Substance Abuse and Addiction Commons^™

Delta-8 Tetrahydrocannabinol Policy And Related Health Impact Among College-Aged Individuals In South Carolina: A Scoping Review, Emily K. Luoma

Senior Theses

After the 2018 Farm Bill passed, loopholes were quickly found that led to the popularization of delta-8 THC, a derivative of delta-9 THC, more commonly known as marijuana. Use of this substance became particularly high in states that criminalized marijuana, such as South Carolina. This scoping review aimed to assess South Carolina’s current delta-8 policies in the context of health-related impacts among college-aged students. Comprehensively analyzing the results of relevant studies, it was determined that there are three commonly observed threats to public health that are direct outcomes of existing policies: 1) a lack of quality control standards; 2) misleading …

Hubungan Dukungan Sosial Rekan Kerja Dengan Stres Kerja (Studi Pada Pekerja Di Pt X), Aisyah Permatasari

Jurnal Ilmu Kesejahteraan Sosial

Workers are vulnerable to work-related stress due to job demands, time constraints, and limited leisure time, leading to psychological issues such as anxiety related to their work. In the context of social welfare studies, job stress affects overall workers’ well-being and disrupts their social functioning in the workplace. Social support from coworkers is potentially reduce stress in workplace, which is crucial for creating organizational well-being. It also helps workers improve job engagement, cope with fatigue, and manage stress. This study examined the relationship between social support from coworkers and job stress among 90 employees …

Caring Across Borders: Demographic Shifts And Migrant Care In Asean-Korea Dynamics, Saqib Fardan Ahmada, Wahid Nur Kartiko

Jurnal Ilmu Kesejahteraan Sosial

This article aims to examine the migration policies and migrant care in the context of relations between ASEAN Member States (AMS) and Korea. As Korea is dealing with an aging population, an increase in female labour force participation, and an ultra low fertility rate, caregiving, especially for the elderly, has become a pivotal issue. Besides, the traditional nuclear family structure, which has historically served as the primary caregiver for the elderly, is also losing its prominence. In such demographic shift, migrant care workers from AMS are filling the demand for caregiving in Korea, leading to a cross-border international migration from …

Unveiling The Stigma: Doctor Mental Health And Intervention Strategies, Joseph Heirigs

Honors Program: Senior Projects (Public)

Background

The mental health of physicians is a pressing issue that has received increasing attention in recent years. The alarmingly high suicide rates for physicians underscores the critical need to address the mental health challenges that doctors face. Physicians are exposed to stressors that are unique to their profession, including high-stakes decision making, long work hours, traumatic patient situations, and the emotional toll of patient care. These challenges contribute to high rates of anxiety, depression, burnout, and other mental health issues. However, despite these factors, physicians are often reluctant to seek mental health treatment due to fears of professional repercussions, …

Effect Of Chronic Alcohol Feeding Using The Lieber-Decarli Diet On Alzheimer’S Disease Pathology In Tg2576 Mice, Devaraj V. Chandrashekar, Nataraj Jagadeesan, Tamara Abdullah, Rudy Chang, Ross A. Steinberg, Frankey Sanchez, Elias Khal, Joshua Yang, David H. Cribbs, Derick Han, Rachita K. Sumbria

Pharmacy Faculty Articles and Research

Background: Chronic alcohol drinking is a modifiable risk factor for Alzheimer’s disease (AD), but underlying mechanisms remain poorly understood. Most studies of alcohol feeding to AD mice have utilized young mice and delivered alcohol in drinking water without controlling nutritional intake.

Objective: To study the impact of Lieber-DeCarli (LDC) liquid alcohol diet, which balances nutritional intake, on AD pathology of aged Tg2576 and wild-type (WT) mice, which is unexplored.

Methods: 13-month-old male and female Tg2576 or WT mice were fed LDC diet (5% ethanol or control) for six weeks (n = 11-13/group). Exploration (open-field test) and spatial reference memory …

Shuffle, Dereck Daschke

Journal of Religion & Film

This is a film review of Shuffle (2025), directed by Benjamin Flaherty.

Hospital Re-Admission, Length Of Stay, And Chief Complaints Of Patients Experiencing Housing Instability, Andrew S. Leavitt, Jainaha K. Srikumar, Rizwan M. Siddiqui, Luke R. Siedhoff, Jennifer Liu, Jenenne Geske

EMET Projects

No abstract provided.

Hospital Admissions Of Patients Experiencing Housing Instability, Rizwan M. Siddiqui, Jainaha K. Srikumar, Andrew S. Leavitt, Luke R. Siedhoff, Jenenne Geske, Jennifer Liu

EMET Projects

No abstract provided.

Fact Sheet: Methamphetamine, Aaron Hunt, Gabriela Murza, Jenna Hawks, Alyssa Ferrin

All Current Publications

Methamphetamine, or meth, is a powerful stimulant that speeds up the central nervous system, causing increases in heart rate, blood pressure, and how fast the body uses energy. This fact sheet explains how meth is habit-forming and addictive and what it does to your body. It also explains overamping and responding to such an emergency.

Fact Sheet: Ketamine, Aaron Hunt, Gabriela Murza, Jenna Hawks, Alyssa Ferrin

All Current Publications

This fact sheet discusses ketamine, which has pain-relieving properties and has gained recent attention for its antidepressant effects. However, as a Schedule III substance, it has a risk of strong psychological and physical dependence. Recreational use can lead to short- and long-term effects on health and risk of overdose and death.

Fact Sheet: Fentanyl, Aaron Hunt, Gabriela Murza, Amy May, Jenna Hawks, Alyssa Ferrin

All Current Publications

This fact sheet provides essential information on fentanyl, a potent synthetic opioid increasingly found in illegal street drugs, posing significant overdose risks. It highlights how opioids affect the body, the dangers of fentanyl, and the importance of harm-reduction strategies, such as fentanyl test strips, naloxone access, and safe syringe disposal. Information on signs and symptoms and how to respond to an overdose are also included.

Contraceptive Hormone Influences On The Role Of Primary Reinforcement And Reinforcer-Enhancement In Nicotine Self-Administration, Kathleen Robin Mcnealy

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Hormonal contraceptives contain a synthetic estrogen (e.g., ethinyl estradiol/EE) and/or a synthetic progestin (e.g., levonorgestrel/LEVO) and can exacerbate nicotine intake. However, whether altered intake reflects changes in nicotine reinforcement or enhancement by nicotine of co-occurring reinforcers is unknown. This reinforcer-enhancement effect is evidenced in rats when nicotine self-administration is increased by the presence of a visual stimulus (VS) reinforcer. This dissertation examined the effects of EE and LEVO on nicotine reinforcement and reinforcer-enhancement in ovary-intact female Sprague-Dawley rats. Rats were implanted with a jugular catheter and assigned to receive daily injections of EE (Vehicle, 0.125 [Low], or 0.18 [High] μg/day; …

Extended-Release Buprenorphine Could Overcome Barriers To Medical Treatment Of Opioid Use Disorder In At-Risk Populations, Scott A. Davis, Genevieve Verrastro, E Blake Fagan

HCA Healthcare Journal of Medicine

This article discusses how monthly extended-release buprenorphine can be used to improve the treatment of opioid use disorder (OUD). In particular, the use of monthly extended-release buprenorphine holds promise for patients who have recently been released from jail or prison and are battling OUD, those who are unstable and continue to use opioids illicitly, patients who are experiencing homelessness while also struggling with OUD, and those who are stable and want to be weaned off buprenorphine.

Pornography, Problematic Use And Academic Outcomes In College Students: A Cross-Sectional Analysis, Promise Tewogbola, Victoria Bodunde, Deborah Odaudu

Journal of Graduate Education Research

Background: The prevalence of pornography consumption among college students has raised concerns about its potential impact on academic performance. This study aims to examine the relationships between pornography use, academic outcomes, and problematic pornography use among university students.

Methods: A cross-sectional study was conducted with 739 students from a Midwestern U.S. state university. Participants completed an online survey assessing demographics, grade point average (GPA), pornography consumption frequency, Academic Success Inventory (ASI) scores, and Problematic Pornography Use (PPU) scale scores. Logistic and linear regression analyses were used to examine associations between variables.

Results: Pornography consumers had 41% lower odds of …

In-Silico Modeling And Characterization Of Kcc2 Protein Interaction With A Small Molecule Direct Agonist Identifies Potential Binding Sites For Modulating Behaviors Associated With Substances Of Abuse, William Hai Dang Ho, Alfred Amendolara, Kenyon Mitchell, Jaden Miner, Ruth Northcott, Braxton Bingham, Andrew J. Payne

Annual Research Symposium

Purpose

KCC2 is a potassium-chloride cotransporter that plays a critical role in neuronal function by regulating GABAergic signaling via chloride gradients. Maintaining this concentration gradient is crucial for balancing excitation and inhibition in the brain. While KCC2 dysregulation has been implicated in epilepsy and seizures, recent studies suggest that KCC2 inhibition results in phenotypes mirroring those seen in chronic opioid dependence. As such, increasing evidence support KCC2 being a potential therapeutic target for modulating behaviors associated with substances of abuse. Currently, only a few direct small molecule agonists against KCC2 have been reported, and no definitive active site on the …

How Do Gender And Marital Status Impact High-Risk Polysubstance Use?, Kira England, Alexander Chapman

Population Health Research Brief Series

Drug overdose deaths in the United States increasingly include the use of multiple drugs, known as polysubstance use. These include opioids, cocaine, methamphetamine, tranquilizers, and sedatives. Polysubstance use is considered high risk because it can cause dangerous synergistic effects and result in the ingestion of higher amounts of drugs. This brief summarizes findings from a study that used data from the National Survey on Drug Use and Health on U.S. adults from 2002 through 2019 to examine gender and marital status differences in high-risk polysubstance use among U.S. adults ages 18 and older. The authors find that polysubstance use is …

The Development Of Teacher Identity In Counselor Education Doctoral Students, Wes Allen, Joel F. Diambra, Rebecca Gaylor

Journal of Counselor Preparation and Supervision

Abstract

Counselor educators (CE) prepare counselor education doctoral students (CEDS) to work as counselors, scholars, leaders, supervisors, and teachers. While we have a firm understanding of how CEDS develop in general (Limberg et al., 2013; Moss et al., 2014), there is little known about how they develop specifically as teachers. The goal of this research study was to gain insight into how teacher identity develops for CEDS. We interviewed 10 participants using transcendental phenomenology methodology to gain insight into their teaching preparation experiences and identities as teachers. We identified three primary themes from the data: (1) Connection, (2) Confidence, or …

Investigating The Impact Of Tirzepatide Treatment On Alcohol And Cigarette Consumption, Yvannia Gray, Benjamin Latey, Hayden Mcaffee, Karissa Mccown, Seth Maki, Victoria Nguyen, Andrew Payne

Annual Research Symposium

No abstract provided.

Exploring The Therapeutic Potential Of Resveratrol In Substance Use Disorders: A Systematic Review Of Its Effects On Kcc2 Expression, Lauren R. Nelson, Ashlyn Hughes, Jory Winward, Natalie Phanco, Andrew Payne Phd

Annual Research Symposium

No abstract provided.

Investigating The Effects Of Resveratrol On Opioid-Induced Hyperalgesia, Bryana Cox, Thien Do, Ashlyn Hughes, Zane Kingsbury, Keara Leroy, Andrew J. Payne

Annual Research Symposium

Opioid-induced hyperalgesia (OIH) is an adverse effect of chronic opioid therapy, characterized by increased sensitivity to pain. This study will seek to determine if using resveratrol supplementation as an indirect enhancer to increase the expression of the KCC2 membrane transporter can alleviate the symptoms of OIH in human subjects.