Digital Commons Network^™

Effects Of Exercise On The Cardiovascular Health Of Adolescents And Young Adults With Down Syndrome, Samarth Gupta

Rowan-Virtua Research Day

Introduction: It is known that the incidence of Down Syndrome has increased over time and that this condition is associated with congenital heart defects, lower cardiorespiratory capacity, and increased rates of obesity and type 2 diabetes. It has been shown that individuals who have congenital heart defects but not Down Syndrome have increased cardiorespiratory function after engaging in exercise. Unfortunately, the role of exercise in improving cardiovascular health outcomes among individuals with DS is not yet fully understood.

Results: Exercise has been found to improve several health outcomes among individuals with Down Syndrome. For example, moderate to vigorous treadmill exercises …

Unraveling The Gender Disparity: Investigating The Factors Behind Women’S Higher Acl Injury Risk, Kylie Smith

Research Days

No abstract provided.

Evaluation Of Botanical Extracts For Cytochrome P450 Inhibition Mediated Drug Interactions, Angela I. Calderón, Zarna Raichura, Kabre Heck, Jaewoo Choi, Mikah Brandes, Cody Neff, Claudia Maier, Amala Soumyanath, Robert Arnold

Oxford ICSB

There has been remarkable growth in consumption of botanical dietary supplements (BDS), making it important to understand the safety profile of BDS with respect to the pharmacokinetic properties for any potential of botanical-drug interactions. One such botanical interactions which has gained significant attention involves inhibition of cytochrome P450 (CYP450) enzymes by co-administered drugs. Our study involved examining two widely used botanicals, ashwagandha and açaí for any potential inhibition of CYP450. Four different ashwagandha extracts were tested, resulting in inhibition of CYP2B6 with IC50 < 100 µg/ml of extract and showed potential of time-dependent inhibition for CYP2C9 and CYP2D6 with an IC50 ~ 200 µg/ml of extract. In the case of açaí, seven different extracts were tested and only CYP2C9 was inhibited. The acidic methanol extract of açaí formulation showed an IC50 of 0.3 µg/ml of extract indicating potent inhibition of CYP2C9, while the methanol (IC50 ~ 91.75 µg/ml) & ethanol extracts of Mountain Rose açaí powder showed weak inhibitory effect with an IC50 < 100 µg/ml of extract for CYP2C9. The results reflect that both botanical extracts showed potential of CYP450 inhibition, suggesting that compounds in BDS can prolong the half-lives of medications leading to extended action or toxicity. Next step involves, testing subfractions of these extracts to identify the compounds responsible for the observed inhibition.

Chemistry, Biology, And Safety Of Volatile Organics From Aromatic And Medicinal Plants, Nicole Stevens

Oxford ICSB

Introduction Sleep is an important foundation of health, yet the U.S. Centers for Disease Control (CDC) notes that about 30% of adults to not get the recommended minimum of 7 hours’ sleep per night. Prescription treatments may help, but they carry risks such as side-effects, dependency, and medication interaction. Natural botanical extracts are a therapeutic possibility for improving sleep quality, but additional research is needed on their efficacy and safety. A system of natural products based on lavender was developed and tested in a human clinical study to evaluate effect on sleep, blood and safety markers, and gene expression modulation …

Development And Evaluation Of Trauma Informed Care Education For Licensed Nurses, Kristina O'Meara

Epsilon Sigma at-Large Research Conference

Trauma informed care nursing education is crucial. Trauma informed care is a method of providing health care which understands the likelihood of past and present traumatic events in patients and families. The experience of past or present trauma often led to chronic diseases, substance abuse disorder, fragmented health care, fears surrounding health care, chronic stress, and other negative health consequences. The purpose of this project is to increase licensed nurses’ awareness and ability to practice trauma informed care in clinical practice, as well as promote policy initiation within the health care facilities. Method planning integrated the Knowledge to Action Cycle. …

Implementation Of Provider-Made Follow-Up Appointments For Depression In Primary Care, Rebecca Vaughn

Epsilon Sigma at-Large Research Conference

Implementation of provider-made follow-up appointments for depression in primary care

Rebecca Vaughn

College of Nursing, East Tennessee State University; Whitson Hester School of Nursing, Tennessee Technological University

Author Note

Rebecca Vaughn https://orcid.org/0009-0007-0731-3316 College of Nursing, East Tennessee State University

There are no conflicts of interest to disclose.

Corresponding concerning this manuscript should be addressed to Rebecca Vaughn

108 Reed Mill Lane Monroe TN 38573

Zrev2@etsu.edu

Abstract

Depression is a common condition diagnosed and managed in primary care.

Follow-up is inconsistent and low in these settings, creating a gap in care that

impacts management, adherence to treatment, and patient outcomes. The …

Comparisons Of Spiritual Well-Being, Psychological Well-Being, And Suicidal Ideation Between Usa And Taiwanese College Students, Pi-Ming Yeh Associate Professor, Cheng-Huei Chiao Professor, Jennchang Liou Professor

Epsilon Sigma at-Large Research Conference

Background: In Taiwan, there were 7,038 reports of attempted suicide among people aged 24 or younger in 2018. Anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the United States age 18 and older.

Purpose: In this study, we compared United States (US) and Taiwanese college students’ spiritual well-being, psychological well-being, and suicidal ideation.

Methods: A total of 661 college students (481 from the US and 180 from Taiwan) were recruited to complete the survey study. This was a cross-sectional comparative research design. SPSS 28.0 was used to do the data analysis. Chi-square …

Lingering Effects Of Covid-19 On Mental Health In College Students, Morgan Bodker

Scholars Week

This study examined whether severity of an individual’s COVID symptoms is predictive of a long-term risk for depression in college students. An online survey was completed by 123 students (M = 19.45; SD = 4.23) who had been diagnosed with COVID-19 at any time since the pandemic. Severity of COVID symptoms at the time of diagnosis was assessed using seven questions on a 4-point Likert scale. Current depressive symptoms were measured using the Patient Health Questionnaire (PHQ-9). Participants who had a COVID diagnosis reported significantly higher levels of depression than participants who have never had COVID. A linear regression restricted …

Characterizing Cold Water Drownings In The Great Lakes, Elizabeth T. Helfrich, Anthony Lagina

Medical Student Research Symposium

Since the COVID-19 outbreak in 2020, Great Lakes drownings have increased. The Great Lakes are a unique and understudied environment due to being cold, fresh water, and resuscitation protocols and guidelines being derived from warm, primarily salt water environments. We analyzed open sources materials to find records of Great Lakes drownings from 2021-2023 and analyze the data looking for trends in cold and warm water drownings.

We found 80.0-85.0% of the included drowning victims were male and had an average age of 38.0-39.0 years old. 40.0%-57.7% of Great Lakes drowning deaths were in cold water; of those, Lake Michigan had …

A Systematic Review Of The Social Determinants Of Health In Shoulder Arthroplasty Outcomes, Allison Boland, John Pum, Michael Gaudiani, Matthew A. Gasparro

Medical Student Research Symposium

This systematic review investigates the impact of social determinants of health (SDOH) on outcomes in shoulder arthroplasty (SA). SA, a common orthopedic procedure, has seen an increasing focus on SDOH influencing postoperative results. The study aims to comprehensively assess this impact on both surgical and patient-reported outcomes.

Through a systematic search of databases, 34 studies (2011-2021) met the inclusion criteria, involving 4,825,547 patients. Explored SDOH included insurance status, race/ethnicity, age, sex, income, social support, and veteran status. Outcomes considered were length of stay, American Shoulder and Elbow Surgeons scores, total SA rates, revision rates, complication rates, and discharge status.

Findings …

Conflict With Patient: Patient Will Only See Specific Gender, Dhiraj Tadikamalla, Lara Rostomian, Meet Patel, Neil Garg, Sara Naessig, Sohini Pandit, Mariam Raheem

Patient Education Projects

No abstract provided.

Conflict With Patient: Bias And Patient Care, James Burtka, Alyssa Rogers, Kaitlin Verkuilen, Maria Tjilos, Nelson Pinto, Siddharth Tirumala, Amanah Fatima, Fadi Kathawa

Patient Education Projects

No abstract provided.

Group Reflection: Self-Reflection And Identity Formation, Noor Sulaiman, Emma Breukink, Hussein Bazzi, Ranganath Kathawate, Ron Lukose, Vikram Rajan, Sahalia Rashid, Rahul Vyas

Patient Education Projects

No abstract provided.

Group Reflection: Gender Divide Of The White Coat, Alexander Minos, Carline Dugue, Ethan Mathew, Katherine Sommers, Lauren Fleckenstein, Peter Zakaria, Sahalia Rashid, Rahul Vyas

Patient Education Projects

No abstract provided.

Group Reflection: The Message Of The White Coat, Cyra Kharas, Mihika Sridhar, Paul Villa, Robert Leone, Sophia Gandarillas, Kenan Abou Chaer, Astha Saini

Patient Education Projects

No abstract provided.

Data Quality Checks: Implementation With Popular Data Collection Crowdsourcing Platforms, James Down, Gregory Balkcom, Kristine Duncan, Ngan (An) Truong, Andrew Lewis

Symposium of Student Scholars

The utilization of online crowdsourcing platforms for data collection has increased over the past two decades in the field of public health due to the ease of use, the cost-saving benefits, the speed of the data collection process, and the accessibility of a potentially true representative population. Although these platforms offer many advantages to researchers, significant drawbacks exist, such as poor data quality, that threaten the reliability and validity of the study. Previous studies have examined data quality concerns, but differences in results arise due to variations in study designs, disciplinary contexts, and the platforms being investigated. Therefore, this study …

Implicit Bias Mask 2023: Promote Openness And Inclusiveness To Address Biases, Aneesh Sai Cherukuri, Ashlee V. Perry, Ethan Dewayne Dunn, Grace Victoria Chen, Philip O. Riendeau, Sarah Jabeen Qureshi

Patient Education Projects

No abstract provided.

Implicit Bias Mask 2023: Continuously Stay Sensitive To Internalized Biases, Celia Jane Somers, Hiba S. Hasan, Jenna N. Hart, Kostantinos L. Halkias, Louis Marwan Haddad, Nikhil Paruchuri

Patient Education Projects

No abstract provided.

Implicit Bias Mask 2023: What The Eyes Do See: Learning To Grow And Respond, Aminah Juma Bharadia, Beverly Fu, Emma Ho Harris, Gabriel Khazal Boudagh, Michael David Mello, Sriraj Atluri

Patient Education Projects

No abstract provided.

Implicit Bias Mask 2023: Identify Implicit Biases To Overcome Them, Abeer Wael Abukamil, Joseph Fuad Hanania, Michael Abraham Nunu, Samar Ghassan Chehab, Vipul Taxak, Yeonju Kim

Patient Education Projects

No abstract provided.

Implicit Bias Mask 2023: Assumptions And Challenges Influence Biases, Dhwani S. Krishnan, David Elyas, Joseph D. Overway, Melissa S. Connop, Swathi Srikantan, Zahira Nawal Malik

Patient Education Projects

No abstract provided.

Implicit Bias Mask 2023: Societal Factors Define Implicit Biases, Charles Michael Hughes, Danishi Kaur Bedi, Erika P. Lopez, Jeffrey Lu, Kairo Rosario Noronha, Layla A. Darwiche

Patient Education Projects

No abstract provided.

Implicit Bias Mask 2023: Fears Of The Unknown Impacts Growth Mindset, Ananya L. Yanamandra, Christopher F. Ross, Danny Dean Salka, Hamza Khan, Julie Marie Waineo, Karen Elizabeth Zapien-Guerra

Patient Education Projects

No abstract provided.

Effects Of A Novel Botanical Supplement On Glycemic Variability And Postprandial Glucose Response, Nicole Stevens

Oxford ICSB

Mulberry leaf extract high in the iminosugar 1-deoxynojirimycin (DNJ) has been shown in previous studies to inhibit glycosidase enzyme activity. A novel supplement including mulberry leaf extract, berberine and cinnamon extract was evaluated in a two-cohort study using endpoints of glycemic variability, postprandial glucose response, fasting glucose, fasting insulin, and safety markers. In the first cohort (n=15), these endpoints were determined over two weeks by continuous glucose monitoring (CGM) and blood/urine analyses in healthy adults. Approximately half of the participants (n=7) took a dosage of 250 mg prior to each meal, and the other participants (n=8) took 500 mg before …

Nutrition Knowledge Of Young Adults: How Has K-12 Education Affected The Health Of Young Adults In 2023, Anna Polo

Scholars Day Conference

Background: Nutrition knowledge is very important in order to live a healthy lifestyle and to positively impact overall health. There is research studying the effects of nutrition education and that affects students involved in K-12 schooling, but there is a lack of research following those students beyond the classroom and to their young adult years.

Objective: The researcher’s goal was to better understand how much young adults know about basic nutrition from previous education, if different types of schooling (public, private, homeschool, etc.) taught nutrition related classes/lessons, and if different geographical regions provided nutrition education.

Design: the design was a …

University Students' Understanding Of The Endocannabinoid System And Its Relevance To Nutrition, Brittney Burford, Allyson Melton, Robbie Otero

Scholars Day Conference

The Endocannabinoid System (ECS) is a complex cell-signaling system that was identified in 1988, the ECS is the largest receptor system and regulator of homeostasis. Endogenous cannabinoids, or endocannabinoids, are naturally occurring, lipid-based neurotransmitters. Neurotransmitters are chemical messengers in the body that send signals between nerve cells. The ECS system regulates and controls many of our most critical bodily functions such as learning, memory, emotional processing, sleep, temperature control, inflammatory immune responses, and appetite. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most known phytocannabinoids. Phytocannabinoids are plant byproducts that closely mimic cannabinoids and have adverse effects on the body. Endogenous …

The Demographic Shift Of Males And Females In Veterinary Medicine, Dalton Tatum, Eddy Patterson, Mia C. Ratliff

ATU Research Symposium

The workforce in veterinary medicine saw a gender shift from a male dominated field towards women in the present day. This research aimed to determine why this shift occurred through demographic analysis and surveys to different job types in this career path. By using this data, the group determined that one of the biggest impacts of the shift is due to the very component that makes veterinary medicine such a tough field, and it is located at the graduate school entry level . The competitiveness level is intertwined through all of the data and leads to the conclusion that females …

Investigating Differences In Iga Antibody Response Against Aspergillus Fumigatus In Wild Type And Tlr7 Protein Deficient Mice, Courtney Folk

Student Academic Conference

Aspergillus fumigatus is a commonly inhaled, respiratory fungal pathogen and an allergen found in flooded indoor environments, household dust, soil, and plant matter. While a competent immune system effectively clears the inhaled fungus, this same fungus poses a significant threat to weakened immune systems due to its potential to invade the lungs, bloodstream and brain tissue. The mouse genome is 99% similar to the human genome and can serve effectively model the effects of inhaled A. fumigatus (Guénet, 2005). Antibodies play a crucial role in neutralizing pathogens and in mediating an allergic response. In this study, we will investigate the …

The Effect Of Masks On Allergic Rhinitis Symptoms Related To Ragweed And Its Influence On College Students, Katherine Knutte

Scholar Week 2016 - present

BACKGROUND: This study explored the effect of masks on allergic rhinitis related to ragweed. Research has been shown that surgical and KN95 masks reduce allergic symptoms due to dust, pollen, and ragweed. A study in Israel found a strong correlation was between wearing a KN95 and reducing severe allergic rhinitis symptoms related to nasal symptoms and another study focusing on pollen supported this finding. Lastly, a previous study on ragweed found that all nasal symptoms improved, and ocular symptoms remained unchanged.

METHODS: This was a qualitative study involving twenty college students aged 18 to 25 from Olivet Nazarene …

Animal-Assisted Green Care Farming For Patients With Traumatic Brain Injury, Alex Sargsyan

Epsilon Sigma at-Large Research Conference

Animal-Assisted Green Care Farming for Patients with Traumatic Brain Injury

Purpose

To examine the effects of Animal Assisted Therapies with Farm Animals (AATF) with domesticated ducks on depression and anxiety.

Aim

The proposed study will use single-group time series design and collect survey data to explore the changes in anxiety and depression in patients exposed to AATF. The study will be guided by the Self-Efficacy Theory. The study will involve 30 patients with TBI living in The Crumley House Rehabilitation Center in Limestone, TN.

Hypothesis. Engaging in AATF with domesticated ducks will be associated with decrease in anxiety and depression. …