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2005

Selected Works

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Articles 31 - 60 of 70

Full-Text Articles in Engineering

Genome-Wide Requirements For Resistance To Functionally Distinct Dna-Damaging Agents, Patrick Flaherty Jul 2005

Genome-Wide Requirements For Resistance To Functionally Distinct Dna-Damaging Agents, Patrick Flaherty

Patrick Flaherty

The mechanistic and therapeutic differences in the cellular response to DNA-damaging compounds are not completely understood, despite intense study. To expand our knowledge of DNA damage, we assayed the effects of 12 closely related DNA-damaging agents on the complete pool of ;4,700 barcoded homozygous deletion strains of
Saccharomyces cerevisiae. In our protocol, deletion strains are pooled together and grown competitively in the presence of compound. Relative strain sensitivity is determined by hybridization of PCR-amplified barcodes to an oligonucleotide array carrying the barcode complements. These screens identified genes in well-characterized DNAdamage-response pathways as well as genes whose role in the …


A Latent Variable Model For Chemogenomic Profiling, Patrick Flaherty Jul 2005

A Latent Variable Model For Chemogenomic Profiling, Patrick Flaherty

Patrick Flaherty

Motivation: In haploinsufficiency profiling data, pleiotropic genes
are often misclassified by clustering algorithms that impose the constraint that a gene or experiment belong to only one cluster. We
have developed a general probabilistic model that clusters genes and
experiments without requiring that a given gene or drug only appear
in one cluster. The model also incorporates the functional annotation
of known genes to guide the clustering procedure.
Results: We applied our model to the clustering of 79 chemogenomic
experiments in yeast. Known pleiotropic genes PDR5 and MAL11 are
more accurately represented by the model than by a clustering procedure that …


Making Scotch: Its Engineering, Chemistry, And Education, J. Collier, Samuel Morton, T. Rogers, J. Mcewan, M. Reynier Jun 2005

Making Scotch: Its Engineering, Chemistry, And Education, J. Collier, Samuel Morton, T. Rogers, J. Mcewan, M. Reynier

Samuel A Morton

No abstract provided.


Real-Time Reconstruction Of Remote Sensing Imagery: Aggregation Of Robust Regularization With Neural Computing, Yuriy V. Shkvarko, Ivan E. Villalon-Turrubiates Jun 2005

Real-Time Reconstruction Of Remote Sensing Imagery: Aggregation Of Robust Regularization With Neural Computing, Yuriy V. Shkvarko, Ivan E. Villalon-Turrubiates

Iván Esteban Villalón Turrubiates

The robustified numerical technique for real-time sensor array reconstructive image processing is developed as required for remote sensing imaging with large scale array/synthesized array radars. The addressed technique is designed via performing the regularized robustification of the fused Bayesian-regularization imaging method aggregated with the efficient real-time numerical implementation scheme that employs the neural network computing.


Developing A Student Lead Undergraduate Environmental Research Organization: The Society Of Environmental Engineers And Scientists, P. Dimick, A. Baker, L. Vanzler, A. Kney, Samuel Morton, S. Mylon May 2005

Developing A Student Lead Undergraduate Environmental Research Organization: The Society Of Environmental Engineers And Scientists, P. Dimick, A. Baker, L. Vanzler, A. Kney, Samuel Morton, S. Mylon

Samuel A Morton

No abstract provided.


Integrating The Principles Of Green Engineering In The Project Based Process Synthesis Curriculum, Samuel Morton, R. Counce May 2005

Integrating The Principles Of Green Engineering In The Project Based Process Synthesis Curriculum, Samuel Morton, R. Counce

Samuel A Morton

No abstract provided.


Diode-Laser-Based Ultraviolet-Absorption Sensor For High-Speed Detection Of The Hydroxyl Radical, Thomas N. Anderson, Robert P. Lucht, Terrence R. Meyer, Sukesh Roy, James R. Gord May 2005

Diode-Laser-Based Ultraviolet-Absorption Sensor For High-Speed Detection Of The Hydroxyl Radical, Thomas N. Anderson, Robert P. Lucht, Terrence R. Meyer, Sukesh Roy, James R. Gord

Terrence R Meyer

A new diode-laser-based UV-absorption sensor for high-speed detection of the hydroxyl radical (OH) is described. The sensor is based on sum-frequency generation of UV radiation at 313.5 nm by mixing the output of a 763-nm distributed-feedback diode laser with that of a 532-nm high-power, diode-pumped, frequency-doubled Nd:YVO4 laser in a B-barium borate crystal.


Mining And Metallurgical Heritage, Fathi Habashi May 2005

Mining And Metallurgical Heritage, Fathi Habashi

Fathi Habashi

A research unit entitled “Mining and Metallurgical Heritage” has been recently created at Laval University in Quebec City, whose purpose is to collect and disseminate information about the history of mining and metallurgy and to emphasize the importance of heritage awareness. The research unit is soliciting donations and financial support from industry, government, and individuals in addition to the moral support. Summary in Mining Engineering March 2005, page 15. A French summary in Trait D'Union [Laval University] March 2005, page 15.


Jual Obat Bius Di Timika 082313333253 Alamat Apotik Jual Obat Bius/ Tidur Di Timika, Toko Afeng Obat Kuat Bogor May 2005

Jual Obat Bius Di Timika 082313333253 Alamat Apotik Jual Obat Bius/ Tidur Di Timika, Toko Afeng Obat Kuat Bogor

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High Speed Flight At Low Altitude - Hazard To Commercial Aviation?, Paul F. Eschenfelder Apr 2005

High Speed Flight At Low Altitude - Hazard To Commercial Aviation?, Paul F. Eschenfelder

Paul F. Eschenfelder

No abstract provided.


Digital Calculation Of Frequency Of Periodical Signal (Sinusoidal And Triangular, Tarak Benslimane, Boukhemis Chetate Apr 2005

Digital Calculation Of Frequency Of Periodical Signal (Sinusoidal And Triangular, Tarak Benslimane, Boukhemis Chetate

Boukhemis Chetate

– In This paper, a method of digital calculation of frequency of periodical signal (sinusoidal, triangular and square signals) is proposed. This method is based on calculation of time between two successive peaks of the rectified signal which constitutes it’s half period. This method allows the measurement of AC current and voltage of AC electrical network. To apply this method, it is necessary to have current and voltage sensors, analogue/ digital converter (ADC) and a processor. A software C++ based program is developed which can be implemented using appropriate processor. In the end are presented the digital simulation results.


Citizen Based Public Health Surveillance, Monitoring And Post-Event Assessments, Thomas Lyons Carr Iii Apr 2005

Citizen Based Public Health Surveillance, Monitoring And Post-Event Assessments, Thomas Lyons Carr Iii

Thomas Lyons (Thom) Carr III Appl.Sc., CEM

When a sudden on-set emergency or disaster affects a region or the whole country, communities and neighborhoods should plan for the possibility that emergency and other civic services will be disrupted and unavailable (District of Columbia 2003a, 2003b, 2004; Doyle 2004; Siskiyou County Public Health/NorCalBT.com 2004). The event may be severe enough that the routine public health surveillance and monitoring system will be disrupted or the system will not be able to provide data quickly enough to support state and local decisionmaking. A temporary post-disaster system should be planned for and implemented. The epidemiologist supporting the local decision makers must …


Nanophotonics – From The Laboratory To Commercialization, Andrew Sarangan Mar 2005

Nanophotonics – From The Laboratory To Commercialization, Andrew Sarangan

Andrew Sarangan

University of Dayton Sigma Xi Annual Lecture and Banquet


A Minimal Model For The Helix-Coil Transition Of Worm-Like Polymers, Gustavo Carri Mar 2005

A Minimal Model For The Helix-Coil Transition Of Worm-Like Polymers, Gustavo Carri

Gustavo A. Carri

We present a geometric approach to the simulation of the Helix-Coil transition in wormlike polymers. In our model, the polymer is treated as a Freely Rotating Chain with hard-core repulsion between beads. The conformational state (helix or coil) of each bead is determined by the value of its torsion. If the difference between the torsion of a bead and the one of the perfect helix is less than a cutoff value, then the bead is part of a helical domain and carries a negative energy, otherwise it is part of a random coil. We have simulated these concepts using the …


Analysis On Energy Consumption And Performance Of Reheating Furnaces In A Hot Strip Mill, Wei-Hsin Chen Mar 2005

Analysis On Energy Consumption And Performance Of Reheating Furnaces In A Hot Strip Mill, Wei-Hsin Chen

Wei-Hsin Chen

No abstract provided.


Keyboards For Inputting Japanese Language: A Study Based On Us Patents, Umakant Mishra Mar 2005

Keyboards For Inputting Japanese Language: A Study Based On Us Patents, Umakant Mishra

Umakant Mishra

The most commonly used Japanese alphabets are Kanji, Hiragana and Katakana. The Kanji alphabet includes pictographs or ideographic characters that were adopted from the Chinese alphabet. Hiragana is used to spell words of Japanese origin, while Katakana is used to spell words of western or other foreign origin.

Two methods are commonly used to input Japanese to the computer. One, the “kana input method” that uses a keyboard having 46 Japanese iroha (or kana) letter keys. The other method is “Roma-ji input method”, where the Japanese letters are composed of English input from a standard QWERTY keyboard. Both the methods …


Mil-Std-188-125-1, High-Altitude Emp Protection For Fixed Ground-Based Facilities Mar 2005

Mil-Std-188-125-1, High-Altitude Emp Protection For Fixed Ground-Based Facilities

George H Baker

MIL-STD-188-125-1 establishes minimum requirements and design objectives for high-altitude electromagnetic pulse (HEMP) hardening of fixed ground-based facilities that perform critical, time-urgent command, control, communications, computer, and intelligence (C4I) missions. The standard prescribes minimum performance requirements for low-risk protection from mission-aborting damage or upset due to HEMP environments. It also addresses minimum testing requirements for demonstrating that prescribed performance has been achieved and for verifying that the installed protection subsystem provides the operationally required hardness for the completed facility. Covered fixed ground-based facility types include subscriber terminals and data processing centers, transmitting and receiving communications stations, and relay facilities. Use of …


10 Inventions On Reducing Keyboard Size, Umakant Mishra Feb 2005

10 Inventions On Reducing Keyboard Size, Umakant Mishra

Umakant Mishra

A conventional computer keyboard consists of as many as 101 keys. The keyboard has several sections, such as text entry section, navigation section, and numeric keypad etc. and each having several keys on the keyboard. The size of the keyboard is a major inconvenience for portable computers, as they cannot be carried easily. Thus there are certain circumstances which compels to reduce the size of a keyboard. Reducing the size of a keyboard leads to several problems. A reduced size keyboard may not contain all the keys available on a full size keyboard; a reduced size keyboard may not be …


What Communities Should Do Pre-Event To Support Public Health Post-Event Assessments, Surveillance And Monitoring, Thomas Lyons Carr Iii Feb 2005

What Communities Should Do Pre-Event To Support Public Health Post-Event Assessments, Surveillance And Monitoring, Thomas Lyons Carr Iii

Thomas Lyons (Thom) Carr III Appl.Sc., CEM

[Abstract written March 2008, TLC] Under worst-case planning assumptions used by some major metropolitan areas, a Neighbor-to-Neighbor self-help program model is the primary link between citizens and the professional response personnel of the responsible government agencies.

In the Neighbor-to-Neighbor self-help program model or a Community Emergency Management Plan (CEMP) calls on the citizens in neighborhoods to identify and establish cluster emergency preparedness committees, Cluster Emergency Coordination Centers (CECC) and Community Emergency Response Teams (CERT). Missing from these plans or what is not articulated is how constant Public Health Post-Event Surveillance, Monitoring and Assessments will be done. Given the worst-case planning …


Inkjet Printing Of Viable Mammalian Cells, Tao Xu, Joyce Jin, Cassie Gregory, Jay Hickman, Thomas Boland Dec 2004

Inkjet Printing Of Viable Mammalian Cells, Tao Xu, Joyce Jin, Cassie Gregory, Jay Hickman, Thomas Boland

Thomas Boland

The purpose of this study was to explore the use of a commercial thermal printer to deposit Chinese Hamster Ovary (CHO) and embryonic motoneuron cells into pre-defined patterns. These experiments were undertaken to verify the biocompatibility of thermal inkjet printing of mammalian cells and the ability to assemble them into viable constructs. Using a modified Hewlett Packard (HP) 550C computer printer and an HP 51626a ink cartridge, CHO cells and rat embryonic motoneurons were suspended separately in a concentrated phosphate buffered saline solution (3 x). The cells were subsequently printed as a kind of "ink" onto several "bio-papers" made from …


Cluster Treatment Of Characteristic Roots, Ctcr, A Unique Methodology For The Complete Robustness Analysis Of Linear Time Invariant Multiple Time Delay Systems Against Delay Uncertainties, Rifat Sipahi Dec 2004

Cluster Treatment Of Characteristic Roots, Ctcr, A Unique Methodology For The Complete Robustness Analysis Of Linear Time Invariant Multiple Time Delay Systems Against Delay Uncertainties, Rifat Sipahi

Rifat Sipahi

Today, many high-tech applications such as simultaneous metal machining, neural networks, internet data congestion, population dynamics, chemical processes, formation flight problems, etc., appear in the form of multiple time delay systems (MTDS ). Due to the presence of delays, the stability of the dynamics is under question and needs to be addressed. In the last four decades, the stability analysis of the general class, Linear Time Invariant MTDS (LTI-MTDS), has been one of the challenging problems of the systems and control community, which originates from the complex stability analysis due to their infinite dimensionality. For tackling this, a unique procedure …


Constraint Programming, John Hooker Dec 2004

Constraint Programming, John Hooker

John Hooker

No abstract provided.


Runoff Production In The Upper Rio Chagres Watershed, Panama, Fred Ogden Dec 2004

Runoff Production In The Upper Rio Chagres Watershed, Panama, Fred Ogden

Fred L. Ogden

Runoff production in tropical watersheds is governed by a wide variety of potential sources and there have been few rigorous studies to date. The 414 km2 upper Río Chagres basin offers a unique opportunity to better understand the runoff production mechanisms in tropical watersheds through data analysis and modeling with rainfall and runoff data. Flow data and tipping bucket rain gage data are available at both the basin outlet (Chico gage) and for an 80.6 km2 internal basin location (Piedras gage). Modeling is performed using the Sacramento Soil Moisture Accounting Model (SAC-SMA), calibrated using data from 2000 and verified using …


Convex Programming Methods For Global Optimization, John Hooker Dec 2004

Convex Programming Methods For Global Optimization, John Hooker

John Hooker

No abstract provided.


Study On Improving The Opacity Of Paper Using Adjunct Filler Pigments, Pankaj Chowdhury, Puskar Gupta, Manoj Kumar, Pramod Bajpai, Raghavan Varadhan Dec 2004

Study On Improving The Opacity Of Paper Using Adjunct Filler Pigments, Pankaj Chowdhury, Puskar Gupta, Manoj Kumar, Pramod Bajpai, Raghavan Varadhan

PC

No abstract provided.


Platform Thinking In Embedded Systems, Robert Iannucci Dec 2004

Platform Thinking In Embedded Systems, Robert Iannucci

Robert A Iannucci

No abstract provided.


Advances In Tissue Engineering: Cell Printing, David Varghese, Malay Deshpande, Priya Kesari, S Ohri, Thomas Boland Dec 2004

Advances In Tissue Engineering: Cell Printing, David Varghese, Malay Deshpande, Priya Kesari, S Ohri, Thomas Boland

Thomas Boland

No abstract provided.


Development Of A Service Learning Geohazards Class In Ecuador, Raúl Ordóñez Dec 2004

Development Of A Service Learning Geohazards Class In Ecuador, Raúl Ordóñez

Raúl Ordóñez

Co-PI, UD, $8,500.


Modular Teaching And Product Design Projects In Capstone Design, Yasar Demirel Dec 2004

Modular Teaching And Product Design Projects In Capstone Design, Yasar Demirel

YASAR DEMIREL

Some latest employment surveys show that chemical engineers are working in more and more diverse industries. For example, some of them design and manufacture specialty products, and need to understand property-structure relationships using chemistry, biology, and physics. Therefore, modular teaching with specialty product design projects would be useful, and should be integrated into the capstone design. Modular teaching can provide a means of responding to diverse and fast changing course contents and learning/teaching objectives. Product design projects come in various categories, such as separations, heat and mass transfer, kinetics, thermodynamics, or biotechnology, and incorporate DMAIC (Define, Measure, Analyze, Improve, Control) …


Stability Of Transport And Rate Processes, Yasar Demirel Dec 2004

Stability Of Transport And Rate Processes, Yasar Demirel

YASAR DEMIREL

About fifty years ago, the Turing instability demonstrated that even simple reaction-diffusion systems might lead to spatial order and differentiation, while the Rayleigh-Bénard instability showed that the maintenance of nonequilibrium might be the source of order in fluids subjected to a thermodynamic force above a critical value. Therefore, distance from global equilibrium in the form of magnitude of a thermodynamic force emerges as another constraint of stability; some systems may enhance perturbations, and evolve to highly organized states called the dissipative structures after a critical distance on the thermodynamic branch. Although the kinetics and transport coefficients represent short-range interactions, chemical …