Physical Therapy Commons^™

Task Effects On Functional Connectivity Measures After Stroke, Kaleb Vinehout, Sheila M. Schindler-Ivens, Jeffrey R. Binder, Brian D. Schmit

Physical Therapy Faculty Research and Publications

Understanding the effect of task compared to rest on detecting stroke-related network abnormalities will inform efforts to optimize detection of such abnormalities. The goal of this work was to determine whether connectivity measures obtained during an overt task are more effective than connectivity obtained during a “resting” state for detecting stroke-related changes in network function of the brain. This study examined working memory, discrete pedaling, continuous pedaling and language tasks. Functional magnetic resonance imaging was used to examine regional and inter-regional brain network function in 14 stroke and 16 control participants. Independent component analysis was used to identify 149 regions …

Disparities In The Allocation Of Inpatient Physical And Occupational Therapy Services For Patients With Covid-19, Sarah Jolley, Amy Nordon-Craft, Melissa P. Wilson, Kyle Ridgeway, Michelle R. Rauzi, Jacob J. Capin, Lauren M. Heery, Jennifer Stevens-Lapsley, Kristine M. Erlandson

Physical Therapy Faculty Research and Publications

Background

Survivors of the novel coronavirus (COVID-19) experience significant morbidity with reduced physical function and impairments in activities of daily living. The use of in-hospital rehabilitation therapy may reduce long-term impairments.

Objective

To determine the frequency of therapy referral and treatment amongst hospitalized COVID-19 patients, assess for disparities in referral and receipt of therapy, and identify potentially modifiable factors contributing to disparities in therapy allocation.

Design, Setting and Participants

Retrospective cohort study using data collected from the University of Colorado Health Data Compass data warehouse assessing therapy referral rates and estimated delivery based on available administrative billing.

Measurements

Multivariable logistic …

Developing Peri-Operative Rehabilitation In Degenerative Cervical Myelopathy [Ao Spine Recode-Dcm Research Priority Number 6]: An Unexplored Opportunity?, Timothy F. Boerger, Allison S. Hyngstrom, Julio C. Furlan, Sukhvinder Klasi-Ryan, Armin Curt, Brian K. Kwon, Shekar N. Kurpad, Michael G. Fehlings, James S. Harrop, Bizhan Aarabi, Vafa Rahimi-Movaghar, James D. Guest, Jefferson R. Wilson, Benjamin M. Davies, Mark R. N. Kotter, Paul A. Koljonen

Physical Therapy Faculty Research and Publications

Study Design

Narrative review.

Objective

Degenerative cervical myelopathy is one of the most frequent impairments of the spinal cord encountered internationally in adults. Currently, surgical decompression is the recommended treatment for people with DCM (PwCM) presenting with moderate to severe symptoms or neurological deficits. However, despite surgical intervention, not all patients make a complete recovery due to the irreversible tissue damage within the spinal cord. The objective of this review is to describe the state and gaps in the current literature on rehabilitation for PwCM and possible innovative rehabilitation strategies.

Methods

Literature search.

Results

In other neurological disorders such as …

Muscle-Specific Contributions To Lower Extremity Net Joint Moments While Squatting With Different External Loads, Kristof Kipp, Hoon Kim, William I. Wolf

Exercise Science Faculty Research and Publications

The purpose of this study was to determine muscle-specific contributions to lower extremity net joint moments (NJMs) during squats with different external loads. Nine healthy subjects performed sets of the back squat exercise with 0, 25, 50, and 75% of body mass as an added external load. Motion capture and force plate data were used to calculate NJMs and to estimate individual muscle forces via static optimization. Individual muscle forces were multiplied by their respective moment arms to calculate the resulting muscle-specific joint moment. Statistical parametric mapping (α = 0.05) was used to determine load-dependent changes in the time series …

Blood Flow Restriction Training After Patellar Instability (Brains Trial), Benjamin D. Brightwell, Austin V. Stone, Xiaojuan Li, Peter A. Hardy, Katherine L. Thompson, Brian W. Noehren, Cale A. Jacobs

Orthopaedic Surgery and Sports Medicine Faculty Publications

Background

Patellar instability is a common and understudied condition that disproportionally affects athletes and military personnel. The rate of post-traumatic osteoarthritis that develops following a patellar dislocation can be up to 50% of individuals 5–15 years after injury. Conservative treatment is the standard of care for patellar instability however, there are no evidence-informed rehabilitation guidelines in the scientific literature. The purpose of this study is to assess the effectiveness of blood-flow restriction training (BFRT) for patellar instability. Our hypotheses are that this strategy will improve patient-reported outcomes and accelerate restoration of symmetric strength and knee biomechanics necessary to safely return …

Long-Lasting Impairments In Quadriceps Mitochondrial Health, Muscle Size, And Phenotypic Composition Are Present After Non-Invasive Anterior Cruciate Ligament Injury, Steven M. Davi, Ahram Ahn, Mckenzie S. White, Timothy A. Butterfield, Kate Kosmac, Oh Sung Kwon, Lindsey K. Lepley

Center for Muscle Biology Faculty Publications

Introduction: Despite rigorous rehabilitation aimed at restoring muscle health, anterior cruciate ligament (ACL) injury is often hallmarked by significant long-term quadriceps muscle weakness. Derangements in mitochondrial function are a common feature of various atrophying conditions, yet it is unclear to what extent mitochondria are involved in the detrimental sequela of quadriceps dysfunction after ACL injury. Using a preclinical, non-invasive ACL injury rodent model, our objective was to explore the direct effect of an isolated ACL injury on mitochondrial function, muscle atrophy, and muscle phenotypic transitions.

Methods: A total of 40 male and female, Long Evans rats (16-week-old) were exposed to …

Laterality Of The Activation Of The Vastus Lateralis Muscle In Females With Parkinson's Disease During The Medication State Compared With Healthy Controls, Yuichi Nishikawa, Kohei Watanabe, Tetsuya Takahashi, Noriaki Maeda, Hirofumi Maruyama, Shinobu Tanaka, Allison S. Hyngstrom

Physical Therapy Faculty Research and Publications

This study quantified the laterality of motor unit activation properties in females with Parkinson’s disease during force production (low to high-intensity contraction) using high-density surface electromyography. Sixteen females with Parkinson’s disease (age = ± 7.6 years, disease duration = 4.9 ± 5.1 years) and 14 healthy female subjects (age = 68.6 ± 3.6 years) performed submaximal ramp-up contractions during isometric knee extension. High-density surface electromyography signals were recorded from both vastus lateralis muscles. The level of heterogeneity was calculated in the spatial distribution patterns of the high-density surface electromyography signals to determine the modified entropy, coefficient of variation of the …

Trait Energy And Fatigue May Be Connected To Gut Bacteria Among Young Physically Active Adults: An Exploratory Study, Ali Boolani, Karyn M. Gallivan, Kristin S. Ondrak, Courtney J. Christopher, Hector F. Castro, Shawn R. Campagna, Christopher M. Taylor, Meng Luo, Scot E. Dowd, Matthew Lee Smith, Lauri O. Byerley

School of Medicine Faculty Publications

Recent scientific evidence suggests that traits energy and fatigue are two unique unipolar moods with distinct mental and physical components. This exploratory study investigated the correlation between mental energy (ME), mental fatigue (MF), physical energy (PE), physical fatigue (PF), and the gut microbiome. The four moods were assessed by survey, and the gut microbiome and metabolome were determined from 16 S rRNA analysis and untargeted metabolomics analysis, respectively. Twenty subjects who were 31 ± 5 y, physically active, and not obese (26.4 ± 4.4 kg/m2) participated. Bacteroidetes (45%), the most prominent phyla, was only negatively correlated with PF. The second …

A Muscle Cell-Macrophage Axis Involving Matrix Metalloproteinase 14 Facilitates Extracellular Matrix Remodeling With Mechanical Loading, Bailey D. Peck, Kevin A. Murach, R. Grace Walton, Alexander J. Simmons, Douglas E. Long, Kate Kosmac, Cory M. Dungan, Philip A. Kern, Marcas M. Bamman, Charlotte A. Peterson

Center for Muscle Biology Faculty Publications

The extracellular matrix (ECM) in skeletal muscle plays an integral role in tissue development, structural support, and force transmission. For successful adaptation to mechanical loading, remodeling processes must occur. In a large cohort of older adults, transcriptomics revealed that genes involved in ECM remodeling, including matrix metalloproteinase 14 (MMP14), were the most upregulated following 14 weeks of progressive resistance exercise training (PRT). Using single-cell RNA-seq, we identified macrophages as a source of Mmp14 in muscle following a hypertrophic exercise stimulus in mice. In vitro contractile activity in myotubes revealed that the gene encoding cytokine leukemia inhibitory factor ( …

A Physical Therapy Mobility Checkup For Older Adults: Feasibility And Participant Preferences From A Discrete Choice Experiment, Dalerie Lieberz, Hannah Borgeson, Steven Dobson, Lindsey Ewings, Karen Johnson, Kori Klaysmat, Abby Schultz, Rachel Tasson, Alexandra L. Borstad

Journal of Patient-Centered Research and Reviews

Purpose: Physical performance measures, like walking speed, identify and predict preclinical mobility disability but are rarely used in routine medical care. A preventive model of care called Mobility Checkup is being designed to reduce mobility disability in older adults. This study had two purposes: 1) determine feasibility and outcomes of the Mobility Checkup, and 2) identify preferences of older adults regarding this model of care using a discrete choice experiment.

Methods: Adults over 55 years of age were recruited from the community. In the study’s first phase, participants completed a Mobility Checkup, with feasibility evaluated using 6 criteria. In the …

Visualization-Driven Time-Series Extraction From Wearable Systems Can Facilitate Differentiation Of Passive Adl Characteristics Among Stroke And Healthy Older Adults, Joby John, Rahul Soangra

Physical Therapy Faculty Articles and Research

Wearable technologies allow the measurement of unhindered activities of daily living (ADL) among patients who had a stroke in their natural settings. However, methods to extract meaningful information from large multi-day datasets are limited. This study investigated new visualization-driven time-series extraction methods for distinguishing activities from stroke and healthy adults. Fourteen stroke and fourteen healthy adults wore a wearable sensor at the L5/S1 position for three consecutive days and collected accelerometer data passively in the participant’s naturalistic environment. Data from visualization facilitated selecting information-rich time series, which resulted in classification accuracy of 97.3% using recurrent neural networks (RNNs). Individuals with …

Patient Engagement In Cosmetic Designing Of Prostheses: Current Practice And Potential Outcome Benefits, Szu-Ping Lee, Cailin Mitchell, Kenneth Repayo, Matthew Tillitt, Collin Weber, Lung-Chang Chien, Chris Doerger

Physical Therapy Faculty Research

Background: Making a prosthesis for an individual with limb loss is a highly personalized process. A currently unexplored area is whether there are tangible benefits in greater patient engagement during the cosmetic designing of their prostheses. We examined the current clinical practice of engaging patients in prosthetic cosmetic designing and identified factors associated with patient outcomes.

Methods: One hundred and four prosthetists and 28 prosthesis users were surveyed in this cross-sectional study. The question- naires covered aspects of prosthetic prescription and fabrication, users’ perceived level of engagement, and self-reported outcomes.

Regression analyses were used to examine the associations between patients’ …

Analysis Of Zero Balancing Case Studies Through An Occupational Therapy Lens, Deanna Waggy Otr, Msa, Czb, Csla

Journal of Transformative Touch

Does Zero Balancing positively impact occupational performance? This is a question many Occupational Therapists (OTs) ask when discerning if Zero Balancing (ZB) is an evidence-based treatment modality. Case studies from the book Experiencing the Power of Zero Balancing: Case Studies of Journeys to Health and Wholeness (Quarry & King, 2016) were reviewed and compared to the Occupational Therapy domain of practice to show clear evidence that each case study had a positive impact on occupational performance. A comparison chart shows a direct link between the occupational categories and documented evidence of improved occupational performance through practitioner observation and client feedback …

Kinematic Analysis Of 360° Turning In Stroke Survivors Using Wearable Motion Sensors, Masoud Abdollahi, Pranav Madhav Kuber, Michael Shiraishi, Rahul Soangra, Ehsan Rashedi

Physical Therapy Faculty Articles and Research

Background: A stroke often bequeaths surviving patients with impaired neuromusculoskeletal systems subjecting them to increased risk of injury (e.g., due to falls) even during activities of daily living. The risk of injuries to such individuals can be related to alterations in their movement. Using inertial sensors to record the digital biomarkers during turning could reveal the relevant turning alterations. Objectives: In this study, movement alterations in stroke survivors (SS) were studied and compared to healthy individuals (HI) in the entire turning task due to its requirement of synergistic application of multiple bodily systems. Methods: The motion of 28 participants (14 …

Admission Variables Predict Success In A Hybrid-Online Physical Therapist Education Program, Evan M. Pucillo, Rossniel Marinas, Christine Salmon, Vibhor Agrawal

Internet Journal of Allied Health Sciences and Practice

Purpose: Screening student applicants can be a valuable measure for hybrid-online Doctor of Physical Therapy (DPT) programs.Institutions embrace a wide variety of measurements that drive admissions decisions. However, uncertainties exist regarding the most accurate admission predictors of academic outcomes, especially among hybrid-online DPT programs. The purpose of this study was to examine predictive relationships between applicants’ admission variables and program grade point average and National Physical Therapy Examination (NPTE) performance in a cohort of entry-level hybrid-online DPT students. Methods: A retrospective cohort design and convenience sampling method was used across two entry-level hybrid-online DPT programs in the Southeastern US. Hybrid-online …

Attitudes And Beliefs Of Physical Therapist And Physical Therapist Assistant Program Directors In The United States Towards Interprofessional Education, Lawrence Ramiscal, Christopher Truelove Jr., Vahe Heboyan, Gianluca De Leo

Internet Journal of Allied Health Sciences and Practice

Purpose: To investigate the attitudes and beliefs of physical therapy (PT) and physical therapist assistant (PTA) program directors towards interprofessional education (IPE). We hypothesized that Communication and Ethics would be the most important competencies among program directors. Methods: A cross-sectional survey based on previously utilized instruments modified for the profession of PT was sent to PT and PTA program directors. One hundred sixteen responses were analyzed using frequency analysis for demographic data and non-parametric Mann-Whitney U t-test for group differences. Results: While the majority of program directors agree that IPE is important, with Communication as the most important IPE competency, …

Language Discordance And Telephone Interpretation Complicates Pain Neuroscience Education In Physical Therapy Management Of A Patient With Acute Low Back Pain, Margaret C. Burns, Tamara S. Struessel

Internet Journal of Allied Health Sciences and Practice

Purpose: Pain neuroscience education (PNE) is an intervention used for musculoskeletal pain to improve understanding of pain processes; PNE can decrease pain levels, improve function, and lower disability. Clear communication between the patient and provider is important for PNE to be an effective intervention. There is a lack of research on how a language discordance may impact that communication, and therefore the effectiveness of PNE. Purposes: 1) describe the physical therapist management of a Spanish speaking patient with acute low back pain (LBP) while using an off-site telephone interpreting service and 2) examine how PNE treatment was impacted by a …

An Appreciative Inquiry Approach To Understanding What Attracts And Retains Early-Career Therapists To Work In Community Organizations, Karina M. Dancza, Yik Ming Choi, Kaisah Amalia, Pei Shan Wong, Jia Hao Hu, Li Wen Yap

Internet Journal of Allied Health Sciences and Practice

Purpose: Community health organizations are expanding in many countries to meet the health and care needs associated with an aging population, an increase in recognition of children with developmental and mental health needs, and escalating healthcare costs. Singapore is no exception. Community organizations, however, are facing challenges in recruiting and retaining early-career therapists to these positions due to competition from acute services and a declining foreign talent pool. At the same time, early-career therapists encounter challenges during the transition from student to professional. Community organizations, therefore, need to identify what makes their organization attractive to early-career therapists and what makes …

Action Observation Training Reduces Freezing Of Gait Among Individuals With Parkinson’S Disease: A Systematic Review, Ivan Iton, Morgan Phillips, Kylie Reardon, Katlyn Scarpinella, Eileen Woodcock, James M. Smith

Internet Journal of Allied Health Sciences and Practice

Purpose: Recent evidence suggested action observation training (AOT) may benefit individuals with Parkinson’s disease (PD) experiencing freezing of gait (FoG). The purpose of this study was to determine if AOT can effectively decrease FoG among people with PD. Method: This review followed PRISMA guidelines and was registered a priori with PROSPERO. The databases PubMed, CINAHL, Cochrane Database of Systematic Reviews, PEDro and PROSPERO were searched. Inclusion criteria were randomized controlled studies, an intervention with AOT, adult subjects with PD, published in a journal, and written in English. Study quality was evaluated with the APTA Critical Appraisal Tool for …

Transformation Of The Physical Therapist Assistant (Pta): A Survey Of Current Practice And Education, Jennifer Jewell, Pamela Pologruto, Beverly Labosky, Gina Tarud

Internet Journal of Allied Health Sciences and Practice

Purpose: To find trends in utilization and practice of the physical therapist assistant (PTA) in the clinical setting and to assess current clinician views on the expected future direction for the education of the PTA. Method/Subjects: An electronic survey was sent to all accredited PT and PTA programs in United States requesting the survey be forwarded to physical therapist and physical therapist assistant faculty, alumni and clinical instructors in their geographic region for completion. Results: PTAs are a vital part of physical therapy practice. Forty percent of respondents reported that greater than 50% of direct patient interventions are typically …