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Michigan Technological University

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2019

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Reply To Commentary By R Duggleby (2019), Edward J. Steele, Shirwan Al-Mufti, Kenneth Augustyn, Rohana Chandrajith, John P. Coghlan, S. G. Coulson, Et Al. Jan 2019

Reply To Commentary By R Duggleby (2019), Edward J. Steele, Shirwan Al-Mufti, Kenneth Augustyn, Rohana Chandrajith, John P. Coghlan, S. G. Coulson, Et Al.

Michigan Tech Publications

No abstract provided.


Engineering Stem Cell Cardiac Patch With Microvascular Features Representative Of Native Myocardium, Zichen Qian, Dhavan Sharma, Wenkai Jia, Daniel Radke, Timothy Kamp, Feng Zhao Jan 2019

Engineering Stem Cell Cardiac Patch With Microvascular Features Representative Of Native Myocardium, Zichen Qian, Dhavan Sharma, Wenkai Jia, Daniel Radke, Timothy Kamp, Feng Zhao

Michigan Tech Publications

The natural myocardium is a highly aligned tissue with an oriented vasculature. Its characteristic cellular as well as nanoscale extracellular matrix (ECM) organization along with an oriented vascular network ensures appropriate blood supply and functional performance. Although significant efforts have been made to develop anisotropic cardiac structure, currently neither an ideal biomaterial nor an effective vascularization strategy to engineer oriented and high-density capillary-like microvessels has been achieved for clinical cardiovascular therapies. A naturally derived oriented ECM nanofibrous scaffold mimics the physiological structure and components of tissue ECM and guides neovascular network formation. The objective of this study was to create …


Introduction To The Second Special Issue On Biological Mentality, Kenneth Augustyn Jan 2019

Introduction To The Second Special Issue On Biological Mentality, Kenneth Augustyn

Michigan Tech Publications

No abstract provided.


Physical Foundations Of Biological Mentality, Kenneth Augustyn Jan 2019

Physical Foundations Of Biological Mentality, Kenneth Augustyn

Michigan Tech Publications

Dualism struggles to connect two layers: the conscious mind and the physical workings of matter. It ignores a vast middle layer between the two, a layer that is beneath consciousness yet above known physical law. This middle layer is trans-robotic mentality, a means discovered by Nature to transcend robotic mentality. This middle layer evolved over billions of years before consciousness emerged from it, assuming more and more functions critical to survival as species evolved. Consciousness eventually emerged from trans-robotic mentality (not from robotic mentality), first intermittently then later more-or-less continuously. But there is no direct link between consciousness and matter. …


Maia: A Language For Mandatory Integrity Controls Of Structured Data, Wassnaa Al-Mawee, Paul Bonamy, Steven Carr, Jean Mayo Jan 2019

Maia: A Language For Mandatory Integrity Controls Of Structured Data, Wassnaa Al-Mawee, Paul Bonamy, Steven Carr, Jean Mayo

Michigan Tech Publications

The integrity of systems files is necessary for the secure functioning of an operating system. Integrity is not generally discussed in terms of complete computer systems. Instead, integrity issues tend to be either tightly coupled to a particular domain (e.g. database constraints), or else so broad as to be useless except after the fact (e.g. backups). Often, file integrity is determined by who modifies the file or by a checksum. This paper focuses on a general model of the internal integrity of a file. Even if a file is modified by a subject with trust or has a valid checksum, …


Unconventional Oil And Gas Energy Systems: An Unidentified Hotspot Of Antimicrobial Resistance?, Maria Fernanda Campa, Amy K Wolfe, Stephen Techtmann, Ann-Marie Harik, Terry C Hazen Jan 2019

Unconventional Oil And Gas Energy Systems: An Unidentified Hotspot Of Antimicrobial Resistance?, Maria Fernanda Campa, Amy K Wolfe, Stephen Techtmann, Ann-Marie Harik, Terry C Hazen

Michigan Tech Publications

Biocides used in unconventional oil and gas (UOG) practices, such as hydraulic fracturing, control microbial growth. Unwanted microbial growth can cause gas souring, pipeline clogging, and microbial-induced corrosion of equipment and transportation pipes. However, optimizing biocide use has not been a priority. Moreover, biocide efficacy has been questioned because microbial surveys show an active microbial community in hydraulic fracturing produced and flowback water. Hydraulic fracturing produced and flowback water increases risks to surface aquifers and rivers/lakes near the UOG operations compared with conventional oil and gas operations. While some biocides and biocide degradation products have been highlighted as chemicals of …


A Gene Based Approach To Test Genetic Association Based On An Optimally Weighted Combination Of Multiple Traits., Jianjun Zhang, Qiuying Sha, Guanfu Liu, Xuexia Wang Jan 2019

A Gene Based Approach To Test Genetic Association Based On An Optimally Weighted Combination Of Multiple Traits., Jianjun Zhang, Qiuying Sha, Guanfu Liu, Xuexia Wang

Michigan Tech Publications

There is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases for which multiple correlated traits are often measured. Joint analysis of multiple traits could increase statistical power by aggregating multiple weak effects. Existing methods for multiple trait association tests usually study each of the multiple traits separately and then combine the univariate test statistics or combine p-values of the univariate tests for identifying disease associated genetic variants. However, ignoring correlation between phenotypes may cause power loss. Additionally, the genetic variants in one gene (including common and rare variants) are often viewed as a whole that affects …


Studies Of The Time Structure Of Extended Air Showers For Direction Reconstruction With The Hawc Outrigger Array, Dezhi Huang Jan 2019

Studies Of The Time Structure Of Extended Air Showers For Direction Reconstruction With The Hawc Outrigger Array, Dezhi Huang

Michigan Tech Publications

The High Altitude Water Cherenkov (HAWC) gamma-ray observatory is a ground-based air shower array designed to detect Cherenkov light produced in water by secondary particles from atmospheric air showers. In order to improve the sensitivity at the highest energies, especially for the shower cores falling outside the main array, 345 smaller Water Cherenkov Detectors (WCDs) were installed around the main array, the outrigger array. This extension increased the instrumented area of HAWC by a factor of four. With the increased size of the array, and the ability to detect shower particles further away from the core, understanding of the time …


Electron Spectrum Of The Dragonfly Pulsar Wind Nebula From X-Ray To Tev, Chad Brisbois, V. Joshi Jan 2019

Electron Spectrum Of The Dragonfly Pulsar Wind Nebula From X-Ray To Tev, Chad Brisbois, V. Joshi

Michigan Tech Publications

The Dragonfly nebula is a Vela-like Pulsar Wind Nebula (PWN) in the Cygnus region powered by the spin down of PSR J2021+3651. In X-rays, the inner nebula is a few arcseconds across, whereas at TeV energies VERITAS and HAWC has observed extended emission much larger than the extension in X-rays. The TeV gamma-ray source HAWC J2019+368 was originally discovered in 2007 by the Milagro Observatory and has been associated with this pulsar. Recent work has shown hints of energy dependent morphology for the source at TeV energies, supporting the interpretation of the gamma-ray emission being due to Inverse Compton scattering …