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Full-Text Articles in Engineering

Speech Coding Based On A Hybrid Approach: Dct, Huffman And Run-Length Coding, Sundos Abdulameer Alazawi, Esraa Jaffar Baker, Shahbaa Mohammed Abdulmaged Dec 2024

Speech Coding Based On A Hybrid Approach: Dct, Huffman And Run-Length Coding, Sundos Abdulameer Alazawi, Esraa Jaffar Baker, Shahbaa Mohammed Abdulmaged

Al-Esraa University College Journal for Engineering Sciences

The exponential expansion of data in the digital world necessitates the development of effective methods for data transmission and storage. Data compression (DC) strategies are suggested to reduce the quantity of data stored or conveyed due to constrained resources. As a result of DC ideas' ability to efficiently use existing storage space and transmission capacity, different methods have been developed in various areas. Speech coding is a lossy method of coding; therefore, the output signal differs slightly from the input signal. Speech coding is useful for message encryption, communication over long distances and speech quality. In the fields of digital …


The Evolution Of The University Of Al-Anbar Urban Planning Based On The Mental Picture's Diversity And The Contemporary Planning Spaces Filling, Ali Abdulsamea Hameed Dec 2024

The Evolution Of The University Of Al-Anbar Urban Planning Based On The Mental Picture's Diversity And The Contemporary Planning Spaces Filling, Ali Abdulsamea Hameed

Al-Esraa University College Journal for Engineering Sciences

This research concentrated on the role of environmental graphic design (EGD) and the place-making idea in the interior environment of Al-Anbar University. To develop an identity being visual for the University of Al-Anbar internal environment (IE) is this goal of project. The search sought to create and enhance the shape of the internal University of Al-Anbar vacuum by reviving the idea of place building. In order to build and filling the internal emptiness of the campus, the identity being visual must also be strengthened. The descriptive analytical approach was chosen since it was best suited to achieve the goal of …


Exploring The Benefits Of Feature Selection Based On Bat Algorithm And Deep Learning In Brain Cancer Diagnosis, Noor Fawzi Shafiq Dec 2024

Exploring The Benefits Of Feature Selection Based On Bat Algorithm And Deep Learning In Brain Cancer Diagnosis, Noor Fawzi Shafiq

Al-Esraa University College Journal for Engineering Sciences

Brain cancer is considered one of the most dangerous types that must be treated as soon as possible. Therefore, it is necessary to detect brain cancer in its early stages to enhance the diagnosis of the condition. This study proposes to combine the bat algorithm (BA) with deep learning methods to identify and classify brain tumors in medical images accurately.

In this paper, the bat algorithm was used to select distinctive features from the input brain images. The Bat Algorithm (BA) is a metaheuristic optimization algorithm that mimics the echolocation behavior of bats. It efficiently explores the feature space to …


An Intelligent System Using Deep Learning For Healthcare Monitoring In Light Of The Covid-19 And Future Pandemics Based On Iot, Sara Salman Qasim, Rajaa J. Khanjar, Jamal Nasir Hasoon, Baesher Abdullateff Abad, Ali Hussein Fadil, Shajan.M. Alsowaidi Dec 2024

An Intelligent System Using Deep Learning For Healthcare Monitoring In Light Of The Covid-19 And Future Pandemics Based On Iot, Sara Salman Qasim, Rajaa J. Khanjar, Jamal Nasir Hasoon, Baesher Abdullateff Abad, Ali Hussein Fadil, Shajan.M. Alsowaidi

Al-Esraa University College Journal for Engineering Sciences

Recently, the Internet of Things has become a compelling research field as a new topic of research in various disciplines, particularly in the field of healthcare, because the Internet of Things is rebuilding modern healthcare systems by integrating technology, economics, and social perspectives. The development of healthcare systems from traditional to more personalized systems in which patients can be easily diagnosed, monitored and treated and many people can be helped. People are treated and cared for remotely and this is what some people need in the crisis the world has been through like COVID-19. This epidemic is caused by the …


Capacity Of Self Compact Concrete Walls Using Attapulgite As A Partial Replacement Of Cement Under One Way And Two Way Action Restriction, Wissam Kadhim Alsaraj, Luma Abdul Ghani Zghair, Akhlas Hashem Mohammed Dec 2024

Capacity Of Self Compact Concrete Walls Using Attapulgite As A Partial Replacement Of Cement Under One Way And Two Way Action Restriction, Wissam Kadhim Alsaraj, Luma Abdul Ghani Zghair, Akhlas Hashem Mohammed

Al-Esraa University College Journal for Engineering Sciences

This investigation about the structural performance of sustainable self-compact concrete walls exposed to eccentric axial regularly dispersed loading, including the effect of aspect ratio (AR) and slenderness ratio (λ) by one-way and two-way action. The experimental program includes testing ten wall panels, the eccentricity of the loading system equivalent to one-sixth of depth. These wall panels are separated into four groups, each one consisting of three specimens. first and second groups clarify the aspect ratio (H/L) effect. The results indicated for decreasing AR from (0.75 to 0.625), (0.625 to 0.5), and (0.75 to 0.5), the increase of final load is …


A Study On Improving The Accuracy And Effectiveness Of Similarity Detection Processes In Text Files Using Nlp Techniques, Noor Abdulmuttaleb Jaafar Dec 2024

A Study On Improving The Accuracy And Effectiveness Of Similarity Detection Processes In Text Files Using Nlp Techniques, Noor Abdulmuttaleb Jaafar

Al-Esraa University College Journal for Engineering Sciences

The rapid expansion of the Internet has revolutionized access to information, especially in the area of unstructured data, most of which consists of textual content. While instant access to information brings many advantages, it has also given rise to a prevalent problem – plagiarism. Copying and reusing materials without proper permission poses a significant threat to academic integrity and integrity. Rates of plagiarism, especially in academic and scientific publications, have risen with the advent of the Internet, reaching alarming levels, such as 60% in student projects. This study examines the proposed model that includes computation of similarity using cosine coefficients, …


Unveiling The Hidden Threat: How Wireless Networks Fuel Serious Cyber Attacks, Ibtesam Jomaa Hawi Dec 2024

Unveiling The Hidden Threat: How Wireless Networks Fuel Serious Cyber Attacks, Ibtesam Jomaa Hawi

Al-Esraa University College Journal for Engineering Sciences

The spread of wireless networks has led to an increase in serious cyber attacks due to their weak architecture. This article focuses on reevaluating cybersecurity in wireless network technology by integrating statistical information detection methods and artificial intelligence (AI) algorithms. To construct a wireless networking scenario that accurately reflects real-life conditions, we created a data fabrication that included four pre-existing anomalies as well as four newly introduced anomalies. The synthetic dataset created from these generation processes contains 20 thousand distinguishable values, which are later divided into training and validation sets. Using the strategy described before, we began to analyze the …


Engineered Microalgae Cultivations Systems: Conversion Of Wastewater Nutrients Into Biofuels And Bioplastics, Jacob Watkins Dec 2024

Engineered Microalgae Cultivations Systems: Conversion Of Wastewater Nutrients Into Biofuels And Bioplastics, Jacob Watkins

All Graduate Theses and Dissertations, Fall 2023 to Present

Dissolved Nitrogen and Phosphorus in wastewater can contribute to harmful algae blooms if released into the environment. One technology that can be used to recover dissolved nutrients from wastewater is the Rotating Algae Biofilm Reactor (RABR), which supports microalgae growth in an easily-harvested biofilm and produces nitrogenand phosphorus-rich biomass that can be used to produce slow-release fertilizers, biofuels, and compostable bioplastics. This thesis (1) examines the effects of several environmental factors on the biomass production rate and nutrient removal efficiency of RABRs treating municipal wastewater, (2) quantifies the composition and biofuel yields of microalgae biomass cultivated using a RABR at …


Analysis Of An Outdoor Pilot-Scale Rotating Algae Biofilm Reactor For Power Optimization, Ash-Enhanced Productivity, And Nutrient Uptake, Peter F. Jeppesen Dec 2024

Analysis Of An Outdoor Pilot-Scale Rotating Algae Biofilm Reactor For Power Optimization, Ash-Enhanced Productivity, And Nutrient Uptake, Peter F. Jeppesen

All Graduate Theses and Dissertations, Fall 2023 to Present

Outdoor testing of a rotating algae biofilm reactor (RABR) was performed to see how well it could remove nutrients from water and produce algae. By adjusting the operation settings, we found the lowest power needed to remove nitrogen and phosphorus. The lowest power values needed were 1.36 kWh per kilogram of nitrogen and 20.1 kWh per kilogram of phosphorus. The algae production rate reached a maximum of 7.09 grams per square meter per day. Detailed analysis showed that the reactor worked like a continuous flow system, and the performance was influenced by factors including light and temperature. The results also …


Multi-Modal Investigation Of The Bone Micro- And Ultrastructure, And Elemental Distribution In The Presence Of Mg-Xgd Screws At Mid-Term Healing Stages, Kamila Iskhakova, Hanna Cwieka, Svenja Meers, Heike Helmholz, Anton Davydok, Malte Storm, Ivo Matteo Baltruschat, Silvia Galli, Daniel Pröfrock, Olga Will, Mirko Gerle, Timo Damm, Sandra Sefa, Weilue He, Keith Macrenaris, Malte Soujon, Felix Beckmann, Julian Moosmann, Thomas O'Hallaran, Roger J. Guillory, D. C.Florian Wieland, Berit Zeller-Plumhoff, Regine Willumeit-Römer Nov 2024

Multi-Modal Investigation Of The Bone Micro- And Ultrastructure, And Elemental Distribution In The Presence Of Mg-Xgd Screws At Mid-Term Healing Stages, Kamila Iskhakova, Hanna Cwieka, Svenja Meers, Heike Helmholz, Anton Davydok, Malte Storm, Ivo Matteo Baltruschat, Silvia Galli, Daniel Pröfrock, Olga Will, Mirko Gerle, Timo Damm, Sandra Sefa, Weilue He, Keith Macrenaris, Malte Soujon, Felix Beckmann, Julian Moosmann, Thomas O'Hallaran, Roger J. Guillory, D. C.Florian Wieland, Berit Zeller-Plumhoff, Regine Willumeit-Römer

Michigan Tech Publications, Part 2

Magnesium (Mg) – based alloys are becoming attractive materials for medical applications as temporary bone implants for support of fracture healing, e.g. as a suture anchor. Due to their mechanical properties and biocompatibility, they may replace titanium or stainless-steel implants, commonly used in orthopedic field. Nevertheless, patient safety has to be assured by finding a long-term balance between metal degradation, osseointegration, bone ultrastructure adaptation and element distribution in organs. In order to determine the implant behavior and its influence on bone and tissues, we investigated two Mg alloys with gadolinium contents of 5 and 10 wt percent in comparison to …


Radiopaque Femnn-Mo Composite Drawn Filled Tubing Wires For Braided Absorbable Neurovascular Devices, Adam J. Griebel, Petra Maier, Henry D. Summers, Benjamin Clausius, Isabella Kanasty, Weilue He, Nicholas Peterson, Carolyn Czerniak, Alexander A. Oliver, David F. Kallmes, Ramanathan Kadirvel, Jeremy E. Schaffer, Roger J. Guillory Oct 2024

Radiopaque Femnn-Mo Composite Drawn Filled Tubing Wires For Braided Absorbable Neurovascular Devices, Adam J. Griebel, Petra Maier, Henry D. Summers, Benjamin Clausius, Isabella Kanasty, Weilue He, Nicholas Peterson, Carolyn Czerniak, Alexander A. Oliver, David F. Kallmes, Ramanathan Kadirvel, Jeremy E. Schaffer, Roger J. Guillory

Michigan Tech Publications, Part 2

Flow diverter devices are small stents used to divert blood flow away from aneurysms in the brain, stagnating flow and inducing intra-aneurysmal thrombosis which in time will prevent aneurysm rupture. Current devices are formed from thin (∼25 μm) wires which will remain in place long after the aneurysm has been mitigated. As their continued presence could lead to secondary complications, an absorbable flow diverter which dissolves into the body after aneurysm occlusion is desirable. The absorbable metals investigated to date struggle to achieve the necessary combination of strength, elasticity, corrosion rate, fragmentation resistance, radiopacity, and biocompatibility. This work proposes and …


Exploring The Identification Of Autoregression Model By General Least Deviation Method, Mostafa Abotaleb, Tatiana Makarovskikh, Ramadhan, Ali J Sep 2024

Exploring The Identification Of Autoregression Model By General Least Deviation Method, Mostafa Abotaleb, Tatiana Makarovskikh, Ramadhan, Ali J

Al-Bahir Journal for Engineering and Pure Sciences

We are considering a novel method for analyzing time series data that relies on quasi-linear recurrence relations. Unlike neural networks, this approach allows for directly formulating high-quality quasi-linear difference equations that accurately represent the studied process. Techniques for determining the parameters of a single equation have been devised and validated. This work discusses and tests a technique for identifying the parameters of a quasi-linear recurrence equation. This approach is employed to tackle the issue of regression analysis including observable variables that are mutually dependent. It enables the utilization of the Generalized Least Deviations Method (GLDM). This model was utilized in …


Development Of A Haptic System For Robot-Assisted Femur Fracture Surgery, Fayez H. Alruwaili Sep 2024

Development Of A Haptic System For Robot-Assisted Femur Fracture Surgery, Fayez H. Alruwaili

Theses and Dissertations

Robot-assisted surgery has emerged within the field of surgical technology, driven by the need for greater accuracy and speed in the ongoing evolution of healthcare. This advancement has influenced numerous areas requiring enhancements to achieve optimal surgical results. However, surgical robotics tends to lack the surgeon’s connection to the operation, creating a gap in the intuitive skill set required for successful operations. The gap is seen through the lack of sense of touch, which may result in tissue damage and additional injury when the robot interacts with the patient. Furthermore, challenges faced during femur fracture surgery have positioned robot-assisted surgery …


Injectable Hydrogels That Can Measure Radiation At Body Temperature, Daniel Joseph Ball Sep 2024

Injectable Hydrogels That Can Measure Radiation At Body Temperature, Daniel Joseph Ball

Theses and Dissertations

Hydrogel-based radiation dosimeters are used to calibrate and validate radiation delivered by linear accelerators used in radiotherapy. Specifically, Fricke hydrogel-based dosimeters containing ferrous ion complexes oxidize upon exposure to radiation, leading to a change in optical density that can be measured via a color change in a photometric reagent. While gelatin-based Fricke hydrogels are routinely used to measure radiation, these hydrogels are unstable at body temperature, and it is currently not possible to noninvasively measure radiation dose inside a patient. This study reports the synthesis and characterization of self-forming hydrogels containing Fricke components that are stable at body temperature. The …


Nanofiber-Hydrogel Composite Scaffold Fabrication Methods For Peripheral Nerve Regeneration, Jacob Lee Carter Sep 2024

Nanofiber-Hydrogel Composite Scaffold Fabrication Methods For Peripheral Nerve Regeneration, Jacob Lee Carter

Theses and Dissertations

Nerve graft conduits (NGCs) are a rapidly advancing field for treating peripheral nerve injuries that aim to guide the growth of regenerating axons across damaged gaps. A more effective NGC can be manufactured by combining the use of nanofibers to act as guidewires within a 3-D hydrogel that imitates the extracellular matrix of nerve tissue. Several methods have been developed to embed aligned nanofibers in an ordered architecture within a hydrogel matrix. The first method involves layer-by-layer additive manufacturing to create NGCs with rows of polycaprolactone (PCL) nanofibers surrounded by a gelatin methacrylate (GelMe) hydrogel in a 3-D structure. A …


Finite Element Analysis Of The Bearing Component Of Total Ankle Replacement Implants During The Stance Phase Of The Gait Cycle, S J. Hazelwood, Mohammad N. Noori, Naudereh B. Noori, Timothy S. Jain, Amanda Anderson, Joseph Rencis Sep 2024

Finite Element Analysis Of The Bearing Component Of Total Ankle Replacement Implants During The Stance Phase Of The Gait Cycle, S J. Hazelwood, Mohammad N. Noori, Naudereh B. Noori, Timothy S. Jain, Amanda Anderson, Joseph Rencis

Biomedical Engineering

Total ankle arthroplasty (TAA) is a motion-preserving treatment for end-stage ankle arthritis. An effective tool for analyzing these implants’ mechanical performance and longevity in silico is finite element analysis (FEA). An FEA in ABAQUS was used to statically analyze the mechanical behavior of the ultra-high-molecular-weight polyethylene (UHMWPE) bearing component at varying dorsiflexion/plantarflexion ankle angles and axial loading conditions during the stance phase of the gait cycle for a single cycle. The von Mises stress and contact pressure were examined on the articulating surface of the bearing component in two newly installed fixed-bearing TAA implants (Wright Medical INBONE II and Exactech …


In Silico Modelling And Docking Simulation Of Egfr-Targeted Diphtheria Toxin Chimera With Various Targeting Moieties, Muhammad Afif Naufal Bmed, Benedictus Ansell Susanto Bmed, Talitha Dinda Gunawan Bmed, Azhar Ridha Lukman Bmed, Alifa Rahma Rizqina Bmed, Muhammad Misbahul Fuad Bmed Aug 2024

In Silico Modelling And Docking Simulation Of Egfr-Targeted Diphtheria Toxin Chimera With Various Targeting Moieties, Muhammad Afif Naufal Bmed, Benedictus Ansell Susanto Bmed, Talitha Dinda Gunawan Bmed, Azhar Ridha Lukman Bmed, Alifa Rahma Rizqina Bmed, Muhammad Misbahul Fuad Bmed

Indonesian Journal of Medical Chemistry and Bioinformatics

Introduction: Cancer is a major etiology of death worldwide due to high mortality and suboptimal medicine. However, an emerging field, targeted therapy enabled a more selective and effective therapeutic action. This article aims to analyze in-silico the hypothetical targeted therapy agent that is combinations of conjugate consisting of EGFR targeting moieties and diphtheria toxin (DT-390).

Method: Our novel peptide is a conjugate of a novel EGFR targeting peptide and DT-390, forming a chimera. The tertiary structure was predicted using AlphaFold 2.0. The best IDDT scoring and stereochemistry profiles were utilized. The HADDOCK2.4 webserver modelled the docking between our …


The Prospect Of Indonesian Herbal As An Alternative Treatment For Covid-19 Patient: A Literature-Based Study, Hadi Sunaryo, Wahyu Hidayati Aug 2024

The Prospect Of Indonesian Herbal As An Alternative Treatment For Covid-19 Patient: A Literature-Based Study, Hadi Sunaryo, Wahyu Hidayati

Indonesian Journal of Medical Chemistry and Bioinformatics

Coronavirus disease 2019 (COVID-19) is a new disease caused by a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The disease has several symptoms from mild to severe and could lead to death for comorbidities and the elderly. Therefore, the infections and mortality cases keep growing day by day, moreover many authorities are trying to suppress it by applying several health protocols, including medicines. Several studies were conducted on drug discovery from plants to cure the disease. The article aimed to do a narrative review about the prospect of JAMU becoming an alternative medicine to cure COVID-19 by mapping …


A Novel Perfused Contusion Spinal Cord Injury Model To Assess Rapid Mechanical Properties Changes After Blood Spinal Cord Barrier Breakdown, Laura De Marchi Aug 2024

A Novel Perfused Contusion Spinal Cord Injury Model To Assess Rapid Mechanical Properties Changes After Blood Spinal Cord Barrier Breakdown, Laura De Marchi

Theses and Dissertations

Blood-spinal cord barrier (BSCB) disruption exacerbates the tissue damage caused by spinal cord injury (SCI), but the mechanisms and dynamics of how the barrier breakdown affects the mechanical properties of the tissue remain unclear. The perfused bovine ex vivo indentation injury model described here represents a new platform to investigate the short-term effects of altered blood flow and vascular permeability following traumatic spinal cord injury. Our results indicate that injured cords exhibit changes to bulk perfusion, as evidenced by laser speckle contrast imaging, in addition to decreased barrier function shortly after injury. Indentation tests that simultaneously simulate a crush injury …


One Possible Solution To The Endo Challenge For Earlier, Low Cost, Non-Invasive Diagnosis Of Endometriosis, Charles F. Babbs Aug 2024

One Possible Solution To The Endo Challenge For Earlier, Low Cost, Non-Invasive Diagnosis Of Endometriosis, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

This short paper outlines a potential solution to the ENDO Challenge posed by the US National Institutes of Health to spur development of painless, noninvasive diagnostic tools for early diagnosis in women suffering needlessly from endometriosis. Endometriosis is a common condition caused by regurgitation of menses backwards through the Fallopian tubes from the uterine cavity into the abdominal cavity during menstruation. A few still viable endometrial cells then implant widely and unpredictably throughout the abdominal cavity and become established on the surfaces of internal organs and the abdominal wall. There they live and remain responsive to cyclic hormones. The resulting …


Prostate Tissue Motion Tracking And Ultrasound Elastography Using Tissue Mechanics Derived Constraints, Tristan S. Curry Aug 2024

Prostate Tissue Motion Tracking And Ultrasound Elastography Using Tissue Mechanics Derived Constraints, Tristan S. Curry

Electronic Thesis and Dissertation Repository

Current prostate cancer detection methods can be costly to obtain, such as magnetic resonance imaging, or lack specificity, such as a digital rectal exam. Ultrasound elastography, a method that can be used to develop and test algorithms that output stiffness, strain, and displacement data captured by ultrasound radio frequency readings, offers a potential solution to these challenges. An initial algorithm utilizing dynamic programming and analytic minimization estimates the radial and angular displacements from a pre- and post-compression data set to determine the required material properties. This estimate of displacements is then refined through an algorithm where incompressibility, Laplacian smoothing, and …


Towards The Development Of Wearable Tremor Suppression Systems Combining Functional Electrical Stimulation And Mechanical Actuation, Zahra Habibollahi Aug 2024

Towards The Development Of Wearable Tremor Suppression Systems Combining Functional Electrical Stimulation And Mechanical Actuation, Zahra Habibollahi

Electronic Thesis and Dissertation Repository

Parkinson's disease (PD), the second most prevalent neurological disorder, is characterized by motor and non-motor symptoms including tremor. Wearable tremor suppression devices (WTSDs), have shown promising results for tremor reduction, using functional electrical stimulation (FES) or active actuators. However, results and study procedures are not consistent in the literature. Although stimulations below and above motor threshold can suppress tremor, the mechanisms of the first is still not clear, and the second might lead to muscle fatigue and discomfort over time. While active actuators have shown better results for tremor suppression, they are often heavy and bulky for daily use. Lastly, …


Metabolite Biomarker Discovery For Lung Cancer Using Machine Learning, Ariski Fajarido, Linda Erlina, Aryo Tedjo, Fadilah Fadilah, Wawaimuli Arozal Aug 2024

Metabolite Biomarker Discovery For Lung Cancer Using Machine Learning, Ariski Fajarido, Linda Erlina, Aryo Tedjo, Fadilah Fadilah, Wawaimuli Arozal

Indonesian Journal of Medical Chemistry and Bioinformatics

Lung cancer is the leading cause of cancer death worldwide. About 2.1 million lung cancer patients were diagnosed in 2018, accounting for about 11.6% of all newly diagnosed cancer cases. For lung cancer, blood is the first choice as a source of screening biomarker candidates. Blood biomarkers provide a snapshot of the patient's entire body, including the primary tumor, metastatic disease, immune response, and peritumoral stroma. However, sputum sampling, bronchial lavage or aspiration, exhaled breath (EB), and airway epithelial sampling represent unique samples for lung cancer and other airway cancers as potential sources for alternative biomarkers. Metabolites are products of …


Functional Near-Infrared Spectroscopy As A Bedside Neuroimaging Tool For Neonatal Brain Monitoring And Injury Characterization, Lingkai Tang Aug 2024

Functional Near-Infrared Spectroscopy As A Bedside Neuroimaging Tool For Neonatal Brain Monitoring And Injury Characterization, Lingkai Tang

Electronic Thesis and Dissertation Repository

Early brain injury in neonates is a common neurological complication associated with high mortality rates and long-term morbidities. Two common types of injury are intraventricular hemorrhage (IVH) and hypoxic ischemic encephalopathy (HIE). Currently used clinical neuroimaging tools for diagnosing or monitoring the injury have limitations, e.g., cranial ultrasound is not for continuous monitoring of the evolution of injury so it could miss the optimal timing for intervention, and magnetic resonance imaging (MRI) is not very accessible for infants in neonatal intensive care unit. Functional near-infrared spectroscopy (fNIRS) can be an alternative imaging technique as it can be used at the …


High-Throughput Analysis Of Topographical Cues For The Expansion Of Murine Pluripotent Stem Cells, Abigail Anne Conner, Yuan Yao, Sarah W. Chan, Deepak Jain, Suzanne M. Wong, Evelyn K. Yim, Muhammad Rizwan Aug 2024

High-Throughput Analysis Of Topographical Cues For The Expansion Of Murine Pluripotent Stem Cells, Abigail Anne Conner, Yuan Yao, Sarah W. Chan, Deepak Jain, Suzanne M. Wong, Evelyn K. Yim, Muhammad Rizwan

Michigan Tech Publications, Part 2

The expansion of pluripotent stem cells (PSCs) in vitro remains a critical barrier to their use in tissue engineering and regenerative medicine. Biochemical methods for PSC expansion are known to produce heterogeneous cell populations with varying states of pluripotency and are cost-intensive, hindering their clinical translation. Engineering biomaterials to physically control PSC fate offers an alternative approach. Surface or substrate topography is a promising design parameter for engineering biomaterials. Topographical cues have been shown to elicit profound effects on stem cell differentiation and proliferation. Previous reports have shown isotropic substrate topographies to be promising in expanding PSCs. However, the optimal …


Development And Validation Of The Motion Shirt: A Wearable Sensor System For Monitoring Upper Limb Motion In Shoulder Joint Replacement Patients, Sohrob Milanizadeh Aug 2024

Development And Validation Of The Motion Shirt: A Wearable Sensor System For Monitoring Upper Limb Motion In Shoulder Joint Replacement Patients, Sohrob Milanizadeh

Electronic Thesis and Dissertation Repository

Wearable sensors have become the study topic of researchers across various clinical disciplines, presenting promising avenues for their integration into clinical practices. Inertial measurement units (IMUs) have become significantly notable among the variety of sensor types, due to their non-invasive, and lightweight design. Moreover, they are increasingly used and applied in novel motion technologies since IMUs collect precise motion and orientation data when attached to specified body regions. In this dissertation, a wearable sensor system known as the Motion Shirt, equipped with 5 IMU sensors, has been developed and embedded into a flexible garment, enables continuous and accurate arms and …


In-House Polydimethylsiloxane Microfluidic Device On Single Cell Trapping And Culturing Of Leukemia Cell Line: Comparison Between Conventional And Conventional With Centrifugal Methods, Alongkorn Pimpin, Sudchaya Bhanpattanakul, Tepparit Wongpakham, Chomkwan Tawatcharaporn, Thanawit Siha-Umphai, Mookdapa Sinsiriphan, Atikan Chalermchuang, Tewan Tongmanee, Attawut Thanomsridetchai, Thammawit Suwannaphan, Witsaroot Sripumkhaie, Pattaraluck Pattamang, Mayuree Chanasakulniyom, Praprudee Piyaviriyakul, Wutthinun Jeamsaksiri, Achariya Sailasuta, Theerawat Tharasanit, Theerayuth Kaewamatawong Aug 2024

In-House Polydimethylsiloxane Microfluidic Device On Single Cell Trapping And Culturing Of Leukemia Cell Line: Comparison Between Conventional And Conventional With Centrifugal Methods, Alongkorn Pimpin, Sudchaya Bhanpattanakul, Tepparit Wongpakham, Chomkwan Tawatcharaporn, Thanawit Siha-Umphai, Mookdapa Sinsiriphan, Atikan Chalermchuang, Tewan Tongmanee, Attawut Thanomsridetchai, Thammawit Suwannaphan, Witsaroot Sripumkhaie, Pattaraluck Pattamang, Mayuree Chanasakulniyom, Praprudee Piyaviriyakul, Wutthinun Jeamsaksiri, Achariya Sailasuta, Theerawat Tharasanit, Theerayuth Kaewamatawong

The Thai Journal of Veterinary Medicine

To develop a suitable model to study biological and characterization of Cancer stem cells (CSCs), single cell trapping and culturing using microfluidic techniques have become a high-through put system that can manage and control microenvironment and practical intracellular analysis. The aim of this study was to develop and validate a microfluidic device for single cell trapping and culturing using the leukemia cell line as a cell model. Comparison between conventional and conventional with centrifugal methods was also analyzed. To compare trapping efficacy between these 2 methods, leukemia cell concentration of 1.5×106 cells/ml was loaded with a flow rate of 0.25 …


Analysis Of Healthy Glenohumeral Arthrokinematics And Anatomic Shoulder Implant Subluxation Using 4dct, Kylie Kiera Paliani Aug 2024

Analysis Of Healthy Glenohumeral Arthrokinematics And Anatomic Shoulder Implant Subluxation Using 4dct, Kylie Kiera Paliani

Electronic Thesis and Dissertation Repository

The shoulder is the most mobile joint in the human body, with the glenohumeral joint specifically allowing a wide range of motion and a high incidence of instability due to its ability to translate, as well as rotate in its socket. However, the extent of translation in a healthy glenohumeral joint is not well-established. Additionally, it is unclear if subluxation correction after anatomic total shoulder arthroplasty (TSA) with posterior augmented glenoid (PAG) implants remains consistent throughout active motion. This thesis aimed to evaluate healthy glenohumeral arthrokinematics to benchmark normal joint proximity and translation, and to assess if a TSA with …


The Role Of Transverse Plane Malalignment In Posterolateral Corner Complex Injury, Larissa M. Madia Aug 2024

The Role Of Transverse Plane Malalignment In Posterolateral Corner Complex Injury, Larissa M. Madia

Electronic Thesis and Dissertation Repository

The posterolateral corner (PLC) is a complex of ligaments and soft tissues in the knee that primarily constrain external tibial rotation. Neglecting PLC injury is a contributing factor in graft failure following cruciate ligament reconstruction. This emphasizes the importance of understanding PLC injury mechanisms, considering their disposition to multi-ligament tears. The PLC can be damaged by hyperextension. Tibial torsion, a twisting of the tibia longitudinally relative to the femur, offsets the transverse knee alignment, consequently altering the loading of soft tissues. Therefore, the objective of this investigation was to determine if tibial torsion affects loading of PLC components during hyperextension, …


Design Of A Portable Fast Scan Cyclic Voltammetry Device Utilizing Pulse Width Modulation For Waveform Generation, Nora Szymkowski Aug 2024

Design Of A Portable Fast Scan Cyclic Voltammetry Device Utilizing Pulse Width Modulation For Waveform Generation, Nora Szymkowski

Masters Theses

Fast Scan Cyclic Voltammetry (FSCV) is a widely used electrochemical technique for real-time measurement of the brain’s chemical messengers, including the molecule dopamine, with high temporal resolution. Currently the financial burden of performing FSCV is quite high, ranging from $8,000 to $20,000+ making the barrier to entry nearly insurmountable for laboratories and classrooms at small institutions. The purpose of this project was to develop a Do-It-Yourself (DIY), portable, and cost-effective FSCV system for use in laboratory and classroom settings. The project aimed to create a compact and cost-effective system that could be used by researchers and educators to study dopamine …