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Articles 1 - 3 of 3
Full-Text Articles in Engineering
Additively Manufactured Polymeric Surface-Based Lattice Structures For Vibration Attenuation, Imabin Kelvin Ekpelu
Additively Manufactured Polymeric Surface-Based Lattice Structures For Vibration Attenuation, Imabin Kelvin Ekpelu
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The focus of this study was to select triply periodic minimal surface (TPMS) structures made of 3D-printed polymers. The primary variables in this study were: TPMS shape, lattice volume ratio, and lattice material. Vibration absorption was characterized by damping ratio via transmissibility at the system’s natural frequency. The vibration testing was performed using an electro-dynamic shaker, a known mass, an input/control accelerometer, and an output/response accelerometer. The 3D-printed absorber/lattice was mounted to the shaker baseplate and a mass will be mounted on top of the absorber. One accelerometer will be mounted to the shaker baseplate and the other will be …
Friend Or Foe? The Role Of Transforming Growth Factor-Β (Tgfβ) Signaling In Calcineurin Inhibitor-Induced Renal Damage, Adaku Uwe
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With its incorporation into clinical practice in the early 1980s, the class of pharmacological agents known as calcineurin inhibitors (CNIs) quickly became the cornerstone of immunosuppressive therapy post-organ transplantation. However, its use is limited by irreversible kidney damage in the form of renal fibrosis. The molecular mechanism by which CNIs induce renal fibrosis remains to be better understood, and to date, there are no specific therapeutic strategies to mitigate this damage. This dilemma presents a critical need to explain mechanisms by which CNIs cause renal damage. Kidneys of patients on chronic CNI therapy show increased expression of the proinflammatory cytokine …
Icing Mitigation Via High-Pressure Membrane Dehumidification In An Aircraft Thermal Management, Danielle D. Hollon
Icing Mitigation Via High-Pressure Membrane Dehumidification In An Aircraft Thermal Management, Danielle D. Hollon
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Icing, or the formation of ice from water via freezing or water vapor via desublimation, is a phenomenon that commonly occurs within air cycle-based refrigeration systems and requires thermal control that limits system performance. In aircraft applications icing frequently occurs in the heat exchangers and turbine(s) that are part of the air cycle machine, the refrigeration unit of the environmental control system. Traditionally, water vapor is removed from an air cycle machine via condensing in a heat exchanger and subsequent high-pressure water separation. This approach is not capable of removing all of the vapor present at low altitude conditions, corresponding …