Engineering Commons^™

Annealing Of Encapsulated Heavy Metals From Brine Water Utilizing Microwave Enabled Sol-Gel Process, Adam Michael Flynn

Electronic Theses and Dissertations

Various waste encapsulation strategies have been investigated to solidify and stabilize heavy metal wastewater for proper long-term storage. This work aims to enhance a method of novel sol-gel encapsulation of heavy metals from mock brine waters using tetramethyl orthosilicate with the addition of an annealing step at various temperatures in order to reduce leaching of metals from the silica monoliths when exposed to water. The metals tested for encapsulation and leaching were mercury (II) chloride, potassium dichromate, sodium selenite, boric acid, cadmium chloride, and copper (II) acetate. The annealing of the silica monoliths led to an increased degree of for …

Image Analysis Of Colloidal Systems For Pair And Triplet Correlations., Brianna Price

Electronic Theses and Dissertations

Interactions among colloidal particles drive stability of suspensions or the assembly of particles into larger superstructures such as agglomerates or crystals. Typically, colloidal interactions are modeled using pairwise interaction potential energies which consider the interactions between pairs of particles. However, additional particles can modulate pair potentials, leading models to predict incorrect behavior. To analyze the effects of three-body interactions on the structuring of colloidal systems, pair and triplet correlation functions are calculated from published experimental data. These correlation functions are then translated into empirical pair and triplet potentials of mean force, which are then used to model systems more accurately …

The Use Of Nanoparticles And Electrospun Fibers For Intravaginal Delivery To Treat Viral And Bacterial Infections And Electrophysiological Measurements Of Synthetic Chloride Channels., Farnaz Minooei

Electronic Theses and Dissertations

Female reproductive viral and bacterial infections affect millions of women worldwide. Given the diversity and magnitude of these unmet reproductive health challenges, topical administration of antiretrovirals (ARVs) and antibiotics have emerged as promising approaches to maintain and restore reproductive health. However, currently available intravaginal dosage forms often suffer from low user adherence and the need for frequent, daily administration to achieve therapeutic effect. To address these challenges, the broad goal of this research was to focus on the development of new localized nanoparticle (NP) and electrospun fiber dosage forms to prolong the delivery and enhance the efficacy of active agents …

Aqueous Redox Flow Batteries With Boron Doped Diamond As An Electrode., Alex M. Bates

Electronic Theses and Dissertations

As the interest and implementation of renewable energy accelerates, so does that of grid energy storage. It is widely believed that a cost-effective energy storage technology will bring about the proliferation of renewable energy. Redox flow battery (RFB) technology represents a promising solution to cost-effective grid energy storage. Compared to other technologies, RFBs have a long lifetime, high efficiency, are non-flammable, significantly reduce cost, and separately scale power and energy. The separation of power and energy enables increased energy capacity by simply adding electrolyte volume. Of the challenges facing RFB technology, one readily apparent is the cost of the active …

Addition Of Fermentation Experiment To Unit Operations Laboratory, Jeremy T. Rone

Electronic Theses and Dissertations

With the growth of the distillery and brewery industries and the potential jobs created for chemical engineers, it is imperative to equip the chemical engineering graduates from the University of Louisville with knowledge of bioreaction kinetics and experience in performing calculations to solve for concentration profiles and reaction rates. To accomplish this, it is recommended to add a fermentation experiment to the Unit Operations Laboratory II course.

Four groups of students from the Spring 2020 Unit Operations Laboratory II course performed the fermentation experiment. They were able to successfully complete all lab requirements as well as analyze the results and …

Labview Improvements And Equipment Redesign Of Unit Operations Distillation Column, Madalyn S Wead

Electronic Theses and Dissertations

Unit Operations labs are important tools to provide hands-on learning with various chemical processes. The distillation lab experiment allows students to connect equations and definitions from textbooks to the physical processes of distillation as they occur. LabVIEW was the software development tool used to create a program to control the distillation column from startup to shutdown. Improvements were made to both the distillation process equipment and the LabVIEW code to create a more interactive lab experience, enhance students’ conceptual understanding of distillation, and prepare students for their future career as chemical engineers.

Equipment addressed included non-linear valves, malfunctioning temperature and …

Determination Of Selenite And Selenate In Wet Flue Gas Desulfurization Process Water Through Ic-Icp-Ms And Hg-Icp-Aes, Samuel Anthony Kelty

Electronic Theses and Dissertations

During coal-fired electric power production, coal bound elemental selenium is released into the gas phase and oxidized to selenite and selenate in the wet flue gas desulfurization (WFGD) unit. Selenite and selenate solubilize in the WFGD process water. A process water system at a coal fired power plant contributes to environmental regulation compliance by removing the selenium species from WFGD process water. A selenium speciation method was developed for the purpose of better monitoring the selenium species present in the “treated” process water and to aid the process water system in meeting compliance with the Environmental Protection Agency’s Effluent Limitation …

Non-Invasive Detection And Assessment Of Coronary Stenosis From Blood Mean Residence Times., Javad Hashemi

Electronic Theses and Dissertations

Coronary artery stenosis is an abnormal narrowing of a coronary artery caused by an atherosclerotic lesion that reduces lumen space. Fractional flow reserve (FFR) is the gold standard method to determine the severity of coronary stenosis based on the determination of rest and hyperemic pressure fields, but requires an invasive medical procedure. Normal FFR is 1.0 and FFR RT, to account for varying volume and flow rate of individual segments. Blood_RT was computed in 100 patients who had undergone the pressure-wire FFR procedure, and a threshold for Blood_RT was determined to assess the physiological significance of a stenosis, …

Stabilization Of Bimodal Colloidal Systems Via Nanoparticle Haloing In Microgravity., Luke Hawtrey

Electronic Theses and Dissertations

Colloidal suspensions typically contain a multi-phase system of solid particles suspended in a liquid medium. Colloids are widely used in industrial applications such as inks, paints, motor oils, foods, cosmetics, and many more. Colloidal systems are typically formed by the interaction of the attractive van der Waals forces and one or more repulsive forces. These repulsive forces include electrostatic repulsion, steric hindrance, and nanoparticle haloing. Nanoparticle Haloing (NPH) is a phenomenon discovered in 2001 as a viable method to stabilize colloidal systems of uncharged silica microparticles using highly charged zirconia nanoparticles. For this thesis the effects of NPH were tested …

A Kinetic And Thermodynamic Model Of Ethylene Dichloride Pyrolysis., Travis J Czechorski

Electronic Theses and Dissertations

Ethylene dichloride (EDC) is a precursor for the production of vinyl chloride (VCM) which is subsequently polymerized to form polyvinyl chloride (PVC). To convert EDC to VCM, EDC undergoes a pyrolysis process in the absence of oxygen at temperatures exceeding 500C. However, process yields are limited by the uncontrolled production of side-products that can degrade the quality of PVC and poison the reactor. Thus, tight process controls and costly separations guided by heuristics and plant operator experience are used to optimize EDC pyrolysis. To improve the process, I have programed a kinetic model of EDC pyrolysis based upon estimations of …

Purification Of Biomass Hydrolyzates For The Promotion Of Xylose Diester Formation, Laura Fernandez

Electronic Theses and Dissertations

The application of a novel xylose isolation procedure using phenyl boronic acid esterification has been limited to the hydrolyzates of low extractive biomasses like hardwoods and agricultural resides. Hydrolyzates with lower sugar and higher extractive concentrations, like softwoods, have not yielded xylose, or even xylose diester (XDE), the first intermediate product in the new process, under the same conditions. This research applied evaporation concentration, adsorbent separation and membrane filtration to these lower performing biomass hydrolyzates to maximize the yield of the XDE formation step of the new xylose extraction process. Lab-scale tests of these techniques were applied to pine hydrolyzate …

Fluid Flow Analysis Of Diluted Evaporating American Whiskey Droplets., Martin J. Brown Vi

Electronic Theses and Dissertations

The recent discovery of the unique structures, whiskey webs, formed when the evaporation of diluted American whiskey, has raised many questions as to the nature of the structures. Their formation process follows as such: (1) dilution of the whiskey to form nanoaggregates, (2) formation of a monolayer at the air-liquid interface, (3) chaotic ethanol evaporation caused monolayer collapse (via dynamic pressure), (4) bulk fluid evaporation caused monolayer collapse (via reduction of surface area), where the web-like structures reside on the surface, and finally, (5) web-like structures deposit on the substrate. The webs imaged via SEM had a striking resemblance to …

Capture And Release Gels For Optimized Storage (Cargos), Theodore S. Kalbfleisch Ii

Electronic Theses and Dissertations

Unassisted, the lifetime of many proteins outside their natural environment is very short. Scientists generally need to extract the sample, often in remote locations, and then transport, isolate, and store such biospecimens relatively far from the point of origin in order to study them. Currently, the most commonly used methods for storage of biospecimens are cryopreservation or refrigeration which, though effective, have their fair share of flaws. Cryopreservation and refrigeration-based storage of biospecimens requires a great deal of space and other resources to be effective. Furthermore, the hardware required for cold storage does not transport well. These factors make such …

Nanowire Based Adsorbents/Catalysts For Co2 Capture And Utilization., Apolo Nambo

Electronic Theses and Dissertations

Even today, the major energy source is fossil fuels, which release CO₂, a greenhouse gas that contributes to global warming. CO₂ capture, storage (CCS) and/or utilization (CCU) technologies are two routes to mitigate this problem. Sorbents are being investigated in either temperature swing or pressure swing absorption approaches for carbon capture from flue gases. Solid sorbent based technology is a promising one but suffers from slow kinetics, low capacity and need for high temperatures. Thus, new sorbent materials that can have good CO₂ sorption capacity, recyclability are sought. Similarly, one of the utilization approaches for CO …

Plasma-Assisted Liquid Phase Epitaxy Of Gallium Nitride Using Molten Gallium., Daniel Felipe Jaramillo-Cabanzo

Electronic Theses and Dissertations

Next generation semiconductor materials such as Gallium Nitride (GaN) and Silicon Carbide (SiC) are rapidly replacing Silicon (Si) for high power and high frequency applications due to Si’s inherent limitations. Despite the advantages of GaN over SiC, adoption of GaN has been hindered due to the lack of a cost-effective bulk production technique. Thus, the inability to precure native substrates requires GaN-based architectures to be heteroepitaxially synthesized on non-native substrates, such as sapphire and even SiC. This research seeks to develop a cost effective and scalable method to produce low defect, bulk GaN encouraging the adoption of GaN based devices …

Plasma Oxidation Of Liquid Precursors For Complex Metal Oxides., Babajide Patrick Ajayi

Electronic Theses and Dissertations

Clean energy production and storage are two of the most significant challenges in the 21^st century currently limited by the discovery and development of new and advanced materials. Complex oxides and alloys made using earth-abundant elements will play a crucial role in technology development moving forward, however, current preparation techniques are limited by their inability to produce complex oxides and alloys with precise composition control at fast timescales. A concept was proposed to produce mixed metal oxides with composition control through the oxidation of liquid precursors via plasma oxidation. It was hypothesized that the oxidation process can be completed …

Synthesis, Characterization, And Evaluation Of Metal Complexes With Cancer Selective Anti-Proliferative Effects And Hydrogen Evolution Catalytic Properties., Nicholas Vishnosky

Electronic Theses and Dissertations

Bis-thiosemicarbazones (BTSC) and their metal chelates have properties that are useful in several different scientific fields. These systems have already received attention in major fields of biology and engineering. Hydrogen evolution reaction (HER) catalysts need to be cheap and operate under minimal overpotentials with a long lifetime. The treatment of cancer requires, novel agents that have potent cytotoxic activity against cancer cells while displaying minimal side effects. In this dissertation the modular synthesis of these bis-thiosemicarbazone systems is utilized to regulate the redox chemistry for employment in the desired sector of chemistry. The ligand and metal chelates synthesized were characterized …

Experimental Investigation Of The Manufacture Of Tunable Graphene Oxide Filter Membranes Using Intense Pulse Light, Joshua H Kotter

Electronic Theses and Dissertations

Reduced graphene oxide is a thin, strong, and inexpensive material with a channel and pore structure that make it a promising candidate for a filtration material. Reduced graphene oxide has been produced and tested in the laboratory, but a lack of scalable manufacturing techniques have limited its commercial use.

This thesis has shown that graphene oxide can be rapidly manufactured with an industrially scalable flash reduction process. The flash reduction process uses 0.58 millisecond pulses from a xenon lamp to reduce the graphene oxide film in less than a minute. Results for partially reduced graphene oxide membranes tuned by the …

Low Temperature Desiccants In Atmospheric Water Generation., Sunil Gupta

Electronic Theses and Dissertations

Surging global water demand as well as changes to weather patterns and over exploitation of natural water sources, such as ground water, has made potable water a critical resource in many parts of the World already – one rapidly heading towards a crisis situation. Desalination has been adopted as a solution – this is however energy intensive and impractical for most of the developing countries - those most in need of water. A renewable source of energy is solar thermal and solar photovoltaic. A plentiful source of water is the humidity in the atmosphere. This research is to push the …

Characterization Of Microreactor And Analysis Of Carbonyl Compounds In Exhaled Breath., Qi Li

Electronic Theses and Dissertations

Analysis of trace volatile organic compounds at parts per billion (ppbv) to parts per trillion (pptv) level has become an important research frontier because of the applicability for environmental monitoring and noninvasive diagnosis of diseases. The methods of preconcentration for detection of trace aldehydes and ketones both in ambient air and human exhaled breath have increased considerably over the last decade. However, the majority of these methods are not efficient. In this dissertation, we have improved an innovative microreactor that is suitable for quantitative analysis of volatile carbonyl compounds (VOCs) in ambient air as well as in human exhaled breath. …

Addition Of Exothermic Reaction Scale-Up Lab To Unit Operations Curriculum., Lisa A Anderson

Electronic Theses and Dissertations

According to the Chemical Safety Board’s 2002 report entitled "Improving Reactive Hazard Management,” the CSB identified 167 serious accidents involving uncontrolled chemical reactions in the United States between 1980 and 2001 causing 108 deaths and hundreds of millions of dollars in property damage. Of the 167 accidents, 35% involved runaway reactions. One noteworthy incident from recent history is the fatal explosion that occurred at T2 Laboratories in Jacksonville, FL as a result of improper scale-up and an insufficient cooling design for the system.

One recommendation resulting from the CSB investigation of the incident was that the Accreditation Board for Engineering …

Comparing Stenotic Blood Flow In Three- And Two-Dimensional Arterial Renderings Using Computational Fluid Dynamics And Multiphase Mean Age Theory., Jacob S. Garza

Electronic Theses and Dissertations

Over one million invasive coronary angiography procedures are performed annually in patients who experience chest pain or are known to have coronary artery disease. The procedure is carried out to ascertain the degree of arterial blockage (stenosis) that hinders blood flow to the heart. A cardiologist performing the procedure determines the physiological degree of a stenosis by either visual estimation, which is routine practice, or by invasively measuring fractional flow reserve (FFR), which is the current gold standard that has been demonstrated to improve patient outcomes and temper the cost of healthcare. Nevertheless, FFR is performed in only 10–20% of …

Enhancing Performance Of Ionic Liquid Property Prediction With Molecular Dynamics., Trisha H. Patel

Electronic Theses and Dissertations

Molecular dynamics have been used to predict thermodynamic and transport properties of eight room-temperature ionic liquids. Simulation parameters including box size and van der Waals cutoffs were varied. The density, heat capacity, and self-diffusion coefficients of the ionic liquids were computed and compared to experimental data and to previously published simulations. Predicted properties were generally close to their experimentally observed values. It was determined that the prediction of ionic liquid properties via molecular dynamics simulations could be accelerated several-fold by using less stringent integration parameters and smaller simulation sizes. The properties of density and heat capacity did not change significantly …

Sum Frequency Generation Spectroscopy Of Simulated Protein Secondary Structures., Andrew J. Adams

Electronic Theses and Dissertations

Sum frequency generation (SFG) spectroscopy is an experimental technique for differentiating between various conformations and orientations of interfacial proteins. Combining a theoretical framework for SFG with molecular dynamics (MD) simulations provides a powerful tool for studying systems containing interfacial proteins with applications in cell transport, biofilms, and fermentation processes. Roeters’ method was used to calculate theoretical SFG responses for a variety of individual α-helix and β-sheet peptide secondary structures simulated using MD. Results show how the shape and locations of SFG amide I responses change with differences in hydrogen bonding patterns, peptide orientations, and SFG polarization combinations. The data presented …

Artificial Olfactory System For Multi-Component Analysis Of Gas Mixtures., Alexander Aleksandrovich Larin

Electronic Theses and Dissertations

Gas analysis is an important part of our world and gas sensing technology is becoming more essential for various aspects of our life. A novel approach for gas mixture analysis by using portable gas chromatography in combination with an array of highly integrated and selective metal oxide (MOX) sensors has been studied. We developed a system with small size (7 x 13 x 16 inches), low power consumption (~10 W) and absence of special carrier gases designed for portable field analysis (assuming apriori calibration). Low ppb and even sub-ppb level of detection for some VOCs was achieved during the analysis …

A Comparison Of Mean Age Theory And Residence Time Distributions In Mixed Systems., Nolan Theaker

Electronic Theses and Dissertations

A comparison between mean age theory and conventional residence time distributions over a range of quantified mixing levels was conducted using computational fluid dynamics (CFD). The system was a stirred tubular reactor. The model was validated by comparing computationally derived RTD curves with experimentally obtained RTD curves, with quantified differences less than 3%. Mixing was quantified using the Tanks-in-Series model. Mixing levels were set by varying flow rate and impeller rpm. Mean age distributions at the outlet, where experimental RTD’s were measured, were very narrow for all levels of mixing studied. RTD’s showed expected characteristics; a wider distribution and long …

Novel Processing Approaches For Thin Film Solar And Related Technologies., Brandon Lavery

Electronic Theses and Dissertations

A growing population along with developing nations are increasing the demand for energy. The International Energy Agency forecasts a global electricity demand increase of 70 percent by 2040. This is an increase from nearly 18 TW to over 30 TW. The sun can be a great clean source of achieving this energy demand. Despite the large solar industry development, the market is still growing as solar energy only accounted for 0.87% of the global energy production in 2013. The opportunity exists to manufacture more affordable solar energy that can penetrate more of the global energy market. In this dissertation, a …

Novel Iii-V Alloys For Unassisted Water Splitting., Alejandro Martinez-Garcia

Electronic Theses and Dissertations

Direct conversion of solar energy to fuels by photoelectrochemical (PEC) water splitting has been identified as a promising route for sustainable power generation and storage. However, semiconductor materials with suitable opto-electronic properties have yet to be identified. In this dissertation, band gap engineering of III-V alloys, tuning the light sensitivity of GaP and GaN nitride through alloying Sb, is investigated for developing new semiconductor alloys with appropriate opto-electronic properties and their performance with overall water photoelectrolysis. In addition to III-V materials, copper oxide (Cu₂O) electrode was investigated for p-type semiconductor material. The new III-V alloy anodes were studied …

Effect Of High Cationic Flocculant On Anaerobic Digestion Of Municipal Wastewater., Prathap D. John

Electronic Theses and Dissertations

Anaerobic digestion (AD) of municipal sludge is a widely used stabilization process at municipal wastewater treatment plants. It is highly effective in reducing sludge volume and produces methane gas which is used as fuel in the wastewater plant. Following digestion sludge is sent to a centrifuge to separate the solids from the liquids. Louisville MSD adds flocculent to material in the centrifuge to better coagulate the solids, thereby aiding in separation of the solids from the liquids. The potential for further AD, COD reduction, and methane generation of the liquid effluent from the centrifuge was unknown, particularly in regards to …

Data Driven Discovery Of Materials Properties., Fadoua Khmaissia

Electronic Theses and Dissertations

The high pace of nowadays industrial evolution is creating an urgent need to design new cost efficient materials that can satisfy both current and future demands. However, with the increase of structural and functional complexity of materials, the ability to rationally design new materials with a precise set of properties has become increasingly challenging. This basic observation has triggered the idea of applying machine learning techniques in the field, which was further encouraged by the launch of the Materials Genome Initiative (MGI) by the US government since 2011. In this work, we present a novel approach to apply machine learning …