Engineering Commons^™

Osaka University: A Focus Of Polymer Science: 70th Anniversary Celebration, Otto Vogl, Koichi Hatada

Emeritus Faculty Author Gallery

No abstract provided.

Personalities In Polymer Science: Cover Page, Title Page, Introduction, And List Of Articles, Otto Vogl

Emeritus Faculty Author Gallery

A compilation of articles with short biographies of the scientists who played leading roles in the field and provided the basis of Polymer Science and Technology throughout the 20th century.

Cell Population Modelling Of Yeast Glycolytic Oscillations, Michael A. Henson, Dirk Muller, Matthias Reuss

Michael A Henson

We investigated a cell-population modelling technique in which the population is constructed from an ensemble of individual cell models. The average value or the number distribution of any intracellular property captured by the individual cell model can be calculated by simulation of a sufficient number of individual cells. The proposed method is applied to a simple model of yeast glycolytic oscillations where synchronization of the cell population is mediated by the action of an excreted metabolite. We show that smooth one-dimensional distributions can be obtained with ensembles comprising 1000 individual cells. Random variations in the state and}or structure of individual …

Osaka University: A Focus Of Polymer Science: 70th Anniversary Celebration, Otto Vogl, Koichi Hatada

Otto Vogl

No abstract provided.

Personalities In Polymer Science: Cover Page, Title Page, Introduction, And List Of Articles, Otto Vogl

Otto Vogl

A compilation of articles with short biographies of the scientists who played leading roles in the field and provided the basis of Polymer Science and Technology throughout the 20th century.

Self-Consistent Three Dimensional Models For Quantum Ballistic Transport In Open Systems, Eric Polizzi, N. Ben Abdallah

Eric Polizzi

A quasi-three-dimensional model for quantum ballistic transport in nanostructures is proposed. The model goes beyond the Thomas-Fermi approximation and is numerically more tractable than the full three-dimensional Schrödinger-Poisson model. Its derivation relies on the strong confinement of electrons at the heterojunction which allows us to split the three-dimensional Schrödinger equation into a one-dimensional Schrödinger equation for the confined direction and a two-dimensional Schrödinger equation in the transport direction. The space charge effects are taken into account in a three-dimensional framework. Numerical simulations of quantum waveguide devices such as T stubs and directional couplers are used to illustrate the accuracy of …

The Use Of 4-Substituted Pyridines To Afford Amphiphilic, Pegylated Cadmium Selenide Nanoparticles, Habib Skaff, Todd S. Emrick

Todd S. Emrick

Amphiphilic cadmium selenide (CdSe) nanoparticles were prepared by surface functionalization with novel ligands 1 and 2, composed of pyridine moieties substituted in the 4-position with polyethylene glycol (PEG) chains.

1. Yukio Imanishi, Otto Vogl

Emeritus Faculty Author Gallery

No abstract provided.

1. Yukio Imanishi, Otto Vogl

Otto Vogl

No abstract provided.

2. Toshinobu Higashimura, Otto Vogl

Emeritus Faculty Author Gallery

No abstract provided.

2. Toshinobu Higashimura, Otto Vogl

Otto Vogl

No abstract provided.

3. Otto Vogl, Gerald S. Kirshenbaum, Helga Roder

Emeritus Faculty Author Gallery

No abstract provided.

3. Otto Vogl, Gerald S. Kirshenbaum, Helga Roder

Otto Vogl

No abstract provided.

Using Small Group Assignments In Teaching Research Ethics, Kenneth D. Pimple

Ethics in Science and Engineering National Clearinghouse

No abstract provided.

Using Short Writing Assignments In Teaching Research Ethics, Kenneth D. Pimple

Ethics in Science and Engineering National Clearinghouse

Regularly asking students to write down their thoughts and reactions to class readings and discussions is an effective method of teaching and assessing student learning. Furthermore, as composition teachers will attest, frequent writing assignments, regardless of content, dramatically improve writing skills. Asking students to think “on paper” about topics encountered in the classroom encourages them to think about those topics in greater depth, relate them to their own lives, and thus connect the classroom to the world outside. I will describe four kinds of useful short writing assignments – freewriting, the non-quiz, the one-minute paper, and logbooks.

Spsj 50th Annual Meeting, Osaka, Japan, May 23-25, 2001, Otto Vogl, Yasuhiko Shirota, Tatsuro Ouchi

Emeritus Faculty Author Gallery

No abstract provided.

Dynamics And Control Of Cell Populations In Continuous Bioreactors, Prodromos Daoutidis, Michael A. Henson

Michael A Henson

Continuous bioreactors are critical unit operations in a wide variety of biotechnological processes. While they can be viewed as chemical reactors, bioreactors offer unique modeling and control challenges due to the complexity of the underlying biochemical reactions and the distributed properties of the cell population. The dynamic behavior of continuous bioreactors can be strongly affected by variations between individual cells that are captured only with cell population models. The objective of this paper is to outline recent progress in dynamic analysis and feedback control of continuous bioreactors described by cell population models. The industrially important process of continuous yeast production …

Cell Population Modeling And Parameter Estimation For Continuous Cultures Of Saccharomyces Cerevisiae, Prashant Mhaskar, Martin A. Hjortse, Michael A. Henson

Michael A Henson

Saccharomyces cerevisiae is known to exhibit sustained oscillations in chemostats operated under aerobic and glucose-limited growth conditions. The oscillations are reflected both in intracellular and extracellular measurements. Our recent work has shown that unstructured cell population balance models are capable of generating sustained oscillations over an experimentally meaningful range of dilution rates. A disadvantage of such unstructured models is that they lack variables that can be compared directly to easily measured extracellular variables. Thus far, most of our work in model development has been aimed at achieving qualitative agreement with experimental data. In this paper, a segregated model with a …

De Novo Design Of Biomimetic Antimicrobial Polymers, Gregory N. Tew, Dahui Liu, Bin Chen, Robert J. Doerksen, Justin Kaplan, Patrick J. Carroll, Michael L. Klein, William F. Degrado

Gregory N. Tew

The design of polymers and oligomers that mimic the complex structures and remarkable biological properties of proteins is an important endeavor with both fundamental and practical implications. Recently, a number of nonnatural peptides with designed sequences have been elaborated to provide biologically active structures; in particular, facially amphiphilic peptides built from β-amino acids have been shown to mimic both the structures as well as the biological function of natural antimicrobial peptides such as magainins and cecropins. However, these natural peptides as well as their β-peptide analogues are expensive to prepare and difficult to produce on a large scale, limiting their …

Spsj 50th Annual Meeting, Osaka, Japan, May 23-25, 2001, Otto Vogl, Yasuhiko Shirota, Tatsuro Ouchi

Otto Vogl

No abstract provided.

On Characterizing Bgp Routing Table Growth, T Bu, Lx Gao, D Towsley

Lixin Gao

No abstract provided.

Assessing Student Learning In The Responsible Conduct Of Research, Kenneth D. Pimple

Ethics in Science and Engineering National Clearinghouse

Introduction

As with all effective teaching, a key element in any unit designed to teach research ethics is assessment of student learning, whether the “unit” is a whole course, a brown bag lunch seminar, or a few sessions or segments of sections within a course. How can we know what our students learned, and whether they learned what we intended them to learn? How can we tell whether our instructional goals were met?

I am reminded of the Saturday Night Live skit in which a reporter asks President Carter, “Why are you building the B-1 Bomber?” To which Carter replies, …

Functional Profiling Of The Saccharomyces Cerevisiae Genome, Patrick Flaherty

Mathematics and Statistics Department Faculty Publication Series

Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype are often missed. We systematically constructed a nearly complete collection of gene-deletion mutants (96% of annotated open reading frames, or ORFs) of the yeast Saccharomyces cerevisiae. DNA sequences dubbed 'molecular bar codes' uniquely identify each strain, enabling their growth to be analysed in parallel and the fitness contribution of each gene to be quantitatively assessed by hybridization to high-density oligonucleotide arrays. We show that previously known and new genes are necessary for optimal growth …