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Articles 31 - 60 of 128
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The Fate Of Anthropogenic Nitrogen Along Hydrologic Continuums: Patterns Of Transformation And Recycling In A Eutrophic Lake And Coastal Marine Sediments, Daniel K. Hoffman
The Fate Of Anthropogenic Nitrogen Along Hydrologic Continuums: Patterns Of Transformation And Recycling In A Eutrophic Lake And Coastal Marine Sediments, Daniel K. Hoffman
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Eutrophication of aquatic systems can have cascading effects along hydrological continua from watersheds to coasts that result in impaired ecosystem health. In freshwater systems, blooms of toxic, non-nitrogen (N) fixing cyanobacteria (cyanoHABs), such as Microcystis, proliferate due to external loading of chemically reduced forms of N (e.g., ammonium (NH4+) and urea), which promote growth and toxin production. In coastal marine systems, nutrient loading can promote harmful algae blooms and threaten vulnerable, native vegetation, such as seagrasses, which provide valuable ecosystem services but are under threat globally from anthropogenic stressors. This dissertation focuses on NH4+ cycling in the water column of …
Identification Of New Metabolic Mutations In The Fission Yeast Schizosaccharomyces Pombe That Sensitize The Cell To Hydroxyurea, Alaa Mahdi
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Cancer is a life-threatening illness and innovative research is therefore required to fuel the development of new anti-cancer therapies. As an anti-proliferative drug, hydroxyurea (HU) has been used in the treatment of various neoplastic and non-neoplastic diseases such as sickle cell anemia, psoriasis, and viral infections. HU is a well-known inhibitor of ribonucleotide reductase (RNR), an enzyme that generates dNTPs for DNA replication and repair. In our genetic screen in fission yeast looking for mutants with defects in checkpoint response, we also found a set of mutants that are highly sensitive to HU but with a functional checkpoint response. It …
Design Of A Novel Wearable Ultrasound Vest For Autonomous Monitoring Of The Heart Using Machine Learning, Garrett G. Goodman
Design Of A Novel Wearable Ultrasound Vest For Autonomous Monitoring Of The Heart Using Machine Learning, Garrett G. Goodman
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As the population of older individuals increases worldwide, the number of people with cardiovascular issues and diseases is also increasing. The rate at which individuals in the United States of America and worldwide that succumb to Cardiovascular Disease (CVD) is rising as well. Approximately 2,303 Americans die to some form of CVD per day according to the American Heart Association. Furthermore, the Center for Disease Control and Prevention states that 647,000 Americans die yearly due to some form of CVD, which equates to one person every 37 seconds. Finally, the World Health Organization reports that the number one cause of …
An Evaluation Of The Montgomery County Reentry Career Alliance Academy, Catherine Marliese Driver
An Evaluation Of The Montgomery County Reentry Career Alliance Academy, Catherine Marliese Driver
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As a result of a deterrence and incapacitation focused criminal justice system in the United States, reentry programming has become integral to both reduce criminal justice spending and mass incarceration. Reentry programming assists those released from prison with reintegration into society to prevent recidivism and allow the returning citizen to become a productive member of society. This study evaluated one such reentry program in Montgomery County Ohio. The Reentry Career Alliance Academy (RCAA) is a career focused work readiness curriculum that also includes workshops with community stakeholders. Evaluation was completed through paired T Test analysis in pre- and post-questionnaire responses. …
Comparing Rf Fingerprinting Performance Of Hobbyist And Commercial-Grade Sdrs, Travis R. Smith
Comparing Rf Fingerprinting Performance Of Hobbyist And Commercial-Grade Sdrs, Travis R. Smith
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Radio Frequency Fingerprinting (RFF) research typically uses expensive, laboratory grade receivers which have high dynamic range, very stable oscillators, large instantaneous bandwidth, multi-rate sampling, etc. In this study, the RFF effectiveness of lower grade receivers is considered. Using software-defined radios (SDRs) of different cost and performance, a linear regression model is developed to predict RFF performance. Unlike two previous studies of SDR effectiveness that used commercial and lab-grade SDRs, the experiment here focused on hobbyist and commercial-grade SDRs (RTL-SDR, B200-mini, N210). A regression model is proposed for a generic SDR. Using a full-factorial experiment matrix, the gain, sample rate, and …
Game Of Survival: External Actors' Support For Separatists, Joshua C. Underwood
Game Of Survival: External Actors' Support For Separatists, Joshua C. Underwood
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This research develops a novel model for external actors’ support for separatists.Three variables measuring external actors’ support are identified through two case studies, Kosovo Liberation Army and Liberation Tigers of Tamil Eelam, with an emphasis on Military Aid’s impact. The variables are then applied to a quantitative analysis of external actors’ support in a dataset of 75 observations during the years 1991-2020, utilizing the Uppsala Conflict Data Program External Support Dataset. The findings for this research show that Military Aid and Moral Support improve the probability of survival for a separatist group. A deeper analysis reveals that military aid among …
Hierarchical Structure, Properties And Bone Mechanics At Macro, Micro, And Nano Levels, Farah Mohammed Ridha Abdulateef Hamandi
Hierarchical Structure, Properties And Bone Mechanics At Macro, Micro, And Nano Levels, Farah Mohammed Ridha Abdulateef Hamandi
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This research focuses on the hierarchical structure of bone and associated mechanical properties at different scales to assess damage accumulation leading to premature failure, with or without instrumentation. In this work, an attempt was made to develop a framework of macro, micro, and nano damage accumulation models and implementing them to derive mechanical behavior of the bone. At macrolevel, retrospective evaluation of 313 subjects was conducted, and the damage of bone tissue was investigated with respect to subject demography including age, gender, race, body mass index (BMI), height and weight, and their role in initiating fracture. Experimental data utilized 28 …
The Thermal And Mechanical Characteristics Of Lithiated Peo Lagp Composite Electrolytes, Jacob Michael Denney
The Thermal And Mechanical Characteristics Of Lithiated Peo Lagp Composite Electrolytes, Jacob Michael Denney
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Lithium-ion batteries are part of a multibillion-dollar industry that strives to meet the demands for an increasingly advanced technological future. Flexible batteries can be easily adapted from emerging novel wearable electronics to electrical vehicles and advanced solar panels. Solid-state batteries can greatly reduce the risk of fire or leaking hazardous materials due to puncture. For the development of solid-state flexible lithium based batteries polymer-ceramic composites are attractive electrolyte candidates because of their combined properties, such as electrical, thermal and mechanical properties, that not only overcome limitations from the base materials but may also render some enhanced performances resulting from the …
Divalent Metal Cation Entry And Cytotoxicity In Jurkat T Cells: Role Of Trpm7 Channels, Alayna N. Mellott
Divalent Metal Cation Entry And Cytotoxicity In Jurkat T Cells: Role Of Trpm7 Channels, Alayna N. Mellott
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Humans are exposed daily to a variety of metals that can be harmful to our immune system. Although certain divalent metal cations are essential for numerous cellular functions and are critical trace elements in humans, the uptake mechanisms of these ions remain mostly unknown. Transient receptor potential melastatin 7 (TRPM7), which is expressed in a variety of human cell types, including lymphocytes and macrophages, conducts many divalent metal cations. TRPM7 channels are largely inactive under normal physiological conditions due to cytoplasmic magnesium acting as a channel inhibitor. Magnesium is a cofactor for many biochemical reactions. Low serum levels of magnesium, …
Development Of Tetrathiafulvalene Fused N-Heterocyclic Carbene Compounds, William J. Robinson Iii
Development Of Tetrathiafulvalene Fused N-Heterocyclic Carbene Compounds, William J. Robinson Iii
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Separately, N-Heterocyclic carbene and Tetrathiafulvalene compounds show great promise for a variety of applications. N-heterocyclic carbenes exhibit desirable metal bonding characteristics which allow for modulation of the metal center via back-bonding interactions. Additionally, this creates a system of increased bonding strength creating stable complexes. Tetrathiafulvalene exhibits strong redox-active and optical characteristics. These are owed to an increased aromaticity as oxidation of the compound occurs and thus, is stable through a multitude of oxidative states. The marriage of these two functionalization creates a unique opportunity for a “cure-all” compound, able to address many problems the world faces today including, but not …
Renca Macrobeads Inhibit Tumor Cell Growth Via Egfr Activation And Regulation Of Mef2 Isoform Expression, Prithy Caroline Martis
Renca Macrobeads Inhibit Tumor Cell Growth Via Egfr Activation And Regulation Of Mef2 Isoform Expression, Prithy Caroline Martis
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Tumors are heterogeneous systems, whose growth is influenced by intrinsic properties of malignant cells, external systemic factors (i.e. immune, neural, endocrine, etc.), and the dynamic interactions between tumor cells and their microenvironment. Given the inherent complexity of cancers, combined with the continual evolution of tumors and the development of treatment resistance, a precision medicine approach may not provide an optimal clinical response. Exploring a new paradigm that focuses on regulating cancer as a system may not only control tumor progression but also address the extraordinary challenges of tumor heterogeneity and disease recurrence in order to improve clinical outcomes. As a …
Characterization Of B3galt2 And Heg1 Expression In Dorsal Root Ganglia, Alexander H. Nguyen
Characterization Of B3galt2 And Heg1 Expression In Dorsal Root Ganglia, Alexander H. Nguyen
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Proprioception provides unique sensory feedback about the body’s orientation in space and this sensation is essential for creating specific motor functions and coordinated movement. During neurogenesis, unique genetic markers are expressed and classified as early, transient/middle, and late markers depending on their timing of expression. This study focuses on the expression patterns of two late markers: Heg1 and B3galt2. We investigated how expression of these two markers respond to peripheral nerve injury (PNI). We cloned and generated riboprobes to detect expression of B3galt2 and Heg1 in DRGs using in situ hybridization after transection of the sciatic nerve. B3galt2 hybridization in …
The Steady-State Analysis Of The Non-Isolated And Isolated Type Sepic Pwm Dc-Dc Converters For Ccm, Anuroop Reddy Dasari
The Steady-State Analysis Of The Non-Isolated And Isolated Type Sepic Pwm Dc-Dc Converters For Ccm, Anuroop Reddy Dasari
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The purpose of this thesis is to develop the theory for analysing and designing the non-isolated and isolated type of SEPIC converters for continuous conduction mode (CCM). The non-isolated converter has single output. The isolated converter considered has two cases: single output and multi-output. The principle of operation of each circuit is explained during different time intervals of the switching cycle. The analytical expressions for various characteristics of the circuits are derived, such as: MV DC and MIDC of the lossless and lossy converter; average and peak-to-peak currents through the inductors, primary and secondary windings of the transformer; average and …
Stream Clustering And Visualization Of Geotagged Text Data For Crisis Management, Nathaniel C. Crossman
Stream Clustering And Visualization Of Geotagged Text Data For Crisis Management, Nathaniel C. Crossman
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In the last decade, the advent of social media and microblogging services have inevitably changed our world. These services produce vast amounts of streaming data, and one of the most important ways of analyzing and discovering interesting trends in the streaming data is through clustering. In clustering streaming data, it is desirable to perform a single pass over incoming data, such that we do not need to process old data again, and the clustering model should evolve over time not to lose any important feature statistics of the data. In this research, we have developed a new clustering system that …
The Direct And Indirect Effects Of Mathematics Self-Efficacy On Intermediate Students’ Mathematics Growth, Susan Sipniewski
The Direct And Indirect Effects Of Mathematics Self-Efficacy On Intermediate Students’ Mathematics Growth, Susan Sipniewski
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In this study, the investigator sought to determine the extent to which mathematics self-efficacy affects mathematics growth among students in grades four and five. Included in this investigation is a hypothesized structural model that reflects Bandura’s (1977a, 1986, 1989) theory of self-efficacy. In part one of the investigation, each variable in the model (mathematics self-efficacy, self-regulation in mathematics, mathematics avoidance, mathematics anxiety, attitude toward mathematics, and mathematics growth) was analyzed to determine whether there were significant differences between genders in those specified variables. Findings revealed gender differences in two of the six variables, self-regulation in mathematics and mathematics avoidance. Females …
Examining The Influence Of Undergraduate Students’ Perceptions Of Academic Advising On Student-Institution Relationship Quality, Student Loyalty, And Enrollment Intentions: An Application Of Relationship Marketing In Higher Education, Linda Marie Hockaday
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As higher education institutions continue to compete for a declining population of students (National Student Clearinghouse Research Center, 2019), an increased focus on retaining existing students is required to maintain current levels of undergraduate enrollment (Elliott & Shin, 2002; Habley, Bloom, & Robbins, 2012; Judson & Taylor, 2014; Schertzer & Schertzer, 2004, Vianden & Barlow, 2014). Predominant student retention models (Astin, 1965; Bean, 1985; Tinto, 1987, 1993) emphasize the interaction between students and institutional representatives as a primary factor influencing the student experience and student decisions to continue enrollment in future academic terms. Although academic advisors are the institutional representative …
Optimization Study Of A Combined Wind-Solar Farm For A Specified Demand, Venkat Siddhartha Rama
Optimization Study Of A Combined Wind-Solar Farm For A Specified Demand, Venkat Siddhartha Rama
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At the present time, using wind and solar energy for producing electricity in the United States is becoming cost competitive. According to Lazard’s 2019 [36] levelized cost of energy (LCOE) analysis of a number of energy sources used for producing electricity in the United States, wind and solar are cheaper than natural gas and coal. While capital, maintenance, operation, and fuel costs are included in LCOE numbers, energy source intermittency is not. Intermittency is an important issue with wind and solar energy sources, but not with natural gas or coal energy sources. Combining wind and solar energy sources into one …
Generational Identity And The Wende: Institutional Influence And The Last Generation Of The Gdr, Jill H. Jackson
Generational Identity And The Wende: Institutional Influence And The Last Generation Of The Gdr, Jill H. Jackson
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Political and cultural institutions of the former German Democratic Republic (GDR) shaped generational identity before and after Germany’s Wende, or reunification. This thesis considers two memoirs, Zonenkinder and Meine freie deutsche Jugend, which were published after reunification and written by members of the GDR’s last generation. Contextualizing their memoirs in the context of the GDR’s political culture illustrates the degree to which memories are mediated by external factors and how in the confrontations with external assessments, portrayals emerge that focus on peculiarities rather than unifying features. Depictions of significant moments from the formative years of these authors demonstrate how social …
Topical Photodynamic Therapy Generates Microvesicle Particles, Oladayo Ayobami Oyebanji
Topical Photodynamic Therapy Generates Microvesicle Particles, Oladayo Ayobami Oyebanji
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Photodynamic therapy (PDT) involves the use of light at an appropriate wavelength acting on a photosensitizing chemical to cause cell death via generation of reactive oxygen species. PDT has been useful in the management of skin conditions (like acne, psoriasis) and cancers like superficial skin, esophageal and non-small cell lung cancers. In addition to these therapeutic effects, previous murine studies from our group have demonstrated that topical PDT induces immunosuppression in vivo. Thus, topical PDT of skin can generate systemic effects through unknown mechanisms. Our group showed that PDT induces an immunosuppressive effect which occurs partly via Platelet-Activating Factor Receptor …
Veteran Reintegration, Joan Lee Tolliver
Veteran Reintegration, Joan Lee Tolliver
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Veterans are a unique population and share a common experience: reintegration. The reintegration period can be a challenging experience, and affects things such as mental health and overall adjustment to civilian life. In order to examine reintegration more closely, interviews conducted by the Wright State’s Veterans Voices Project were used to complete this study. A checklist was used and consisted of nine themes identified in the relative literature related to reintegration: intimate relationships, familial relationships, children, education, employment, physical health, mental health, coping, and identity. Of the nine categories, employment was discussed most often (59.5%). Mental health was only discussed …
Quantifying Contributions To The Variance Of Permeability And Porosity Within The Western Belt Sandstones Of The Cypress Formation, Illinois Basin, Nathaniel Frederick Dulaney
Quantifying Contributions To The Variance Of Permeability And Porosity Within The Western Belt Sandstones Of The Cypress Formation, Illinois Basin, Nathaniel Frederick Dulaney
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One of the strategies for reducing the emission of the greenhouse gas carbon dioxide (CO2) and mitigating its accumulation into the Earth’s atmosphere is geologic sequestration (GSCO2). This process might be paired with enhanced oil recovery (EOR) within depleted oil reservoirs to provide an economic incentive for GSCO2. Heterogeneity within reservoirs (e.g. spatial differences in entry pressure, permeability, and porosity) can exert significant influence on the dynamics of fluid flow during EOR and GSCO2, and thus on the ultimate success of GSCO2-EOR. The Western Belt sandstones of the Cypress Formation in the Illinois Basin are candidate reservoirs for GSCO2-EOR. Heterogeneity …
Attitude Strength And Situational Strength As Moderators Of The Job Satisfaction – Job Performance Relationship, Joseph William Dagosta
Attitude Strength And Situational Strength As Moderators Of The Job Satisfaction – Job Performance Relationship, Joseph William Dagosta
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Workers who are satisfied with their jobs are better performers, but prior research has found a plethora of moderating variables between job satisfaction and job performance (Ostroff, 1992, Schleicher, Watt, & Greguras, 2004; Spector, 1997). Prior research has suggested that job attitude strength can strengthen the relationship between job satisfaction and job performance and that the relationships between personality variables and extra-role job performance are stronger in weak rather than strong workplace situations (Meyer et al., 2014; Shleicher et al., 2015). In the current study, I investigated the interaction between job satisfaction, job attitude strength, and situational strength on job …
Single-Pixel Camera Based Spatial Frequency Domain Imaging For Non-Contact Tissue Characterization, Alec M. Petrack
Single-Pixel Camera Based Spatial Frequency Domain Imaging For Non-Contact Tissue Characterization, Alec M. Petrack
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Optical imaging has demonstrated potential as a medical imaging modality for measuring tissue functionality. Recently, interest in fluorescence guided surgery has emerged from improvements in optical imaging that have allowed real-time feedback. Of the optical imaging modalities, spatial frequency domain imaging (SFDI) has gained a lot of interest. Unlike spectroscopic techniques, such as functional near infrared spectroscopy (fNIRS) and frequency domain spectroscopy that measure bulk tissue properties, SFDI quantifies tissue functionality locally and wide field making it practical for clinical applications. Unfortunately, traditional SFDI systems use multi-pixel detectors, which may not exhibit ideal spectral characteristics, have limited sensitivity, be expensive, …
Joint Shelf Design And Shelf Space Allocation Problem For Retailers, Hakan Gecili
Joint Shelf Design And Shelf Space Allocation Problem For Retailers, Hakan Gecili
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Although the retail business has been exploring innovative ways to engage shoppers, the COVID-19 pandemic has sped up their effort. Because of its unique benefits, physical stores will continue to remain an integral part of the overall retail business. However, to stay competitive, retailers will be forced to effectively utilize their available space in physical store (and even reduce it if need be), while offering a reasonably large assortment of products on their shelves. For many such retailers, the design of planograms – visual representation of products on shelves – is still driven by prior experience and intuition. Further, existing …
A Comparative Analysis Of Military And Non-Military Parent Engagement In Public Elementary Schools, Robin G. Fisher
A Comparative Analysis Of Military And Non-Military Parent Engagement In Public Elementary Schools, Robin G. Fisher
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The focus of this study was a comparison of military and non-military parent engagement levels in public elementary schools. A parent survey was used to collect data on the parent engagement levels of military and non-military parents to determine if there was a significant difference between the two populations, while controlling for income and education. In addition, the parent engagement levels of the military parents were analyzed based on the percentage of military students in each school. The objective was to determine if a higher percentage of military students in a school would increase the military parent engagement. Open-ended questions …
The Use Of Performance Measurement And Management In Small Ohio Municipalities, Yvonne M. Christopher
The Use Of Performance Measurement And Management In Small Ohio Municipalities, Yvonne M. Christopher
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As the dominant public management paradigm today, performance measurement and management systems are fundamental to increasing efficiency, accountability, and service quality in the public sector. Research into the practice at all levels of government has been expanding for decades in developed countries. However, the small local governments that comprise most U.S. municipalities are frequently overlooked as a topic of academic inquiry in public administration. This study aims to shed light on the extent to which the performance measurement methods prevalent at the state and federal levels have spread to small municipalities. Using elite interviewing methods and the four-point approach to …
An Adversarial Framework For Deep 3d Target Template Generation, Walter E. Waldow
An Adversarial Framework For Deep 3d Target Template Generation, Walter E. Waldow
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This paper presents a framework for the generation of 3D models. This is an important problem for many reasons. For example, 3D models are important for systems that are involved in target recognition. These systems use 3D models to train up accuracy on identifying real world object. Traditional means of gathering 3D models have limitations that the generation of 3D models can help overcome. The framework uses a novel generative adversarial network (GAN) that learns latent representations of two dimensional views of a model to bootstrap the network’s ability to learn to generate three dimensional objects. The novel architecture is …
Alternative Splicing Of Mdm4 In Human Melanomas, Abdullah Salem S. Alatawi
Alternative Splicing Of Mdm4 In Human Melanomas, Abdullah Salem S. Alatawi
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Melanoma is a potentially lethal type of skin cancer and regarded to be the third most common type of skin cancer. Although melanoma is not as common as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), it is more likely to metastasize than BCC and SCC. Interestingly, the incidence of melanoma continues to go up (expected 2% in 2020), but the deaths continue to decrease (-5.3% in 2020) due to improvements in detection and treatment. The treatment of melanoma depends on several aspects but most importantly the tumor's stage and the location. In the early stages, melanoma can be …
Adaptive Multi-Fidelity Modeling For Efficient Design Exploration Under Uncertainty, Atticus J. Beachy
Adaptive Multi-Fidelity Modeling For Efficient Design Exploration Under Uncertainty, Atticus J. Beachy
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This thesis work introduces a novel multi-fidelity modeling framework, which is designed to address the practical challenges encountered in Aerospace vehicle design when 1) multiple low-fidelity models exist, 2) each low-fidelity model may only be correlated with the high-fidelity model in part of the design domain, and 3) models may contain noise or uncertainty. The proposed approach approximates a high-fidelity model by consolidating multiple low-fidelity models using the localized Galerkin formulation. Also, two adaptive sampling methods are developed to efficiently construct an accurate model. The first acquisition formulation, expected effectiveness, searches for the global optimum and is useful for modeling …
Evolution Of Electron Properties After Nanosecond Repetitively Pulsed Discharges In Air Measured By Thomson Scattering, Chase S. Murray
Evolution Of Electron Properties After Nanosecond Repetitively Pulsed Discharges In Air Measured By Thomson Scattering, Chase S. Murray
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This work was an investigation of nanosecond repetitively pulsed discharges in air by measuring the evolution of electron density and electron temperature between pulses using Thomson scattering of laser light. Bursts of repetitive pulses within several microseconds after the initial pulse were found to exhibit a coupling effect and create an even higher electron density than the initial pulse. The wide range of temperatures and densities of the electrons existing between pulses allow an opportunity to explore both the collective and non-collective regimes of Thomson scattering. By measuring electron density and temperature at a variety of times, an accurate description …