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Effects Of Exercise On The Cardiovascular Health Of Adolescents And Young Adults With Down Syndrome, Samarth Gupta May 2024

Effects Of Exercise On The Cardiovascular Health Of Adolescents And Young Adults With Down Syndrome, Samarth Gupta

Rowan-Virtua Research Day

Introduction: It is known that the incidence of Down Syndrome has increased over time and that this condition is associated with congenital heart defects, lower cardiorespiratory capacity, and increased rates of obesity and type 2 diabetes. It has been shown that individuals who have congenital heart defects but not Down Syndrome have increased cardiorespiratory function after engaging in exercise. Unfortunately, the role of exercise in improving cardiovascular health outcomes among individuals with DS is not yet fully understood.

Results: Exercise has been found to improve several health outcomes among individuals with Down Syndrome. For example, moderate to vigorous treadmill exercises …


Unraveling The Gender Disparity: Investigating The Factors Behind Women’S Higher Acl Injury Risk, Kylie Smith Apr 2024

Unraveling The Gender Disparity: Investigating The Factors Behind Women’S Higher Acl Injury Risk, Kylie Smith

Research Days

No abstract provided.


Evaluation Of Botanical Extracts For Cytochrome P450 Inhibition Mediated Drug Interactions, Angela I. Calderón, Zarna Raichura, Kabre Heck, Jaewoo Choi, Mikah Brandes, Cody Neff, Claudia Maier, Amala Soumyanath, Robert Arnold Apr 2024

Evaluation Of Botanical Extracts For Cytochrome P450 Inhibition Mediated Drug Interactions, Angela I. Calderón, Zarna Raichura, Kabre Heck, Jaewoo Choi, Mikah Brandes, Cody Neff, Claudia Maier, Amala Soumyanath, Robert Arnold

Oxford ICSB

There has been remarkable growth in consumption of botanical dietary supplements (BDS), making it important to understand the safety profile of BDS with respect to the pharmacokinetic properties for any potential of botanical-drug interactions. One such botanical interactions which has gained significant attention involves inhibition of cytochrome P450 (CYP450) enzymes by co-administered drugs. Our study involved examining two widely used botanicals, ashwagandha and açaí for any potential inhibition of CYP450. Four different ashwagandha extracts were tested, resulting in inhibition of CYP2B6 with IC50 < 100 µg/ml of extract and showed potential of time-dependent inhibition for CYP2C9 and CYP2D6 with an IC50 ~ 200 µg/ml of extract. In the case of açaí, seven different extracts were tested and only CYP2C9 was inhibited. The acidic methanol extract of açaí formulation showed an IC50 of 0.3 µg/ml of extract indicating potent inhibition of CYP2C9, while the methanol (IC50 ~ 91.75 µg/ml) & ethanol extracts of Mountain Rose açaí powder showed weak inhibitory effect with an IC50 < 100 µg/ml of extract for CYP2C9. The results reflect that both botanical extracts showed potential of CYP450 inhibition, suggesting that compounds in BDS can prolong the half-lives of medications leading to extended action or toxicity. Next step involves, testing subfractions of these extracts to identify the compounds responsible for the observed inhibition.


Chemistry, Biology, And Safety Of Volatile Organics From Aromatic And Medicinal Plants, Nicole Stevens Apr 2024

Chemistry, Biology, And Safety Of Volatile Organics From Aromatic And Medicinal Plants, Nicole Stevens

Oxford ICSB

Introduction Sleep is an important foundation of health, yet the U.S. Centers for Disease Control (CDC) notes that about 30% of adults to not get the recommended minimum of 7 hours’ sleep per night. Prescription treatments may help, but they carry risks such as side-effects, dependency, and medication interaction. Natural botanical extracts are a therapeutic possibility for improving sleep quality, but additional research is needed on their efficacy and safety. A system of natural products based on lavender was developed and tested in a human clinical study to evaluate effect on sleep, blood and safety markers, and gene expression modulation …


Development And Evaluation Of Trauma Informed Care Education For Licensed Nurses, Kristina O'Meara Apr 2024

Development And Evaluation Of Trauma Informed Care Education For Licensed Nurses, Kristina O'Meara

Epsilon Sigma at-Large Research Conference

Trauma informed care nursing education is crucial. Trauma informed care is a method of providing health care which understands the likelihood of past and present traumatic events in patients and families. The experience of past or present trauma often led to chronic diseases, substance abuse disorder, fragmented health care, fears surrounding health care, chronic stress, and other negative health consequences. The purpose of this project is to increase licensed nurses’ awareness and ability to practice trauma informed care in clinical practice, as well as promote policy initiation within the health care facilities. Method planning integrated the Knowledge to Action Cycle. …


Implementation Of Provider-Made Follow-Up Appointments For Depression In Primary Care, Rebecca Vaughn Apr 2024

Implementation Of Provider-Made Follow-Up Appointments For Depression In Primary Care, Rebecca Vaughn

Epsilon Sigma at-Large Research Conference

Implementation of provider-made follow-up appointments for depression in primary care

Rebecca Vaughn

College of Nursing, East Tennessee State University; Whitson Hester School of Nursing, Tennessee Technological University

Author Note

Rebecca Vaughn https://orcid.org/0009-0007-0731-3316 College of Nursing, East Tennessee State University

There are no conflicts of interest to disclose.

Corresponding concerning this manuscript should be addressed to Rebecca Vaughn

108 Reed Mill Lane Monroe TN 38573

Zrev2@etsu.edu

Abstract

Depression is a common condition diagnosed and managed in primary care.

Follow-up is inconsistent and low in these settings, creating a gap in care that

impacts management, adherence to treatment, and patient outcomes. The …


Comparisons Of Spiritual Well-Being, Psychological Well-Being, And Suicidal Ideation Between Usa And Taiwanese College Students, Pi-Ming Yeh Associate Professor, Cheng-Huei Chiao Professor, Jennchang Liou Professor Apr 2024

Comparisons Of Spiritual Well-Being, Psychological Well-Being, And Suicidal Ideation Between Usa And Taiwanese College Students, Pi-Ming Yeh Associate Professor, Cheng-Huei Chiao Professor, Jennchang Liou Professor

Epsilon Sigma at-Large Research Conference

Background: In Taiwan, there were 7,038 reports of attempted suicide among people aged 24 or younger in 2018. Anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the United States age 18 and older.

Purpose: In this study, we compared United States (US) and Taiwanese college students’ spiritual well-being, psychological well-being, and suicidal ideation.

Methods: A total of 661 college students (481 from the US and 180 from Taiwan) were recruited to complete the survey study. This was a cross-sectional comparative research design. SPSS 28.0 was used to do the data analysis. Chi-square …


Lingering Effects Of Covid-19 On Mental Health In College Students, Morgan Bodker Apr 2024

Lingering Effects Of Covid-19 On Mental Health In College Students, Morgan Bodker

Scholars Week

This study examined whether severity of an individual’s COVID symptoms is predictive of a long-term risk for depression in college students. An online survey was completed by 123 students (M = 19.45; SD = 4.23) who had been diagnosed with COVID-19 at any time since the pandemic. Severity of COVID symptoms at the time of diagnosis was assessed using seven questions on a 4-point Likert scale. Current depressive symptoms were measured using the Patient Health Questionnaire (PHQ-9). Participants who had a COVID diagnosis reported significantly higher levels of depression than participants who have never had COVID. A linear regression restricted …


Data Quality Checks: Implementation With Popular Data Collection Crowdsourcing Platforms, James Down, Gregory Balkcom, Kristine Duncan, Ngan (An) Truong, Andrew Lewis Nov 2023

Data Quality Checks: Implementation With Popular Data Collection Crowdsourcing Platforms, James Down, Gregory Balkcom, Kristine Duncan, Ngan (An) Truong, Andrew Lewis

Symposium of Student Scholars

The utilization of online crowdsourcing platforms for data collection has increased over the past two decades in the field of public health due to the ease of use, the cost-saving benefits, the speed of the data collection process, and the accessibility of a potentially true representative population. Although these platforms offer many advantages to researchers, significant drawbacks exist, such as poor data quality, that threaten the reliability and validity of the study. Previous studies have examined data quality concerns, but differences in results arise due to variations in study designs, disciplinary contexts, and the platforms being investigated. Therefore, this study …


Effects Of A Novel Botanical Supplement On Glycemic Variability And Postprandial Glucose Response, Nicole Stevens Apr 2023

Effects Of A Novel Botanical Supplement On Glycemic Variability And Postprandial Glucose Response, Nicole Stevens

Oxford ICSB

Mulberry leaf extract high in the iminosugar 1-deoxynojirimycin (DNJ) has been shown in previous studies to inhibit glycosidase enzyme activity. A novel supplement including mulberry leaf extract, berberine and cinnamon extract was evaluated in a two-cohort study using endpoints of glycemic variability, postprandial glucose response, fasting glucose, fasting insulin, and safety markers. In the first cohort (n=15), these endpoints were determined over two weeks by continuous glucose monitoring (CGM) and blood/urine analyses in healthy adults. Approximately half of the participants (n=7) took a dosage of 250 mg prior to each meal, and the other participants (n=8) took 500 mg before …


Nutrition Knowledge Of Young Adults: How Has K-12 Education Affected The Health Of Young Adults In 2023, Anna Polo Apr 2023

Nutrition Knowledge Of Young Adults: How Has K-12 Education Affected The Health Of Young Adults In 2023, Anna Polo

Scholars Day Conference

Background: Nutrition knowledge is very important in order to live a healthy lifestyle and to positively impact overall health. There is research studying the effects of nutrition education and that affects students involved in K-12 schooling, but there is a lack of research following those students beyond the classroom and to their young adult years.

Objective: The researcher’s goal was to better understand how much young adults know about basic nutrition from previous education, if different types of schooling (public, private, homeschool, etc.) taught nutrition related classes/lessons, and if different geographical regions provided nutrition education.

Design: the design was a …


University Students' Understanding Of The Endocannabinoid System And Its Relevance To Nutrition, Brittney Burford, Allyson Melton, Robbie Otero Apr 2023

University Students' Understanding Of The Endocannabinoid System And Its Relevance To Nutrition, Brittney Burford, Allyson Melton, Robbie Otero

Scholars Day Conference

The Endocannabinoid System (ECS) is a complex cell-signaling system that was identified in 1988, the ECS is the largest receptor system and regulator of homeostasis. Endogenous cannabinoids, or endocannabinoids, are naturally occurring, lipid-based neurotransmitters. Neurotransmitters are chemical messengers in the body that send signals between nerve cells. The ECS system regulates and controls many of our most critical bodily functions such as learning, memory, emotional processing, sleep, temperature control, inflammatory immune responses, and appetite. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most known phytocannabinoids. Phytocannabinoids are plant byproducts that closely mimic cannabinoids and have adverse effects on the body. Endogenous …


The Demographic Shift Of Males And Females In Veterinary Medicine, Dalton Tatum, Eddy Patterson, Mia C. Ratliff Apr 2023

The Demographic Shift Of Males And Females In Veterinary Medicine, Dalton Tatum, Eddy Patterson, Mia C. Ratliff

ATU Research Symposium

The workforce in veterinary medicine saw a gender shift from a male dominated field towards women in the present day. This research aimed to determine why this shift occurred through demographic analysis and surveys to different job types in this career path. By using this data, the group determined that one of the biggest impacts of the shift is due to the very component that makes veterinary medicine such a tough field, and it is located at the graduate school entry level . The competitiveness level is intertwined through all of the data and leads to the conclusion that females …


Investigating Differences In Iga Antibody Response Against Aspergillus Fumigatus In Wild Type And Tlr7 Protein Deficient Mice, Courtney Folk Apr 2023

Investigating Differences In Iga Antibody Response Against Aspergillus Fumigatus In Wild Type And Tlr7 Protein Deficient Mice, Courtney Folk

Student Academic Conference

Aspergillus fumigatus is a commonly inhaled, respiratory fungal pathogen and an allergen found in flooded indoor environments, household dust, soil, and plant matter. While a competent immune system effectively clears the inhaled fungus, this same fungus poses a significant threat to weakened immune systems due to its potential to invade the lungs, bloodstream and brain tissue. The mouse genome is 99% similar to the human genome and can serve effectively model the effects of inhaled A. fumigatus (Guénet, 2005). Antibodies play a crucial role in neutralizing pathogens and in mediating an allergic response. In this study, we will investigate the …


The Effect Of Masks On Allergic Rhinitis Symptoms Related To Ragweed And Its Influence On College Students, Katherine Knutte Apr 2023

The Effect Of Masks On Allergic Rhinitis Symptoms Related To Ragweed And Its Influence On College Students, Katherine Knutte

Scholar Week 2016 - present

BACKGROUND: This study explored the effect of masks on allergic rhinitis related to ragweed. Research has been shown that surgical and KN95 masks reduce allergic symptoms due to dust, pollen, and ragweed. A study in Israel found a strong correlation was between wearing a KN95 and reducing severe allergic rhinitis symptoms related to nasal symptoms and another study focusing on pollen supported this finding. Lastly, a previous study on ragweed found that all nasal symptoms improved, and ocular symptoms remained unchanged.

METHODS: This was a qualitative study involving twenty college students aged 18 to 25 from Olivet Nazarene …


Animal-Assisted Green Care Farming For Patients With Traumatic Brain Injury, Alex Sargsyan Apr 2023

Animal-Assisted Green Care Farming For Patients With Traumatic Brain Injury, Alex Sargsyan

Epsilon Sigma at-Large Research Conference

Animal-Assisted Green Care Farming for Patients with Traumatic Brain Injury

Purpose

To examine the effects of Animal Assisted Therapies with Farm Animals (AATF) with domesticated ducks on depression and anxiety.

Aim

The proposed study will use single-group time series design and collect survey data to explore the changes in anxiety and depression in patients exposed to AATF. The study will be guided by the Self-Efficacy Theory. The study will involve 30 patients with TBI living in The Crumley House Rehabilitation Center in Limestone, TN.

Hypothesis. Engaging in AATF with domesticated ducks will be associated with decrease in anxiety and depression. …


Social Media’S Influence On College Students’ Recognition Of Inaccurate Nutrition Information, Meghan Olthoff Apr 2023

Social Media’S Influence On College Students’ Recognition Of Inaccurate Nutrition Information, Meghan Olthoff

Scholar Week 2016 - present

Background

Basch et al. (2018) found that 74% (n=190) of students indicated that they would often or always use the internet for health information. Nutrition literacy is an important aspect of health literacy. Health literacy is defined as the skills or ability needed to comprehend and apply nutrition or health information (Svendsen et al., 2021). Nutrition misinformation can be harmful to an individual’s wellbeing because of the fallible, misleading, and erroneous content (Wansink, 2006). The purpose of this study was to explore students’ knowledge as it pertains to the inaccurate nutritional information found within social media.

Methods

A …


The Invisible Epidemic: A Concussion Assessment Among University Faculty And Staff, Emily R. Brown, Jacqueline D. Villanueva Arevalo Apr 2023

The Invisible Epidemic: A Concussion Assessment Among University Faculty And Staff, Emily R. Brown, Jacqueline D. Villanueva Arevalo

Student Scholar Showcase

Background: The present body of research is deficient, and institutions frequently lack defined return-to-learn policies for students who have incurred or been diagnosed with a mild traumatic brain injury (mTBI)/concussion.

Purpose: This research study aims to determine the level of knowledge and awareness university faculty and staff currently have at a private university in the Mid-Atlantic Region.

Participants: 64 collegiate faculty and academic staff

Methods: A Cross-sectional, web-based Faculty and Staff Concussion Awareness and Knowledge survey was completed by participants, consisting of 9 demographic, 21 Likert Scale, and 1 multiple-option question.

Results: Initial descriptive and frequency statistics of the 64 …


Beyond The Bmi: Expanding Quantitative Methods To Study Health For All Bodies, Kieran Chase, Daniel Oron Apr 2023

Beyond The Bmi: Expanding Quantitative Methods To Study Health For All Bodies, Kieran Chase, Daniel Oron

OHSU-PSU School of Public Health Annual Conference

The public health field is beginning to reckon with its role in perpetuating and reinforcing systemic anti-fatness. Emerging evidence for the devastating health impacts of stigma call into question decades of research and policy that labels the size of people’s bodies as diseased. However, even as we acknowledge the harmful effects of stigma, the field is materially and institutionally invested in a health paradigm that centers weight loss and size-related proxies for health, such as the BMI. Public health scholars interested in questions related to nutrition, chronic disease, and exercise must begin to expand their research focus to imagine non-stigmatizing …


Does Sph Curricula Promote ‘Health Equity’, Reproduce Injustice, Or Both?, Jesse Yarnold Apr 2023

Does Sph Curricula Promote ‘Health Equity’, Reproduce Injustice, Or Both?, Jesse Yarnold

OHSU-PSU School of Public Health Annual Conference

Does SPH Curricula Promote ‘Health Equity’, Reproduce Injustice, or both?

The social justice movements of recent years (preceded by [generations of] insurmountable suffering) have facilitated a collective recognition of the systemic effects of racism and epistemic violence. Despite the ambitious and well-intentioned vision of “health equity” as defined by epidemiologic scholarship - progress is slow and injustices prevail.

Students, scholars, and researchers of ‘Public Health’ are uniquely positioned to imagine and create innovative ways of understanding and addressing the harmful inequities and injustices perpetuated by white settler colonialism. I argue that Academic institutions delivering Public Health education are uniquely positioned …


Reproductive Health In America: A History Of Patriarchal Control, Hailey Mccool Mar 2023

Reproductive Health In America: A History Of Patriarchal Control, Hailey Mccool

Undergraduate Research Conference

The United States is often referred to as the land of opportunity and the home of the free, yet today, those who challenge the patriarchal system are not treated fairly or equitably. Historically, from owning land to voting women have fought for the same rights enjoyed by men. The effort of early feminist movements paved the way for the Supreme Court to protect women’s reproductive rights through Roe v. Wade. For decades, women were able to make a choice regarding their reproductive health. However, in just the past year (2022), the Supreme Court ruled to strike down Roe v. …


Suicidality Among College Students From 2000 To 2022: Findings From The National College Health Assessment, Jackson Gieger, Khanh Bui Dr. Mar 2023

Suicidality Among College Students From 2000 To 2022: Findings From The National College Health Assessment, Jackson Gieger, Khanh Bui Dr.

Seaver College Research And Scholarly Achievement Symposium

With suicide being the second leading cause of death for college students, research concerning suicidality is imperative. The National College Health Assessment (NCHA), conducted by the American College Health Association (ACHA) each spring and fall semester since 2000, asks questions regarding suicide ideation and suicide attempts. There have been three versions of NCHA: NCHA-I (spring 2000 - spring 2008), NCHA-II (fall 2008 - spring 2019), and NCHA-III (fall 2019 - present). The analysis of NCHA-I and NCHA-II was limited due to the wording of the questions being different in the fall and spring. This leads to difficulty in comparing data …


Engaging Youth In The Development, Implementation, An Evaluation Of Sexual And Reproductive Health Programs, Pam Drake, Kristin Kennedy Mar 2023

Engaging Youth In The Development, Implementation, An Evaluation Of Sexual And Reproductive Health Programs, Pam Drake, Kristin Kennedy

National Youth Advocacy and Resilience Conference

This session will introduce the use of a group concept mapping process to create a conceptual model for engaging youth in sexual and reproductive health programming – particularly BIPOC LGBTQ+ youth and young men of color. We will walk through the gcm process, present the model, and explore ways to apply the model in various situations.


Testing Extraction Of Dna From Lipid-Rich Tissues Using Various Reagents And Commercially Available Kits, Ryan V. Powers, Walker C. Kay, Jonathon C. Reynolds, Nathaniel E. Hill, Cole J. Farnsworth, Molly E. Henley, Alfred B. Amendolara, Noah D. Boekweg, John A. Kriak, Kyle B. Bills, David W. Sant Feb 2023

Testing Extraction Of Dna From Lipid-Rich Tissues Using Various Reagents And Commercially Available Kits, Ryan V. Powers, Walker C. Kay, Jonathon C. Reynolds, Nathaniel E. Hill, Cole J. Farnsworth, Molly E. Henley, Alfred B. Amendolara, Noah D. Boekweg, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

No abstract provided.


The Current State Of Underrepresented Osteopathic Minorities In Competitive Specialties, Emmanuel Oyalabu, Steve Guzman, Dashon Eure, Ezenna Obilor Feb 2023

The Current State Of Underrepresented Osteopathic Minorities In Competitive Specialties, Emmanuel Oyalabu, Steve Guzman, Dashon Eure, Ezenna Obilor

Annual Research Symposium

It is well documented that barriers exist for underrepresented minorities to enter the field of medicine and even more competitive residencies. As defined by the NRMP, competitive specialties include but are not limited to Interventional Radiology, Orthopedic Surgery, Plastic Surgery, Radiation Oncology, Vascular Surgery, Neurosurgery, Dermatology, and Otornylogy (NRMP-AMA). A large number of osteopathic medical school graduates have a history of going into primary care specialties because many osteopathic medical schools have a primary care focus (Primary Care- Osteopathic Medicine). The emphasis on primary care, whether intentional or not, can foster a less-than-advantageous environment for underrepresented minority students (URM), pursuing …


The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang Feb 2023

The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang

Annual Research Symposium

No abstract provided.


Comparison Of Confidence Levels From Dental Student-To-Student Injections, Emily Lear Feb 2023

Comparison Of Confidence Levels From Dental Student-To-Student Injections, Emily Lear

Annual Research Symposium

No abstract provided.


Association Of Asthma With Oral Health In Different Age Groups, Jody Chiang, Amir Mohajeri, Joseph Cheever, Frank Licari, Man Hung Feb 2023

Association Of Asthma With Oral Health In Different Age Groups, Jody Chiang, Amir Mohajeri, Joseph Cheever, Frank Licari, Man Hung

Annual Research Symposium

No abstract provided.


The Factors That Influence Clinicians To Choose Rural Settings To Deliver Health Services, Julia Mattingly Jan 2023

The Factors That Influence Clinicians To Choose Rural Settings To Deliver Health Services, Julia Mattingly

Posters-at-the-Capitol

Years before the COVID-19 pandemic brought on a health care shortage in the United States, its rural areas were already struggling to obtain and attract primary care medical practitioners. The federal government has designed many programs with the intent of exposing clinicians to life in rural areas, but few have been successful at keeping medical practitioners in the long-term. Clinicians who are recruited to rural areas via loan repayment programs or other short-lived incentives often leave after only a few years.

In order to learn more about this long-running health policy problem, we set out to study the factors that …


Considerations In The Management Of Juvenile Absence Epilepsy In Pregnancy And In Females Of Childbearing Age, Casey Brew Jan 2023

Considerations In The Management Of Juvenile Absence Epilepsy In Pregnancy And In Females Of Childbearing Age, Casey Brew

Capstone Showcase

JAE is an epilepsy syndrome that typically requires lifelong AED treatment, and valproic acid or lamotrigine is considered first line to manage the spectrum of associated seizures. In females with JAE who become pregnant, there exist risks both from having uncontrolled seizures and from taking AEDs during the pregnancy. Valproic acid carries the highest risks to the fetus but is the most effective in controlling the seizure types seen with JAE. Folic acid supplementation has shown to mitigate some but not all of the fetal risks from valproic acid. Limited guidance from professional organizations exists for management of females of …