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Benzimidazole Adjuvant Therapy: A Review Of Efficacy And Safety In Patients With Cancer, Jared Mouw
Benzimidazole Adjuvant Therapy: A Review Of Efficacy And Safety In Patients With Cancer, Jared Mouw
Physician Assistant Scholarly Project Papers
This literature review aims to compile previous studies’ data and explore the effects of benzimidazoles as an adjuvant therapy and its relationship to a patient’s cancer biomarkers, tumor progression, and quality of life. In addition to the aforementioned, we will attempt to review data to identify the safety and toxicity profile of benzimidazoles within a population of patients currently diagnosed with cancer to determine if this class of medications could be implemented along with current cancer treatment regimens to increase efficacy and tolerance. To determine this, the databases of CINAHL, ClinicalKey, and PubMed were searched with the keywords mentioned below. …
A Comparison Of Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies And Standard Migraine Prophylaxis In Those With Episodic Migraines, Alexie Harms
Physician Assistant Scholarly Project Papers
The purpose of this research study is to determine if anti-calcitonin gene related peptide monoclonal antibodies (CGRP mAbs) more effective and tolerable in reducing the number of migraine days in comparison to conventional migraine prophylactic use of Propranolol, Amitriptyline, and Topiramate. Migraines are debilitating and a frequent reason for primary care visits interfering with an individual’s work, school, and daily life. Standard of care treatment options for migraine prophylaxis are drugs initially developed for other diseases and can lead to unnecessary and unwanted side effects decreasing treatment adherence in the prevention of migraines. In this literature review, electronic search databases …
Effectiveness Of Knee Joint Injury Treatments In The Prevention Of Post-Traumatic Osteoarthritis, Jenna Zaeske
Effectiveness Of Knee Joint Injury Treatments In The Prevention Of Post-Traumatic Osteoarthritis, Jenna Zaeske
Physician Assistant Scholarly Project Papers
The purpose of this research and systematic literature review is to determine the effectiveness of rest, physical therapy, and/or surgical intervention following either anterior cruciate ligament (ACL) or meniscus injuries in short- and long- term osteoarthritis outcomes. The short- and longterm outcomes were evaluated to compare the prevalence and progression of osteoarthritis after joint injury. In this literature review, the electronic database PubMed was used to find relevant research. Many keywords were used when searching for articles. Sources included for review had research on ACL or meniscus injuries specifically. Other knee injuries, non-knee injuries and non-human subjects were excluded. Articles …
The Effects Of Food On Mood: Implications Of Mediterranean And Plant-Based Diets On Depression Symptom Prevalence And Severity, Kaitlyn Prochnow
The Effects Of Food On Mood: Implications Of Mediterranean And Plant-Based Diets On Depression Symptom Prevalence And Severity, Kaitlyn Prochnow
Physician Assistant Scholarly Project Papers
The purpose of this research and systematic literature review is to determine whether adherence to a Mediterranean diet or a plant-based diet has better effects on decreasing depression prevalence and/or symptom severity. A variety of keywords were used to search the online database, PubMed. Clinical trials and randomized controlled trials conducted within the last 20 years were included in the initial search. Exclusions were made if studies were not specific to Mediterranean or plant-based diets, or if they were focused on other psychiatric illnesses besides depression. For the final review, ten articles were selected. After thorough analyses and comparisons of …
Aspirin Vs. Pravastatin For Prevention Of Preterm Delivery In Patients At Risk For Pre-Eclampsia, Mary Weisberg
Aspirin Vs. Pravastatin For Prevention Of Preterm Delivery In Patients At Risk For Pre-Eclampsia, Mary Weisberg
Physician Assistant Scholarly Project Papers
This literature review is an examination of the use of low-dose aspirin therapy versus the use of pravastatin therapy to prevent preterm delivery in women at risk of developing preeclampsia. Preeclampsia is defined as new onset hypertension after 20 weeks of gestation with evidence of maternal organ or uteroplacental dysfunction or proteinuria. Preeclampsia is a serious condition that affects pregnant women and their growing fetuses which may lead to maternal or fetal demise. The Prevention of preeclampsia with the use of low-dose aspirin in the first 12-16 weeks is currently the mainstay of treatment for women with moderate to severe …
Long-Term Control Of Type Ii Diabetes Mellitus And Weight Through Roux-En-Y Gastric Bypass Surgery Versus Weight Loss Medication, Alexandra Laber
Long-Term Control Of Type Ii Diabetes Mellitus And Weight Through Roux-En-Y Gastric Bypass Surgery Versus Weight Loss Medication, Alexandra Laber
Physician Assistant Scholarly Project Papers
Type II diabetes mellitus (T2DM) affects hundreds of millions of individuals in the United States and is only becoming more common. The disease can damage organs all throughout the body and even lead to death. The goal of treatment is to lower blood glucose, but since T2DM tends to be associated with obesity, another common goal in treatment is weight loss. However, this is difficult for many people to achieve, and intense medical treatment is sometimes needed. Since T2DM is a lifelong disease, interventions must be considered in the long term. The purpose of this project is to compare long-term …
Home-Based Cardiac Rehab Vs. Center-Based Cardiac Rehab In Rural Areas, Timothy Fresonke
Home-Based Cardiac Rehab Vs. Center-Based Cardiac Rehab In Rural Areas, Timothy Fresonke
Physician Assistant Scholarly Project Papers
Cardiac rehabilitation in rural areas can present unique challenges. The main challenge is the locations patients must travel to receive such care. Some patients are expected to travel more then an hour away, on multiple occasions during the week, to undergo therapy. This can be an issue for many patients and something that has been studied and is starting to be addressed in various countries. A literature review was done to see if there was a safe and effective alternative to the traditional center-based cardiac rehabilitation. The electronic search databases PubMed, Embase and CINAHL Complete were utilized to search for …
The Effect Of Metformin Vs Lifestyle Modifications On The Prevention Of Prediabetes Progressing To Type Ii Diabetes, Brittany Mcpherson
The Effect Of Metformin Vs Lifestyle Modifications On The Prevention Of Prediabetes Progressing To Type Ii Diabetes, Brittany Mcpherson
Physician Assistant Scholarly Project Papers
Prediabetes is a common disease among American adults that is the predecessor to type 2 diabetes (T2D). T2D is a serious disease that causes long term damage to the heart, blood vessels, and kidneys if uncontrolled. This literature review looks at the effectiveness of medication (metformin), diet alone, exercise alone, and diet and exercise in combination in preventing the progression from prediabetes to a diagnosis of T2D. The literature review was performed using an electronic search database to identify literature related to preventing the conversion of prediabetes to T2D using either lifestyle modifications or metformin within the past five years. …
Cognitive Behavior Therapy Versus Internet Cognitive Behavior Therapy In Adults With Anxiety Or Depression, Heather Greenwood
Cognitive Behavior Therapy Versus Internet Cognitive Behavior Therapy In Adults With Anxiety Or Depression, Heather Greenwood
Physician Assistant Scholarly Project Papers
According to the American Psychiatric Association, the prevalence of anxiety and depression in adults in their lifetime are nearly 30% and 16.6% respectively. The combination of pharmacotherapy and psychotherapy interventions (including talk therapy or cognitive behavior therapy (CBT)) are considered best practice, but in recent years there has been an increase in the popularity of applications and web-based services categorized as “internet cognitive behavior therapy”, or ICBT. The question proposed is, are these services as good for patient outcomes as traditional in-person CBT? A literature review was performed using electronic medical database PubMed with key word searches for cognitive behavior …
Impact Of Circadian Rhythm On Attention-Deficit Hyperactivity Disorder, Tyson Williams
Impact Of Circadian Rhythm On Attention-Deficit Hyperactivity Disorder, Tyson Williams
Physician Assistant Scholarly Project Papers
The purpose of this research and systematic literature review is to determine if altering the circadian rhythm in people with Attention-Deficit Hyperactivity Disorder (ADHD) improves their symptoms. Up to 75% of people with childhood-onset ADHD exhibit a delayed circadian rhythm phase. This can cause difficulty in initiating and maintaining sleep, which in turn can cause excessive daytime sleepiness and further exacerbate ADHD symptoms, especially hyperactivity. Journal articles were searched in the databases of PubMed that concerned treatment aspects that would affect circadian rhythm and ADHD. Topics were further divided into themes that included melatonin, light therapy (LT), sleep hygiene intervention, …
The Role Of Occupational Therapy In Determining The Effectiveness Of Functional Task Assessments Used To Improve Quality Of Life For Older Adults With Parkinson’S Disease., Kate L. Westphal, Brooklyn L. Wiest, Jordyn M. Wolff
The Role Of Occupational Therapy In Determining The Effectiveness Of Functional Task Assessments Used To Improve Quality Of Life For Older Adults With Parkinson’S Disease., Kate L. Westphal, Brooklyn L. Wiest, Jordyn M. Wolff
Critically Appraised Topics
This critically appraised topic focuses on the role of occupational therapy in ascertaining the effectiveness of specific functional assessments in improving the quality of life of older adults with Parkinson’s disease.
Associations Between Social Media And Mood, Madison Connors
Associations Between Social Media And Mood, Madison Connors
Undergraduate Theses and Senior Projects
Since its emergence, social media has evolved quickly and to become more widespread year by year (Pew Research Center, 2021). Along with the steady increase of social media use, there has also been a steady increase in depression in the United States, especially in those aged 12-17 (Mental Health America, 2022). This purpose of this study was to examine the relationship between social media and mental health by replicating a study conducted by Shensa and colleagues (2017) that investigated the relationship between social media use and depression in U.S. young adults, but also to include measures of fear of missing …
Effects Of Occupation Based Interventions Related To Play And Leisure For Minimization Of Post-Concussion Or Mild Traumatic Brain Injury Symptoms In Adolescents: A Critically Appraised Topic, Anneka Harris, Melody Mackenzie, Emmy Miller
Effects Of Occupation Based Interventions Related To Play And Leisure For Minimization Of Post-Concussion Or Mild Traumatic Brain Injury Symptoms In Adolescents: A Critically Appraised Topic, Anneka Harris, Melody Mackenzie, Emmy Miller
Critically Appraised Topics
Occupational therapy has a vital impact on healthcare providing a holistic approach to care with the goal of improving quality of life, increasing participation in meaningful occupations, and speeding up the recovery process for a variety of health conditions. In concussion management, occupational therapy professionals play a critical role on the multidisciplinary team, understanding the important interaction between the athlete, occupation, and the environment (Andreas et al., 2021). Even though the target population for this critically appraised topic (CAT) is adolescents, athletes (those who experienced a sports-related concussion) comprise most of the studies due to the prevalence of sports-related concussions. …
Exploring Occupation-Based Sleep Interventions For School-Aged Children Experiencing Homelessness: A Critically Appraised Topic, Aspen Delano, Joslynn Sauer, Emily Vieth
Exploring Occupation-Based Sleep Interventions For School-Aged Children Experiencing Homelessness: A Critically Appraised Topic, Aspen Delano, Joslynn Sauer, Emily Vieth
Critically Appraised Topics
Sleep is a crucial component of healthy neurological development throughout childhood. According to Suni (2023a), elementary school-aged children between the ages of 6 and 12 experience sleep deprivation when they obtain less than 9 hours of sleep per night. Contie (2022) found that children experiencing insufficient sleep had more mental health and behavioral challenges than those who had sufficient sleep. Additionally, Contie (2022) found that children experiencing sleep deprivation had less gray matter and volume in their brains. This impacts cognitive functioning, specifically decision-making, conflict-solving, working memory, and learning. The brain undergoes critical development of the basal ganglia, ganglia-thalamus-cortex circuit, …
Cat Part Iv: Occupational Therapy Interventions To Support Upper Extremity Spasticity In Older Adults Following A Stroke, Mary Redlin, Allie Reiffenberger, Shannon Ring, Aubrey Rude
Cat Part Iv: Occupational Therapy Interventions To Support Upper Extremity Spasticity In Older Adults Following A Stroke, Mary Redlin, Allie Reiffenberger, Shannon Ring, Aubrey Rude
Critically Appraised Topics
This critically appraised topic focuses on interventions for improving hand functions in activities of daily living (ADLs) for elderly adults who have chronic upper extremity spasticity following a stroke. For the purpose of this critically appraised topic, the focus will be on the elderly population, defined as being age 55 and older; research indicates stroke is most prevalent in this population (Mayo Clinic, 2022). When considering a particular theory, the Ecology of Human Performance (EHP) is the most suitable model for our focus question (Dunn, 2017). The Ecology of Human Performance is focused on the person and environment to increase …
Effectiveness Of Occupational Therapy’S Role In Promotion Of Role Fulfillment With Aviation Students In Higher Education Who Are Experiencing Mental Health Conditions, Payton O. Schilke, Olivia G. Schoffstall, Lexi K. Smith, Gracie J. Stimac
Effectiveness Of Occupational Therapy’S Role In Promotion Of Role Fulfillment With Aviation Students In Higher Education Who Are Experiencing Mental Health Conditions, Payton O. Schilke, Olivia G. Schoffstall, Lexi K. Smith, Gracie J. Stimac
Critically Appraised Topics
This critically appraised topic paper focuses on occupational therapy’s role and the interventions for improving the mental health of aviation students in higher education. Aviation students are higher education student pilots learning to become pilots within various roles. Stress and fatigue among students in higher education are prominent problems (Beiter, 2015; Kalmakis et al., 2021). The focus on aviation students for this critically appraised topic paper reveals the unique stressors relating to flight training that is added on top of the normal academic stress load that university students face (Robertson & Ruiz, 2010). Due to these stress factors, the mental …
Occupational Therapy’S Role In Natural Disasters, Olivia A. Dobrinz, Elise N. Gapp, Jocelyn R. Kirk
Occupational Therapy’S Role In Natural Disasters, Olivia A. Dobrinz, Elise N. Gapp, Jocelyn R. Kirk
Critically Appraised Topics
This critically appraised topic paper (CAT) focuses on interventions for improving individuals’ quality of life and occupational participation following a natural disaster. Described within this CAT are the impacts on individual’s occupations following a natural disaster, the quality of life for individuals, and occupational therapy’s role in improving an individual’s quality of life and occupational participation.
Occupational Therapy’S Role In Addressing The Intersectionality Of Veterans Who Are Chronically Homeless, Mental Health, And Sleep Deprivation, Maci Bakken, Abby Eken, Morgan Halliday
Occupational Therapy’S Role In Addressing The Intersectionality Of Veterans Who Are Chronically Homeless, Mental Health, And Sleep Deprivation, Maci Bakken, Abby Eken, Morgan Halliday
Critically Appraised Topics
Currently, there are interventions available for rest and sleep for the general population. However, those interventions do not usually address the unique needs of the population of veterans who are homeless with mental health disorders. While there is information on the person, environmental, and occupational factors surrounding this topic separately, there is limited literature regarding how to address all of these factors when they transact with each other. The purpose of this critically appraised topic paper is to examine the impacts that being a veteran, having a mental health disorder, and being homeless have on sleep deprivation as well as …
Increasing Parent Confidence And Involvement In The Nicu: An Occupational Therapy Educational Guide, Megan D. Berginski
Increasing Parent Confidence And Involvement In The Nicu: An Occupational Therapy Educational Guide, Megan D. Berginski
Occupational Therapy Capstones
Research shows that 40% of mothers with preterm infants in the neonatal intensive care unit (NICU) reported feelings of depression, and 23% reported experiencing post-traumatic stress symptoms, with that number increasing to 40% after discharge (Harris et al., 2018). Factors that contributed to this included a lack of social support, a lack of empowerment, perceived less capability in their new roles, and the stressful experiences that can happen in this setting (Matricardi et al., 2013; Sabnis et al., 2019). A similar study found that at discharge, 69.8% of parents reported that they were not confident in providing the necessary care …
Let’S Groove: A Dance Program Designed For Children With Disabilities, Michayla Burckhard
Let’S Groove: A Dance Program Designed For Children With Disabilities, Michayla Burckhard
Occupational Therapy Capstones
Children with disabilities face limited opportunities to participate in the occupation of dance when compared to opportunities available for their non-disabled peers. Barriers to their participation include lack of class opportunities, cost, and knowledge about programs (Carrion et al., 2018). Many dance studios offer integrated or non-specialized classes, but participation by a child with a disability in this type of class is sometimes limited by parental or child fears, or other barriers such as lack of accommodations (Lucas, 2017).
Addressing Adherence To Home Exercise Programs In A Hand Therapy Setting, Austin B. Ellis
Addressing Adherence To Home Exercise Programs In A Hand Therapy Setting, Austin B. Ellis
Occupational Therapy Capstones
Roughly 1,100 per 100,000 persons experience an upper-extremity injury per year including burns, fractures, or amputations (Ootes et al., 2012). These upper-extremity injuries can impact a person’s physical function, activities of daily living (ADL), social, psychological, and financial aspects in life (Che Daud et al., 2016b). These statistics warrant the need for occupational therapy practitioners specializing in hand therapy, and other hand therapists to address these areas of client’s lives that have been affected by their upper extremity injury.
Supporting Caregivers Of Children With Complex Health Needs, Anne Louise Domanus
Supporting Caregivers Of Children With Complex Health Needs, Anne Louise Domanus
Occupational Therapy Capstones
The purpose of this scholarly project is to develop and implement programming that provides support and meets the needs of caregivers of children with complex health needs. This was done by providing a resource guide of local community resources to caregivers to increase engagement in leisure occupations.
Exploring Nature-Based And Animal-Assisted Therapies As A Therapeutic Modality, Rachel Cheatley
Exploring Nature-Based And Animal-Assisted Therapies As A Therapeutic Modality, Rachel Cheatley
Occupational Therapy Capstones
Animal-assisted therapy (AAT) is characterized by integrating animals into the therapy process as a therapeutic partner and modality (Laskowski et. al., 2019). AAT shows positive outcomes for those who take part in the practice (Ein et. al., 2018; Feng et. al., 2021; Mapes & Rosén, 2016; Nieforth et. al., 2021). Common goals that are targeted via AAT include anxiety and related symptoms, depression and related symptoms, coordination, fine motor skills, reaching, hand-eye coordination, body balance, body awareness, communication, and relationship building (Ein et. al., 2018; Feng et. al., 2021; Mapes & Rosén, 2016; Nieforth et. al., 2021). Even with the …
The Effects Of Sensory Exposures On Pre-Term Infants Within The Neonatal Intensive Care Unit, Isabell Grace Fetsch
The Effects Of Sensory Exposures On Pre-Term Infants Within The Neonatal Intensive Care Unit, Isabell Grace Fetsch
Occupational Therapy Capstones
The neonatal intensive care unit (NICU) setting is a very dynamic, complex environment that can greatly affect the well-being and physical development of pre-term infants. Pre-term infants are defined as infants born earlier than 37 weeks’ gestation (CDC, 2021). AOTA (2018) researchers stated that a pre-term infant does not have the self-regulatory tools to adapt to the complex and highly stressful NICU environment. Pineda et al. (2017) explained that the environment within the NICU presents many adverse sensory stimuli such as bright lights, loud noises, and stressful human touches. When infants are unable to manage environmental sensory exposures appropriately due …
Caring For All In The Nicu, Zachary Daniel Gascho
Caring For All In The Nicu, Zachary Daniel Gascho
Occupational Therapy Capstones
In the neonatal intensive care unit (NICU), the infants who are being examined, evaluated, and treated are not the only people that need to be thought of when providing care. The parents/guardians in the NICU are just as important to consider in providing support. Research has shown that parents who have a child in the NICU experience a great deal of stress and guidelines recommend emotional support intervention in the NICU (Bigsby, 2021; Dudek-Shriber, 2004, Hynan & Hall, 2015). Emotional support is needed for these parents as they are experiencing perinatal mood and anxiety disorders that are often left untreated …
The Mind Matters: Interprofessional Mental And Emotional Health Guide For Cancer Survivors, Jaecy Giegerich
The Mind Matters: Interprofessional Mental And Emotional Health Guide For Cancer Survivors, Jaecy Giegerich
Occupational Therapy Capstones
Cancer is the second-highest leading cause of death in the United States with approximately 1.9 million new cancer cases and over 600,000 deaths in 2022 alone (Department of Health and Human Services et al., 2022). Cancer-related mental health is a primary barrier for engagement in treatment-related care; negatively impacting survivors’ perceived quality of life (Islam et al., 2022). Comprised mental health is one of the contributing factors to suicide. Patients undergoing a cancer diagnosis are at an ever-high suicide risk with incidences higher than other diagnoses (Saad et al., 2019).
Educating The Educator: Articulating Ot’S Role In School-Based Collaboration, Bryce Shaun Graves
Educating The Educator: Articulating Ot’S Role In School-Based Collaboration, Bryce Shaun Graves
Occupational Therapy Capstones
Many teachers in the educational field are unaware of the role of occupational therapists (OTs) and how OTs can support teachers and students (Kennedy et al., 2018; Truong & Hodgetts, 2017). Educators who are aware of the OT role often desire further collaboration including realistic recommendations for their classroom (Truong & Hodgetts, 2017). This presents a need for increased education about the role of occupational therapy (OT) in school-based practice and additional instruction for increased effectiveness of OT-teacher collaboration.
Fostering A Loving Connection: A Foster Parent’S Toolkit For Understanding And Addressing Behaviors For Children Placed In Out-Of-Home Care, Emily A. Knust
Fostering A Loving Connection: A Foster Parent’S Toolkit For Understanding And Addressing Behaviors For Children Placed In Out-Of-Home Care, Emily A. Knust
Occupational Therapy Capstones
Children placed in out-of-home care have an 80% chance of having a mental health diagnosis or experiencing negative behaviors related to trauma experiences (Armstrong-Hiemsoth et al., 2020). Children in foster care have been exposed to trauma by being removed from their biological parents and the abuse, neglect, or unsafe conditions that occurred leading up to the removal and placement in out-of-home care (Bartlett, 2021). From this trauma, a child is more likely to experience difficulty with basic self-care skills, executive functioning, emotional regulation, attachment disorders, or positive interactions and relationships within the foster home and their environment (Pervis et al., …
Primitive Reflex Screening And Caregiver Education And Support. A Product To Support Children With Retained Primitive Reflexes Transitioning Into The Formal Education System., Anna Justine Logan
Primitive Reflex Screening And Caregiver Education And Support. A Product To Support Children With Retained Primitive Reflexes Transitioning Into The Formal Education System., Anna Justine Logan
Occupational Therapy Capstones
Infants are born with movement patterns called primitive reflexes. Primitive reflexes are active for approximate times during the first few years of life (Smet et al, 2020; Myott et al., 2016). Retained primitive reflexes are primitive reflexes that have not integrated in the expected time. Retained primitive reflexes have been linked to a variety of developmental delays in older children including fine and gross motor (Gieysztor et al., 2018a), visual (Andrich et al., 2018), and academic performance (Feldhacker et al., 2021; Calvin & Ramli, 2020).
Development Of A School Based Program: Implementing Occupational Therapy Into General Education Classrooms, Samantha Jo Larson
Development Of A School Based Program: Implementing Occupational Therapy Into General Education Classrooms, Samantha Jo Larson
Occupational Therapy Capstones
The purpose of this scholarly project (SP) was to build a program containing activities for kindergarten and first grade general education classrooms that promote childrens’ skills that are necessary for development in handwriting, reading, writing, spelling, and clothing management.