Engineering Commons^™

Hard, Soft And Off-The-Shelf Foot Orthoses And Their Effect On The Angle Of The Medial Longitudinal Arch: A Biplane Fluoroscopy Study, Megan E.R. Balsdon, Colin E. Dombroski, Kristen Bushey, Thomas Jenkyn

Mechanical and Materials Engineering Publications

Background: Foot orthoses have proven to be effective for conservative management of various pathologies. Pathologies of the lower limb can be caused by abnormal biomechanics such as abnormal foot structure and alignment, leading to inadequate support. Objectives: To compare biomechanical effects of different foot orthoses on the medial longitudinal arch (MLA) during dynamic gait using skeletal kinematics. Study Design: Prospective, cross-sectional study design. Methods: The MLA angle was measured for 12 participants among three groups: pes planus, pes cavus and normal arch. Five conditions were compared: three orthotic devices (hard custom foot orthosis (CFO), soft CFO, and off-the-shelf Barefoot Science©), …

Development Of In Situ Forming Hydrogels For Intra-Articular Drug Delivery, Andy Prince

Electronic Thesis and Dissertation Repository

Hydrogels are 3-dimensional crosslinked polymer networks that can absorb significant amounts of water. The physical properties associated with hydrogels affords them resemblance to biological tissues making them good candidates for biomedical applications. Many pharmaceuticals, specifically non-steroidal anti-inflammatory drugs (NSAIDs), have poor aqueous solubility, which limits their bioavailability and efficacy. People suffering from chronic osteoarthritis (OA) are required to frequently take large doses to mitigate pain, which can lead to serious side effects. Hydrogels are good strategies to deliver NSAIDs via articular injection because they can form solid gels in situ. This thesis describes the synthesis, formulation, mechanical testing, in …

Autonomous And Real Time Rock Image Classification Using Convolutional Neural Networks, Alexis David Pascual

Electronic Thesis and Dissertation Repository

Autonomous image recognition has numerous potential applications in the field of planetary science and geology. For instance, having the ability to classify images of rocks would allow geologists to have immediate feedback without having to bring back samples to the laboratory. Also, planetary rovers could classify rocks in remote places and even in other planets without needing human intervention. In 2017, Shu et. al. used a Support Vector Machine (SVM) classification algorithm to classify 9 different types of rock images using a with the image features extracted autonomously. Through this method, they achieved a test accuracy of 96.71%. Within the …

A Network Approach To Interdependent Infrastructure Resilience Assessment For Natural Hazards, Howard Tong

Electronic Thesis and Dissertation Repository

Natural disasters are increasingly costly to society as they disrupt basic infrastructure functions. Infrastructure managers face challenges from growing urbanization, climate change, and aging infrastructure. Infrastructure resilience is an emerging concept that has been suggested as a solution to this problem; however, it is not yet mature. This thesis proposes to extend an existing dynamic infrastructure resilience quantification methodology to include infrastructure growth capabilities while relaxing some of the original constraints. The methodology uses a complex networks approach to model infrastructure interdependencies that is applied to a case study in the City of Toronto using a newly developed web tool.

Dynamic Light Scattering Optical Coherence Tomography To Probe Motion Of Subcellular Scatterers., Nico J J Arezza, Marjan Razani, Michael C Kolios

Medical Biophysics Publications

Optical coherence tomography (OCT) is used to provide anatomical information of biological systems but can also provide functional information by characterizing the motion of intracellular structures. Dynamic light scattering OCT was performed on intact, control MCF-7 breast cancer cells and cells either treated with paclitaxel to induce apoptosis or deprived of nutrients to induce oncosis. Autocorrelations (ACs) of the temporal fluctuations of OCT intensity signals demonstrate a significant decrease in decorrelation time after 24 h in both the paclitaxel-treated and nutrient-deprived cell groups but no significant differences between the two groups. The acquired ACs were then used as input for …

Bouncing Dynamics Of A Class Of Mem/Nem Switching Systems, Mohamed Bognash

Electronic Thesis and Dissertation Repository

The aim of the present research is to understand the bouncing dynamic behavior of NEM/MEM switches in order to improve the switch performance and reliability. It is well known that the bouncing can dramatically degrade the switch performance and life; hence, in the present study, bouncing dynamics of a cantilever-based NME/MEM switch has been studied in detail. To this end, a model of a MEM switch that incorporates electrostatic force, squeeze film air damping force as well as asperity-based contact force has been proposed for an electrostatically actuated switch. An actuation force due to piezoelectric effects is further included in …

Heat Of Hydration Thermal Performance And Flexural Capacity Of Stainless-Steel Reinforced Concrete Sections, Mokhtar Khalifa

Electronic Thesis and Dissertation Repository

Stainless steel (SS) is increasingly used in the construction field due to its high strength and corrosion resistance. However, its coefficient of thermal expansion is different from that of concrete. This difference raises concerns about the potential for concrete cracking during the hydration process. To address this concern, a thermal-structural finite element model was developed to predict the stresses in SS reinforced concrete (RC) sections during the hydration process. Different curing regimes were taken into consideration. The analysis was performed in two stages. First, a transient thermal analysis was performed to determine the temperature distribution within the concrete section as …

Apply Dry Powder On Drug Loading And Enteric Coating Of Esomeprazole Magnesium Trihydrate Beads And Capsules, Xiaojing Ge

Electronic Thesis and Dissertation Repository

Esomeprazole magnesium tri-hydrate (EMT) is a proton pump inhibitor, used for the treatment of gastric and duodenum ulcers. It is currently the best choice for the treatment of acid-related diseases, but it is extremely unstable in gastric acid and sensitive to wet, heat, light. It also will react with the enteric coating material used in this study. So enteric coating and sub coating is needed.

This study offers a new approach, dry powder coating technology, to achieve drug loading and enteric coating of EMT beads and capsules. Dry powder coating, a new type of solvent-less coating technology, can address most …

Commercial Water Claims: City Of London Assessment Of Claims Made By London Residents, Jonathan Abbruzzese, Yousir Aldin, Christine Eagles, Karen Lemon, Alexander Watson

Community Engaged Learning Final Projects

The City of London has a mandate to provide its residents with high grade water and yet there have been complaints concerning the impurities, otherwise known as residuals, and the overall quality. This paper delves into the truth about the contents of the municipal water system and what the effects of its components are to the London populace. A public survey asked residents questions about their concerns and water drinking habits. The survey pointed to concerns about fluoride, residual chlorine and overall taste of water among others. Fluoride is known to reduce tooth decay (CDC, 2018) and any negative consequences …

Compressible And Choked Flows In Rotating Passages, Nolan J. Dyck, Anthony G. Straatman

Mechanical and Materials Engineering Publications

No abstract provided.

A Numerical Approach For Determining The Resistance Of Fine Mesh Filters, Anthony Sherratt, Christopher T. Degroot, Anthony G. Straatman, Domenico Santoro

Mechanical and Materials Engineering Publications

No abstract provided.

Deep Learning: Edge-Cloud Data Analytics For Iot, Katarina Grolinger, Ananda M. Ghosh

Electrical and Computer Engineering Publications

Sensors, wearables, mobile and other Internet of Thing (IoT) devices are becoming increasingly integrated in all aspects of our lives. They are capable of collecting massive quantities of data that are typically transmitted to the cloud for processing. However, this results in increased network traffic and latencies. Edge computing has a potential to remedy these challenges by moving computation physically closer to the network edge where data are generated. However, edge computing does not have sufficient resources for complex data analytics tasks. Consequently, this paper investigates merging cloud and edge computing for IoT data analytics and presents a deep learning-based …

Ultrasound Calibration For Unique 2.5d Conical Images, Hareem Nisar, John Moore, Natasha Alves, Germain Hwang, Terry Peters, Elvis Chen

Robarts Imaging Publications

Intracardiac echocardiography (ICE) systems are routinely used in percutaneous cardiac interventions for inter-ventional and surgical navigation. Conavi’s Foresight ICE is a new ICE system that uses a mechanically rotatingtransducer to generate a 2D conical surface image in 3D space, in contrast to the more typical side-firing phasedarray. When combined with magnetic tracking technology, this unique imaging geometry poses new calibrationchallenges and opportunities. Existing ultrasound calibration methods are designed for 2D planar images andcannot be trivially applied to unique 2.5D conical surface images provided by the Foresight ICE system. In thiswork a spatial and temporal calibration technique applied to the unique …

Ductile Corrosion-Free Self-Centering Concrete Elements, Maged Youssef, Mohamed E. Meshaly, Ahmed Elansary

Civil and Environmental Engineering Publications

Corrosion is a major factor in the deterioration of reinforced concrete (RC) structures. To mitigate this problem, steel bars can be replaced with glass-fiber-reinforced-polymer (GFRP) bars. However, the lack of ductility of GFRP-RC elements has prevented their use in many structural applications, especially in seismic areas. Superelastic shape memory alloy (SMA) bars have been proposed to be used in seismic areas because of their self-centering characteristics. Also, they have the added advantage of being corrosion resistant. This paper examines the combined use of SMA and GFRP bars to achieve ductile self-centering and corrosion-free elements. The first challenge for such a …

Flexural Behaviour Of Superelastic Shape Memory Alloy Reinforced Concrete Beams During Loading And Unloading Stages, Yamen Ibrahim Elbahy, Maged Youssef

Civil and Environmental Engineering Publications

Trend of using smart structures, which can adjust when exposed to severe unexpected loading, is increasing. One of the methods to achieve such structures relies on smart materials. For example, replacing conventional steel reinforcing bars in Reinforced Concrete (RC) structures with superelastic Shape Memory Alloy (SMA) bars significantly reduces the residual deformations caused by post-yielding behaviour. This paper provides in-depth understanding of the flexural behaviour of SMA RC beams. A sectional analysis method, which predicts the flexural behaviour of SMA RC beams during both loading and unloading stages, is adopted and validated using available experimental data. An extensive parametric study …

Seismic Performance Of Reinforced Concrete Frames Retrofitted Using External Superelastic Shape Memory Alloy Bars, Yamen Ibrahim Elbahy, Maged A. Youssef, Mohamed E. Meshaly

Civil and Environmental Engineering Publications

Pre-1970s designed and built reinforced concrete frame structures are considered unsafe when subjected to seismic loads. Insufficient anchorage of the beam reinforcement in the beam-column joints of these structures is considered a main deficiency. Newly built frame structures are seismically designed for safety, where high inelastic deformations can occur under moderate to strong earthquakes. Minimizing these inelastic deformations makes the structure repairable. One way to minimize these residual deformations is by using smart materials such as superelastic shape memory alloys (SMAs). In this paper, the seismic performance of RC frames retrofitted using external superelastic SMA bars is investigated and compared …

A Virtual-Reality Training Simulator For Cochlear Implant Surgery, Blake Jones, Seyed Alireza Rohani, Nelson Ong, Tarek Tayeh, Hanif M. Ladak, Ahmad Chalabi, Sumit K. Agrawal

Electrical and Computer Engineering Publications

No abstract provided.