Engineering Commons^™

Process Variation-Aware Timing Optimization With Load Balance Of Multiple Paths In Dynamic And Mixed-Static-Dynamic Cmos Logic, Kumar Yelamarthi

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The semiconductor technology has been advancing rapidly over the past decade to result in the design of several innovative applications. This advancement of technology with the shrinking device has allowed for placement of billions of transistor on a single microprocessor chip. On the other hand, this shrinking device sizes has presented the design engineers with two major challenges: timing optimization at multiple giga-hertz frequencies, and reducing the daunting effects of semiconductor process variations. Failure to account for these process variations often results in loss of design productivity by one generation, and might even result in design failure.

This research presents …

Algorithmic Techniques Employed In The Isolation Of Codon Usage Biases In Prokaryotic Genomes, Douglas W. Raiford Iii

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While genomic sequencing projects are an abundant source of information for biological studies ranging from the molecular to the ecological in scale, much of the information present may yet be hidden from casual analysis. One such information domain, trends in codon usage, can provide a wealth of information about an organism's genes and their expression. Degeneracy in the genetic code allows more than one triplet codon to code for the same amino acid, and usage of these codons is often biased such that one or more of these synonymous codons is preferred. Isolation of translational efficiency bias can have important …

Composite Membranes For Proton Exchange Membrane Fuel Cells, Jinjun Shi

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Proton exchange membrane fuel cells (PEMFCs), often regarded as a green energy source, have become a promising candidate to replace traditional power sources. One of the obstacles toward commercialization of PEM fuel cells is lack of high performance and low cost proton exchange membranes. The objective of this study was to develop and evaluate higher-performance, Nafion-based composite proton exchange membranes that are suitable for operating at higher temperatures (> 85°C).

Proton exchange membranes were prepared by adding silica and heteropolyacids (HPAs) to a proton-conducting polymer matrix, Nafion. The added silica powder particles, either by direct mixing or sol-gel reaction, were …

System Design Of Undersea Vehicles With Multiple Sources Of Uncertainty, Todd W. Benanzer

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The work performed investigates the system design and optimization of an undersea vehicle. The system design is driven by the available components, the missions the vehicle is required to perform, and the performance the system configuration yields. The system design consists of three design modules: path planning, component selection and sizing, and structural analysis. The path planning module uses a novel application of the Particle Swarm Optimization algorithm named Path Planning by Additive Freedom. Additionally, the unknown aspects of the mission space through which the path propagates are dealt with using an uncertainty quantification method known as Evidence Theory. Component …

Intelligent Spectrum Sensor Radio, Omer Mian

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A cognitive radio is a radio with built-in intelligence that makes it able to utilize the radio frequency spectrum more efficiently by adapting to the changing conditions and frequency availability. In this thesis a spectrum sensor radio is designed that detects transmissions in FM band and determine the range of used and unused frequencies within the band. The radio then starts a transmission on a frequency among the available frequencies. This intelligent radio system design is implemented using the Universal Software Radio Peripheral and GNU Radio with a program written in python that uses a number of GNU Radio modules …

The Effects Of Chronic Hypoxia And Substance P On The Chemosensitive Response Of Individual Nucleus Tractus Solitarius (Nts) Neurons From Adult Rats, Nicole L. Nichols

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The chemosensitive responses of individual nucleus tractus solitarius (NTS) neurons from neonatal rats have been extensively studied, but few studies have examined the chemosensitive responses of NTS neurons from adult rats. In addition, environmental conditions have been used to mimic respiratory diseases/disorders in rats to study how the cellular responses of individual neurons change to regulate breathing during pathological conditions. Lastly, it has been shown that substance P release increases in response to hypoxia from peripheral afferents that primarily terminate in the caudal NTS. We studied the effect of chronic hypoxia (CHx) and substance P on the response to hypercapnia …

Energy Efficient Image Video Sensor Networks, Paul Anthony Bender

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Image Video Sensor Networks are emerging applications for sensor network technologies. The relatively large size of the data collected by image video sensors presents new challenges for the sensor network in terms of energy consumption and channel capacity. We address each of these issues through the use of a high density network deployment utilizing some nodes as dedicated relay nodes.

A high density network allows network nodes to reduce their transmission power. This reduction in transmission power allows each node to conserve power and simultaneously increases the potential for spatially concurrent transmissions within the network, resulting in improved network throughputs. …

Design Of Pulse Output Direct Digital Synthesizer With An Analog Filter Bank, Aditya R. Pothuri

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Over the past two decades frequency synthesizer has progressed from a relatively crystal bank synthesizer to multi-loop phase locked loops. But in recent years direct digital synthesizers (DDS) have witnessed an increase in demand over their analog counterparts. The DDS offers a wide range of advantages over phase locked loops such as high frequency range, fast switching response, and sub-hertz frequency resolution. However, the conventional DDS suffers limitations due to its architecture involving digital-to-analog converter (DAC) and read-only-memory (ROM) with respect to high clock speeds.

The Pulse Output Direct Digital Synthesizer (PODDS) presented in this thesis eliminates the necessity for …

Gps Coarse Acquisition Using The Monobit Fft Algorithm In A Broadband Receiver, John Flynn

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The purpose of this research was to investigate the feasibility of using broadband electronic warfare (EW) receivers for Global Position System (GPS) tracking. These are pulse-oriented receivers, typically with input bandwidths of 1 Ghz or larger, and so by definition do not have the same characteristics and processing of continuous wave (CW) receivers like GPS devices, FM radios, etc. For example, the spectral output of the Fast Fourier Transform (FFT) used in broadband signal processing updates on the frequency of the FFT input sample size, versus a CW receiver which updates on a more continuous basis.

The foundation of this …

A Study Of Multi-Echelon Inventory Systems With Stochastic Capacity And Intermediate Product Demand, Suman Niranjan

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The research in this dissertation involves the study of several multi-echelon inventory systems with stochastic capacity and intermediate product demand. Specifically we analyze the behavior of the system which consists of several intermediate product demands. The analysis is primarily three fold i) developed update (relational) equations for all the multi-echelon inventory systems under several inventory allocation policies, ii) develop two simulation optimization approaches 1) OptQuest framework, and 2) IPA (Infinitesimal Perturbation Analysis) framework, used to minimize the total cost of the inventory systems that satisfy the desired customer service level, iii) obtain numerical results for all the multi-echelon inventory systems …

Transformation Of Object-Oriented Associations And Embedded References To Them, Sneha Swamy

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AFIT Wide Spectrum Object Modeling Environment (AWSOME) automatically generates executable code by applying transforms to the formal specifications developed from the domain knowledge. AWSOME uses the specification language called as AFIT Wide Spectrum Language (AWL). All the transforms developed for AWSOME depend on and manipulate Abstract Syntax Trees (ASTs) created by parsing the formal specifications of a model. The main idea is to speed the process of creating error free code, to aid reusability of code and also to make the maintenance changes to be consistent and correct. The AWSOME metamodel contains the structural (object) model, the functional (operations) model …

Evaluation Of Overlay/Underlay Waveform Via Sd-Smse Framework For Enhancing Spectrum Efficiency, Vasu D. Chakravarthy

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Recent studies have suggested that spectrum congestion is mainly due to the inefficient use of spectrum rather than its unavailability. Dynamic Spectrum Access (DSA) and Cognitive Radio (CR) are two terminologies which are used in the context of improved spectrum efficiency and usage. The DSA concept has been around for quite some time while the advent of CR has created a paradigm shift in wireless communications and instigated a change in FCC policy towards spectrum regulations. DSA can be broadly categorized as using a 1) Dynamic Exclusive Use Model, 2) Spectrum Commons or Open sharing model or 3) Hierarchical Access …

Design Of A Cmos Rf Front End Receiver In 0.18Μm Technology, Vishwas Kudur Sastry

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An RF front end receiver system refers to the analog down conversion stages of the wireless communication system. The Digital base-band signals cannot be transmitted directly through wireless channels due to the properties of electromagnetic waves. The baseband signals need to be converted to analog through a digital-to-analog converter (DAC), up converted to higher frequency using an up conversion mixer and then transmitted through the channel. The received signals are down converted to base band frequency and then converted to digital again using the analog to digital converter (ADC). The processes which the analog signal undergoes at the RF front …

Information Presentation On Mobile Device For Plant Operations, Raghavendra Rao Polakonda

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Process control and maintenance systems have been used in the petrochemical and refining industry for long time for improving operator performance and workforce efficiency. However, there is a need to integrate these systems with current technological innovations in a systematic and meaningful manner. Advances in mobile computing, sensor technologies, software algorithms, and computational methods provide the possibility for easy access to information anytime-anywhere. The issues associated with retrieving and reviewing this information directly affects the ability to make timely and quality decisions in high stakes environments like a petrochemical plant where time critical decisions are involved. This research investigates the …

A Gnu Radio Based Software-Defined Radar, Lee K. Patton

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GNU Radio is an open source software-defined radio project, and the Universal Software Radio Peripheral (USRP) is hardware designed specifically for use with GNU Radio. Together, these two technologies have been used to implement very sophisticated, yet low cost, software-defined radios. Since software-defined radio and software-defined radar are really one in the same technologies, it stands to reason that GNU Radio and the USRP could be utilized to form a low cost radar sensor. In this thesis, we discuss the design of a prototype software-defined radar, built using the open source GNU Radio and open specification USRP projects. The prototype …

An Initial Methodology For The Definition And Implementation Of Unmanned Aerial Vehicle Agent Behaviors, William Eric Marsh

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In many current agent-based modeling systems, it is difficult for a domain-expert user to define and implement agent behaviors without possessing extensive programming knowledge. MUAVES is an existing simulation environment that serves as a research testbed for examining command and control issues with unmanned aerial vehicle (UAV) systems containing many vehicle agents. In its previous form, defining agent behaviors required knowledge of the C# programming language that some MUAVES users did not have. This thesis presents a new methodology for the definition and implementation of UAV agent behaviors in MUAVES. The new methodology is based on diagramming an agent's controller …

Modeling And Simulation Of A Microturbine Generator To Be Coupled With A Molten Carbonate Fuel Cell For Distributed Generation, Karleine M. Justice

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Distributed generation is desired when the individual energy requirements ranging from 25-75 kW of office buildings, restaurants, hospitals and apartments can not be met by the current electric utility grid. Microturbine generators as stand alone power generation systems have been designed to meet these requirements. For power requirements up to 50 MW, hybrid fuel cell systems offer higher efficiency and lower levels of pollutant emissions with more advanced fuel energy savings than non-hybrid systems. The objective of this project is to develop a simulation of a microturbine generator as a stand alone power generation system to validate a microturbine generator …

Change Detection Methods For Hyperspectral Imagery, Karmon Marie Vongsy

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This thesis studies the detection of changes using hyperspectral images. Change Detection (CD) is the process of identifying and examining temporal and spectral changes in signals. Detection and analysis of change provide valuable information of possible transformations in a scene. Hyperspectral imaging (HSI) sensors are capable of collecting data at hundreds of narrow spectral bands. Such sensors provide high-resolution spatial and spectrally rich information that can be exploited for CD. This work develops and implements various CD algorithms for detection of changes using Hyperspectral images. The main objectives are to study and develop different HSI change detection algorithms. The explored …

Computational Methods For The Objective Review Of Forensic Dna Testing Results, Jason R. Gilder

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Since the advent of criminal investigations, investigators have sought a "gold standard" for the evaluation of forensic evidence. Currently, deoxyribonucleic acid (DNA) technology is the most reliable method of identification. Short Tandem Repeat (STR) DNA genotyping has the potential for impressive match statistics, but the methodology not infallible. The condition of an evidentiary sample and potential issues with the handling and testing of a sample can lead to significant issues with the interpretation of DNA testing results. Forensic DNA interpretation standards are determined by laboratory validation studies that often involve small sample sizes. This dissertation presents novel methodologies to address …

Development Of An Intelligent Autonomous Coffee Maker, Nicholas J. Vanderpool

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Using Intelligent Control Methodology Home coffee machines have improved over time with the addition of features such as self-activating timers and crude temperature controlled heating elements. However, home coffee brewer development has stagnated and has yet to achieve full automation status. Present coffee machines leave the user burdened with the mundane and messy task of preparing the coffee maker every time. Also, should the user decide to prepare less than an entire pot, he/she must estimate the correct amount of water and coffee to add. This can lead to a weak or strong brew, giving undesirable results. In order to …

Phase-Locked Piv Investigation Of The Effects Of The Blowing Ratio Of A Pulsed Vortex Generator Jet In A Low-Pressure Turbine, Nathan Michael Woods

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At very high altitudes the Reynolds number flow through the low pressure turbine section of the gas turbine engine can drop below 25,000. At these low Reynolds numbers the flow is laminar and extremely susceptible to separation which can lead to increased losses and reduced lift. Small jets of air injected through the suction surface of the airfoil, called Vortex Generator Jets (VGJs), have been shown successful in suppressing separation and maintaining attached flow. Pulsing of these jets has been shown to be as effective as steady jets while reducing the amount of mass flow needed. An experiment using Particle …

High Spurious-Free Dynamic Range Digital Wideband Receiver For Multiple Signal Detection And Tracking, Vivek Sarathy

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The advent of field-programmable gate array (FPGA) has provided an excellent platform to market prototyping of full receiver-on-chip designs in a short time. The design of multi-tone wideband receiver has always been a challenge because of the difficulty to detect weak signals in the presence of noise in the frequency spectrum and also the presence of general spurs generated by the receiver. In this research, architecture for a FPGA-based 2.56-GSPS digital wideband receiver with multi-tone signal detection and tracking is designed to demonstrate the capability of replacing more expensive analog components into their cheaper digital design counterparts. Novel hardware implementations …

Designing Computer Agents With Personality To Improve Human-Machine Collaboration In Complex Systems, Sasanka V. Prabhala

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The dynamic nature of complex systems and the overwhelming amount of data that must be handled by human operators requires the development of smart systems that augment human capabilities. For these systems human-agent collaboration is part of the system dynamic. Unfortunately the computer agent is not typically perceived by the human operator as a collaborative team member. This research addressed the key question of how to develop and evaluate computer agents with personality to enhance human-machine collaboration. To move towards this goal three research objectives were established: (1) develop agents with personality, (2) validate that humans perceive these agents as …

On Optimal Survivability Design In Wdm Optical Networks Under Scheduled Traffic Models, Tianjian Li

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Wavelength division multiplexing (WDM) optical networks are widely viewed as the most appropriate choice for future Internet backbone with the potential to fulfill the ever-growing demands for bandwidth. WDM divides the enormous bandwidth of an optical fiber into many non-overlapping wavelength channels, each of which may operate at the rate of 10 Gigabit per second or higher. A failure in a network such as a cable cut may result in a tremendous loss of data. Therefore, survivability is a very important issue in WDM optical networks. The objective of this dissertation is to address the survivability provisioning problem in WDM …

Implementation For A Coherent Keyword-Based Xml Query Language, Venkatakalyan Potturi

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Due to the increasing pervasiveness of data sets using the XML data format, numerous query languages have been proposed that exploit the structure inherent in XML. Many such query languages, supported by specialized XML search engines, are complex and not suitable for naive users. A simple keyword based query language is described which not only exploits the structure of XML documents to extract relevant fragments, but can also fall back on retrieval through plain text search. This thesis focuses on developing a prototype implementation for a Coherent Keyword Based XML Query Language. It analyzes the typical challenges posed by the …

Loss Of Hdmx Leads To Alterations In Gene Expression And Inhibition Of Cell Growth In Tumor Cells With Wild-Type P53, Katherine Ann Heminger

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Mutations in the p53 tumor suppressor gene are among the most prevalent molecular abnormalities in human cancer. While half of all human tumors possess p53 mutations, inactivation of wild-type p53 can also occur through a variety of mechanisms that do not involve p53 gene mutation or deletion. This dissertation focuses on human tumor cell lines harboring wild-type p53 protein and elevated levels of HdmX and/or Hdm2, two critical negative regulators of p53 function. My hypothesis is that loss of HdmX in tumor cells with wild-type p53 and over-expressed HdmX, will activate p53 and induce p53 target genes leading to growth …

An Evolutionary Programming Algorithm For Automatic Chromatogram Alignment, Bonnie Jo Schwartz

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Scientists use liquid chromatography/mass spectrometry (LC/MS) instruments to measure metabolic responses to external stimuli. The data from these instruments can be distorted due to changes in the testing environment. Automating the removal of distortions is crucial in processing the data. The purpose of this thesis is to develop an algorithm that will automate the process.

The data produced by the LC/MS instrument were treated as images and image registration techniques were applied. A polynomial transformation function was assumed. An evolutionary programming algorithm was used to determine the coefficients of the polynomial. The data was manipulated to determine the best registration …

Multilingual Articulatory Features For Speech Recognition, Brian M. Ore

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Articulatory features describe the way in which the speech organs are used when producing speech sounds. Research has shown that incorporating this information into speech recognizers can lead to an improvement in system performance. The majority of previous work, however, has been limited to detecting articulatory features in a single language. In this thesis, Gaussian Mixture Models (GMMs) and Multi-Layer Perceptrons (MLPs) were used to detect articulatory features in English, German, Spanish, and Japanese. The outputs of the detectors were used to form the feature set for a Hidden Markov Model (HMM)-based phoneme recognizer. The best overall detection and recognition …

Role-Based Access Control For The Open Grid Services Architecture - Data Access And Integration (Ogsa-Dai), Anil L. Pereira

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Grid has emerged recently as an integration infrastructure for the sharing and coordinated use of diverse resources in dynamic, distributed virtual organizations (VOs). A Data Grid is an architecture for the access, exchange, and sharing of data in the Grid environment. In this dissertation, role-based access control (RBAC) systems for heterogeneous data resources in Data Grid systems are proposed. The Open Grid Services Architecture - Data Access and Integration (OGSA-DAI) is a widely used framework for the integration of heterogeneous data resources in Grid systems.

However, in the OGSA-DAI system, access control causes substantial administration overhead for resource providers in …

Structural And Signaling Elements Important For The Efficient Degradation Of Bhmt Through Macroautophagy, Carol A. Mercer

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Healthy cells maintain a dynamic and responsive intracellular environment that is marked by the synthesis and degradation of proteins, complex macromolecules and organelles. Autophagy, literally "self-eating," is a mechanism that delivers cellular cargo to the lytic compartment for digestion. Defects in the regulation of autophagy have been implicated in pathologies such as cancer and neurodegenerative disease, making the study of its regulation compelling. However, few studies have looked at the regulation of mammalian autophagy as a function of a specific cargo protein. Previous studies had indicated that the metabolic enzyme betaine homocysteine methyltransferase (BHMT) is degraded through an autophagic mechanism. …