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Surface Acoustic Wave-Based Manipulation Of Intracellular Structures In Adherent Cultured Cells, Jeffrey Servetas
Surface Acoustic Wave-Based Manipulation Of Intracellular Structures In Adherent Cultured Cells, Jeffrey Servetas
Honors College
A method for manipulating constituents of cells through the use of surface acoustic wave (SAW) devices is investigated. Cells are allowed to adhere to the gold surface of a SAW device, and the device is then operated at low power, with the intention of altering the distribution or activity of intracellular structures or organelles, while avoiding damage, or cell death. The method is compared to alternatives, such as optical tweezers, and pulsatile electrical stimulation.