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Full-Text Articles in Biomedical Engineering and Bioengineering

A Comprehensive Analysis Of Balance, Symmetry, And Center Of Mass In The Gait Cycle Of Transfemoral Amputees, Kayla T. Etienne Jul 2020

A Comprehensive Analysis Of Balance, Symmetry, And Center Of Mass In The Gait Cycle Of Transfemoral Amputees, Kayla T. Etienne

FIU Electronic Theses and Dissertations

The purpose of this thesis is to create a framework that assists in the transfemoral prosthesis fitting process by calculating balance and symmetry to quantify patient comfort with an understanding of bipedal locomotion and human anatomy. Three different software applications were used to compare (1) the body position during gait cycle, (2) the natural and amputee anatomies, (3) the natural and prosthetic legs, and (4) the equilibrium and torque movements of the hip, knee, and ankle joints. Models were created in Maya for analysis in Solidworks and MEL code evaluation with MatLab. The MatLab code tested combinations of joint degrees …


3d Architectural Analysis Of Neurons, Astrocytes, Vasculature & Nuclei In The Motor And Somatosensory Murine Cortical Columns, Jared Leichner Jul 2020

3d Architectural Analysis Of Neurons, Astrocytes, Vasculature & Nuclei In The Motor And Somatosensory Murine Cortical Columns, Jared Leichner

FIU Electronic Theses and Dissertations

Characterization of the complex cortical structure of the brain at a cellular level is a fundamental goal of neuroscience which can provide a better understanding of both normal function as well as disease state progression. Many challenges exist however when carrying out this form of analysis. Immunofluorescent staining is a key technique for revealing 3-dimensional structure, but subsequent fluorescence microscopy is limited by the quantity of simultaneous targets that can be labeled and intrinsic lateral and isotropic axial point-spread function (PSF) blurring during the imaging process in a spectral and depth-dependent manner. Even after successful staining, imaging and optical deconvolution, …


Development Of Gaussian Learning Algorithms For Early Detection Of Alzheimer's Disease, Chen Fang Mar 2020

Development Of Gaussian Learning Algorithms For Early Detection Of Alzheimer's Disease, Chen Fang

FIU Electronic Theses and Dissertations

Alzheimer’s disease (AD) is the most common form of dementia affecting 10% of the population over the age of 65 and the growing costs in managing AD are estimated to be $259 billion, according to data reported in the 2017 by the Alzheimer's Association. Moreover, with cognitive decline, daily life of the affected persons and their families are severely impacted. Taking advantage of the diagnosis of AD and its prodromal stage of mild cognitive impairment (MCI), an early treatment may help patients preserve the quality of life and slow the progression of the disease, even though the underlying disease cannot …