Engineering Commons^™

Cartilage Engineering: Optimization Of Media For Chondrogenic Differentiation In Vitro, Evan Surma, Sherry L. Harbin, Hongji Zhang, Stacy Halum

The Summer Undergraduate Research Fellowship (SURF) Symposium

Lower back pain from intervertebral disc injury affects around 84% of the population at some point in their life, which at its worst may cause total immobilization. This pain can only be temporarily relieved by spinal fusion or intervertebral disc replacement; however, both of these cause loss of natural motion in patients by removing damaged fibrocartilage discs. While these techniques help mitigate pain briefly, no permanent solution exists currently to both relieve pain and preserve natural motion. My work may be a solution by eventually providing patient-specific implants that resemble native tissue in the regeneration process that could be absorbed …

Ball Pressure Correlations With Peak Impact Force And The Potential For Cumulative Mtbi When Heading A Soccer Ball, Nicolas Leiva, Daniel Y. Shyu, Josh Auger, Eric Nauman

The Summer Undergraduate Research Fellowship (SURF) Symposium

Soccer is a unique sport in which athletes use their heads as tools for gameplay, which may ultimately cause cumulative traumatic brain injuries. Due to rising popularity of soccer in the United States alongside the increased occurrence of CTE and mTBI in other contact sports, there is a growing concern over how to keep the repetitive forces caused by heading, as low as possible. Different variables that can affect the peak force felt when heading a soccer ball can be simulated and compared with in-game data, however, this has never been properly tested before. In the present study two size …

Modeling Of Ion/Target Interactions In Plasma Facing Components Of Fusion Reactor, Nicole Neto Godry Farias, Tatyana Sizyuk, Ahmed Hassanein

The Summer Undergraduate Research Fellowship (SURF) Symposium

Nuclear fusion is a promising source of clean energy that can be one of the key future suppliers of the world’s increasing power demand. One of today’s main challenges faced by scientists and engineers regarding nuclear reactors is to design plasma-facing components (PFCs) that can withstand extreme conditions of temperature, pressure, and ions/particles irradiation. Material evolution and damage of PFCs are strongly related to the bombardment and diffusion processes of ions resulting from fusion fuel, i.e., deuterium and tritium and reaction products, i.e., helium. However, work is still needed in order to understand fuel diffusion in the presence of helium …

Development Of A New Nanohub Simulation Tool: Coarse Graining Of Crystalline Nano-Cellulose., Kuo Tian, Mehdi Shishehbor, Pablo Zavattieri

The Summer Undergraduate Research Fellowship (SURF) Symposium

Crystalline Nano-cellulose (CNC) is a general molecular structure obtained from acid hydrolysis of native fiber. They are often very short (100 to 1000 manometers) and the mechanical properties of CNC varies depend on length scale. Due to defect formation of the structure, the mechanical properties of the material composed of such CNC may vary drastically. This study was to provide a numerical tool to integrate a few valid modules and to better understand the mechanical properties of CNC and the overall performance of the bio-inspired material composed of CNC. Our focus is mainly on two type of composite structure [1] …

Nanobubbles Provide Theranostic Relief To Cancer Hypoxia, Christopher M. Long, Pushpak N. Bhandari, Joseph Irudayaraj

The Summer Undergraduate Research Fellowship (SURF) Symposium

Hypoxia is a common motif among tumors, contributing to metastasis, angiogenesis, cellular epigenetic abnormality, and resistance to cancer therapy. Hypoxia also plays a pivotal role in oncological studies, where it can be used as a principal target for new anti-cancer therapeutic methods. Oxygen nanobubbles were designed in an effort to target the hypoxic tumor regions, thus interrupting the hypoxia-inducible factor-1α (HIF-1α) regulatory pathway and inhibiting tumor progression. At less than 100nm, oxygen nanobubbles act as a vehicle for site-specific oxygen delivery, while also serving as an ultrasound contrast agent for advanced imaging purposes. Through in vitro and in vivo studies, …

Comparative Life Cycle Assessment Of Direct And Indirect Solar Water Disinfection Processes In Developing Countries, Jason K. Hawes, Margaret M. Busse, Ernest R. Blatchley Iii

The Summer Undergraduate Research Fellowship (SURF) Symposium

In July 2010, the UN General Assembly recognized the universal human right to sufficient water for health and sanitation (UN…, 2010). The reliable disinfection of this water plays a critical role in public health (Carter and Miller, 2005), and this study investigates the use of four ultraviolet (UV) disinfection methods for use in international development and disaster relief. The study focuses on the life cycle impacts of four direct and indirect solar ultraviolet disinfection systems. Direct solar disinfection refers to exposure of water to solar radiation, while indirect solar disinfection collects solar energy and uses this to power a UV …

Effects Of Internal Egr On Modern Diesel Engines Internal Equipped With Vva At Idle, Erik R. Santini, Dheeraj B. Gosala, Gregory M. Shaver

The Summer Undergraduate Research Fellowship (SURF) Symposium

Vehicle emissions regulations are continuing to grow more challenging requiring near-zero levels of pollutant emissions. Nitric oxide (NOx) emissions are heavily regulated with the emission limit expected to become 1/10^th of its present limit by 2021. In order to meet the new regulations, improvements in both the engine and the exhaust aftertreatment system are required. Exhaust gas recirculation (EGR) is used to reduce the NOx produced by the engine while the aftertreatment system converts most of the engine-out emissions to safer gases before releasing them to the atmosphere. One of the main challenges with the aftertreatment system is that …

Lipid Detection In Pig Arteries Using Intravascular Photoacoustic Imaging, Jieying Mai, Yingchun Cao, Ayeeshik Kole, Michael Sturek, Ji-Xin Cheng

The Summer Undergraduate Research Fellowship (SURF) Symposium

Heart disease is the leading cause of death in the United States and worldwide. Each year over 370,000 people died from coronary artery disease in America. As the primary form of coronary artery disease, atherosclerosis behaves as lipid-rich plaque development inside an artery wall. Vulnerable plaques are those prone to rupture, which may result in thrombus or even death. Typical hallmarks of a vulnerable plaque include thin fibrous cap, a large lipid-rich necrotic core and inflammatory infiltrate. The identification and accurate detection of these lipid depositions in the arterial wall is crucial in the diagnosis of atherosclerosis. However, none of …

Atomistic Configuration Interaction Simulation Tool For Semiconductor Based Quantum Computing Devices, Jingbo Wu, Archana Tankasala, Jim Fonseca, Rajib Rahman, Gerhard Klimeck

The Summer Undergraduate Research Fellowship (SURF) Symposium

Solid-state devices are promising candidates for quantum computing applications due to obvious advantages in compatibility with semiconductor fabrication technologies and the extremely long coherent times of electron and nuclear spins in these devices. In such devices, electron interactions are crucial for single and two qubit gate operations. Thus it is essential to evaluate these electron-electron interactions accurately for precise qubit control. It is shown that Atomistic Configuration Interaction can be used to accurately determine electron-electron interactions in realistic semiconductor quantum computing devices. In this work, an online simulation tool on Atomistic Configuration Interaction has been implemented and published on nanoHUB.org, …

Fabrication And Evaluation Of Magnetic Micro Actuators For Implantable Self-Clearing Glaucoma Drainage Devices, Haritha Ramadorai, Hyunsu Park, Hyowon Lee

The Summer Undergraduate Research Fellowship (SURF) Symposium

According to the World Health Organization, glaucoma is the second leading cause of blindness in the world. It currently affects more than 2.7 million people in the United States alone and over 79.6 million people worldwide are estimated to be inflicted by this debilitating disease by 2020. Glaucoma patients are often characterized with elevated intraocular pressure (IOP) and are treated with implantation of glaucoma drainage devices (GDD) to maintain optimum IOP. Although initially effective at delaying glaucoma progression, contemporary GDD often lead to numerous complications and only 50% of implanted devices remain functional after 5 years. Biofouling is seen to …

Effect Of Particle Concentration And Ac Electric Field Strength On Particle Trapping In Rapid Electrokinetic Patterning (Rep), Sixuan Li, Avanish Mishra, Steve Wereley

The Summer Undergraduate Research Fellowship (SURF) Symposium

Rapid Electrokinetic Patterning (REP) is an optoelectric technique for trapping and translating micro- and nanoparticles non-invasively. It uses a combination of laser-induced AC electrothermal flow and particle-electrode interactions in the presence of a uniform AC electric field. The trapping is governed by laser power, electric field strength, AC frequency and dielectric properties of the particle and the medium. A REP trap has an AC frequency, termed critical frequency, above which particles cannot be trapped. It is expected to be dependent on dielectric properties of the particle and the medium. However, we propose that the particle concentration and AC field strength …

Energy Transfer In Cdse Nanoplatelet Superlattices, Kelly Wang, Jordan Snaider, Libai Huang

The Summer Undergraduate Research Fellowship (SURF) Symposium

Two-dimension CdSe semiconductor nanoplatelets (NPLs) exhibit unique, highly desirable optical and electronic properties, such as large absorption crossection and bright emission. Fӧrster resonance energy transfer (FRET) between NPLs is responsible for the utility of these NPLs in fields such as lasing, lighting, solar energy, and sensing. Here we study energy transfer processes in NPL superlattices using photoluminescence (PL) and time resolved PL (TRPL) spectroscopic methods. Information on the effect of thickness of NPL is obtained through correlating PL and TRPL spectra of CdSe superlattices with AFM measurements. PL spectrum showed narrow fluorescence and absorption peaks at room temperature corresponding to …

Study Of Oxidative-Crosslink Reaction In Polyphenyl Sulfide (Pps) / Carbon Fiber And Its Influence In Additive Manufacturing, Dong Hee Kim, Eduardo Barocio, Bastian Brenken, Anthony Favaloro, Byron Pipes

The Summer Undergraduate Research Fellowship (SURF) Symposium

Ever since its development in 1980s, Fused Filament Fabrication (FFF) has been an attractive additive manufacturing technology due to its flexibility to create intricate shapes at lower costs and faster manufacturing process than subtractive techniques. These advantages make FFF suitable for printing molds for use in traditional composites manufacturing processes. Combining FFF with high-temperature thermoplastic composites enables producing molds that not only sustain autoclave conditions but also have low coefficient of thermal expansion (CTE). A semi-crystalline polymer, Poly-phenylene Sulfide (PPS), with 50% by weight of carbon fiber is used as feedstock material for FFF. Nonetheless, PPS is sensitive to undergo …

A Compact System For Photon Counting Based On Silicon Photomultiplier, Youngwoo Cho, Youngkee Jung, Euiwon Bae

The Summer Undergraduate Research Fellowship (SURF) Symposium

A compact and portable detection system is necessary to measure the amount of pollutant from environmental sample by detecting and quantifying the light emitted by bioluminescent reporters. This silicon photomultiplier based project is hoping to acquire even more accurate data at a far lower light level than previously developed smartphone based system. After pre-amplification and comparator, the signal is separated from the internal noise present in the overall circuit. Next, the microcontroller counts the number of pulses generated by the comparator in a set amount of time and transfers the data to the Bluetooth module for the smartphone to receive …

Photonicstd-2d: Modeling Light Scattering In Periodic Multilayer Photonic Structures, Alexey Bondarev, Shaimaa Azzam, Zhaxylyk Kudyshev, Alexander V. Kildishev

The Summer Undergraduate Research Fellowship (SURF) Symposium

Efficient modeling of electromagnetic processes in optical and plasmonic metamaterials is important for enabling new and exciting ways to manipulate light for advanced applications. In this work, we put together a tool for numerical simulation of propagation of normally incident light through a nanostructured multilayer composite material. The user builds a unit cell of a given material layer-by-layer starting from a substrate up to a superstrate, splitting each layer further into segments. The segments are defined by width and material -- dielectric, metal or active medium. Simulations are performed with the finite difference time domain (FDTD) method. A database of …

Design Optimization Of A Stochastic Multi-Objective Problem: Gaussian Process Regressions For Objective Surrogates, Juan Sebastian Martinez, Piyush Pandita, Rohit K. Tripathy, Ilias Bilionis

The Summer Undergraduate Research Fellowship (SURF) Symposium

Multi-objective optimization (MOO) problems arise frequently in science and engineering situations. In an optimization problem, we want to find the set of input parameters that generate the set of optimal outputs, mathematically known as the Pareto frontier (PF). Solving the MOO problem is a challenge since expensive experiments can be performed only a constrained number of times and there is a limited set of data to work with, e.g. a roll-to-roll microwave plasma chemical vapor deposition (MPCVD) reactor for manufacturing high quality graphene. State-of-the-art techniques, e.g. evolutionary algorithms; particle swarm optimization, require a large amount of observations and do not …

Decelerating I/O Power Management, Shuang Zhai, Felix Xiaozhu Lin

The Summer Undergraduate Research Fellowship (SURF) Symposium

System suspend/resume is crucial to energy proportionality of modern computers, from wearable to cloud servers. Ironically, this OS mechanism itself is slow and energy hungry. Through characterizing the Linux kernel on a variety of modern system-on-chips (SoCs), we show the major reason as slow power state transitions of IO, which keeps CPU waiting. Furthermore, we argue that the IO wait can hardly be reduced to a satisfactory level, because most of slow transitions of IO are bounded by peripherals, low-speed buses, or physical factors. Therefore, the kernel execution for suspend/resume should be offloaded to a miniature core that waits more …

Dna Bound Avicel Network: The Beginnings Of A Self-Healing Material, Emily R. Coleman, Michael R. Ladisch, Eduardo Ximenes, Marissa Karp, Kathleen Howell, Seockmo Ku, Nathan Mosier, Iman Beheshti Tabar

The Summer Undergraduate Research Fellowship (SURF) Symposium

Self-healing materials could potentially provide many improvements to engineering projects, including reduced maintenance and cost, and increased lifespan. It is desired to create a self-healing material proof of concept, which can then be altered for eventual application to the surfaces of small satellites with the goal of increasing material lifetimes. The intrinsic properties and abilities of DNA base pairing will be studied as a first test of proof of concept. The exploratory research reported in this short communication utilizes oxidation of small (50µm) particles of Avicel using TEMPO, followed by activation of Avicel particles via an EDC (1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride) …

Hydrophobic Zeolites For Applications In Adsorption And Catalysis, Zige Huang, Michael Cordon, Rajamani Gounder

The Summer Undergraduate Research Fellowship (SURF) Symposium

Lewis acidic zeolites such as Sn-Beta are commonly studied for use as selective catalysts for glucose isomerization to fructose in liquid water. Glucose to fructose isomerization is a critical reaction for lignocellulosic biomass upgrading, which converts abundant and renewable feedstocks into commercially desirable fuels and chemicals.

Industrial applications require catalysts that maintain optimal reactivity over long time scales, yet at typical reaction temperatures, Lewis acidic Beta zeolites are known to deactivate in liquid water through poorly understood mechanisms. Recent work in our group has shown that interactions between water and Sn-Beta zeolites can cause leaching of active Sn sites from …

Evaluation Of Strain Distortion Correction Protocol Using Scanning Electron Microscopy And Digital Image Correlation, Alexandra Mallory, Alberto Mello, Michael Sangid

The Summer Undergraduate Research Fellowship (SURF) Symposium

Scanning electron microscopy in combination with digital image correlation (SEM-DIC) is a useful technique for measuring strain in materials at the micro-scale. In particular, it can be used to identify micro-scale strain localizations that are the precursor to material failure. While SEM produces high resolution images of the microstructure, the images also contain a large amount of distortion that, during DIC, will result in distorted strain values that require correction. In this project, a nickel-based alloy underwent cyclic mechanical fatigue at three different high temperatures to a targeted maximum strain. Scanning electron microscopy imaging was done on a 200x150μm area …

Performance Of Tf-Vls Grown Inp Photovoltaic Cells, Junyan Shi, Yubo Sun, Peter Bermel

The Summer Undergraduate Research Fellowship (SURF) Symposium

A grand challenge of photovoltaics (PV) is to find materials offering a promising combination of low costs and high efficiencies. While III-V material-based PV cells have set many world records, often their cost is much greater than other commercial cells. To help address this gap, thin-film vapor-liquid-solid (TF-VLS) grown Indium Phosphide (InP) PV cells have recently been developed, which both eliminate a key source of high costs and offer a direct bandgap of 1.34eV with potential to approach maximum theoretical efficiencies. However, the unanticipated phenomenon of open circuit voltage (V_oc) degradation has prevented TF-VLS grown InP PV cells …

Mechanical Investigation Of Phase-Transforming Cellular And Origami Materials, John M. Cleveland, David Restrepo, Yunlan Zhang, Pablo Zavattieri, Nilesh Mankame

The Summer Undergraduate Research Fellowship (SURF) Symposium

Cellular materials, such as honeycombs and metallic foams, have attracted much attention due to their exceptional ability to absorb and diffuse mechanical energy. These materials have a wide range of applications, such as improving vehicle crash safety and helmet impact resistance. However, many of these materials are rendered unusable after one application. Phase-transforming cellular materials (PXCMs) utilize a reversible bistable mechanism to facilitate energy absorption from one-dimensional impacts and loads. These mechanisms have the added benefit over other cell structures of reusability. In this study, various PXCM designs are discussed and examined to determine their energy absorption capabilities.

Three different …

Haptic Foot Feedback For Kicking Training In Virtual Reality, Hank Huang, Hong Tan

The Summer Undergraduate Research Fellowship (SURF) Symposium

As means to further supplement athletic performances increases, virtual reality is becoming helpful to sports in terms of cognitive training such as reaction, mentality, and game strategies. With the aid of haptic feedback, interaction with virtual objects increases by another dimension, in addition to the presence of visual and auditory feedback. This research presents an integrated system of a virtual reality environment, motion tracking system, and a haptic unit designed for the dorsal foot. The prototype simulates a scenario of virtual kicking and returns haptic response upon collision between the user’s foot and virtual object. The overall system was evaluated …

Metamodels Of Residual Stress Buildup For Machining Process Modeling, Stuart B. Mccrorie, Michael Sangid

The Summer Undergraduate Research Fellowship (SURF) Symposium

In the process of machining materials, stresses, called residual stresses, accumulate in the workpiece being machined that remain after the process is completed. These residual stresses can affect the properties of the material or cause part distortion, and it is important that they be calculated to prevent complications from arising due to the residual stresses. However, these calculations can be incredibly computationally intensive, and thus other methods are needed to predict the residual stresses in materials for quick decision-making during machining. By using metamodels - a method of representing data where few data points exist - we can achieve an …

Continuous Ligand-Assisted Elution Chromatography Applied To Separation Of Rare Earth Elements, Jeremy A. Weinstock, David M. Harvey, N.-H. Linda Wang

The Summer Undergraduate Research Fellowship (SURF) Symposium

Rare earth elements (REEs) are metals used to make many valuable products such as magnets and electronics. Following their extraction from larger materials, REEs are to be separated into their individual components as high purity is required for product manufacture. Purification is very difficult because most (15/17) of the REEs are lanthanides (Ln’s) and Ln ions have the same valence and similar atomic radii. The current industrial process for purifying REEs involves using toxic solvents to perform a series of liquid-liquid extractions. Ling and Wang (2015) proposed a ligand-assisted batch chromatography process to purify Ln’s. The latter approach is a …

Fluid Flow Thermometry Using Thermographic Phosphors, Gabriel J. Fenoglio, Humberto J. Detrinidad, Aman Satija, Alex D. Casey, Robert P. Lucht, Terrence R. Meyer

The Summer Undergraduate Research Fellowship (SURF) Symposium

Phosphor thermometry is a non-intrusive thermometry technique that allows for spatially and temporally resolved surface temperature measurements. The thermographic method has been employed in a number of applications that include combustion, sprays, and gas flows. In the current work, we investigate the implementation of thermographic phosphors in liquid flows, which is of interest in a wide range of applications in heat transfer, fluid mechanics, and thermal systems. Zinc oxide doped with Zinc (ZnO:Zn) was the phosphor employed for experimentation due to its high emission intensity and insolubility. In order to explore this application, the phosphor powder was uniformly dispersed in …

Pore Scale Transport Of Miscible And Immiscible Fluids In Porous Media, Tolulope O. Odimayomi, Arezoo M. Ardekani

The Summer Undergraduate Research Fellowship (SURF) Symposium

The separation of harmful or valuable substances entrapped in porous media has applications in processes such as enhanced oil recovery, diffusion in tissue, and aquifer remediation. In this study the motion and removal rate of immiscible and miscible solutions have been analyzed to gain understanding of solvent effectiveness as it is diluted due to diffusion or mixing within porous materials. The extraction of oil using water, a surfactant solution of 4% CTAB in water, and a foam produced form the surfactant solution is observed using two dimensional flows between parallel slides containing cylindrical obstacles. The fluid motion is visualized. The …

Development Of Micro-/Nano-Architectures For Intracellular Sensing Platform, Ryan M. Preston, Dae Seung Wie, Chi Hwan Lee

The Summer Undergraduate Research Fellowship (SURF) Symposium

Currently available nanotechnologies are capable of creating various nanostructures in controlled dimensions such as particles (0D), wires (1D), membranes (2D), and cubes (3D) by exploiting “top-down” or “bottom-up” methods. However, there exist limitations to systematically construct hierarchical nanostructures with geometric complexities. This study is focused on developing a novel nanofabrication strategy that can rationally produce a set of hierarchical nanostructures configured with precisely engineered facets, tip shapes, and tectonic motifs. We aim to identify a collection of optimal materials, array layouts, basic components, and nanofabrication techniques for the production of hierarchical nanostructures by exploiting device-grade semiconducting silicon materials. To accomplish …

Brain Inspired Enhanced Learning Mechanism Based On Spike Timing Dependent Plasticity (Stdp) For Efficient Pattern Recognition In Spiking Neural Networks, Sourjya Roy, Gopalakrishnan Srinivasan, Vijay Raghunathan

The Summer Undergraduate Research Fellowship (SURF) Symposium

Artificial neural networks, that try to mimic the brain, are a very active area of research today. Such networks can potentially solve difficult problems such as image recognition, video analytics, lot more energy efficiently than when implemented in standard von-Neumann computing machines. New algorithms for neural computing with high bio-fidelity are being developed today to solve hard machine learning problems. In this work, we used a spiking network model, and implemented a self-learning technique using a Spike Timing Dependent Plasticity (STDP) algorithm, that closely mimics the neural activity of the brain. The basic STDP algorithm modulates the synaptic weights interconnecting …

Investigation Of Aluminum Foams And Graphite Fillers For Improving The Thermal Conductivity Of Paraffin Wax-Based Phase Change Materials, Javieradrian Ruiz, Amy Marconnet, Yash Ganatra, John Howarter, Alex Bruce

The Summer Undergraduate Research Fellowship (SURF) Symposium

Passive thermal management with phase change materials (PCMs) has become the one of the most promising methods to cool cell phone processors due to the relatively simple implementation and profound impact on processor temperatures. Enhancing the thermal properties of conventional PCMs, mainly thermal conductivity and latent heat storage, allows for an overall improved thermal management system. This study aims to improve the thermal conductivity of paraffin wax (a typical commercial PCM) by the introduction of an expanded graphite (EG) filler to form a paraffin wax composite, and then infiltration of the EG/paraffin composite into an aluminum foam matrix. The thermal …