Digital Commons Network^™

The Association Between Obesity And Covid-19: An Analysis Of Risk Factors, Talib H. Hakim

Honors Undergraduate Theses

The purpose of this study was to focus on whether solely obesity (measured by BMI) leads to an increased risk of COVID-19 mortality in terms of excess in-hospital deaths. As the grim milestone of one million deaths in the United States from COVID-19 was reached, one could assume the disease would continue to coexist with humanity in the long term. While vaccination continued to limit the spread of COVID-19, it was essential to investigate risk factors that may exacerbate the severity of the illness in humans. Obesity is already a global pandemic affecting 40% of Americans and over 650 million …

The Impact Of Head And Neck Surgical Scars On Appearance And Acceptance Of Dermatography As A Cosmetic Intervention, Simcha Chaitoff

Honors Undergraduate Theses

Many surgical procedures in the head and neck regions produce visible scarring. The most common of these surgeries are tracheotomies and thyroidectomies. The recent COVID-19 pandemic has caused an increase in tracheotomy scars, particularly in those who survived severe infection with the disease and required long-term ventilation. Individuals with neck scars are at an increased risk of health consequences such as reduced quality of life, depression, and negative body image. Research on attitudes toward and reactions to individuals with such scarring is limited. The purpose of this study is to examine how people rate images of scarred individuals on personality …

Assessing The Feasibility, Acceptability, Appropriateness, Barriers, And Facilitators To Implementing Naloxone Distribution In Residential Areas At Ucf, Isabella S. Arguello-Howe

Honors Undergraduate Theses

With the rise of accidental fentanyl overdoses and recreational opioid use in college-aged populations, the need for campus-based overdose prevention and harm reduction measures is at an all-time high. Naloxone, an opioid antagonist, is an FDA-approved, lifesaving, medication which can be intranasally delivered by laypersons. Naloxone reverses opioid overdose, essentially buying time until an overdosing individual receives emergency medical attention. While some previous studies have examined access to naloxone on college campuses, to my knowledge no study has explored distribution of naloxone in residential college areas, such as dormitories and within Greek housing. Therefore, the purpose of this thesis was …

Effects Of Mental Health Disorders On Time Perception, Mirella S. Galliano-Rechani

Honors Undergraduate Theses

Research suggests a relationship between time distortion and mental health disorders, and the present study sought to examine this proposition. Prior research suggests that negative emotions are associated with the slowing down of time. Because mental health disorder symptomology is associated with more negative emotions, it was predicted that negative emotions would mediate the relationship between mental health disorder symptomology and time distortion. A survey was administered to university students that contained measures of anxiety, depression, emotional experiences, and time perception. Mental health disorder symptomology was found to be related to negative emotions. However, negative emotions and mental health disorder …

An Examination Of Lung Cancer Treatment Characteristics On Lung Cancer Patients With Co-Existing Heart Disease, Elias Rhanime

Honors Undergraduate Theses

With the rising rates of heart disease incidents in the United States and the increase in lung cancer deaths as well, many individuals suffer and get their treatments compromised due to these diseases. Especially considering that many lung cancer and heart disease patients are over 70 years of age, treatment options and success rates drop significantly. Due to this, a great concern is raised for patients with co-existing heart disease and lung cancer. This was a case-control study that assessed lung cancer treatment options and success rates for patients with co-existing heart disease. We used research papers that discussed lung …

Analyzing The Relationship Between The Quality Of Life And Race Of Lung Cancer Survivors, Alina S. Wise

Honors Undergraduate Theses

Purpose: The relationship between racial disparities and the health-related quality of life (HRQoL) of lung cancer patients is not well understood. The purpose of this study was to quantify the overall HRQoL of lung cancer patients and compare differences in HRQoL among racial groups in the United States.

Methods: We analyzed data from the Behavioral Risk Factors Surveillance System (BRFSS), a population-based national cross-sectional study conducted by the Centers for Disease Control and Prevention. The BRFSS is conducted annually in all 50 states and collects information on demographics, health behaviors, health-related experiences, health conditions, use of medications, and use of …

Mechanical Understanding And Optimization Of Template Guided Core Needle Biopsy, Isaac Girgis

Honors Undergraduate Theses

Prostate cancer is the second highest cause of cancer related deaths among men. According to the diagnostic pathway for prostate cancer, a prostate biopsy is performed if an individual showed signs of lesions through high prostate-specific antigen (PSA) concentration or suggestive digital rectal exam (DRE) results. The core biopsy mechanism involves inserting a beveled needle into the organ and removing a cylindrical fragment of tissue. Many factors affect the histological quality of the sample, including fragmentation, needle deflection, and needle insertion velocity. If a biopsy core is not clinically viable, an alternative core will need to be taken, resulting in …

Mental Health Attitudes And Knowledge Among Shia Muslims In America, Fatima Z. Hussain

Honors Undergraduate Theses

Mental health has received more attention and stigma associated with it has decreased over time in the United States. However, subpopulations have differing views on mental illness since cultural factors can shape perceptions of and influence access to mental health information. Previous studies have investigated such cultural factors among Sunni Muslims (the majority sect of Islam) and less so among Shia Muslims (the minority sect). To address this gap, two research questions were investigated in this project: (1) What are the mental health attitudes among Shia Muslim adults in the United States, and (2) How much mental health knowledge or …

Investigating The Relationship Between Biological Age And Mutant Huntingtin Misfolding, Ratnesh Kesineni

Honors Undergraduate Theses

Huntington Disease (HD) is an autosomal dominant neurodegenerative disease caused by an expansion of a CAG trinucleotide repeat tract in the huntingtin (HTT) gene. This CAG tract expansion causes production of mutant HTT (mtHTT) protein, which misfolds and forms inclusions in the brain that accumulate with age. Misfolded mtHTT aggregates have been linked with increased cell death in neuron cell culture, leading to speculation that mtHTT aggregates cause cell death. However, there are mouse lines that have robust mtHTT inclusion deposition, but no HD-like signs or neurodegeneration. Furthermore, neuronal HD cultured cells with inclusions were found to be …

The Effect Of Young Blood Anti-Aging Treatment On Protein Markers Of Age And Huntington Disease, Sujena H. Koilpillai

Honors Undergraduate Theses

Huntington disease (HD) is a neurodegenerative disorder caused by expansion of a polyglutamine tract within the huntingtin (HTT) protein, forming mutant HTT (mtHTT). HD patients suffer from psychiatric, behavioral, cognitive, and motor abnormalities, with death typically occurring 15-20 years after symptom onset. Currently, there are no treatments able to slow disease progression or delay onset. HD is a disease of aging. Despite the mtHTT protein being produced throughout life, symptoms do not typically appear until adulthood. Furthermore, many cellular effects of normal aging are also seen in HD, including altered intercellular communication and loss of proteostasis. Recently, our lab found …

Covid-19 And Diabetes, Radhika Desai

Honors Undergraduate Theses

Patients with Type 2 Diabetes (T2D) have been found to have increased mortality and morbidity for COVID-19 and are at higher risk for severe disease once infected with COVID-19. Clearly, there exists a relationship between T2D and COVID-19 that requires more attention. In order to understand the mechanisms by which T2D contributes to more severe COVID-19 disease, attention was turned to extracellular vesicles (EVs). It was speculated that viral RNA components of the COVID-19 virus may have originated from circulating EVs that came from infected cells and use a Trojan Exosome method to infect host cells. It is necessary to …

The Effects Of Anxiety On Vision Related Performance Among Collegiate Athletes, Aviana R. Fedele

Honors Undergraduate Theses

Anxiety is an intense feeling of worry or fear and can often be overwhelming, taking over someone’s everyday activities. Oftentimes, individuals who have feelings of anxiety or are in stressful situations that are anxiety inducing, they can get physical symptoms such as increased heart rate, sweating, fatigue and rapid breathing. Anxiety can also affect an individual’s quality of vision. In circumstances that are highly stressful, individual’s vision can start to diminish temporarily, affecting the peripheral vision as well as making central vision blurry. This study examines the effects of anxiety and vision quality on athletic performance among collegiate athletes. It …

Diabetes Mellitus Among Black/African Americans: A Critical Discourse Analysis Of Epigenetic Research, Eliana Jacobs

Honors Undergraduate Theses

During their lifetime, Black/African Americans have a higher likelihood of developing the diabetes mellitus metabolic disorder than other racial and ethnic groups in the United States. While research indicates that socioeconomic status, diet, and obesity factor into race disparities, the epigenetics field additionally identifies historical and contemporary racism as contributors to race disparities. This study is a qualitative analysis that examines a sample of health science research articles that use an epigenetics approach to understand diabetes among Black/African Americans. I analyzed the extent and mechanisms through which articles subtly reproduce dominant stereotypes of Black/African Americans and diabetes through representations of …

The Lived Experience Of Simulation In Nursing Education Related To Postpartum Depression And Healthcare Disparities, Erin Tonkin

Honors Undergraduate Theses

Background: Postpartum mothers are often initially screened for postpartum depression (PPD) but lack adequate follow up visits after discharge from the hospital post-delivery, despite the variety of complications that can arise from it. Additionally, healthcare disparities (HCD) have been shown to limit access to and the quality of healthcare for minority patients. Simulation-based education offers learners an opportunity to practice screening for PPD with the goal of improving the quality of care for these patient subgroups in future practice. Purpose: The purpose of this study was to explore the lived experience of SBE with prelicensure student nurses in an effort …

The Relationship Between Sarcopenia And Diabetes Among Different Ethnic Groups, Rachel K. Williams

Honors Undergraduate Theses

Sarcopenia and diabetes are two conditions that reflect ongoing changes in global health trends: aging and obesity. Sarcopenia affects approximately 10-40% of the global population and type II diabetes affects around 415 million individuals (6.28% globally), with obesity contributing to a majority of the cases. Currently, approximately 9.3% of the population (727 million individuals) is aged 65 years or older; this number is predicted to reach 16% of the global population (around 1.5 billion individuals) in 2050. Many developed countries are undergoing demographic population pyramid rearrangements whereby an increasingly aging population must be supported by a shrinking youth cohort. Sarcopenia …

The Impact Of Sickle Cell Disease On Gingival Bleeding And Oral Health Of Adults, Natalie Roa

Honors Undergraduate Theses

Oral health may serve as an indicator of overall systemic health, with each disease or condition manifesting differently in the oral cavity. Sickle cell disease (SCD) is a genetic disorder in which sickled red blood cells cause blood vessel occlusion and potentially bleeding in specific sites (e.g., gastrointestinal and intracranial bleeding). With SCD being one of the most common hereditary diseases in the world, it is essential to understand the disease and improve awareness to better treat this population. While studies have been done to evaluate the oral health of persons with SCD, few have explored the occurrence of gingival …

The Impact Of Endometriosis-Associated Pelvic Pain On The Social And Academic Wellbeing Of Women Enrolled In University, Ava E. Bettencourt

Honors Undergraduate Theses

Background: Endometriosis, a medical condition in which endometrial tissue lining grows outside of the uterus, affects approximately 10-15 percent of women of reproductive age. While research has shown that symptoms of endometriosis negatively affect quality of life in women, few studies have examined the impact of this condition specifically in college students who may be overwhelmed with the stress of school, living independently, and managing the symptoms of their endometriosis. Purpose: To examine the impact of endometriosis on academic and psychosocial factors in university students. Methods: Four college females completed the Pain Self-Efficacy Questionnaire (PSEQ), a 10-item survey used to …

Stress, Coping, And Disease Awareness With Metabolic Disease Risk: A Longitudinal Cohort Study, Chelsea Anestal

Honors Undergraduate Theses

College students undergo stressors (e.g., potential financial strain, changes in workload or location), which may precipitate metabolic syndrome (MetS) risk associated with obesity and high blood pressure. Concerning rises in young adult obesity and type 2 diabetes, prompt study into MetS risk factor prevalence and awareness in youthful populations transitioning to new environments, such as college. This study assessed perceived stress, coping resources, and disease awareness differences in the first time on campus and final-year students associated with MetS risk factors (elevated body mass index (BMI) and blood pressure). We hypothesized lower stress perception, lower weight gain and blood …

Characteristics Of Covid-19 Vaccine-Hesitant Ucf College Students And Potential Avenues For Increasing Vaccination Rates, Justin A. Barthel

Honors Undergraduate Theses

The COVID-19 pandemic has been an ongoing disaster that has devasted millions of lives. With the development of COVID-19 vaccines in late 2020, there was a potential for populations to gain artificial active immunity in order to prevent future outbreaks. However, despite successful clinical trials, millions of citizens have been hesitant to receive the COVID-19 vaccines (Khubchandani et al., 2021). Demographics of the most prominent US vaccine-hesitant populations consist of ethnic/racial minorities and Republicans groups (Khubchandani et al., 2021). Little information is known about COVID-19 vaccine hesitancy in colleges and universities. Colleges provide an elevated risk for infection through their …

Cancer Survivors' Physical Activity Advice: A Guide For Assessment And Implementation For Nurses And Healthcare Workers, Kayla Burd

Honors Undergraduate Theses

Background: Physical activity (PA) improves cancer-related symptoms (e.g., fatigue, sleep) in cancer survivors, although there is low adherence due to barriers. Cancer survivors are interested in participating in PA but healthcare providers feel they have inadequate knowledge in PA and lack guidance to provide PA support.

Purpose: Examine PA advice for cancer survivors and healthcare providers from cancer survivor interviews to understand cancer survivors’ PA and create an algorithm to help healthcare providers assess and provide PA advice to cancer survivors.

Method: Qualitative content analysis of twenty interviews with cancer survivors regarding PA.

Results: Cancer survivors advised health care providers …

Evaluating Non-Pharmaceutical Sleep Hygiene Interventions For The Prevention Of Delirium And Improvement In Sleep Quality In Critical Care, Sonja L. Colby

Honors Undergraduate Theses

Patients admitted to an adult intensive care unit (ICU) are at risk of developing an acute condition known as ICU delirium, which can impact patients’ length of hospital stay and increase short term and 6-month mortality. The cause of ICU delirium is multifactorial, and lack of quality sleep is a known risk factor. Patients’ sleep in the ICU is frequently interrupted by clinicians involved in their care and equipment alarms. Sleep hygiene interventions to minimize these interruptions for the patient are one strategy to reduce the risk of ICU delirium. Examples of sleep hygiene interventions include eye masks, earplugs, and …

Examining The Use Of Digital Tools To Facilitate Multilingual Patient-Physician Communication: A Scoping Review, Esha V. Ghosalkar

Honors Undergraduate Theses

The United States healthcare system cares for and supports a diverse patient population. Patients come from various ethnic backgrounds, speak different languages, hold distinct religious affiliations, and more. These differences can create a chasm in the patient-provider relationship, impacting the quality of care or health outcomes. Specifically, language-discordance can affect patient-provider communication; however, technological interventions, such as access to electronic medical record tools and digital translators, can facilitate this dyadic communication. This scoping review examines the literature present on the use of digital tools to facilitate multilingual patient-provider communication. The initial search in PubMed with MeSH terms resulted in 531 …

Evaluation Of Interactions Of Covid Nonstructural Proteins 3, 5, And 6 With Human Proteins And Potentially Therapeutic Molecules, Jessica Huitsing

Honors Undergraduate Theses

The COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2, or SARS-CoV-2, has been ongoing for over two years. The virus spreads easily and is more unpredictable than well-known viruses like the flu, making it important to have reliable combative measures before we fully drop non-vaccine preventive actions, like mask-wearing.Therefore, we used computational protein modeling to investigate the interactions of three nonstructural proteins (abbreviated Nsp) encoded in the viral RNA genome– Nsp3, Nsp5, and Nsp6 – which are involved in the viral life cycle, with human P-type polyamine transporting ATPases ATP13A2 and ATP13A3, whose disease symptoms when mutated mimic …

The Affects Of The Foot Conditions On The Homeless Population, Alexander Kaye

Honors Undergraduate Theses

The research is attempting to acknowledge and explain the impact, if any, on homeless individuals not wearing socks. The curiosity for this study started on December 25th, 2018 when my family and I were volunteering at a homeless shelter in South Florida. After having numerous conversations with homeless individuals, I was informed on how they do not have enough pairs of socks to keep their feet in a healthy condition. Thus, I decided to initiate a sock drive to improve the lives of those who are homeless. This study is looking at a series of articles that are reviewing the …

Regulation Of The Protease Activity For The Mitochondrial Omi/Htra2, Simon Larson

Honors Undergraduate Theses

Human High Temperature requirement A2 (HtrA2) also known as Omi, is a serine protease located in the mitochondria with an important function in both cell survival and death. My results show the proteolytic activity of Omi/HtrA2 varies under different conditions. I characterized the optimal condition for Omi/HtrA2 protease activity using an in vitro assay system. Additionally, I identified a new allosteric regulation of Omi/HtrA2 through interaction with a specific substrate, the MUL1 protein. MUL1 is a multifunctional E3 ubiquitin ligase anchored in the outer mitochondrial membrane with domains both inside mitochondria and in the cytoplasm. The data shown here strongly …

An Introduction To The Comparison Of Seismocardiography And Phonocardiography, Anna C. Voyatzoglou

Honors Undergraduate Theses

The intent of this thesis is to lay groundwork for examining the relationship between seismocardiography (SCG) and phonocardiography (PCG). Both are methods of measuring and describing heart mechanical function. SCG is described as chest vibrations while the heart beats, and PCG is described as acoustic chest surface signal believed to represent the heart valves opening or closing. SCG and PCG have both been used separately in clinical and research settings, but there is currently no clear comparison between the two. Therefore, there has been no way at the present to understand how one signal might inform the other. This study …

Exploring Genz’S Attitudes About Mental Illness: Are They More Accepting?, Katelyn E. Yarbrough

Honors Undergraduate Theses

It is assumed that stigmas surrounding mental illnesses have begun to lessen over time. Generation Z seems to be the most accepting of neurodivergent individuals and people with mental illnesses (Bethune, 2019). However, existing literature suggests that college students continue to have negative attitudes toward mental illnesses, which could lead to a refusal of mental health services, unsafe social environments, and self-medication (Phelan & Basow, 2007). To further investigate GenZ’s stigmas toward mental illness, this study assesses college students’ attitudes toward various mental health diagnoses including Depression, Anxiety, Attention Deficit-Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), and Eating Disorders. Specifically, …

A Mixed Methods Study On Levels Of Physical Activity And Degree Of Fear Of Falling In Older Adults, Oscar L. Garcia

Honors Undergraduate Theses

Maintaining a physically active lifestyle has shown to decrease the risks of falling by slowing down the degenerative changes that occur with aging adults. But despite these physical changes, research has recognized the development of the fear of falling (FOF) as also attributing to the aging adults’ risk of falling. Furthermore, increases the risk of falling and subsequently increases the loss of independency. This study aimed to: 1) examine the relationships between the levels of physical activity, degree of FOF, and fall risk using quantitative approach; and 2) explore the changes of FOF and understand its cause using qualitative approach. …

Differences In Nutrition And Eating Patterns Between Youth With Autism Spectrum Disorder And Neurotypical Youth, Mariam Spieler Tahech

Honors Undergraduate Theses

Background: Autism Spectrum Disorder (ASD) is a developmental disorder characterized by difficulties with communication, problems with social interactions, and repetitive patterns. A greater proportion of children with ASD tend to experience nutritional difficulties and feeding issues compared to neurotypical (NT) children; however, limited research has been examined that compares nutritional behaviors between children with ASD and NT youth. Purpose: The purpose of this study was to examine the differences in gastrointestinal issues, weight concerns, and mealtime behaviors in youth with ASD and NT youth. Data was utilized from the 2019 National Survey of Children’s Health which consisted of items related …

A Fall From Grace: The Rising Rate Of Attorneys With Substance Abuse Disorders, Chemical Dependencies And Addictions, Amy M. Yost

Honors Undergraduate Theses

This thesis is a continuation of research and scholarly writing that the author completed for a published article that appeared in Volume 5 of the University of Central Florida Undergraduate Law Journal, Spring 2022. The rising rate of attorneys with a self-reported substance abuse disorder, chemical or alcohol dependency, as the data reveals, is the highest in our country’s history. Although the notion of attorney addictions and dependency issues may come as a surprise to those outside of the legal community, these issues are not breaking news. Rather, the data has been slowly emerging due to the increasing number of …