Convergence Of Human And Old World Monkey Gut Microbiomes Demonstrates The Importance Of Human Ecology Over Phylogeny, 2019 Northwestern University
Convergence Of Human And Old World Monkey Gut Microbiomes Demonstrates The Importance Of Human Ecology Over Phylogeny, Katherine R. Amato, Elizabeth K. Mallott, Daniel Mcdonald, Nathaniel J. Dominy, Tony Goldberg, Joanna E. Lambert, Larissa Swedell, Jessica L. Metcalf, Andres Gomez, Gillian A. O. Britton, Rebecca M. Stumpf, Steven R. Leigh, Rob Knight
Publications and Research
Comparative data from non-human primates provide insight into the processes that shaped the evolution of the human gut microbiome and highlight microbiome traits that differentiate humans from other primates. Here, in an effort to improve our understanding of the human microbiome, we compare gut microbiome composition and functional potential in 14 populations of humans from ten nations and 18 species of wild, non-human primates.
Contrary to expectations from host phylogenetics, we find that human gut microbiome composition and functional potential are more similar to those of cercopithecines, a subfamily of Old World monkey, particularly baboons, than to those ...
Allometric Variation In Modern Humans And The Relationship Between Body Proportions And Elite Athletic Success, Tesla A. Monson, Marianne F. Brasil, Leslea J. Hlusko
In many sports, greater height and arm span are purportedly linked to athletic success. While variation in body proportions has been explored across an array of scientific disciplines, studies focusing on humans of tall stature outside of clinical cases are limited. We investigated body size proportions in a sample of elite athletes, employing data on recruits for the National Basketball Association (NBA, n=2,990), mixed martial arts (MMA) fighters (mixed-sex, n=1,284), as well as a control sample of healthy young adults who are not professional athletes, represented here by male (n=4,082) and female (n=1 ...
Using Machine Learning To Classify Extant Apes And Interpret The Dental Morphology Of The Chimpanzee-Human Last Common Ancestor, 2019 Western Washington University
Using Machine Learning To Classify Extant Apes And Interpret The Dental Morphology Of The Chimpanzee-Human Last Common Ancestor, Tesla A. Monson, David W. Armitage, Leslea J. Hlusko
Machine learning is a formidable tool for pattern recognition in large datasets. We developed and expanded on these methods, applying machine learning pattern recognition to a problem in paleoanthropology and evolution. For decades, paleontologists have used the chimpanzee as a model for the chimpanzee-human last common ancestor (LCA) because they are our closest living primate relative. Using a large sample of extant and extinct primates, we tested the hypothesis that machine learning methods can accurately classify extant apes based on dental data. We then used this classification tool to observe the affinities between extant apes and Miocene hominoids. We assessed ...
Analysis Of Two Human Skeletons From Smith's Fort, Bermuda, 2019 College of William and Mary
Analysis Of Two Human Skeletons From Smith's Fort, Bermuda, Michael L. Blakey, Autumn Barrett
No abstract provided.
Sex, Energy, Well-Being And Low Testosterone: An Exploratory Survey Of U.S. Men’S Experiences On Prescription Testosterone, 2019 University of Nevada, Las Vegas
Sex, Energy, Well-Being And Low Testosterone: An Exploratory Survey Of U.S. Men’S Experiences On Prescription Testosterone, Alex A. Straftis, Peter B. Gray
Anthropology Faculty Publications
Prescription testosterone sales in the United States have skyrocketed in the last two decades due to an aging population, direct-to-consumer advertising, and prescriber views of the benefits and risks to testosterone, among other factors. However, few studies have attempted to directly examine patient experiences on prescription testosterone therapy. The present exploratory study involved an online self-report survey of U.S. testosterone patients who were at least 21 years of age. The primary focus was on patient perspectives concerning motivations leading to the initiation of testosterone therapy and the perceived effects of treatment. Responses to open-ended questions drew upon a coding ...
Successful Enrichment And Recovery Of Whole Mitochondrial Genomes From Ancient Human Dental Calculus, 2019 University of Oklahoma
Successful Enrichment And Recovery Of Whole Mitochondrial Genomes From Ancient Human Dental Calculus, Andrew T. Ozga, Maria A. Nieves-Colon, Tanvi P. Honap, Krithivasan Sankaranarayanan, Courtney A. Hofman, George R. Milner, Cecil M. Lewis Jr., Anne C. Stone, Christina Warinner
Archaeological dental calculus is a rich source of host‐associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive analysis of conventional skeletal remains is not permitted. Here we investigate the preservation of human mitochondrial DNA (mtDNA) in archaeological dental calculus and its potential for full mitochondrial genome (mitogenome) reconstruction in maternal lineage ancestry analysis.
Origins Of An Unmarked Georgia Cemetery Using Ancient Dna Analysis, 2019 University of Oklahoma
Origins Of An Unmarked Georgia Cemetery Using Ancient Dna Analysis, Andrew T. Ozga, Raul Y. Tito, Brian M. Kemp, Hugh Matternes, Alexandra J. Obregon-Tito, Leslie Neal, Cecil M. Lewis Jr.
Determining the origins of those buried within undocumented cemeteries is of incredible importance to historical archaeologists and, in many cases, the nearby communities. In the case of Avondale Burial Place, a cemetery in Bibb County, Georgia, in use from 1820 to 1950, all written documentation of those interred within it has been lost. Osteological and archaeological evidence alone could not describe, with confidence, the ancestral origins of the 101 individuals buried there. In the present study, we used ancient DNA extraction methods in well-preserved skeletal fragments from 20 individuals buried in Avondale Burial Place to investigate the origins of the ...
Comparison Of Two Ancient Dna Extraction Protocols For Skeletal Remains From Tropical Environments, 2019 Arizona State University
Comparison Of Two Ancient Dna Extraction Protocols For Skeletal Remains From Tropical Environments, Maria A. Nieves-Colon, Andrew T. Ozga, William J. Pestle, Andrea Cucina, Vera Tiesler, Travis W. Stanton, Anne C. Stone
The tropics harbor a large part of the world's biodiversity and have a long history of human habitation. However, paleogenomics research in these climates has been constrained so far by poor ancient DNA yields. Here we compare the performance of two DNA extraction methods on ancient samples of teeth and petrous portions excavated from tropical and semi‐tropical sites in Tanzania, Mexico, and Puerto Rico (N = 12).
Materials and Methods
All samples were extracted twice, built into double‐stranded sequencing libraries, and shotgun sequenced on the Illumina HiSeq 2500. The first extraction protocol, Method D, was previously designed ...
An Investigation Into Human To Dog Attachment Systems And Their Influence On The Degree Of Aversion Used In Training, 2019 University of Nevada, Las Vegas
An Investigation Into Human To Dog Attachment Systems And Their Influence On The Degree Of Aversion Used In Training, Shelly Volsche
Shelly L. Volsche
The purpose of my Master’s Thesis research is to determine if and what type of relationship exists between owner-to-dog attachment levels and the degree of aversion used in dog training. I also sought to determine if owner characteristics such as parental status, income, gender, and the like influenced the degree of aversion used. My primary hypothesis is that a negative correlation exists between attachment to one’s dog and aversion used in training. That is, as attachment scores increase, aversion scores decrease. In addition to testing this hypothesis, I collected data to determine if there are correlations between the ...
Childhood Stress At Rinconada Alta (Ad 1470-1532): An Examination Of Linear Hypoplastic Enamel Defects On The Central Coast Of Peru, 2019 The University of Western Ontario
Childhood Stress At Rinconada Alta (Ad 1470-1532): An Examination Of Linear Hypoplastic Enamel Defects On The Central Coast Of Peru, Jessica Lacerte
Electronic Thesis and Dissertation Repository
This MA thesis investigates non-specific childhood stress at Rinconada Alta through the analysis of linear enamel hypoplastic defects (LEH). Dental casts were taken from a sample of teeth from predominantly Inca-period, Yschma remains (with some admixture of the Late Intermediate period burials). The sample consists of 10 adult females, 11 adult males, and 5 adolescents of indeterminate sex with fully occluded adult teeth (with the exception of the third molars). This thesis employs Scanning Electron Microscopy (SEM), which increases the visibility of linear defects, to determine the frequency, age, and duration at which metabolic disruption affected enamel growth of the ...
The Archaeology Of Mississippian Vulnerability And Resilience In The New Madrid Seismic Zone, 2019 University of Arkansas, Fayetteville
The Archaeology Of Mississippian Vulnerability And Resilience In The New Madrid Seismic Zone, Michelle Megan Rathgaber
Theses and Dissertations
This work examines the vulnerability and resilience of Mississippian people in the Central Mississippi Valley to the large-scale New Madrid seismic zone earthquakes of the late15th to early 16th century. This is done using the theory of eventful archaeology/anthropology to look at cultural materials both before and after an event (such as an earthquake and sand blows) to look for evidence of changes to the schema and resources on which a society relies. If changes are present, the event can be labeled as such, if there are no changes, it means that the society affected did not see the ...
Probability, Populations, Phylogenetics And Hominin Speciation, 2019 San Francisco State University
Probability, Populations, Phylogenetics And Hominin Speciation, Niccolo Caldararo
Human Biology Open Access Pre-Prints
A number of recent articles have appeared on the hominin Denisova fossil remains. Many of them focus on attempts to produce DNA sequences from the extracted samples. Often these project mtDNA sequences from the fossil remains of a number of Neandertal fossils and the Denisovans in an attempt to understand the evolution of Mid Pleistocene human ancestors. These papers, introduce a number of problems in the interpretation of speciation in hominins. One concerns the degradation of the ancient DNA and its interpretation as authentic genetic information. Another concerns the idea of “species” versus that of “population” and the use of ...
A Geospatial Recipe For Identifying Social Values And Fragmentation Issues Of The Friends Of The Dunes Land Trust, 2019 Humboldt State University
A Geospatial Recipe For Identifying Social Values And Fragmentation Issues Of The Friends Of The Dunes Land Trust, Buddhika Madurapperuma, Jess Barger, Melissa Collin, Christine Emerson, Sean Fleming, Brian Murphy
Humboldt Journal of Social Relations
The beach and coastal sand dunes comprise a dynamic and fragile ecosystem that provides a bounty of ecological services. These lands provide protection from coastal erosion and sea level rise, and are home to a rich biodiversity of plant and animal species in addition to their recreational value. The Humboldt Coastal Nature Center and the surrounding coastal dunes (HCNC) are man-aged as a land trust by Friends of the Dunes (FOD). FOD prioritize the restoration of dune habitats and encourages public involvement through community supported education and stewardship programs, guided nature tours, and naturalist training programs. The faculty, students, and ...
Mass Grave Detection With The Use Of Geophysics, 2019 University of Tennessee, Knoxville
Mass Grave Detection With The Use Of Geophysics, Madelyn M. Knaub
Chancellor’s Honors Program Projects
No abstract provided.
Experimental Immunology And The Potential For Osteopathological Reconstructions : Pursuing An Experimental Foundation For The Skeletal Inflammatory Index., Megan Elizabeth Duncanson
Electronic Theses and Dissertations
Individuals who mount a strong inflammatory response may produce a shift in the systemic levels of inflammatory mediators, which may lead to a potential hyper-inflammatory phenotype (HIP). Systemic inflammation can increase severity in local inflammatory processes detected in bone lesions. This thesis investigated in vitro if human immune cells pre-treated with inflammatory inducers would affect the inflammatory response against Porphyromonas gingivalis or Staphylococcus aureus (both associated with osteological lesions). We exposed human peripheral blood mononuclear cells to bacterial lysates, or pro-inflammatory cytokines. Sequentially, we exposed the same culture to either P. gingivalis or S. aureus. The final expression of TNFα ...
Disease And De Soto: A Bioarchaeological Approach To The Introduction Of Malaria To The Southeast Us, 2019 University of Arkansas, Fayetteville
Disease And De Soto: A Bioarchaeological Approach To The Introduction Of Malaria To The Southeast Us, Kelly Marie Schaeffer
Theses and Dissertations
It is well known through documentation in historical accounts that numerous diseases were introduced to the Americas during the time of Spanish and French exploration. Diseases such as smallpox, measles and yellow fever have been credited in playing a role in the Spanish conquest of the New World through drastic Native American population decline. Many researchers have studied the biological consequences of European contact, some using direct skeletal analyses to study changes in Native American health and disease. However, one major population disease that has not been part of these discussions is malaria. This is mostly due to the current ...
The Archaeology Of Leetown Hamlet: Households And Consumer Behavior In The Arkansas Ozarks, 2019 University of Arkansas, Fayetteville
The Archaeology Of Leetown Hamlet: Households And Consumer Behavior In The Arkansas Ozarks, Victoria Ann Jones
Theses and Dissertations
The hamlet of Leetown, located within Pea Ridge Military Park is the focus of this thesis. The Leetown hamlet played a role in the Battle of Pea Ridge and eventually disappeared before Pea Ridge National Military Park’s establishment in the 1960s. Shortly after the establishment of the Park, archeological investigations began. The resulting archeological investigations from 1962 to 2017 provided a glimpse into the lives of the families of Leetown hamlet within the rural Ozarks. This is an archeological investigation that focuses on establishing the date and function of the buildings within the hamlet as well as the consumer ...
Identifying Cystic Fibrosis (Cf) Skeletally: A Proposed Differential Diagnosis, 2019 University of Tennessee, Knoxville
Identifying Cystic Fibrosis (Cf) Skeletally: A Proposed Differential Diagnosis, Clare Remy
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
Cystic fibrosis (CF) is an inherited disorder that affects the mucosal lining of the lungs and digestive system due to a defective gene that causes blockages of tubes, ducts, and passageways. The type of mutation correlates with the severity of the condition, but with modern medicine individuals can live into their 50s. We propose a differential diagnosis for identifying CF in the skeleton based on bony pathologies that occur in higher frequency in CF patients. CF patients exhibit chronic sinusitis, clubbing of hands and feet, vertebral fractures/collapse and abnormal curvature, significantly shorter stature, lower bone density, rib fractures, and ...
Evolution Of Endurance Running Genes Across Primates, 2019 CUNY Hunter College
Evolution Of Endurance Running Genes Across Primates, Natalia T. Grube
School of Arts & Sciences Theses
The endurance running hypothesis has emerged as a key idea to explain several unique anatomical, physiological, and genetic features of modern humans—among these features is the evolution of ACTN3 (Bramble & Lieberman 2004, Nature), a gene linked to human athletic performance. An additional gene linked to human endurance performance is ACE. Because endurance running is a uniquely human trait, I predicted that ACE and ACTN3 genes would be evolving adaptively in the human lineage when examined in a wider primatological framework. To test this I compiled ACE and ACTN3 genes from 14 primate species and phylogenetically tested if these genes ...
Diet Of The Prehistoric Population Of Rapa Nui (Easter Island, Chile) Shows Environmental Adaptation And Resilience, Catrine L. Jarmine, Thomas Larsen, Terry L. Hunt, Carl P. Lipo, Reidar Solsvik, Natalie Wallsgrove, Cassie Ka'apu-Lyons, Hilary G. Close, Brian N. Popp
Objectives: The Rapa Nui “ecocide” narrative questions whether the prehistoric population caused an avoidable ecological disaster through rapid deforestation and over-exploitation of natural resources. The objective of this study was to characterize prehistoric human diets to shed light on human adaptability and land use in an island environment with limited resources.
Materials and methods: Materials for this study included human, faunal, and botanical remains from the archaeological sites Anakena and Ahu Tepeu on Rapa Nui, dating from c. 1400 AD to the historic period, and modern reference material. We used bulk carbon and nitrogen isotope analy- ses and amino acid ...