Mental and Social Health Commons^™

Nexmif Pathogenic Variants In Individuals Of Korean, Vietnamese, And Mexican Descent, Elizabeth Langley, Laura S Farach, Mary K Koenig, Hope Northrup, David F Rodriguez-Buritica, Kate Mowrey

Faculty, Staff and Student Publications

NEXMIF pathogenic variants have been known to produce a wide spectrum of X-linked intellectual disability (ID) in both males and females. Thus far, few individuals from diverse populations have been described with NEXMIF-related disorders. Herein, we report three individuals with NEXMIF pathogenic variants, the first two are the only males of Korean and Vietnamese descent described with this disorder to our knowledge. The last patient is a Hispanic female who harbors the same pathogenic variant as a previously described Caucasian individual, but with differing clinical presentation. These patients present with many classic symptoms of NEXMIF-related disorders including ID, epilepsy, developmental …

Are Thyrotropin-Releasing Hormone (Trh) And Analog Taltirelin Viable Reversal Agents Of Opioid-Induced Respiratory Depression?, Marieke Hyke Algera, Joseph F Cotten, Monique Van Velzen, Marieke Niesters, Martijn Boon, Daniel S Shoham, Kaye E Dandrea, Rutger Van Der Schrier, Albert Dahan

Faculty, Staff and Student Publications

Opioid-induced respiratory depression (OIRD) is a potentially life-threatening complication of opioid consumption. Apart from naloxone, an opioid antagonist that has various disadvantages, a possible reversal strategy is treatment of OIRD with the hypothalamic hormone and neuromodulator thyrotropin-releasing hormone (TRH). In this review, we performed a search in electronic databases and retrieved 52 papers on the effect of TRH and TRH-analogs on respiration and their efficacy in the reversal of OIRD in awake and anesthetized mammals, including humans. Animal studies show that TRH and its analog taltirelin stimulate breathing via an effect at the preBötzinger complex, an important respiratory rhythm generator …

Factors Associated With The Nutritional Status Of Infants And Young Children From Rural Honduras, Ana M. Palacios, Mario Keko, Aishat Adewoye, Haresh Rochani, Asli Aslan, Dziyana Nazaruk, Ana Gisela Ramos, Weston L. Oliver, Laura Manship

Health Policy & Community Health: Faculty Publications

Objectives

Malnutrition is a major public health problem in children. Undernutrition and excessive weight at young ages are associated with life-long consequences. The main objective of this study was to characterize the sociodemographic and food insecurity factors associated with the nutritional status of rural children ages 6 to 24 months living in 27 rural communities in Intibucá, Honduras.

Methods

This secondary analysis of baseline data included a total of 402 children ages 6 to 24 months who were recruited to participate in a cluster-non-randomized trial of a community-based nutrition intervention. Data were collected in January 2021 through a survey that …

Pathways For Healing: An Online Therapeutic Support Group Program, Lisa Yvette Salazar

Loma Linda University Electronic Theses, Dissertations & Projects

Pathways for Healing: An Online Therapeutic Support Group Program (OTSG) is for women, ages 18 to 65 years old, diagnosed with chronic pelvic floor dysfunction (PFD). The program focuses on women living in Texas rural communities with limited access to mental health providers. The aim for this study is to determine if an OTSG program, utilizing narrative therapy (NT) within a biopsychosocial-spiritual lens (BPS-S) will improve overall health-related quality of life (HRQOL). Support groups are provided in English and Spanish, over the course of 12 weeks, facilitated by a licensed marriage and family therapist (LMFT) and licensed pelvic floor physical …

Decolonizing Psychotherapy, Nicole D. Taylor

Loma Linda University Electronic Theses, Dissertations & Projects

This project aims to increase the use and inclusivity of mental health services within marginalized communities by providing education and training tools on the use and application of integrative mental health approaches. It is an offering of guidance, providing a culturally responsive framework for integrating yoga into psychotherapy. The manual aims to reduce systemic, colonialist, barriers to mental health services. This project is founded on the basis that mono-cultural foundations in traditional psychotherapeutic treatments negatively impact the attitudes and beliefs of service seekers, typically within excluded groups. Systems Theory and Critical Race Theory and Social Justice principles inform the application …

Soy Diferente: A Qualitative Study On The Perceptions Of Recovery Following Traumatic Brain Injury Among Spanish-Speaking Us Immigrants, Monique R Pappadis, Angelle M Sander, Margaret A Struchen, Diana M Kurtz

Faculty, Staff and Students Publications

PURPOSE: To explore the impact of traumatic brain injury (TBI) on the quality of life (QoL) and self-concept of Spanish-speaking U.S. Hispanic immigrants with TBI.

MATERIALS AND METHODS: A prospective, qualitative study conducted in a county level I trauma center and community. Semi-structured interviews on QoL and self-concept following TBI were conducted with 24 Spanish-speaking U.S. Hispanic immigrants with TBI living in the community at least 6 months following injury.

RESULTS: Perceived facilitators of QoL included faith, hopefulness in recovery, empathy for others, and support from others. Perceived barriers to QoL mentioned were symptoms/consequences of injury, employment/financial changes, loss of …

Longitudinal Patterns Of Suicidality Among Heroin Users In Johannesburg, South Africa: A Need For Suicide Screening And Intervention, Nirvana Morgan, Ellen-Ge Denton, Ugasvaree Subramaney, William Daniels, Tilman Steinert

Publications and Research

Objectives: The objective of the study was to longitudinally assess the outcomes and correlates of suicidal ideation and behavior (SIB) among heroin users who attended inpatient detoxification and psychosocial rehabilitation. SIB was assessed in 300 heroin users upon entry into inpatient detoxification (baseline) as well as 3-months (t1) (n = 252; 84%) and 9-months (t2) (n = 225; 75%) post treatment. Multivariable logistic regression was used to determine the demographic, clinical and treatment related factors that increased the risk for a high SIB score.

Results: From baseline to t1 there was a significant decrease in the proportion of …

Implementing Adverse Childhood Experience Screening In An Intensive Outpatient Mental Health Program, Bryan Amaro

Doctor of Nursing Practice Final Manuscripts

Adverse Childhood Experiences (ACES) are linked to damaging events which happen to people when we are young (0-18). ACEs are connected to a phenomenon known as the toxic stress response which can later become the root etiology for many mental health, substance abuse and chronic medical health complications our society faces. ACEs affect all populations and do not discriminate across socioeconomic, racial, ethnic, gender, or geographic lines. Roughly two thirds of Americans have experienced at least one ACE. This project seeks to perform ACE screening at an Intensive Outpatient behavioral health center by screening for ACEs upon all admissions into …

The Association Between Loneliness With Increased Mental Health Problems And Substance Use During The Covid-19 Pandemic In Richmond, Virginia, Angela C. Liu, Connor Cox, Mariam Sankoh, James Clifford, Courtney T. Blondino, Chanel Bea, Chimere Miles, Kim Young, Sherika Gillison-Chew, John Richardson-Lauve, Candice Turner, Elizabeth Prom-Wormley

Virginia Journal of Public Health

Background. The COVID-19 pandemic caused significant psychological distress among U.S. adults leading to increased rates of adverse mental health symptoms and substance use. This study aims to evaluate the consistency of the association between loneliness and increased mental health problems and substance use in Richmond, VA during the COVID-19 pandemic.

Methods. Data were collected in two phases: 1) internet-based surveys from August 2020 to March 2021 (N=327) and 2) paper-pencil surveys from May to October 2021 (N=225). Logistic regression was used to test the association between loneliness and increased mental health and substance use, while adjusting for sociodemographic factors and …

Resistant Maltodextrin Consumption In A Double-Blind, Randomized, Crossover Clinical Trial Induces Specific Changes In Potentially Beneficial Gut Bacteria, Volker Mai, Alyssa M Burns, Rebecca J Solch, Jennifer C Dennis-Wall, Maria Ukhanova, Bobbi Langkamp-Henken

Faculty, Staff and Student Publications

Background: We have previously reported that the addition of resistant maltodextrin (RMD), a fermentable functional fiber, to the diet increases fecal weight as well as the amount of fecal bifidobacteria. Here, we report on the targeted analysis of changes in potentially beneficial gut bacteria associated with the intervention. Objective: The primary objective of this study was to determine the effect of adding 0, 15 and 25 g RMD to the diets of healthy free-living adults on potentially beneficial gut bacteria. Methods: We expanded on our previously reported microbiota analysis in a double-blind, placebo-controlled feeding study (NCT02733263) by performing additional qPCR …

Development And Multimodal Validation Of A Substance Misuse Algorithm For Referral To Treatment Using Artificial Intelligence (Smart-Ai): A Retrospective Deep Learning Study, Majid Afshar, Brihat Sharma, Dmitriy Dligach, Madeline Oguss, Randall Brown, Neeraj Chhabra, Hale M. Thompson, Talar Markossian, Cara Joyce, Matthew M. Churpek, Niranjan S. Karnik

Biostatistics Collaborative Core: Faculty Publications and Other Works

Background: Substance misuse is a heterogeneous and complex set of behavioural conditions that are highly prevalent in hospital settings and frequently co-occur. Few hospital-wide solutions exist to comprehensively and reliably identify these conditions to prioritise care and guide treatment. The aim of this study was to apply natural language processing (NLP) to clinical notes collected in the electronic health record (EHR) to accurately screen for substance misuse.

Methods: The model was trained and developed on a reference dataset derived from a hospital-wide programme at Rush University Medical Center (RUMC), Chicago, IL, USA, that used structured diagnostic interviews to manually screen …

Understanding Psychiatric Patients’ Experience Of Virtual Animal-Assisted Therapy Sessions During The Covid-19 Pandemic, Haley Scheck, Linzi Williamson, Colleen A. Dell

People and Animals: The International Journal of Research and Practice

Canine animal-assisted therapy (AAT) can improve the mental health and well-being of incarcerated individuals. An in-person AAT program has been offered at the Regional Psychiatric Center (RPC) in Saskatoon, Canada, since 2014 with St. John Ambulance Therapy Dog Program (SJATDP) dog and handler teams. The program transitioned, for the first time, to a virtual format with the onset of the COVID-19 pandemic in March 2020. This exploratory research examines whether and how a virtual offering of AAT at RPC can provide positive benefits to forensic psychiatric patients. Overall, the findings reveal an understanding of the virtual sessions from patient, handler, …

A Music-Therapy Robotic Platform For Children With Autism: A Pilot Study, Huanghao Feng, Mohammad H. Mahoor, Francesca Dino

Electrical and Computer Engineering: Faculty Scholarship

Children with Autism Spectrum Disorder (ASD) experience deficits in verbal and nonverbal communication skills including motor control, turn-taking, and emotion recognition. Innovative technology, such as socially assistive robots, has shown to be a viable method for Autism therapy. This paper presents a novel robot-based music-therapy platform for modeling and improving the social responses and behaviors of children with ASD. Our autonomous social interactive system consists of three modules. Module one provides an autonomous initiative positioning system for the robot, NAO, to properly localize and play the instrument (Xylophone) using the robot’s arms. Module two allows NAO to play customized songs …

A Qualitative Study On Nurse Facilitators Of Mind-Body Skills Groups, Paula D. Blake-Beckford

Mindfulness Studies Theses

The Center for Mind-Body Medicine (CMBM), founded by Dr. James Gordon, provides communities with evidence-based Mind-Body Skills Groups (MBSGs) that foster self-care, self-awareness, and self-expression. MBSGs range from 8 to 12-week series on various mind-body practices wherein group members meet, practice, and reflect on the impact of mind-body skills in their lives. Research has demonstrated that participants in MBSGs have positive outcomes. Healthcare professionals (HCPs), especially nurses, gain resiliency from MBSGs. As facilitators of MBSGs, nurses develop essential skills transferable to clinical and educational settings. MBSGs are therapeutic for adult participants with chronic stress. Prior to this thesis, only one …

Where I’M From: Internal Manifestations Among Cambodian Women Using The Expressive Arts A Literature Review, Noeun Chhim

Expressive Therapies Capstone Theses

Chronic mental illness has affected many Cambodian people, but, culturally, Cambodians aren’t accustomed to opening up and discussing their feelings, rather defining mental illness to craziness and seeking help is presumed taboo. Thus, Cambodians are often reluctant to talk about their experiences and/or their related illnesses. Though Cambodians have experienced inconceivable suffering and violence during the Khmer Rouge era, for the purpose of this thesis, I will be discussing the role of Cambodian women and investigate the extent of what they’ve witnessed and experienced. Cambodian women have suffered through many years of trauma and grief, during and after the Khmer …

The Neurobiology Of The Healing Arts: Expressive Arts Therapy As An Effective Treatment For Adults Diagnosed With Complex Ptsd Due To Complex Trauma In Childhood: A Literature Review, Cheryl Ratliff

Expressive Therapies Capstone Theses

Empirically based therapies for posttraumatic stress disorder (PTSD) have been found to be less effective in treating more severe trauma presentations such as complex PTSD (CPTSD). Neurobiological investigation provides a framework for examining the physical and psychological effects of trauma on brain and nerve structures and provides insight into how to effectively treat CPTSD. This literature review examined symptomology of CPTSD resulting from complex trauma in childhood, neurobiological effects of trauma and their implications for treatment, and the efficacy of the current treatment models, primarily those of eye movement desensitization and reprocessing (EMDR), narrative exposure therapy (NET), and somatic psychotherapies. …

Drama Therapy Interventions That Support Students With Asd During Covid-19, Olivia Reyes

Expressive Therapies Capstone Theses

Due to the coronavirus (COVID-19) pandemic that began in December 2019, many people experienced traumatic losses, environmental stressors, and overall daily challenges. One of the populations most at risk during this time were those with an autism spectrum disorder (ASD). Those with mental health illness and developmental differences are experiencing the pandemic in different ways. Individuals with ASD tend to have both developmental differences and mental health challenges that motivate individuals to seek medicinal and therapeutic help, along with other services to support their daily needs. This literature review addresses the negative and positive impacts COVID-19 has had on the …

Finding A Middle Path: Using Expressive Arts Therapy To Engage Adolescents In Dialectical Behavior Therapy: A Literature Review, Rebecca Miller

Expressive Therapies Capstone Theses

This critical literature review explores the limited research on integrating expressive arts therapy (ExTH) with dialectical behavior therapy (DBT). DBT, an evidence-based, third-wave cognitive-behavioral intervention, has been adapted for use with adolescents struggling with emotional and behavioral dysregulation. Yet, the didactic and almost rigid nature of DBT can feel more like a school lesson and less like therapy, making it difficult for adolescents to engage with the treatment. This is problematic as DBT's effectiveness requires the client to be fully committed and willing to engage in the therapy. This paper explores the literature on combining ExTH with DBT and conceptual …

The Use Of Violin Family Instruments In Music Therapy With Individuals Experiencing Acute Psychiatric Presentations: A Literature Review, Brianna Rzeznik

Expressive Therapies Capstone Theses

This literature review seeks to better understand the unique ways in which the four contemporary violin family instruments - violin, viola, cello, and double bass - can be used in music therapy with individuals experiencing mania, psychosis, and dissociation. In this paper, I explore the ways in which these four instruments have been used throughout Western music history and the different roles assigned to them by composers, as well as the ways in which they are used in music therapy today. I then explore the acute psychiatric presentations of mania, psychosis, and dissociation, and the treatments and goals that tend …

A Group Music Therapy Method To Promote Mentalization Skills In Clients With Narcissistic Personality Disorder, Lisa Riggs Hobbs

Expressive Therapies Capstone Theses

Abstract

This paper investigates the development of a group music therapy method by adapting elements of mentalization-based treatment (MBT) to help clients with narcissistic personality disorder (NPD). A prominent characteristic of NPD is a deficiency in empathy. The fostering of empathy and emotional awareness forms the basis of MBT. Music therapy offers a means to explore these skills on a nonverbal level. This work is even more impactful in a group setting. Unfortunately, there is a dearth of literature specific to music therapy and NPD. Furthermore, despite the availability of writings separately concerning NPD, MBT, group therapy, and music therapy, …