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Dissociation Of The Effects Of Serotonin Reuptake Inhibitor Fluoxetine In Prelimbic Cortex On Disruption Of Timing And Working Memory For Time By Neutral And Negative Emotional Events, Chance Christensen

Undergraduate Honors Capstone Projects

Learning and memory abilities are altered in disorders of the serotonergic system, in disorders such as such as depression, phobias, and post-traumatic stress disorder (PTSD). Among the processes impaired by emotional distracters, and whose dysregulation is documented in affective disorders, is the ability to time in the seconds-to-minutes range, i.e., interval timing. Presentation of distracters during timing tasks result in delays in responding suggesting a failure to maintain subjective time in working memory, as proposed by the Relative Time-Sharing (RTS) model. We investigated the role of the prelimbic cortex in the detrimental effect of anxiety-inducing distracters on the cognitive ability …

Regularity Of Performance On A Computer Tracking Task Is Different Between Concussed And Non-Concussed Individuals, Kedric James Glenn

Undergraduate Honors Capstone Projects

Concussion in athletics has raised public interest as more is learned about the damage done to the athlete. Some of the current field methods of assessing concussion do not look at neuro-cognitive recover, which can remain impaired long after the symptoms of concussion have passed. Other direct methods of assessing concussion are extremely expensive and are not easily portable.

We created a new assessment for concussion that is relatively inexpensive and portable using non-linear time series analysis of performance on a visual-motor tracking task. Approximate entropy (ApEn) is a tool that enables us to calculate the structure of variability form …