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Full-Text Articles in Engineering

Numerical Study Of Flow Of Supercritical Carbon Dioxide Inside Microchannels With Heat Transfer, Uday Manda Jan 2022

Numerical Study Of Flow Of Supercritical Carbon Dioxide Inside Microchannels With Heat Transfer, Uday Manda

Electronic Theses and Dissertations, 2020-

Heat transfer inside microscale geometries is a complex and a challenging phenomenon. As supercritical fluids display large variations in their properties in the vicinity of the critical point, their usage could be more beneficial than traditional coolants. This numerical study, in two parts, primarily focuses on the physics that drives the enhanced heat transfer characteristics of carbon dioxide (CO2) near its critical state and in its supercritical state. In the first part of the study, the flow of supercritical Carbon Dioxide (sCO2) over a heated surface inside a microchannel of hydraulic diameter 0.3 mm was studied using three-dimensional computational fluid …


Modeling And Simulation Of A Power Plant Boiler Including The Dynamics Of Swell And Shrink, Richard Perman Jan 2022

Modeling And Simulation Of A Power Plant Boiler Including The Dynamics Of Swell And Shrink, Richard Perman

Electronic Theses and Dissertations, 2020-

Renewables such as photovoltaics and wind turbines have seen consistent growth in markets across the globe. While renewables increase grid capacity and reduce the use of fossil fuels, their generation rates fluctuate subject to external factors. As the ratio of renewables to nonrenewables increases, so does variability of net load on intermediate and peaking power plants. Power plants with heat recovery steam generators (HRSG) constitute a significant proportion in these categories. There are several interconnected systems within HRSGs, including drum boilers which exhibit interesting transient phenomena known as swell and shrink. Improved understanding, dynamic modeling, and real-time simulation (RTS) of …


Complex Quantum Contagion: A Quantum-Like Approach For The Analysis Of Co-Evolutionary Dynamics Of Social Contagion, Ece Mutlu Jan 2022

Complex Quantum Contagion: A Quantum-Like Approach For The Analysis Of Co-Evolutionary Dynamics Of Social Contagion, Ece Mutlu

Electronic Theses and Dissertations, 2020-

Modeling the dynamics of social contagion processes has recently attracted a substantial amount of interest from researchers due to its wide applicability in network science, multi-agent systems, information science, and marketing. Unlike in biological spreading, the existence of a reinforcement effect in social contagion necessitates considering the complexity of individuals in the systems. Although many studies acknowledged the heterogeneity of the individuals in their adoption of information (or behavior), there are no studies that take into account the individuals' uncertainty during their decision-making despite its theoretical and experimental evidence in behavioral economics, decision science, cognitive science, or multi-agent systems. This …


Search Space Reduction Techniques For Solution Of Combinatorial Optimization Problems In Power System., Ranadhir Sarkar Jan 2022

Search Space Reduction Techniques For Solution Of Combinatorial Optimization Problems In Power System., Ranadhir Sarkar

Electronic Theses and Dissertations, 2020-

Power system is vulnerable to disastrous climate events due to sequential or successive equipment failure. In this dissertation, the problem of identifying the critical k-transmission lines that fail one after another in quick succession, and the distribution system restoration problem using tie-lines/sectionalizing switches formulated as a mixed-integer non-linear programming problem (MINLP) that determines load shed under various k-line removal scenarios are solved. These problems are combinatorial that have huge search space, and solution through enumeration is intractable for large power systems. For reduction of search space, the following mathematical tools are derived, (i) two power flow methods due to k-transmission …


A Contingent Approach To Studying Technical Programs In The Public Aerospace Industry, Laura Segarra Jan 2022

A Contingent Approach To Studying Technical Programs In The Public Aerospace Industry, Laura Segarra

Electronic Theses and Dissertations, 2020-

Bibliometric evaluation of the literature indicates that a unified theory of program management does not yet exist. The vastly different definitions and implementations of programs across organizations and industries indicate that program management as an organizational concept is not well understood. As researchers have tried to make sense of various perspectives and definitions, it becomes clear that different kinds of programs exist, and further attention to their context is needed. While relationships between structural and environmental variables have been extensively researched in organizational studies, studies in program management are scant, lack incorporation of environmental variables relevant to programs and projects, …


Space-Time Photonics, Abbas Shiri Jan 2022

Space-Time Photonics, Abbas Shiri

Electronic Theses and Dissertations, 2020-

Many of the features of photonic devices, including some of the most ubiquitous components such as resonators and waveguides, are usually thought to be intrinsically dependent on their geometry and constitutive materials. As such, the behaviour of an optical field interacting with such devices is dictated by the boundary conditions imposed upon the field. For instance, the resonant wavelengths and linewidths of a planar cavity are expected to be set by the mirrors' reflectivity, cavity length, and refractive index. Henceforth, satisfying a longitudinal phase-matching condition allows for incident light to resonate with the cavity. As another example, consider the planar …


Mixed-Criticality System Design For Real-Time Scheduling And Routing Upon Platforms With Uncertainties, Sudharsan Vaidhun Bhaskar Jan 2022

Mixed-Criticality System Design For Real-Time Scheduling And Routing Upon Platforms With Uncertainties, Sudharsan Vaidhun Bhaskar

Electronic Theses and Dissertations, 2020-

Unlike typical computing systems, applications in real-time systems require strict timing guarantees. In the pursuit of providing guarantees, the complex dynamic behaviors of these systems are simplified using models to keep the analysis tractable. In order to guarantee safety, such models often involve pessimistic assumptions. While the amount of pessimism was reasonable for simple computing platforms, for modern platforms the pessimism involves ignoring features that improve performance such as cache usage, instruction pipelines, and more. In this work, we explore routing and scheduling problems in real-time systems, where the uncertainties in the operation are carefully accounted for by complex models …


Design And Mechanical Characterization Of Functionally Graded Sandwich Beams Fabricated Via Additive Manufacturing, Timothy Grondin Jan 2022

Design And Mechanical Characterization Of Functionally Graded Sandwich Beams Fabricated Via Additive Manufacturing, Timothy Grondin

Electronic Theses and Dissertations, 2020-

Lightweight aerospace structures have been sought after since humans took flight in 1903, making major strides in NASA's pursuit of the moon with the development of sandwich panel composites. Sandwich structures typically consist of two stiff phases (i.e., face sheets) separated by a lightweight phase (i.e., core), which are stacked together through adhesive layers. Such a structural arrangement provides a high stiffness-to-weight ratio and is often used in applications where weight saving is critical. Functionally Graded Materials (FGMs), refer to multifunctional materials, which contain a spatial variation of composition and/or microstructure for the specific purpose of altering thermal and structural …


Generative Modeling Of Human Behavior: Social Interaction And Networked Coordination In Shared Facilities, Saumya Gupta Jan 2022

Generative Modeling Of Human Behavior: Social Interaction And Networked Coordination In Shared Facilities, Saumya Gupta

Electronic Theses and Dissertations, 2020-

Urbanization is bringing together various modes of transport, and with that, there are challenges to maintaining the safety of all road users, especially vulnerable road users (VRUs). Therefore, there is a need for street designs that encourages cooperation and resource sharing among road users. Shared space is a street design approach that softens the demarcation of vehicles and pedestrian traffic by reducing traffic rules, traffic signals, road markings, and regulations. Understanding the interactions and trajectory formations of various VRUs will facilitate the design of safer shared spaces. It will also lead to many applications, such as implementing reliable ad hoc …


Air Force Pilot's Recognition About The Effectiveness Of Active Noise Cancellation On Hearing Health, Performance, And Aviation Safety, Kyungtaek Hwang Jan 2022

Air Force Pilot's Recognition About The Effectiveness Of Active Noise Cancellation On Hearing Health, Performance, And Aviation Safety, Kyungtaek Hwang

Electronic Theses and Dissertations, 2020-

The purpose of this thesis is to suggest the application of Active Noise Cancellation in Air Force pilot headset and helmet not only to reduce noise-induced hearing damage, but also to enhance pilot performance and aviation safety. Despite the recent advances of sound treatment technology, the interior sounds of a military aircraft exceed the damage risk criterion of 8 hrs/day exposure. Air Force pilots are flying under the extreme condition where noise is severe and prevalent. The exposure to noise can lead to permanent hearing loss, stress and fatigue, unintelligible communication, and deterioration of speech perception and recall. With all …


Flame-Generated Turbulence For Flame Acceleration And Detonation Transition, Rachel Hytovick Jan 2022

Flame-Generated Turbulence For Flame Acceleration And Detonation Transition, Rachel Hytovick

Electronic Theses and Dissertations, 2020-

Detonations are a supersonic mode of combustion witnessed in a variety of applications, from next-generation propulsion devices to catastrophic explosions and the formation of supernovas. Detonations are typically initiated through the deflagration to detonation transition (DDT), a detailed process where a subsonic flame undergoes rapid acceleration increasing compressibility until a hotspot forms on the flame front inciting a detonation wave to form. Due to the complex nature of the phenomena, DDT is commonly investigated in three stages – (i) preconditioning, (ii) detonation onset, and (iii) wave propagation and stability. The research presented explores each of these stages individually, with a …


Reconfigurable Load-Modulated Power Amplifier For Energy- And Spectrum-Efficient Wireless Communications, Haifeng Lyu Jan 2022

Reconfigurable Load-Modulated Power Amplifier For Energy- And Spectrum-Efficient Wireless Communications, Haifeng Lyu

Electronic Theses and Dissertations, 2020-

With the increasing demand for faster date rates and extensive user connectivities, the complex modulation schemes and large-scaled arrays have been widely researched and employed in the modern wireless links e.g., 5G and beyond-5G systems. These pose major challenges to design the power amplifiers (PAs) to accommodate the system level evolution. As the critical part, the power amplifiers (PAs) dominate the output power, efficiency, linearity and reliability of the radio frequency (RF) transmitter. Consequently, the PA's capability of maintaining an efficient, linear and reliable signal amplification operation is essential to the communication systems. On the other hand, due to the …


Electrode Evaluation And Electrocortical Dynamics Of Adapting To Small Perturbations During Treadmill Walking, Jinfeng Li Jan 2022

Electrode Evaluation And Electrocortical Dynamics Of Adapting To Small Perturbations During Treadmill Walking, Jinfeng Li

Electronic Theses and Dissertations, 2020-

Mobile brain-body imaging (MoBI) seeks to understand human brain and body dynamics during movement and locomotor tasks such as walking with perturbations that challenge balance and lead to adaptation of walking behavior. In this dissertation, I evaluated the long-term electromyography (EMG) recording performance of dry epidermal electrodes for measuring electrical muscle activity. I also evaluated the relationships between the signals recorded from the two sides of dual-sided electroencephalography (EEG) electrodes, a recent advancement in EEG electrode design for measuring electrical brain activity. Last, I investigated adaptation of brain and body responses to small and frequent perturbations during treadmill walking while …


A Study Of Autorotation: Samara Seed Pods And Tethered Autogyros, Jonathan Mcconnell Jan 2022

A Study Of Autorotation: Samara Seed Pods And Tethered Autogyros, Jonathan Mcconnell

Electronic Theses and Dissertations, 2020-

This work presents an exploration of autorotational behavior, observing naturally occurring structures to provide insight into the stability and design of autorotative mechanisms. A rotor is said to be in autorotation when, in the presence of airflow, a natural rotation generates lift to either suspend or slow the descent of a rotor. This phenomenon is observed in nature in the form of samaras, a seed pod morphology evolved in parallel by maple trees and many other organisms around the world. Simulation and experimental observation of samara vertical descent behavior provides insight into the stability of naturally evolved autorotative structures. A …


Investigating The Effect Of Cmas Infiltration On Residual Stress Of High Temperature Ceramic Coatings For Turbine Engines Using 3d Confocal Raman Spectroscopy, Zachary Stein Jan 2022

Investigating The Effect Of Cmas Infiltration On Residual Stress Of High Temperature Ceramic Coatings For Turbine Engines Using 3d Confocal Raman Spectroscopy, Zachary Stein

Electronic Theses and Dissertations, 2020-

Calcium-magnesium-aluminosilicates (CMAS), such as sand or volcanic ash, are ingested by aircraft jet engines during operation. CMAS then becomes molten while traveling through the combustor of the engine before depositing onto turbine blades within the turbine section of the engine. The molten CMAS melt infiltrates and interacts with the high temperature ceramic coated turbine blades. This infiltration increases coating stiffness and promotes coating phase destabilization, encouraging micro-crack formation and increasing the risk of spallation. Thermomechanical effects from CMAS infiltration were mapped over time with confocal Raman spectroscopy. The residual stresses within infiltrated 7YSZ EB-PVD coatings were captured with microscale resolution. …


Examining The Relationship Between Six Sigma Failures And The Utilization Of Cost Engineering Approaches, Dennis Tribby Jan 2022

Examining The Relationship Between Six Sigma Failures And The Utilization Of Cost Engineering Approaches, Dennis Tribby

Electronic Theses and Dissertations, 2020-

The purpose of the quantitative non-experimental research study is to analyze the relationship between the impact of using cost engineering approaches and the success rate of Six Sigma projects in the manufacturing industry. This study focuses on the relationship between Six Sigma project failures and whether skilled cost engineering professionals, methods or a cost management system was used to ensure that accurate cost data was utilized during the design project's lifecycle. Many companies using Six Sigma and related methodologies for product design have implemented with great success yet there are studies indicating that only 13% of firms reported achieving their …


Testing The Influence Of Water Depth In Design Of Created Oyster Reef For Living Shoreline Applications, Peter Vien Jan 2022

Testing The Influence Of Water Depth In Design Of Created Oyster Reef For Living Shoreline Applications, Peter Vien

Electronic Theses and Dissertations, 2020-

Living shoreline stabilization has become a popular practice in shoreline restoration and bank protection; however, there are still many uncertainties regarding effective site design using living materials. For example, natural wave-breaks may be formed of created reefs, but the optimum water depth for hydrodynamic influence may differ from the preferred depth to ensure organism recruitment. The objective of this research is to understand how water depth relative to the crest of submerged artificial oyster reef structures influences nearshore hydrodynamic processes and sediment transport or retention in nearshore areas. A field study, sited in a microtidal estuary on the Atlantic coast …


Detecting And Tracking Vulnerable Road Users' Trajectories Using Different Types Of Sensors Fusion, Zhongchuan Wang Jan 2022

Detecting And Tracking Vulnerable Road Users' Trajectories Using Different Types Of Sensors Fusion, Zhongchuan Wang

Electronic Theses and Dissertations, 2020-

Vulnerable road user (VRU) detection and tracking has been a key challenge in transportation research. Different types of sensors such as the camera, LiDAR, and inertial measurement units (IMUs) have been used for this purpose. For detection and tracking with the camera, it is necessary to perform calibration to obtain correct GPS trajectories. This method is often tedious and necessitates accurate ground truth data. Moreover, if the camera performs any pan-tilt-zoom function, it is usually necessary to recalibrate the camera. In this thesis, we propose camera calibration using an auxiliary sensor: ultra-wideband (UWB). USBs are capable of tracking a road …


A Deep Learning Approach For Spatiotemporal-Data-Driven Traffic State Estimation, Amr Hatem Ragaa Abdelraouf Jan 2022

A Deep Learning Approach For Spatiotemporal-Data-Driven Traffic State Estimation, Amr Hatem Ragaa Abdelraouf

Electronic Theses and Dissertations, 2020-

The past decade witnessed rapid developments in traffic data sensing technologies in the form of roadside detector hardware, vehicle on-board units, and pedestrian wearable devices. The growing magnitude and complexity of the available traffic data has fueled the demand for data-driven models that can handle large scale inputs. In the recent past, deep-learning-powered algorithms have become the state-of-the-art for various data-driven applications. In this research, three applications of deep learning algorithms for traffic state estimation were investigated. Firstly, network-wide traffic parameters estimation was explored. An attention-based multi-encoder-decoder (Att-MED) neural network architecture was proposed and trained to predict freeway traffic speed …


Characteristics Of Rotating Detonation Engines For Propulsion And Power Generation, Robert Burke Jan 2022

Characteristics Of Rotating Detonation Engines For Propulsion And Power Generation, Robert Burke

Electronic Theses and Dissertations, 2020-

Conventional engines are limited by the efficiency of their combustion mode. Compared to present constant pressure deflagration-based engines, detonation-based systems can realize a higher thermodynamic cycle efficiency, making them an attractive candidate for next generation propulsion systems that will take humanity to hypersonic speeds and even to Mars. For all its performance gains, detonation engines are still far off from implementation. One system, the rotating detonation engine (RDE) is promising as a detonation-based engine concept for its stability, simplicity, and versatility. For these reasons, RDEs have been the subject of studies internationally in efforts to understand their operation and integration …


Investigating The Effects Of Negative Influence Gradients And Emotion Contagion On The Information Processing Capacity Of Social Media Users: Information Diffusion Modeling Approach, Nisha Baral Jan 2022

Investigating The Effects Of Negative Influence Gradients And Emotion Contagion On The Information Processing Capacity Of Social Media Users: Information Diffusion Modeling Approach, Nisha Baral

Electronic Theses and Dissertations, 2020-

With the growing use of Online social media (OSM), users are observing a substantial amount of information in their social feeds. Moreover, people often use multiple OSM platforms because of each platform's unique features. Because of the huge volume of information present in social feeds, it restricts a user's ability to process the relevant information since the most important information may be overwhelmed by unimportant information. For information to diffuse in OSM, the receiver's attention is the most important condition. Cognition plays an important role in determining a user's attention/responsiveness. If OSM users receive the information above their cognition limits …


Fabrication Of Copper Nanoparticle/Graphene Oxide Composites And Reduction Of Copper Oxide Nanowires, Maged Elshatoury Jan 2022

Fabrication Of Copper Nanoparticle/Graphene Oxide Composites And Reduction Of Copper Oxide Nanowires, Maged Elshatoury

Electronic Theses and Dissertations, 2020-

The thesis reports the investigation of producing copper nanoparticle composites with graphene oxides (GO) using poly (sodium 4-styrenesulfonate) (PSS) and copper nanowires through the reduction of copper oxide nanowires using hydrazine. It was discovered that PSS improved the dispersity of GO and increased the absorption of copper ions on GO. An electrochemical reduction of GO/PSS/copper ion dispersion produced copper nanoparticles on GO surfaces. Reducing copper oxide nanowires on copper foils using hydrazine was achieved at a temperature where copper nanowires maintained their nanoscale structures.


Not All Influence Is Born Equal: On The Effects Of Various Types Of Behavioral Influence Relationships On Social Media, Chathurani Senevirathna Jan 2022

Not All Influence Is Born Equal: On The Effects Of Various Types Of Behavioral Influence Relationships On Social Media, Chathurani Senevirathna

Electronic Theses and Dissertations, 2020-

Typically, online social influence is analyzed using a single metric approach. However, social influence is not monolithic; different users exercise different influences in different ways, and influence is correlated with the user and content-specific attributes. One such attribute could be whether the action is an initiation of a new post, a contribution to a post, or a sharing of an existing post. Thus, this dissertation uses this platform-independent action classification and models the influence as multiple entities and examines social networks through the perspective of behavioral influence propagation. Two empirical studies are present in this dissertation. The first study presents …


Studying The Electrostatic Effects On The Dynamics Of Charged Lunar Dust Via Discrete Element Method, Hao Wang Jan 2022

Studying The Electrostatic Effects On The Dynamics Of Charged Lunar Dust Via Discrete Element Method, Hao Wang

Electronic Theses and Dissertations, 2020-

Dust problems raise significant concerns in planetary surface exploration. The unusual behavior of the dust particles that surround the vehicle after engine cutoff has the potential to have more of an influence on surface systems than the high velocity lunar rocket plume ejecta in the landing process. A prevailing hypothesis attributes the levitation and transport of dust particles on the surface of airless bodies to the electrostatic effects and electric field. However, there is no accurate model considering the inter-particle electrostatic interactions, especially when the particles are charged by plume. This dissertation aims to understand the behavior of charged lunar …


Shape Parameter & Nodal Distribution Insensitive Radial Basis Functions For Nonlinear Optimal Control Problems, Ahmed Elsadek Ahmed Elshafee Seleit Jan 2022

Shape Parameter & Nodal Distribution Insensitive Radial Basis Functions For Nonlinear Optimal Control Problems, Ahmed Elsadek Ahmed Elshafee Seleit

Electronic Theses and Dissertations, 2020-

Computational optimal control relies mainly on pseudospectral methods. The use of Chebyshev and Legendre polynomials is ubiquitous in the literature. This family of methods has good accuracy characteristics but constraints the nodal distribution to a certain grid that is denser at the boundaries. In this work, a set of novel Coupled Radial Basis Functions (CRBFs) is introduced as an approximation means for the nonlinear optimal control problem. CRBFs are real-valued Radial Basis Functions (RBFs) augmented with a conical spline. They do not require a specific nodal distribution. A plethora of research articles were published on the optimization of the shape …


An Econometric Analysis Of Domestic Aviation In The Us, Sudipta Dey Tirtha Jan 2022

An Econometric Analysis Of Domestic Aviation In The Us, Sudipta Dey Tirtha

Electronic Theses and Dissertations, 2020-

In this dissertation, we examine two dimensions of domestic aviation - demand and delay - that directly influence economic impact of the sector. We conduct a comprehensive analysis of airline demand employing airline data compiled by Bureau of Transportation Statistics. The demand analysis is conducted in three steps. First, we propose a novel modeling approach for modeling airline demand evolution over time. Specifically, we develop a joint panel group generalized ordered probit (GGOP) model system for modeling air passenger arrivals and departures in a discretized framework that subsumes the traditional linear regression approach. Further, we consider the influence of observed …


Automated Vehicle To Vehicle Conflict Analysis At Signalized Intersections By Camera And Lidar Sensor Fusion, Alabi Mehzabin Anisha Jan 2022

Automated Vehicle To Vehicle Conflict Analysis At Signalized Intersections By Camera And Lidar Sensor Fusion, Alabi Mehzabin Anisha

Electronic Theses and Dissertations, 2020-

This research presents an approach for safety diagnosis using sensor fusion techniques. This work fuses the outputs of a roadside low-resolution camera and a solid-state LiDAR. For vehicle classification and detection in videos, the YOLO v5 object detection model was utilized. The raw 3D point clouds generated by the LiDAR are processed by two manual steps - ground plane transformation and background segmentation, and two real-time steps - foreground clustering, and bounding box fitting. Taking the generated 2D bounding boxes of both camera and LiDAR, we associate the common bounding box pairs by thresholding on the Euclidean distance threshold of …


Development Of A Multivariate Poisson Hidden Markov Model For Application In Educational Data Mining, Shahab Boumi Jan 2022

Development Of A Multivariate Poisson Hidden Markov Model For Application In Educational Data Mining, Shahab Boumi

Electronic Theses and Dissertations, 2020-

Managers and policymakers in higher education institutions try to improve graduation rates and decrease halt rates. To achieve this goal, it is important to understand academic and demographic factors that correlate with academic performance. Many studies in the field of education analytics have identified student grade point averages (GPA) as an important indicator and predictor of final academic outcomes (graduating or halting their studies). While semester-to-semester fluctuations in GPA are considered normal, significant changes in academic performance may warrant more thorough investigation and consideration, particularly with regard to final academic outcomes. However, it is challenging to represent complex academic trajectories …


Non-Invasive Detection Of Elevated Intracranial Pressure Using Spontaneous Tympanic Membrane Pulsation, Rajkumar Dhar Jan 2022

Non-Invasive Detection Of Elevated Intracranial Pressure Using Spontaneous Tympanic Membrane Pulsation, Rajkumar Dhar

Electronic Theses and Dissertations, 2020-

Monitoring intracranial pressure (ICP) is a standard diagnostic tool for various neurological conditions such as head injury, ruptured aneurysms, intracerebral and intracranial hemorrhage, and hydrocephalus. Currently, ICP monitoring relies on invasive pressure measurements. These include intraventricular catheter, subdural screw, epidural sensor, and lumbar puncture. Invasive methods pose the risk of infection and hemorrhage, are expensive, and require special clinical skills. A noninvasive method that is reliable, simple to use, low-cost, and provides easily interpretable results can help avoid the complications associated with the invasive methods. This study proposes a novel method for noninvasive ICP monitoring using tympanic membrane pulsation (TMp). …


Signal Enhancement Techniques For Nanoscale Infrared Spectroscopy Using Fractal Plasmonic Structures, Guntis Rutins Jan 2022

Signal Enhancement Techniques For Nanoscale Infrared Spectroscopy Using Fractal Plasmonic Structures, Guntis Rutins

Electronic Theses and Dissertations, 2020-

Exploring phenomena occurring at the molecular level is critical to deepen our understanding of the living world. However conventional analytical tools are often limited in both spatial resolution and sensitivity. In this work we evaluate how fractal plasmonic structures can be developed for Surface Enhanced InfraRed Absorption (SEIRA) substrates to boost the infrared fingerprint signal of unknown single entities such as nanomaterials, virus or other biological systems. In this thesis, we present an overview of developments using light-matter interaction to push the limit of spatial resolution and sensitivity (Chapter 1). We discuss technological advances that allow nanoscale infrared spectroscopy despite …