Substance Abuse and Addiction Commons^™

Research Proposal: The Effects Of Therapeutic Interventions On Illicit Drug Abuse Among Homeless Adolescents, Alice Baillio, Meghan Stanley, Sarah Kroupa, Rania Ajaj, Paige Rabidoux

OUR Journal: ODU Undergraduate Research Journal

Aim: To compare case management versus community-based therapy on illicit drug abuse among homeless adolescents

Background: Homeless adolescents are at high risk for illicit drug abuse.

Methods:

• A quasi-experimental, multiple baseline time series design

• 52 sessions over a 12-month period

• Baseline assessment and survey on demographics

• Follow-up: closed-ended questionnaire (every four months)

Analysis: Repeated ANOVA test and dependent t-test

Limitations: Lack of recent evidence-based research, a small sample size, self-report data, and length of the study.

Misuse Of Novel Synthetic Opioids: A Deadly New Trend, Matthew P. Prekupec, Peter A. Mansky, Michael H. Baumann

College of Osteopathic Medicine (TUN) Publications and Research

Novel synthetic opioids (NSOs) include various analogs of fentanyl and newly emerging non-fentanyl compounds. Together with illicitly manufactured fentanyl (IMF), these drugs have caused a recent spike in overdose deaths, whereas deaths from prescription opioids have stabilized. NSOs are used as stand-alone products, as adulterants in heroin, or as constituents of counterfeit prescription medications. During 2015 alone, there were 9580 deaths from synthetic opioids other than methadone. Most of these fatalities were associated with IMF rather than diverted pharmaceutical fentanyl. In opioid overdose cases, where the presence of fentanyl analogs was examined, analogs were implicated in 17% of fatalities. Recent …

Experiences Of Postpartum Women In One Residential Treatment Facility For Substance Use Disorders: A Qualitative Case Study, Rebecca Jo Williams

Online Theses and Dissertations

A growing opioid crisis in the United States has sparked a need for gender-specific research and treatment to address unmet needs and promote positive health outcomes for both women and children. The primary purpose of this research is to provide insight into the experiences and perceptions of postpartum women with substance use disorders receiving care at one residential treatment facility. Two women, aged 22 and 27 years old, participated in semi-structured interviews designed to elicit perceptions about barriers to treatment, the value of various programs, the role of physical, social, and temporal contexts in treatment, and beliefs about the effect …

Euphoria: The Transition From Prescription Opioids To Heroin In Kentucky, Alexander Ryan Cundiff

Online Theses and Dissertations

The demand for and availability of prescription opioids has been quite prevalent in the state of Kentucky primarily since the early 1990's. But between 2010 and 2012, reformulations of opioids OxyContin and Opana, along with the passing of HB 217 and mandatory KASPER (Kentucky All Schedule Prescription Electronic Reporting) reports made the acquisition of diverted pharmaceutical opioids much more difficult. As a result, prices per pill increased and once opioids became nearly impossible to find on the streets, users then moved to another opiate, heroin. Since 2012, heroin related overdoses have increased significantly in the Bluegrass State. The purpose of …

Drug Court Versus Incarceration: Which Is More Effective?, Erin Alexander, Kathryn Apperson, Megan Flannigan, Sarah Jean, Lintag Rosalina, Jennifer Lynch, Ethan Schwartz

OUR Journal: ODU Undergraduate Research Journal

Aim: This study explores the affect drug court treatment programs have on the sobriety and employment status of the participants.

Background: Drug addiction has been an ongoing issue nationwide, and with addiction comes drug related crimes. Currently the preferred solution to this epidemic is to impose longer and longer lengths of incarceration for every incurred infraction. Methods: A descriptive correlational design will be used for this research study to evaluate the effectiveness of drug court compared to incarceration. The participants will be chosen by a random sampling of 100 residents of the Hampton Roads area of Virginia--50 …

The Effect Of An Interprofessional Registered Nurse-Physical Therapist Team On Reducing Prescribed Opioid Dependence In Patients With Chronic Lower Back Pain, Amber Chesney, Stephanie Jan, Amanda Pedrazoli, Brandon Simmons, Kaylene Woods, Nicole Yeats

OUR Journal: ODU Undergraduate Research Journal

Long-term prescribed opioid use for chronic pain is shown to reduce recovery potential and increase risk for dependence, which is contributing to the nationwide opioid crisis. There is a need for an innovative, multidisciplinary approach to address prescription opioid dependence. We propose implementation of a community-based interprofessional registered nurse-physical therapist team (IRNPTT) focused on reduction of opioid dependence in adult patients with chronic lower back pain.

The Effect Of Clinician Competence And Religiosity On The Trainee Clinician’S Ability To Identify Problematic Sexual Behavior, Cody Butcher

All Graduate Theses, Dissertations, and Other Capstone Projects

Models in psychology do not consider the concept of sex addiction the same way as other substance or behavior addictions. For example, sex addiction, which is not a DSM-5 disorder, is often assigned as a label to clients based off of high frequency of sexual behavior. Despite sex addiction not being a diagnosable disorder, sex addiction therapists are conducting treatment with people who identify as sex addicts. Due to this lack of a definition, previous research has found that clinicians may identify sex addiction in clients based on their own preconceived worldviews of what types of sexual behaviors or frequencies …

Protective Behavioral Strategies As A Context-Specific Mediator: A Multilevel Examination Of Within- And Between-Person Associations Of Daily Drinking, Abby L. Braitman, Ashley N. Linden-Carmichael, James M. Henson

Psychology Faculty Publications

Research indicates that a drinker’s environmental and social context can be differentially associated with drinking outcomes. Further, although many researchers have identified that more frequent use of protective behavioral strategies (PBS) is associated with lower alcohol consumption and negative consequences, scant research has examined how one’s drinking context may promote or hinder PBS use. The present study examined how the context of drinking each day (i.e., where and with whom) is associated with level of consumption and reported alcohol-related problems among n = 284 college drinkers (69.0% female) directly, as well as indirectly through the use of PBS. Two different …

Drinking To Cope With Depressive Symptoms And Ruminative Thinking: A Multiple Mediation Model Among College Students, Adrian J. Bravo, Matthew R. Pearson, James M. Henson

Psychology Faculty Publications

Background: Understanding the potential psychosocial mechanisms that explain (i.e., mediate) the associations between depressive symptoms and alcohol-related problems can improve interventions targeting college students.

Objectives: The current research examined four distinct facets of rumination (e.g., problem-focused thoughts, counterfactual thinking, repetitive thoughts, and anticipatory thoughts) and drinking to cope motives as potential explanatory mechanisms by which depressive symptoms are associated with increased alcohol-related problems.

Method: Participants were undergraduate students from a large, southeastern university in the United States that consumed at least one drink per typical week in the previous month (n = 403). The majority of participants were female ( …

Developmental Toxicity Of Nicotine: A Transdisciplinary Synthesis And Implications For Emerging Tobacco Products, Lucinda J. Enland, Kjersti Aagaard, Michele Bloch, Kevin Conway, Kelly Cosgrove, Rachel Grana, Thomas J. Gould, Dorothy Hatsukami, Frances Jensen, Denise Kandel, Bruce Lanphear, Frances Leslie, James R. Pauly, Jenae Neiderhiser, Mark Rubinstein, Theodore A. Slotkin, Eliot Spindel, Laura Stroud, Lauren Wakschlag

Pharmaceutical Sciences Faculty Publications

While the health risks associated with adult cigarette smoking have been well described, effects of nicotine exposure during periods of developmental vulnerability are often overlooked. Using MEDLINE and PubMed literature searches, books, reports and expert opinion, a transdisciplinary group of scientists reviewed human and animal research on the health effects of exposure to nicotine during pregnancy and adolescence. A synthesis of this research supports that nicotine contributes critically to adverse effects of gestational tobacco exposure, including reduced pulmonary function, auditory processing defects, impaired infant cardiorespiratory function, and may contribute to cognitive and behavioral deficits in later life. Nicotine exposure during …

Associations Of Suicidal Ideation With Opioid/Prescription Drug Use, Violence, Food Insecurity, And Community Factors Among New Hampshire High School Students, Emily R. Carbonara, Semra Aytur

Honors Theses and Capstones

Purpose: Suicide is the second leading cause of death for New Hampshire (NH) youth. Evidence-based public health emphasizes the use of data for translating research into practice/policy. We utilized data from the Youth Risk Behavior Survey (YRBS) to support community-academic partnerships and inform suicide prevention interventions. Methods: Data from the 2011 NH YRBS, a cross-sectional survey of 9th-12th grade students, were analyzed. Gender-stratified, adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were estimated using logistic regression models (SAS 9.4, ProcSuveylogistic) to evaluate associations between suicidal ideation (seriously considering attempting suicide within the past 12 months), violence (e.g., physical bullying, …

Emerging Adults And Recovery Capital: Barriers And Facilitators To Recovery, Alex Elswick

Theses and Dissertations--Family Sciences

Substance use disorders are chronic brain disorders and must therefore be treated on an ongoing basis. Accordingly, the concept of recovery capital has been developed to account for the internal and external resources that an individual can mobilize in order to recover from a substance use disorder. However, the concept has scarcely been applied to emerging adults. Although they are at twice the risk of developing a substance use disorder relative to their adult or adolescent counterparts, emerging adults in addiction and recovery are understudied. This phenomenological study aims to explore and describe the experience of emerging adults in recovery …

Assessment Of The Use Of Overdose Education And Naloxone Distribution By Maine Buprenorphine/Naloxone Prescribers, Stephen Kirsch

Muskie School Capstones and Dissertations

Background: Overdose deaths, specifically related to opioids, have been identified as a public health problem both nationally and in the state of Maine. Overdose Education and Naloxone Distribution (OEND) is an innovative model of patient education that has been shown to be effective in increasing knowledge of overdose risk and has the potential to help reduce opiate related overdose deaths.

Methods: A 28-item web-based survey examining clinician attitudes, OEND practices and characteristics was distributed to 196 Maine based physicians with a Drug Enforcement Agency waiver to prescribe burprenorphine/naloxone. Facilitators and barriers to the provision of OEND were also assessed. Surveys …

Urine Cotinine In Children And Parental Behavior Modification: A Pilot Study, Teresa Lachance

Muskie School Capstones and Dissertations

“Urine Cotinine in Children and Parental Behavior Modification” was designed by Dr. Deirdre Burns, a pediatrician at the Barbara Bush Children’s Hospital (BBCH). It was implemented as a pilot study to determine whether urine cotinine testing in children who are admitted to the hospital for respiratory illness and tracking parental smoking behaviors over time was feasible. Parents were given a brief survey to assess their current smoking behaviors and to understand their readiness to quit smoking. They received smoking cessation materials provided by the Breathe Easy Coalition of Maine. These materials outline information about second-hand and third-hand smoke, and encourage …

Intramuscular Route Of Administration Increases Potency In Eliciting Cocaine-Induced Behavioral Sensitization, Beth Ann Rice, Raza Tariq, Chana K. Akins

Psychology Faculty Publications

Background: Cocaine is the number one abused psychostimulant drug that reaches addiction criterion in the US. In animals, repeated administration of cocaine results in behavioral sensitization which is thought to represent adaptations in the mesolimbic dopamine neural circuitry, the reward pathway. Cocaine-induced behavioral sensitization is evident in rodents and quail when cocaine is administered intraperitoneally (IP).

Objective: The purpose of the current study was to investigate dose-dependent and temporal effects of acute and chronic intramuscular (IM) administration of cocaine in male quail.

Method: After habituation to the test chambers, male quail received an IM injection of saline, 3 or 10 …

Childhood Drinking And Depressive Symptom Level Predict Harmful Personality Change, Elizabeth N. Riley, Gregory T. Smith

Psychology Faculty Publications

Personality traits in children predict numerous life outcomes. Although traits are generally stable, if there is personality change in youth, it could affect subsequent behavior in important ways. We found that the trait of urgency, the tendency to act impulsively when highly emotional, increases for some youth in early adolescence. This increase can be predicted from the behavior of young children: alcohol consumption and depressive symptom level in elementary school children (fifth grade) predicted increases in urgency 18 months later. Urgency, in turn, predicted increases in a wide range of maladaptive behaviors another 30 months later, at the end of …

Cellular And Molecular Mechanisms Underlying Alcohol-Induced Aggressiveness Of Breast Cancer, Yongchao Wang, Mei Xu, Zun-Ji Ke, Jia Luo

Pharmacology and Nutritional Sciences Faculty Publications

Breast cancer is a leading cause of morbidity and mortality in women. Both Epidemiological and experimental studies indicate a positive correlation between alcohol consumption and the risk of breast cancer. While alcohol exposure may promote the carcinogenesis or onset of breast cancer, it may as well enhance the progression and aggressiveness of existing mammary tumors. Recent progress in this line of research suggests that alcohol exposure is associated with invasive breast cancer and promotes the growth and metastasis of mammary tumors. There are multiple potential mechanisms involved in alcohol-stimulated progression and aggressiveness of breast cancer. Alcohol may increase the mobility …

Is Yoga Effective In Preventing Nicotine Cravings During Smoking Cessation In Adults?, George F. Donohue

PCOM Physician Assistant Studies Student Scholarship

No abstract

The Relationship Between Alcohol Use And Familial And Social Influence In College Nursing Students, Darren C. Crooks, Kathleen A. Gillota

Williams Honors College, Honors Research Projects

College students are a population with a high prevalence of risky consumption of alcohol and nursing students, specifically, are no exception. Yet few studies have been done on the use of alcohol in the student-nurse population. Since nursing education and practice are highly stressful, unhealthy coping strategies, such as risky alcohol consumption, are sadly common and seriously detrimental.

This paper explores the self-reported consumption of alcohol in undergraduate nursing students as related to peer, familial, and social influences. Based on the Biopsychosocial Model, many different factors contribute to alcohol use. Using anonymous online survey methodology and convenience sampling, data about …

A Pilot Study Of Online Feedback For Adult Drinkers 50 And Older: Feasibility, Efficacy, And Preferences For Intervention, Alexis Kuerbis, Lisa Hail, Alison A. Moore, Frederick Muench

Publications and Research

Normative (NF) and personalized feedback (PF) are moderately effective brief interventions for at-risk drinking middle-aged and older adults. This study tested the feasibility of online feedback for drinkers 50 and older. This study’s aims were to identify whether there is differential effectiveness of PF over NF in prompting drinkers 50 years old and older to plan for change and to determine potential preferences for intervention among adult drinkers 50 and older with practical knowledge about computers. Method—Using Amazon’s Mechanical Turk, 138 male and female drinkers aged 50 to 75+ were recruited to complete an online survey that asked about their: …