Mental and Social Health Commons^™

The Risk For Malignancy Using The Milan Salivary Gland Classification Categories: A 5-Year Retrospective Review, Sara Monfared, Joshua J Weis, Shinil K Shah, Daniel J Scott, Melissa M Felinski, Erik B Wilson

Faculty, Staff and Student Publications

BACKGROUND: The field of bariatric surgery has seen peaks and troughs in the types of metabolic procedures performed. Our primary aim was to evaluate bariatric case volumes among fellows enrolled in bariatric Fellowship Council (FC)-accredited programs. Our secondary aim was to assess trends in revisional case volumes.

METHODS: We reviewed de-identified FC case logs for all bariatric surgery-accredited programs from 2010 through 2019. The number of primary sleeve gastrectomy, gastric band, gastric bypass, biliopancreatic diversion, and major revisional bariatric surgical procedures (defined as a revision with creation of a new anastomosis) were graphed for each academic year. Fellows were stratified …

Sibling Experiences With Autism Spectrum Disorder: A Hermeneutic Phenomenological Analysis, Katherine Golden

Dissertations

This study explored the lived experiences of adult siblings of a child with autism utilizing the framework of ambiguous loss theory (Boss, 1999). An exploratory analysis of the sibling experience began with the research question: What are the lived experiences of adult siblings of individuals diagnosed with autism spectrum disorder? Further analysis used the theoretical framework of ambiguous loss theory with the secondary question: How have adult siblings been affected by ambiguous loss in their experiences with a sibling with autism spectrum disorder? Heidegger’s (1962) hermeneutic phenomenological approach was utilized to guide the semi structured in-depth interviews and to analyze …

Medication-Induced Mood Disorders Following Epidural Steroid Injections In Patients With Pain: A Case Series, Christian T Vangeison, Joseph P Roys, Marissa N Catalanotto, Wyatt I Kupperman, Alexander R Kovacs, Dan Sebastian Dîrzu, Emanuel N Husu

Faculty, Staff and Students Publications

KEY CLINICAL MESSAGE: Medication-induced mood disorders following epidural steroid injections are possible therefore should be disclosed to the patient.

ABSTRACT: Medication-induced mood disorders have been rarely reported following epidural steroid injections (ESI). This case series presents three patients who met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for substance/medication-induced mood disorder after an ESI. In considering a candidacy for ESI, the rare but significant, side effects of psychiatric side effects should be disclosed to patients.

Promoting Ocd Wellness And Resilience (Power) Study: Rationale, Design, And Methods, Jessica D Leuchter, Minjee Kook, Daniel A Geller, Alyssa G Hertz, Jessica Garcia, Erika S Trent, Tracey Dibbs, Ogechi Onyeka, Wayne K Goodman, Andrew G Guzick, Andrew D Wiese, Amanda D Palo, Brent J Small, H Blair Simpson, Lauren K Havel, Sohail A Nibras, Kirti Saxena, Eric A Storch

Faculty, Staff and Students Publications

Obsessive-compulsive disorder (OCD) affects 1-2% of children and is associated with functional impairment and diminished quality of life. Several treatments are efficacious: cognitive behavioral therapy (CBT) with exposure and response prevention, serotonin reuptake inhibitor (SRI) monotherapy, and combined treatment (SRI + CBT). Expert clinician-informed practice parameters suggest that youth with mild to moderate OCD should be treated initially with CBT yet SRIs are frequently employed as the first-line intervention or in combination with psychotherapy in applied practice. Empirical data to guide SRI discontinuation in pediatric OCD are very limited. This study, Promoting OCD Wellness and Resiliency (POWER), aims to address …

Promoting Ocd Wellness And Resilience (Power) Study: Rationale, Design, And Methods, Jessica D Leuchter, Minjee Kook, Daniel A Geller, Alyssa G Hertz, Jessica Garcia, Erika S Trent, Tracey Dibbs, Ogechi Onyeka, Wayne K Goodman, Andrew G Guzick, Andrew D Wiese, Amanda D Palo, Brent J Small, H Blair Simpson, Lauren K Havel, Sohail A Nibras, Kirti Saxena, Eric A Storch

Faculty, Staff and Students Publications

Obsessive-compulsive disorder (OCD) affects 1-2% of children and is associated with functional impairment and diminished quality of life. Several treatments are efficacious: cognitive behavioral therapy (CBT) with exposure and response prevention, serotonin reuptake inhibitor (SRI) monotherapy, and combined treatment (SRI + CBT). Expert clinician-informed practice parameters suggest that youth with mild to moderate OCD should be treated initially with CBT yet SRIs are frequently employed as the first-line intervention or in combination with psychotherapy in applied practice. Empirical data to guide SRI discontinuation in pediatric OCD are very limited. This study, Promoting OCD Wellness and Resiliency (POWER), aims to address …

Distinguishing Renal Cell Carcinoma From Normal Kidney Tissue Using Mass Spectrometry Imaging Combined With Machine Learning, Vishnu Shankar, Kanchustambham Vijayalakshmi, Rosalie Nolley, Geoffrey A Sonn, Chia-Sui Kao, Hongjuan Zhao, Ru Wen, Livia S Eberlin, Robert Tibshirani, Richard N Zare, James D Brooks

Faculty, Staff and Students Publications

PURPOSE: Accurately distinguishing renal cell carcinoma (RCC) from normal kidney tissue is critical for identifying positive surgical margins (PSMs) during partial and radical nephrectomy, which remains the primary intervention for localized RCC. Techniques that detect PSM with higher accuracy and faster turnaround time than intraoperative frozen section (IFS) analysis can help decrease reoperation rates, relieve patient anxiety and costs, and potentially improve patient outcomes.

MATERIALS AND METHODS: Here, we extended our combined desorption electrospray ionization mass spectrometry imaging (DESI-MSI) and machine learning methodology to identify metabolite and lipid species from tissue surfaces that can distinguish normal tissues from clear cell …

A Case Report Of Unusual Presentation Of A Rare Renal Tumor, Farzaneh Sharifiaghdas, Behzad Narouie, Mohammad Ghasemi-Rad, Fatemeh Moosavian, Mohadese Ahmadzade, Hamidreza Rouientan

Faculty, Staff and Students Publications

There are very few cases of primary renal Ewing sarcomas, which are characterized by a high rate of metastasis. These tumors are often mistaken for other more common kidney tumors due to their rarity and lack of pathognomonic symptoms in the early stages. A 28-year-old male patient presented to our clinic with a 2-month history of nonproductive progressive cough and left flank pain. The chest was scanned with contrast-enhanced computed tomography, which showed a heterogeneously enhancing mass with central vascularity on the left retroperitoneal. An abdominal dynamic multiphasic magnetic resonance imaging with contrast revealed a large mass that was highly …

Thirty-Day Outcomes Of Resolute Onyx Stent For Symptomatic Intracranial Stenosis: A Multicenter Propensity Score-Matched Comparison With Stenting Versus Aggressive Medical Management For Preventing Recurrent Stroke In Intracranial Stenosis Trial, Farhan Siddiq, Ravi S Nunna, Jonathan M Beall, Inamullah Khan, Musharaf Khan, Wondwossen G Tekle, Mohamad Ezzeldin, Omar Tanweer, Jan-Karl Burkhardt, Pascal M Jabbour, Stavropoula I Tjoumakaris, Nabeel A Herial, Adnan H Siddiqui, Ramesh Grandhi, Renee L Martin, Adnan I Qureshi, Ameer E Hassan

Faculty, Staff and Students Publications

BACKGROUND: Symptomatic intracranial atherosclerotic disease (sICAD) is estimated to cause 10% of strokes annually in the United States. However, treatment remains a challenge with several different stenting options studied in the past with unfavorable results.

OBJECTIVE: To report the 30-day stroke and/or death rate associated with intracranial stent placement for sICAD using Resolute Onyx Zotarolimus-Eluting Stent (RO-ZES) and provide a comparison with the results of Stenting Versus Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial.

METHODS: Prospectively maintained databases across 8 stroke centers were used to identify adult patients treated with RO-ZES for sICAD between January …

Imaging Of Pediatric Cardiac Tumors: A Cog Diagnostic Imaging Committee/Spr Oncology Committee White Paper, Cara E Morin, Lindsay M Griffin, Rebecca S Beroukhim, Pablo Caro-Domínguez, Sherwin Chan, Jason N Johnson, Juan C Infante, Christopher Z Lam, Ladonna J Malone, Elizabeth R Tang, Michael D Taylor, James C Wilkinson, Prakash M Masand

Faculty, Staff and Students Publications

Cardiac tumors in children are rare and the majority are benign. The most common cardiac tumor in children is rhabdomyoma, usually associated with tuberous sclerosis complex. Other benign cardiac masses include fibromas, myxomas, hemangiomas, and teratomas. Primary malignant cardiac tumors are exceedingly rare, with the most common pathology being soft tissue sarcomas. This paper provides consensus-based imaging recommendations for the evaluation of patients with cardiac tumors at diagnosis and follow-up, including during and after therapy.

Safety And Efficacy Of A Kaolin-Impregnated Hemostatic Gauze In Cardiac Surgery: A Randomized Trial, Mubashir Mumtaz, Richard B Thompson, Marc R Moon, Ibrahim Sultan, T Brett Reece, William B Keeling, Jacob Delarosa

Faculty, Staff and Students Publications

OBJECTIVE: A kaolin-based nonresorbable hemostatic gauze, QuikClot Control+, has demonstrated effective hemostasis and safety when used for severe/life-threatening (grade 3/4) internal organ space bleeding. We evaluated the efficacy and safety of this gauze for mild to moderate (grade 1-2) bleeding in cardiac surgery compared with control gauze.

METHODS: This was a randomized, controlled, single-blinded study of patients who underwent cardiac surgery between June 2020 and September 2021 across 7 sites with 231 subjects randomized 2:1 to QuikClot Control+ or control. The primary efficacy end point was hemostasis rate (ie, subjects achieving grade 0 bleed) through up to 10 minutes of …

Declining Autozygosity Over Time: An Exploration In Over 1 Million Individuals From Three Diverse Cohorts, Sarah M C Colbert, Frank R Wendt, Gita A Pathak, Drew A Helmer, Elizabeth R Hauser, Matthew C Keller, Renato Polimanti, Emma C Johnson

Faculty, Staff and Students Publications

Previous studies have hypothesized that autozygosity is decreasing over generational time. However, these studies were limited to relatively small samples (n < 11,000) lacking in diversity, which may limit the generalizability of their findings. We present data that partially support this hypothesis from three large cohorts of diverse ancestries, two from the US (All of Us, n = 82,474; the Million Veteran Program, n = 622,497) and one from the UK (UK Biobank, n = 380,899). Our results from a mixed-effect meta-analysis demonstrate an overall trend of decreasing autozygosity over generational time (meta-analyzed slope = -0.029, SE = 0.009, p = 6.03e-4). On the basis of our estimates, we would predict F

Adverse Childhood Experiences In Mothers And Their Children With Hearing Loss, Elizabeth A. Rosenzweig

Journal of Early Hearing Detection and Intervention

This study examined the relationship between maternal and child ACEs in children with hearing loss ages 3-12. One hundred twenty-four mother-child dyads completed assessments of mother and child ACEs. Adverse cChildhood eExperiences (ACEs) were measured using the Center for Youth Wellness Adverse Childhood Experiences Questionnaire (CYW ACE-Q; Burke Harris & Renschler, 2015).

Both maternal and child participants in this study reported higher levels of ACE exposure than previously reported in studies of the general population. Maternal and child ACEs were significantly correlated. White/Caucasian mothers experienced significantly fewer ACEs than mothers of other races/ethnicities. Children living in adoptive, foster, or guardianship …

Effectiveness Of Couples-Based Exposure And Response Prevention (Erp) Therapy Vs. Individual Erp Treatment For Ocd Symptom Reduction And Overall Couple Satisfaction, Priscilla Nguyen, Shana O'Connor-Wolf

School of Psychology, Family, and Community Research Conference

Obsessive-Compulsive Disorder (OCD) is a debilitating, chronic condition characterized by recurrent intrusive thoughts followed by persistent behavioral urges and time-consuming rituals that attempt to neutralize anxiety and distress caused by those unwanted obsessive thoughts (American Psychiatric Association, 2013). This research study aims to explore the effectiveness of Couples-Based ERP in decreasing individual symptoms of OCD and evaluating the impact of treatment on relationship satisfaction. Using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and the Dyadic-Adjustment Scale (DAS) to measure our constructs, we hypothesize that Couples-Based ERP will be effective in not only decreasing OCD symptoms, but also increasing overall relationship satisfaction.

A Systematic Review Of Bottom-Up And Top-Down Psychotherapy Methods For The Treatment Of Posttraumatic Stress Disorder (Ptsd), Kristen Sievert

School of Psychology, Family, and Community Research Conference

While numerous studies have investigated the efficacy of either Top-Down or Bottom-Up modalities in reducing PTSD symptoms, there is a paucity of research focused on comparing differences in treatment effects of Bottom-Up and Top-Down therapies. Top-Down interventions are built on an individual’s ability to become conscious of their thoughts and their subsequent capacity to change those thoughts, while Bottom-Up interventions rely on an individual’s body sensations an/or movements to access and process trauma. We investigated this gap by conducting a systematic review of Top-down and Bottom-up treatments for PTSD. To be included in the review, studies needed to examine adults …

The Effectiveness Of Combining Play Therapy With Emotionally Focused Family Therapy For The Treatment Of Children, Ages 3-6., Britney Roark

School of Psychology, Family, and Community Research Conference

Present literature on emotionally focused family therapy (EFFT) overlooks treatment involving young children (Willis et al., 2016). Because preschool-aged children learn and express emotion best through the medium of play (Schaefer & Drewes, 2011), I hypothesize that EFFT will prove most effective with children ages 3-6 when combined with play therapy techniques. Marriage and family therapy interns, trained in EFFT concepts, who treat children in this age group will complete a training course on combining play therapy with EFFT. A control group will not. Initial and final measures will determine the success of treatment over a 12-week period.

Efficacy Of Solution Focused Therapy With At Risk Youth, Garret Patterson

School of Psychology, Family, and Community Research Conference

Dating back to the 1980’s, Solution Focused Brief Therapy (SFBT) is a therapy approach that helps clients put problems in their life into context as measurable, manageable, and fixable. For many, this solution forward approach helps to improve symptoms and resolve stuck behavior patterns often stemming from childhood. This client driven, not knowing approach helps clients discover their own autonomy and understand that not only are their problems solvable, but that they themselves have the internal resources by which to solve them. However, there is still much interest as to who can benefit most from this form of therapy. However, …

Engagement In Religious Activity Compared To Peer Support: An Intervention For Suicidal Ideation Among High School Students., Meradythe Edson, Natalie Goobes, Danielle Thayer

School of Psychology, Family, and Community Research Conference

Suicidal ideation (SI) can lead to suicide. Suicide is the second leading cause of death among children ages 10-14 and the third leading cause of death among adolescents ages 15-24 (CDC). This study compares active engagement in religious activities versus peer support as an effective resource in decreasing SI among high school students in the United States. The research explains how active engagement in religious activities will produce better results than peer support alone for decreasing SI in the targeted population. Semi-structured interviews of high school students and self-report questionnaires are utilized in this study. Our research hopes to support …

The Effectiveness Of Video Game Therapy In Helping Adolescent Clients To Build Connections With Their Families, Qichang Yang

School of Psychology, Family, and Community Research Conference

This study explores the role of video game therapy in enhancing family connections among adolescents. Using a mixed-methods approach, we use surveys and interviews to assess changes in family relationships for adolescents undergoing video game therapy. Preliminary findings indicate that video game therapy could be a great tool for improving familial bonds. This research adds to the understanding of non-traditional therapeutic interventions and their potential impact on family dynamics and adolescent mental health.

Impacts Of Receiving An Autism Spectrum Diagnosis As An Adult On Relationship Satisfaction And Relationship-Specific Attachment, Erika Fisch, Molly Hammond, Katie Roberts

School of Psychology, Family, and Community Research Conference

Our research will explore how receiving an Autism Spectrum Disorder diagnosis impacts adult relationship satisfaction and relationship-specific attachment. Previous research has demonstrated benefits of ASD diagnosis for individuals. We hope to expand this body of research by examining the effects of ASD diagnosis on couples. We will survey adult couples with one partner on a waitlist for an ASD evaluation using the Dyadic Adjustment Scale and the Experiences in Close Relationships-Revised questionnaire. After evaluation, we will ask adults diagnosed with ASD and their partners to take the survey twice more. We hypothesize that both relationship satisfaction and attachment will improve.

Effectiveness Of Emotionally Focused Family Therapy (Efft) On Adolescent Non-Suicidal Self-Injury (Nssi) Vs Dialectical Behavioral Therapy For Adolescence (Dbt-A), Aneta Merlino

School of Psychology, Family, and Community Research Conference

This study aims to explore the effectiveness of Emotionally Focused Family Therapy (EFFT) in reducing the incidence of adolescent Non-Suicidal Self Injury (NSSI). 80 adolescents who meet the NSSI criteria, age 13-19, will be randomized to participate in a total of 12 weekly, in-person EFFT sessions, or 16 weekly in-person Dialectical Behavioral Therapy for Adolescence (DBT-A) sessions. It is hypothesized EFFT will be more effective in long term reduction of NSSI frequency, measured post treatment, and at 12 month follow up, due to an increase in interpersonal protective factors as compared to DBT-A.