Digital Commons Network^™

The Role Of Gli3 In Inflammation, Stephan Josef Matissek

Doctoral Dissertations

Inflammation is an important and healthy mechanism that our body uses for wound-healing and fighting off infections by utilizing molecular pathways of immune and non-immune cells. However, when inflammation is persistent or chronic it can have severe consequences that can lead to auto-immune diseases or cancer. Pathogen-associated molecular patterns (PAMPs), such as Lipopolysaccharide (LPS), present on gramnegative bacteria, or double-stranded RNA (dsRNA), present in RNA-viruses, were shown to be potent inducers of inflammation. These PAMPs are known ligands of Toll like receptor 4 (TLR4), activated by LPS and Toll-like receptor 3 (TLR3), activated by dsRNA which are carried on the …

Utilizing Extended Continental Shelf (Ecs) And Ocean Exploration Mapping Data For Standardized Marine Ecological Classification Of The U.S. Atlantic Margin, Derek C. Sowers

Doctoral Dissertations

Accurate maps of ocean bathymetry and seafloor habitats are needed to support effective marine ecosystem-based management (EBM) approaches. The central premise of this thesis was to synthesize geomorphological elements of large regions of the deep ocean seafloor to establish standards of characterization for ecosystem-based classification. The approach was to apply semi-automated characterization techniques on seafloor bathymetric data that were originally collected for other purposes. The purpose of generating these maps is ultimately to apply to informing ecosystem-based management for large marine regions. While seafloor classification techniques for habitat classification have been applied in shallow water and generally over more local …

Quantifying The Effects Of Land Use And Flow Regime On Metabolism In New England Streams, Daniel R. Bolster

Master's Theses and Capstones

Metabolism in aquatic ecosystems influences food webs and water quality but is potentially altered by changes in land use and flow regime. The interacting effects of storms and land use on stream metabolism are largely understudied. The goal of this study was to understand how flow variability and land use interact to affect biogeochemical cycling in headwater streams. In situ measurements of stage, water temperature, and dissolved oxygen (DO) were made in three headwater streams draining different land uses (urban, forest, and mixed) and one larger river site from July 2017 to January 2018. All streams were located in the …

Effects Of Transmission Side Lobe Interference On Multibeam Echosounder Phase Ramps, Jonathan Hamel

Master's Theses and Capstones

Many multibeam echosounders use split-aperture correlators to generate phase ramps and, subsequently, form bottom detection estimates. The noise present within the phase ramp couples directly into bottom detection estimates. This results in increased bottom detection estimate uncertainty. Known sources of phase ramp noise are additive random noise and baseline decorrelation. Anecdotally, these known sources of noise do not appear sufficient to explain phase ramp noise in several(though not all, e.g. the Simrad ME70) bottom mapping multibeam echosounders. The goal of this thesis was to explore a hypothesis for where additional phase ramp noise might be generated. In pursuit of this …

Potential For Non-Conventional Use Of Split-Beam Phase Data In Bottom Detection, Leonardo Gomes De Araujo

Master's Theses and Capstones

Because the safety of the navigation depends on accurate knowledge of the submerged features, any improvements in the ability to resolve those features are of major interest. Ultimately this reflects the bottom detection performance of the bathymetric measuring system (most commonly multibeam sonar) utilized. To this end, different algorithms for the detection of the seafloor or other targets have previously been developed, all presenting advantages and disadvantages. The two most common techniques are designed around time-series or angle-series analysis, although by far the most focus has been on time-series. The option of recording both amplitude and phase data of the …

Recovering Untold Stories: Everyday Lives Of Women In Republican Istanbul, 1930-1960, Zehra Betul Atasoy

Dissertations

This research explores the everyday lives of urban women from various social strata in Istanbul between 1930 and 1960. It designates the implications of the Republican reforms in urban spaces and concentrates on untold stories of women who belonged to varying social settings and professions. The everyday life of the city became more complex with the increase in participation of women during these decades. This research examines the myriad ways in which women asserted themselves in the urban fabric, following three threads. First, women's leisure and economic activities in the newly built public squares are investigated. Then, industrial workers and …

Model Minorities: Asian Americans And The White-Black Racial Paradigm, Jason Tom

Theses and Dissertations

This paper examines the racial wedge driven by Whites between Blacks and Asian Americans during the Cold War on to the present. Model minorities is a term coined by whites in the 1960s to suppress Civil Rights protests and Black demands. By elevating a minority group through success stories, whites constructed a means to suppress Black people’s organizing for change against systemic racism and oppression.

The Relationship Between Narrative Informativeness And Psychosocial Outcomes In Chronic Stroke-Induced Aphasia, Eileen Armes, Jessica Richardson, Rick Arenas, Lori Nelson

Speech and Hearing Sciences ETDs

Currently there is a gap in the literature in understanding the relationship between the newly categorized primary outcome measure of discourse and secondary outcomes related to psychosocial impact, such as participation, psychological impact, social well-being, or mood. In a large sample of persons with stroke-induced aphasia (N=115), this study analyzed discourse samples using main concept analysis to determine how discourse performance correlates with the secondary outcome measures ALA, CCRSA, GDS, and CIQ. As a secondary research question, the differences in these relationships dependent on severity was also explored. Results showed statistically significant positive correlations between main concepts (MCs) and ALA …

Molecular Mechanism Of Cyanobacteria Circadian Clock Oscillator And Effect Of Co Factors On Its Oscillation, Manpreet Kaur

Dissertations

The circadian rhythms arise as an adaptation to the environmental 24-hour day and night cycle due to Earth's rotation. These rhythms prepare organisms to align their internal biological activities and day to day behavior or events with the environmental change of the 24-hour day and night cycle. Circadian rhythms are found widely in all living kingdoms of life on Earth. Cyanobacteria are photosynthetic prokaryotes which first used to study these circadian rhythms. Among cyanobacterial species, Synechococcus elongatus PCC 7942 (henceforth, S. Elongatus) is the simplest organism with a durable and sturdy circadian clock and is study as a model organism. …

Coordination, Adaptation, And Complexity In Decision Fusion, Weiqiang Dong

Dissertations

A parallel decentralized binary decision fusion architecture employs a bank of local detectors (LDs) that access a commonly-observed phenomenon. The system makes a binary decision about the phenomenon, accepting one of two hypotheses (H0 (“absent”) or H1 (“present”)). The k 1 LD uses a local decision rule to compress its local observations yk into a binary local decision uk; uk = 0 if the k 1 LD accepts H0 and uk = 1 if it accepts H1. The k 1 LD sends its decision uk over a noiseless dedicated channel to a Data Fusion Center (DFC). The DFC combines the …

Development Of Novel Inks And Approaches For Printing Tissues And Organs, Shen Ji

Dissertations

Tissue engineering is a multidisciplinary field that investigates and develops new methods to repair, regenerate and replace damaged tissues and organs, or to develop biomaterial platforms as in vitro models. Tissue engineering approaches require the fabrication of scaffolds using biomaterials or fabrication of living tissues using cells. As the demands of customized, implantable tissue/organs are increasing and becoming more urgent, conventional scaffold fabrication approaches are difficult to meet the requirements, especially for complex large-scale tissue fabrication. In this regard, three-dimensional (3D) printing attracted more interest over the past decades due to its unrivaled ability to fabricate highly customized tissues or …

Drone-Assisted Emergency Communications, Di Wu

Dissertations

Drone-mounted base stations (DBSs) have been proposed to extend coverage and improve communications between mobile users (MUs) and their corresponding macro base stations (MBSs). Different from the base stations on the ground, DBSs can flexibly fly over and close to MUs to establish a better vantage for communications. Thus, the pathloss between a DBS and an MU can be much smaller than that between the MU and MBS. In addition, by hovering in the air, the DBS can likely establish a Line-of-Sight link to the MBS. DBSs can be leveraged to recover communications in a large natural disaster struck area …

A Deep Machine Learning Approach For Predicting Freeway Work Zone Delay Using Big Data, Abdullah Shabarek

Dissertations

The introduction of deep learning and big data analytics may significantly elevate the performance of traffic speed prediction. Work zones become one of the most critical factors causing congestion impact, which reduces the mobility as well as traffic safety. A comprehensive literature review on existing work zone delay prediction models (i.e., parametric, simulation and non-parametric models) is conducted in this research. The research shows the limitations of each model. Moreover, most previous modeling approaches did not consider user delay for connected freeways when predicting traffic speed under work zone conditions. This research proposes Deep Artificial Neural Network (Deep ANN) and …

Human-Robot Interaction For Assistive Robotics, Jiawei Li

Dissertations

This dissertation presents an in-depth study of human-robot interaction (HRI) withapplication to assistive robotics. In various studies, dexterous in-hand manipulation is included, assistive robots for Sit-To-stand (STS) assistance along with the human intention estimation. In Chapter 1, the background and issues of HRI are explicitly discussed. In Chapter 2, the literature review introduces the recent state-of-the-art research on HRI, such as physical Human-Robot Interaction (HRI), robot STS assistance, dexterous in hand manipulation and human intention estimation. In Chapter 3, various models and control algorithms are described in detail. Chapter 4 introduces the research equipment. Chapter 5 presents innovative theories and …

Experiments And Modeling Of The Chemo-Mechanically Coupled Behavior Of Polymeric Gels, Nikola Bosnjak

Dissertations

Polymeric materials consist of mutually entangled or chemically crosslinked long njitmolecular chains which form a polymer network. Due to their molecular structure, the njitpolymeric materials are known to undergo large deformation in response to various njitenvironmental stimuli, such as temperature, chemical potential and light.

When a polymer network is exposed to a suitable chemical solvent, the solvent molecules are able to diffuse inside the network, causing it to undergo a large volumetric deformation, known as swelling. In addition to volumetric deformation, this process involves the chemical mixing of the polymer network and solvent molecules, and is typically environmentally responsive. A …

High-Speed Rail Safety Analysis Based On Dual-Weighted Complex Network, Liu Lv

Dissertations

This study uses a complex network model to analyze the causes of accidents in high-speed railway operations. By identifying the key factors that led to high-speed railway accidents, hidden safety hazards were discovered. This will help improve the operational safety of the U.S. high-speed rail line under construction.

The analysis uses the regional high-speed railway network in Guangzhou, China as a case study, including the railway (including high-speed railway) accidents that occurred in the company's jurisdiction from 2013 to 2017. With comparative analysis between general railways and high-speed railways, the changes of high-speed railway safety factors are explored. Data analysis …

Supporting User Interaction And Social Relationship Formation In A Collaborative Online Shopping Context, Yu Xu

Dissertations

The combination of online shopping and social media allow people with similar shopping interests and experiences to share, comment, and discuss about shopping from anywhere and at any time, which also leads to the emergence of online shopping communities. Today, more people turn to online platforms to share their opinions about products, solicit various opinions from their friends, family members, and other customers, and have fun through interactions with others with similar interests. This dissertation explores how collaborative online shopping presents itself as a context and platform for users' interpersonal interactions and social relationship formation through a series of studies. …

Dances And Escape Of The Vortex Quartet, Brandon Behring

Dissertations

This dissertation considers the linear stability of a one-parameter family of periodic solutions of the four-vortex problem known as 'leapfrogging' orbits. These solutions, which consist of two pairs of identical yet oppositely-signed vortices, were known to W. Gröbli (1877) and A. E. H. Love (1883) and can be parameterized by a dimensionless parameter related to the geometry of the initial configuration. Simulations by Acheson and numerical Floquet analysis by Tophøj and Aref both indicate, to many digits, that the bifurcation occurs at a value related to the inverse square of the golen ratio. Acheson observed that, after an initial period …

Online Fulfillment: F-Warehouse Order Consolidation And Bops Store Picking Problems, Wen Zhu

Dissertations

Fulfillment of online retail orders is a critical challenge for retailers since the legacy infrastructure and control methods are ill suited for online retail. The primary performance goal of online fulfillment is speed or fast fulfillment, requiring received orders to be shipped or ready for pickup within a few hours. Several novel numerical problems characterize fast fulfillment operations and this research solves two such problems. Order fulfillment warehouses (F-Warehouses) are a critical component of the physical internet behind online retail supply chains. Two key distinguishing features of an F-Warehouse are (i) Explosive Storage Policy – A unique item can be …

Characterizing Reactive Iron Mineral Coatings And Their Roles In Natural Attenuation At A Site With Historical Contamination, Han Hua

Dissertations

Reactive iron mineral coatings in redox transition zones play an important role in contaminant attenuation. These mineral coatings include poorly crystalline to crystalline iron sulfides, carbonates, and oxyhydroxides, and are a signature of the biogeochemical processes occurring. To better understand these processes, reactive iron mineral coatings are characterized in an 18-m Anaerobic Core collected from a contaminated industrial site. This study targets redox transition zones uncovered in the core. A suite of complementary analyses is applied to distinguish the surface coating mineralogy using X-ray Diffraction, X-ray fluorescence, and field-emission scanning electron microscopy (FESEM) with energy dispersive X-ray analyzer (EDX). In …

The Aging And Impacts Of Atmospheric Soot: Closing The Gap Between Experiments And Models, Ogochukwu Yvonne Enekwizu

Dissertations

The main goal of this dissertation is to generate data and parameterizations to accurately represent soot aerosols in atmospheric models. Soot from incomplete combustion of fossil fuels and biomass burning is a major air pollutant and a significant contributor to climate warming. The environmental impacts of soot are strongly dependent on the particle morphology and mixing state, which evolve continuously during atmospheric transport via a process known as aging. To make predictions of soot impacts on the environment, most atmospheric models adopt simplifications of particle structure and mixing state, which lead to substantial uncertainties. Using an experimentally constrained modeling approach, …

Performance Optimization Of Big Data Computing Workflows For Batch And Stream Data Processing In Multi-Clouds, Huiyan Cao

Dissertations

Workflow techniques have been widely used as a major computing solution in many science domains. With the rapid deployment of cloud infrastructures around the globe and the economic benefits of cloud-based computing and storage services, an increasing number of scientific workflows have migrated or are in active transition to clouds. As the scale of scientific applications continues to grow, it is now common to deploy various data- and network-intensive computing workflows such as serial computing workflows, MapReduce/Spark-based workflows, and Storm-based stream data processing workflows in multi-cloud environments, where inter-cloud data transfer oftentimes plays a significant role in both workflow performance …

The Stability Of Nanobubbles And Its Application In Contaminated Sediment Treatment, Shaini Dilsha Aluthgun Hewage

Dissertations

This dissertation consists of two sections. First, nanobubbles' stability and behavior are studied using experimental and theoretical approaches. Second, nanobubbles application combined with ultrasound to remediate contaminated sediments is discussed.

The stability study consists of four sections. (i). Laboratory investigation to determine bubble size distributions and zeta potentials for different gases, pH levels, temperatures, and salt conditions. (ii). A theoretical study based on the diffused double layer theory to explain nanobubbles' behavior in different NaCl concentrations. (iii). Nanobubbles' stability in electrolyte solutions under different ion valencies using deionized water, NaCl, Na₂SO₄, Na₃PO₄, …

Modeling Mass Transfer And Chemical Reaction In Industrial Nitrocellulose Manufacturing Processes, Francis Patrick Sullivan

Dissertations

A series of models are proposed to describe the production of military grade nitrocellulose from dense cellulose materials in mixtures of nitric acid, sulfuric acid, and water. This effort is conducted to provide a predictive capability for analyzing the rate and extent of reaction achieved under a range of reaction conditions used in the industrial nitrocellulose manufacturing process for sheeted cellulose materials. Because this capability does not presently exist, nitrocellulose producers have historically relied on a very narrow range of cellulose raw materials and resorted to trial and error methods to develop processing conditions for new materials. This tool enables …

Small-Scale Dynamics Of Photospheric Magnetic Activities And Their Chromospheric Responses, Jiasheng Wang

Dissertations

The evolution of photospheric magnetic fields is considered as the fundamental source of forming atmospheric structures and triggering most solar activities, including flares and mass ejections on various scales (CMEs, jets, etc.). With the implementation of high-resolution observational instruments, small-scale details of magnetic features are recognized that can provide important information regarding the evolution in active regions and the connection between photospheric magnetic reconnection and jet-like ejections in the quiet Sun. This research takes advantage of the exceptionally high-resolution measurements of vector magnetic field and imaging observations by the Goode Solar Telescope, and UV/EUV imaging observations from space-based instruments. The …

White Discipline, Black Rebellion: A History Of American Race Riots From Emancipation To The War On Drugs, Jordan C. Burke

Doctoral Dissertations

This dissertation is a comparative analysis of American race riots, within and across historical eras, from Emancipation (1863) to the War on Drugs (1972). I argue that changes in the status of African-American citizenship produced different forms of race rioting. Examining riot events across eras reveals how ethical principles at the core of democracy are undermined in specific socio-historical contexts—especially equality of participation in collective self-governance. Congressional testimony, state-sponsored riot investigations, and archival data indicate that riots have been used historically to structure racial inequality in both political institutions and economic relations. While race riots have proven instrumental in maintaining …

Analysis Of The Population Dynamics Of Placida Dendritica And Codium Fragile In The Gulf Of Maine And A Theoretical Discussion Of Invasive Species, Seth Goodnight

Doctoral Dissertations

This dissertation examines several aspects of the biology and ecology of Codium fragile and Placida dendritica in the Gulf of Maine. Scientific interest in nonindigenous species was examined to determine if any patterns were evident that might indicate a change in the status of an invasive species. Interest in C. fragile had waned in recent years, the timing of which coincides with the decreased ecological dominance and apparent naturalization of the alga. Laboratory and field studies were combined to quantify the dynamics in the population of C. fragile and in the recruitment dynamics of P. dendritica. Results of laboratory research …

Examining The Overlooked Complexities Of School Lunch: An Investigation Into The Juncture Of Food, Schooling, And The Developing Adolescent, Eleanor Kane

Doctoral Dissertations

School lunch is a universal experience for students everywhere and yet remains largely understudied by educational researchers. This dissertation explores school lunch through the lens of adolescent identity theory, with the purpose of investigating the unarticulated and overlooked complexities inherent in the lunch block, from issues of the developing sense of self, to social and cultural meanings surrounding food, and consequences for social reproduction. I used a combination of ethnographic observations and narrative interviews at a rural New England high school, focusing on participants’ daily habits, food practices, and choices during the lunch block. Through this, I established the normative …

Characterizing Student Engagement In A Post-Secondary Developmental Mathematics Class And Exploring The Reflexivity Between Social And Sociomathematical Norms, David Fifty

Doctoral Dissertations

Traditionally, post-secondary developmental mathematics courses aspire to equip students with mathematical content knowledge needed to succeed in calculus and subsequent STEM courses. The literature shows that this goal alone is insufficient, as the emphasis on content acquisition often comes at the expense of developing higher-order skills such as argumentation, reasoning, and flexibility in mathematics problem solving (Chiaravalloti, 2009; Partanen & Kaasila, 2014; Star et al., 2015). Redesigning curricula with these additional objectives in mind requires providing students with opportunities to engage with mathematics in ways that may contrast with their past experiences or expectations. It requires changing patterns of classroom …

Magnetoelastic Excitations In Chiral Magnets, Christopher Libby

Doctoral Dissertations

Emergence of quasiparticles is a central concept in condensed matter physics. As an example, in solids, lattice vibrations lead to quantized phonon excitations, which gives rise to many exotic phenomena, including superconductivity. Things become richer in magnetic systems. Collective fluctuations about a magnetic ground state induce the spin wave excitation, whose quantized quasiparticle is dubbed as the magnon. A fundamental question is how phonon and magnon, as two separate degrees of freedom, can be coupled together. More importantly, certain symmetry, such as spatial inversion symmetry, can be broken in novel magnetic textures. It is interesting to explore whether broken symmetry …