Substance Abuse and Addiction Commons^™

Check Your Data Before You Wreck Your Model: The Impact Of Careless Responding On Substance Use Data Quality, Abby L. Braitman, Anna M. Petrey, Jennifer L. Shipley, Rachel Ayala Guzman, Emily Renzoni, Alison Looby, Adrian J. Bravo

Psychology Faculty Publications

Background: The accuracy of survey responses is a concern in research data quality, especially in college student samples. However, examination of the impact of removing participants from analyses who respond inaccurately or carelessly is warranted given the potential for loss of information or sample diversity. This study aimed to understand if careless responding varies across a number of demographic indices, substance use behaviors, and the timing of survey completion.

Method: College students (N = 5809; 70.7% female; 75.7% White, non-Hispanic) enrolled in psychology classes from six universities completed an online survey assessing a variety of demographic and substance use-related information, …

Psychometric Evaluation Of A Novel Measure Of Trauma-Related Cannabis Use To Cope, Sage E. Hawn, Terrell A. Hicks, Christopher Latourrette, Anita Thomas, Daniela Chaname, Sarah Ehlke, Abigail Powers Lott

Psychology Faculty Publications

Background: Posttraumatic stress disorder (PTSD) and cannabis use disorder (CUD) are commonly comorbid and are associated with many negative public health outcomes. One plausible explanation for this comorbidity comes from a self-medication framework, which suggests people use cannabis to cope with PTSD symptoms. Despite theoretical and empirical evidence for PTSD-related cannabis use to cope, no measure of this construct exists.

Objective: We sought to address this gap by developing and validating a novel measure of PTSD-specific cannabis self-medication, which we have termed the Trauma-Related Cannabis Use to Cope (TRCU) questionnaire.

Method: The psychometric properties of the TRCU and how it …

Identifying Salient Social, Environmental, And Situational Contexts Of College Drinking: Impacts Across Drinking Outcomes, Abby L. Braitman, Jennifer L. Shipley, Megan Strowger, Emily S. Renzoni

Psychology Faculty Publications

Background and Objectives: Drinking context, such as where, why, and under what social conditions drinking occurs, is consistently associated with daily variability in alcohol use. However, ecological momentary assessment (EMA) requires very brief measurement, not allowing for as many contextual assessments as researchers may like. The current investigation examined common contextual predictors and their associations with different alcohol outcomes.

Methods: A sample of N=528 college drinkers completed three surveys about their most recent drinking episode. This included contextual predictors (location, social context, who was present, alcohol offers, and drinking motives), as well as typical drinking outcomes (number of drinks, estimated …

Understanding The "Paradox" In Black-White Alcohol Outcomes: Examining High-Effort Coping And Health Behaviors With A Focus On Black Populations And College Students, Rachel Ayala Guzman, Abby L. Braitman

Psychology Faculty Publications

Despite experiencing more physical health disadvantages and psychosocial stressors, Black Americans consistently report better mental health outcomes compared to White Americans—a phenomenon commonly referred to as the Black-White health paradox. Alcohol research has identified another racial paradox suggesting Black Americans are at greater risk for alcohol-related problems despite drinking less than White Americans, which is known as the Black-White alcohol paradox. While both paradoxes are well-documented, few studies have examined their potential overlap or how insights from one might inform understanding of the other. Although the alcohol paradox is usually examined among older adults, it may be important to consider …

Inpatient Utilization Among Medicaid Members With Substance Use And Serious Mental Illness In Oregon, Megan Holtorf

Articles, Abstracts, and Reports

No abstract provided.

Prevention Of Substance Related Deaths Through Mental Health Counseling, Lindsey Tout, Camille Zonfa

Scholarship in Medicine - All Papers

Background: Substance abuse, particularly alcohol and drug use, remains a critical public safety issue in Ohio. Those suffering with abuse disorders are likely to often have accompanying mental health disorders, however, there lies a significant gap in treatment.
Objective: This study examines trends in alcohol-related driving deaths, drug overdose deaths, excessive drinking, and mental health provider availability from 2016 to 2023 in rural and urban counties of Ohio.
Methods: Data collected from the public source, County Health Rankings and Roadmaps, was analyzed using statistical methods to assess changes between 2016 to 2023 for the 88 counties of Ohio. Urban versus …

An Analysis Of Alcohol, Mental Health, And Suicide, Motassem Bayyoud, Megan Galluch

Scholarship in Medicine - All Papers

Suicide rates in Montana, Iowa, Ohio, and New Jersey vary strongly and encompass the wide range seen across all fifty states in America. Previous research has told us that there is a significant relationship between Alcohol Use Disorder and the ideation, attempt, and completion of suicide. Additionally, most people who are victims of suicide suffer from mental disorders. People use alcohol to cope with mental health and alcohol leads to deteriorating and adverse outcomes in a person’s life. To attempt to better understand the relationship between these variables and why suicide rates differ so widely, an analysis of binge drinking, …

The Opioid Crisis: Analyzing Access To Resources, Mental Health And The Influence On Overdose Deaths In Urban And Rural Communities, Katharina Johnson, Maggie Obourn

Scholarship in Medicine - All Papers

Background: Opioid use contributes significantly to deaths throughout the United States. Opioid overdose deaths have increased in recent years and the opioid crisis has far reaching effects on many communities. There are several factors that contribute to opioid overuse and death, including access to resources and social factors.
Objective: In this study we aimed to assess how social factors affect overdoses by examining the differences between rural and urban communities over time.
Methods: We utilized data from County Health Rankings and conducted a retrospective review of data from 2016 and 2023 to compare several factors that we hypothesized affected opioid …

Peer Supporter Perspectives On The Roots Of Addiction:A Qualitative Study, Elise Hubert, Sydney Silverstein

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The aim of this study is to qualitatively evaluate the origins of addiction through the perspective of individuals with lived experience.

Defederalizing Opioid Addiction Care, Matthew B. Lawrence

Faculty Articles

Lack of access to evidence-based care for drug addiction is an urgent problem amid a decades-long overdose crisis that kills tens of thousands of Americans a year. Opioid addiction is the primary driver of overdoses today, and medicines exist to treat such addiction that can dramatically improve quality of life while reducing the risk of deadly overdose by more than half. Yet fewer than one in four of the nine million Americans who need such evidence-based medical care for their addiction receive it. Chief among barriers to access are restrictive and burdensome federal requirements limiting the use of narcotic medications …

Anxiolytic Intervention: Modulation Of Cell Types Due To Nicotine Withdrawal, Taylor Elder

Theses and Dissertations--Pharmacy

Nicotine use disorder (NUD) remains a leading cause of preventable disease, yet the neurobiological mechanisms underlying nicotine withdrawal are incompletely understood. Emerging evidence implicates neuroimmune signaling and astrocytic regulation of glutamate in shaping the withdrawal-associated affective phenotype. This dissertation investigated these processes using multiple nicotine administration paradigms including osmotic minipump implant, cigarette smoke exposure, and nicotine vapor inhalation to model diverse routes of human nicotine intake.

Chapter 2 examines the effects of these three modes of administration on neuroinflammation and validation of nicotine delivery. Nicotine exposure was confirmed through receptor [³H]Epibatidine nAChR binding assay and serum cotinine measurements. …

Investigating The Role Of Dynamic Signaling Of Nrg3-Erbb4 In The Prefrontal Cortex In Mediating Nicotine Withdrawal Phenotypes, Emily Prantzalos

Theses and Dissertations--Pharmacy

While several pharmacotherapies are currently available for nicotine use disorder (NUD), smoking cessation success rates remain below 10% each year. The molecular mechanisms underlying failed quit attempts continue to represent a critical gap in our knowledge. However, recent advances in understanding the genetic contributions to nicotine dependence offer a promising avenue for developing more effective cessation therapies. Prior research has identified genetic variation in Neuregulin 3 (Nrg3) and its cognate receptor ErbB4 as potential contributors to affective nicotine withdrawal (WD) phenotypes and cessation outcomes. Therefore, this dissertation aims to systematically investigate the region-specific, functional role of the Neuregulin Signaling Pathway …

“What We Say Matters”: Reducing Drug Use Stigmatization By Healthcare Professionals Through A Narrative-Based Awareness Campaign, Adam M. Traugott

DNP Projects

Background: Stigma towards substance use has been identified as a contributor to poor care and health outcomes amongst people who use drugs (PWUD), a vulnerable population. Healthcare worker stigma negatively affects the outcomes of individual patients and may have greater public health implications. Methods of addressing drug-use stigma have previously been implemented in a variety of clinical settings. Presenting the lived experience of PWUD to healthcare workers via emotionally compelling narratives has been found to be an effective means of stigma reduction.

Purpose: This study utilized two psychometrically validated tools to measure (1) the baseline prevalence of drug use stigma …

The Impact Of Socioeconomic Status On Substance Use Amongst The Hispanic Maternal Population, Emily C. Olivo

Honors Undergraduate Theses

Aim: To explore and synthesize existing research that focuses on the relationship between socioeconomic status and the use of substances amongst the maternal Hispanic population. By examining research and these factors, interventions can be identified to lower reported substance use rates amongst Hispanic mothers of childbearing ages.

Background: Minorities such as Hispanic women deal with a myriad of struggles, especially during motherhood. Socioeconomic status and substance use can contribute to a large part of the struggles faced by this population. Hispanic and Latina will be used interchangeably throughout this review of literature.

Method: A comprehensive electronic review of 3 databases …

Organization And Activation Of Caffeine Expectancies, Catherine S. Forsyth

Honors Undergraduate Theses

Caffeine is the most consumed and widely used psychoactive substance in the world. Whether someone uses caffeine or not, expectations about use can be influential to some degree. Expectancies exist everywhere and are extremely influential in all aspects of life. Regarding drug use, expectancies can affect behavior, outcomes, and one’s experience with the drug. Caffeine is no exception, caffeine expectancies have been seen to play a role in several actions such as the development, maintenance, and reinforcement of caffeine use. This study examined latent use profiles of caffeine and relationships between the profiles and the activation of caffeine expectancies. Multidimensional …

Confidentiality In Addiction Treatment: Navigating 42 Cfr Part 2 Within Human Services, Chaniece Winfield, Jessica Huffman

Counseling & Human Services Faculty Publications

Recent federal legislation, including the Mental Health Parity and Addiction Equity Act (MHPAE) and the Comprehensive Addiction and Recovery Act (CARA), has placed greater emphasis on quality integrated health care, with a focus on access, treatment options, and evidence-based practices. Changes to Federal 42 CFR privacy protections also impact individuals seeking substance use disorder treatment, either as a primary diagnosis or comorbidity. Human service professionals, as generalists in the behavioral health field, provide vital treatment, recovery, and prevention services for individuals with substance use and addictive disorders. This paper explores the implications of these legislative changes, particularly regarding privacy protections …

Navigating Recovery: Insights From Distance Learning Human Services Students' Abstinence Experience, Chaniece Winfield, Jill Kivikoski, Catalina Kraft

Counseling & Human Services Faculty Publications

With the rise in overdose and problematic drug use in the United States, it is crucial to develop competent human service practitioners in addiction treatment and recovery settings. This qualitative study explores the virtual abstinence experience of distance learning human services students, using Mezirow’s transformative learning theory to examine how a 21-day experiential abstinence prompts critical reflection and perspective transformation. The study investigates the socio-emotional and physiological factors influencing participants' progress toward sobriety, including cravings, withdrawal, isolation, and relapse triggers. Findings highlight how participants' critical reflection leads to a deeper understanding of addiction and recovery, as well as an enhanced …

Examining The Addictive Qualities Of Smartphone Usage, Daniel J. Pasquini

Antioch University Dissertations & Theses

Individuals in today’s society, both nationally and globally, have become exceedingly reliant on their smartphones, i.e., cellular devices with the ability to perform many tasks similar to a traditional computer, for both recreational and productivity purposes. As smartphones become increasingly accessible and affordable for the general population, smartphone usage will continue to grow exponentially. As a result, a comprehensive investigation into the possible addictive properties of smartphone usage is warranted. The purpose of this study is to examine and highlight any possible addictive qualities of excessive smartphone usage. The research methodology that will be implemented within the study will be …

Residual Next-Day Effects Of Alprazolam On Psychomotor Performance And Simulated Driving In Healthy Normal Adults, Stevie C. Roszkowski, Shanna Babalonis, Marion A. Coe, Paul Nuzzo, Michelle R. Lofwall, Laura C. Fanucchi, Sharon L. Walsh

Center on Drug and Alcohol Research Faculty Publications

The prevalence of drugged driving has increased in the United States. Some drugged driving may be unintentional as prescription medications used as sleeping aids, like zolpidem, cause impairment after the predicted duration of therapeutic action has elapsed. The aim of this study was to determine if nighttime administration of alprazolam, a drug commonly prescribed off-label as a sleeping aid, impacts driving performance the following day. Participants were healthy adults (n = 15) who completed a double-blind, double-dummy, within-subjects inpatient study examining the effects of nighttime administration of alprazolam (0.5, 1, and 2 mg), zolpidem (10 mg), and placebo on driving …

Barriers To And Facilitators Of Buprenorphine Dispensing For Opioid Use Disorder: Evidence From Focus Groups In Appalachian Kentucky, Douglas R. Oyler, Dustin K. Miracle, Hannah Hesener, Laura Stinson, Monica Roberts, Adrienne Matson, Patricia R. Freeman

Pharmacy Practice and Science Faculty Publications

Background: As efforts to increase buprenorphine prescribing continue to intensify, pharmacy dispensing plays an important role in access to essential medications for opioid use disorder. Existing survey research suggests stigma and regulatory concerns are barriers to pharmacists dispensing buprenorphine, but facilitators are less clear, as are in-depth perceptions of pharmacists regarding buprenorphine.

Objective: To assess barriers and facilitators to buprenorphine dispensing in Appalachian Kentucky using a series of focus groups with pharmacy employees.

Methods: Between September and October 2023, 5 structured focus groups were conducted with a total of 19 pharmacists and pharmacy technicians across a mixture of high- and …