co-Cr-Mo Hip Prostheses: The Influence Of Microstructure And Design Parameters, Jose Luis Gonzalez Jr
FIU Electronic Theses and Dissertations
The purpose of this study was to evaluate the incidence of corrosion and fretting in 48 retrieved titanium-6aluminum-4vanadium and/or cobalt-chromium-molybdenum modular total hip prosthesis with respect to alloy material microstructure and design parameters. The results revealed vastly different performance results for the wide array of microstructures examined. Severe corrosion/fretting was seen in 100% of as-cast, 24% of low carbon wrought, 9% of high carbon wrought and 5% of solution heat treated cobalt-chrome. Severe corrosion/fretting was observed in 60% of Ti-6Al-4V components. Design features which allow for fluid entry and stagnation, amplification of contact pressure and/or increased micromotion were also shown …
Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications, Logan Grimes
Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications, Logan Grimes
Master's Theses
The American Cancer Society predicts that 1,665,540 people will be diagnosed with cancer, and 585,720 people will die from cancer in 2014. One of the most common types of cancer in the United States is skin cancer. Melanoma alone is predicted to account for 10,000 of the cancer related deaths in 2014. As a highly mobile and aggressive form of cancer, melanoma is difficult to fight once it has metastasized through the body. Early detection in such varieties of cancer is critical in improving survival rates in afflicted patients. Present methods of detection rely on visual examination of suspicious regions …
Magnesium-Titanium Alloys For Biomedical Applications, Ilona Hoffmann
Magnesium-Titanium Alloys For Biomedical Applications, Ilona Hoffmann
Theses and Dissertations--Chemical and Materials Engineering
Magnesium has been identified as a promising biodegradable implant material because it does not cause systemic toxicity and can reduce stress shielding. However, it corrodes too quickly in the body. Titanium, which is already used ubiquitously for implants, was chosen as the alloying element because of its proven biocompatibility and corrosion resistance in physiological environments. Thus, alloying magnesium with titanium is expected to improve the corrosion resistance of magnesium.
Mg-Ti alloys with a titanium content ranging from 5 to 35 at.-% were successfully synthesized by mechanical alloying. Spark plasma sintering was identified as a processing route to consolidate the alloy …
Physiological Fluid Specific Agglomeration Patterns Diminish Gold Nanorod Photothermal Characteristics, Kristen K. Comfort, Jared W. Speltz, Bradley M. Stacy, Larry R. Dosser, Saber M. Hussain
Physiological Fluid Specific Agglomeration Patterns Diminish Gold Nanorod Photothermal Characteristics, Kristen K. Comfort, Jared W. Speltz, Bradley M. Stacy, Larry R. Dosser, Saber M. Hussain
Chemical and Materials Engineering Faculty Publications
Investigations into the use of gold nanorods (Au-NRs) for biological applications are growing exponentially due to their distinctive physicochemical properties, which make them advantageous over other nanomaterials. Au-NRs are particularly renowned for their plasmonic characteristics, which generate a robust photothermal response when stimulated with light at a wavelength matching their surface plasmon resonance. Numerous reports have explored this nanophotonic phenomenon for temperature driven therapies; however, to date there is a significant knowledge gap pertaining to the kinetic heating profile of Au-NRs within a controlled physiological setting. In the present study, the impact of environmental composition on Au-NR behavior and degree …
Materials Education And Research In Art And Design: A New Role For Libraries (Website), Mark Pompelia
Materials Education And Research In Art And Design: A New Role For Libraries (Website), Mark Pompelia
Materials Education and Research in Art and Design: A New Role for Libraries
No abstract provided.
Materials Education And Research In Art And Design: A New Role For Libraries (Program Sheet), Mark Pompelia
Materials Education And Research In Art And Design: A New Role For Libraries (Program Sheet), Mark Pompelia
Materials Education and Research in Art and Design: A New Role for Libraries
No abstract provided.
Materials Education And Research In Art And Design: A New Role For Libraries (Program Booklet), Mark Pompelia
Materials Education And Research In Art And Design: A New Role For Libraries (Program Booklet), Mark Pompelia
Materials Education and Research in Art and Design: A New Role for Libraries
No abstract provided.
Materials Education And Research In Art And Design: A New Role For Libraries (Survey Stats), Mark Pompelia
Materials Education And Research In Art And Design: A New Role For Libraries (Survey Stats), Mark Pompelia
Materials Education and Research in Art and Design: A New Role for Libraries
No abstract provided.
Materials Collection Creation And Administration: A New Role For Libraries (White Paper), Mark Pompelia
Materials Collection Creation And Administration: A New Role For Libraries (White Paper), Mark Pompelia
Materials Education and Research in Art and Design: A New Role for Libraries
The Problem/Opportunity: To define, identify, and guide design-based materials collections in academic settings and foster community among those with existing collections and/or those considering creating and supporting one.
Contents and topics:
- What is a materials collection?
- Why have a materials collection?
- Acquisition strategies
- Organizational approaches
- Programming possibilities
- Symposium summary
- Resources
Fluorescence Characterization Of Quantum Dots For Use As Biomarkers, Logan M. Grimes
Fluorescence Characterization Of Quantum Dots For Use As Biomarkers, Logan M. Grimes
Materials Engineering
Fluorescence profiles of quantum dots (QDs) were characterized to select the ideal QDs for encapsulation in phospholipids for use as biomarkers to selectively adhere to cancer cells. QDs were synthesized and extracted 0, 30, 60, and 90 seconds after precursor compounds were mixed. These extractions were isolated by extraction time. Portions from each vial were coated in a zinc sulfide shelling procedure, leaving at least half of the QD solution unshelled. These samples were characterized over four days to monitor fluctuations in fluorescence. This was done utilizing an Ocean Optics spectrometer in conjunction with Spectra Suite software. The central wavelength, …