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Antibacterial Properties Of Mussel-Inspired Polydopamine Coatings Prepared By A Simple Two-Step Shaking-Assisted Method, Pegah Kord Fooroshani, Elizabeth Polega, Kevin Thomson, Mohammad Saleh Akram Bhuiyan, Rattapol Pinnaratip, Mikhail Trought, Chito E. Kendrick, Yuesheng Gao, Kahryn Perrine, Lei Pan, Bruce P. Lee Sep 2019

Antibacterial Properties Of Mussel-Inspired Polydopamine Coatings Prepared By A Simple Two-Step Shaking-Assisted Method, Pegah Kord Fooroshani, Elizabeth Polega, Kevin Thomson, Mohammad Saleh Akram Bhuiyan, Rattapol Pinnaratip, Mikhail Trought, Chito E. Kendrick, Yuesheng Gao, Kahryn Perrine, Lei Pan, Bruce P. Lee

Michigan Tech Publications

A simple two-step, shaking-assisted polydopamine (PDA) coating technique was used to impart polypropylene (PP) mesh with antimicrobial properties. In this modified method, a relatively large concentration of dopamine (20 mg ml−1) was first used to create a stable PDA primer layer, while the second step utilized a significantly lower concentration of dopamine (2 mg ml−1) to promote the formation and deposition of large aggregates of PDA nanoparticles. Gentle shaking (70 rpm) was employed to increase the deposition of PDA nanoparticle aggregates and the formation of a thicker PDA coating with nano-scaled surface roughness (RMS = 110 …


Development And Characterization Of An Antimicrobial Polydopamine Coating For Conservation Of Humpback Whales., Ariana Tyo, Sonja Welch, Maureen Hennenfent, Pegah Kord Fooroshani, Bruce P Lee, Rupak Rajachar Sep 2019

Development And Characterization Of An Antimicrobial Polydopamine Coating For Conservation Of Humpback Whales., Ariana Tyo, Sonja Welch, Maureen Hennenfent, Pegah Kord Fooroshani, Bruce P Lee, Rupak Rajachar

Michigan Tech Publications

Migration patterns of humpback whales have been monitored using 316L stainless steel (SS) satellite telemetry tags. The potential for tissue infection and necrosis is increased if the bacteria, naturally a part of the diverse microbiome on the skin of humpback whales, can adhere to and colonize the surface of the tags. Polydopamine (pDA) has the potential to prevent the adhesion of one of the most prevalent bacterial strains on the surface of the skin of cetaceans (


Multi-Functional Electrospun Nanofibers From Polymer Blends For Scaffold Tissue Engineering, Samerender Nagam Hanumantharao, Smitha Rao Jul 2019

Multi-Functional Electrospun Nanofibers From Polymer Blends For Scaffold Tissue Engineering, Samerender Nagam Hanumantharao, Smitha Rao

Michigan Tech Publications

Electrospinning and polymer blending have been the focus of research and the industry for their versatility, scalability, and potential applications across many different fields. In tissue engineering, nanofiber scaffolds composed of natural fibers, synthetic fibers, or a mixture of both have been reported. This review reports recent advances in polymer blended scaffolds for tissue engineering and the fabrication of functional scaffolds by electrospinning. A brief theory of electrospinning and the general setup as well as modifications used are presented. Polymer blends, including blends with natural polymers, synthetic polymers, mixture of natural and synthetic polymers, and nanofiller systems, are discussed in …


Accelerating 3-D Gpu-Based Motion Tracking For Ultrasound Strain Elastography Using Sum-Tables: Analysis And Initial Results., Bo Peng, Shasha Luo, Zhengqiu Xu, Jingfeng Jiang May 2019

Accelerating 3-D Gpu-Based Motion Tracking For Ultrasound Strain Elastography Using Sum-Tables: Analysis And Initial Results., Bo Peng, Shasha Luo, Zhengqiu Xu, Jingfeng Jiang

Michigan Tech Publications

Now, with the availability of 3-D ultrasound data, a lot of research efforts are being devoted to developing 3-D ultrasound strain elastography (USE) systems. Because 3-D motion tracking, a core component in any 3-D USE system, is computationally intensive, a lot of efforts are under way to accelerate 3-D motion tracking. In the literature, the concept of Sum-Table has been used in a serial computing environment to reduce the burden of computing signal correlation, which is the single most computationally intensive component in 3-D motion tracking. In this study, parallel programming using graphics processing units (GPU) is used in conjunction …


Engineering Stem Cell Cardiac Patch With Microvascular Features Representative Of Native Myocardium, Zichen Qian, Dhavan Sharma, Wenkai Jia, Daniel Radke, Timothy Kamp, Feng Zhao Jan 2019

Engineering Stem Cell Cardiac Patch With Microvascular Features Representative Of Native Myocardium, Zichen Qian, Dhavan Sharma, Wenkai Jia, Daniel Radke, Timothy Kamp, Feng Zhao

Michigan Tech Publications

The natural myocardium is a highly aligned tissue with an oriented vasculature. Its characteristic cellular as well as nanoscale extracellular matrix (ECM) organization along with an oriented vascular network ensures appropriate blood supply and functional performance. Although significant efforts have been made to develop anisotropic cardiac structure, currently neither an ideal biomaterial nor an effective vascularization strategy to engineer oriented and high-density capillary-like microvessels has been achieved for clinical cardiovascular therapies. A naturally derived oriented ECM nanofibrous scaffold mimics the physiological structure and components of tissue ECM and guides neovascular network formation. The objective of this study was to create …