Mental and Social Health Commons^™

Early Postpartum Hba1c After Hyperglycemia First Detected In Pregnancy-Imperfect But Not Without Value, Ankia Coetzee, David R Hall, Mari Van De Vyver, Magda Conradie

Faculty, Staff and Student Publications

BACKGROUND: South African women of childbearing age are disproportionally affected by obesity and at significant risk of Type 2 Diabetes Mellitus (T2DM). Unless pregnant, they do not readily undergo screening for T2DM. With a local focus on improved antenatal care, hyperglycemia is often first detected in pregnancy (HFDP). This may erroneously be attributed to Gestational Diabetes Mellitus (GDM) in all without considering T2DM. Glucose evaluation following pregnancy is essential for early detection and management of women with T2DM in whom persistent hyperglycemia is to be expected. Conventional testing with an oral glucose tolerance test (OGTT) is cumbersome, prompting investigation for …

The Novel Uncompetitive Nmda Receptor Antagonist Esmethadone (Rel-1017) Has No Meaningful Abuse Potential In Recreational Drug Users, Megan J Shram, Jack E Henningfield, Glen Apseloff, Charles W Gorodetzky, Sara De Martin, Frank L Vocci, Frank L Sapienza, Thomas R Kosten, Jeff Huston, August Buchhalter, Judy Ashworth, Ryan Lanier, Franco Folli, Andrea Mattarei, Clotilde Guidetti, Stefano Comai, Cedric O'Gorman, Sergio Traversa, Charles E Inturrisi, Paolo L Manfredi, Marco Pappagallo

Faculty, Staff and Students Publications

Esmethadone (REL-1017) is the opioid-inactive dextro-isomer of methadone and a low-affinity, low-potency uncompetitive NMDA receptor antagonist. In a Phase 2, randomized, double-blind, placebo-controlled trial, esmethadone showed rapid, robust, and sustained antidepressant effects. Two studies were conducted to evaluate the abuse potential of esmethadone. Each study utilized a randomized, double-blind, active-, and placebo-controlled crossover design to assess esmethadone compared with oxycodone (Oxycodone Study) or ketamine (Ketamine Study) in healthy recreational drug users. Esmethadone 25 mg (proposed therapeutic daily dose), 75 mg (loading dose), and 150 mg (Maximum Tolerated Dose) were evaluated in each study. Positive controls were oral oxycodone 40 mg …

Identity And Body Image: How Bicultural Influences Affect The Development Of Negative Body Image And Disordered Eating In Korean American Adolescents, Abigail G. Brown

Honors Projects

The objective of this research project is to examine the existing literature related to culture, body image, and disordered eating in Korea and the United States as they are related to the identity and body image formation of Korean American adolescents in the United States. Because there is not much existing literature specifically investigating the experience of Korean American adolescents, this paper aims to synthesize the current research regarding Korean and United States culture to create a summary of factors that contribute to the development of negative body image and/or disordered eating in this population. In addition, these factors will …

Bipolar Disorder In Children (Including Gifted And 2e Children), Ed Malin

Graduate Student Independent Studies

Between the publication of the Diagnostic and Statistical Manual of Mental Disorders (DSM) in 1952 and the DSM-IV in 1993, 277 new disorders were created and made available for life-altering diagnoses. Should it be surprising that, since the late 1990s, psychiatrists in the United States have invented the diagnosis of Childhood-onset Bipolar Disorder? Common practice before that time (and still, in Europe) was that 18 was the earliest age of onset for Bipolar Disorder, based on extensive observation and family history. While lithium and anticonvulsants had been in use to treat adults with Bipolar Disorder, by the late 1990s children …

Effects Of Daylight On College Students’ Physical And Mental Well-Being, Sathya Thenappan

Quantitative Social Science Undergraduate Senior Theses

While existing literature predominantly deals with the impact of daylight on adults in general and more specifically at the workplace, less is known about its impact on the college student demographic and daylight exposure levels at college residences. Given its considerable impact on both the physical and mental well-being of individuals, daylight has been used in the treatment of an assortment of diseases from seasonal affective disorder to depression. With college students constituting the majority of today’s people who suffer from mental health issues in society, uncovering the link between daylight exposure and its impact on the physical and mental …

Digital Health Technologies For Peripartum Depression Management Among Low-Socioeconomic Populations: Perspectives From Patients, Providers, And Social Media Channels, Alexandra Zingg, Tavleen Singh, Amy Franklin, Angela Ross, Sudhakar Selvaraj, Jerrie Refuerzo, Sahiti Myneni

Faculty, Staff and Student Publications

BACKGROUND: Peripartum Depression (PPD) affects approximately 10-15% of perinatal women in the U.S., with those of low socioeconomic status (low-SES) more likely to develop symptoms. Multilevel treatment barriers including social stigma and not having appropriate access to mental health resources have played a major role in PPD-related disparities. Emerging advances in digital technologies and analytics provide opportunities to identify and address access barriers, knowledge gaps, and engagement issues. However, most market solutions for PPD prevention and management are produced generically without considering the specialized needs of low-SES populations. In this study, we examine and portray the information and technology needs …

Moving At The Speed Of Trust, Sun Ho Lee

Masters Theses

Moving at the Speed of Trust is a workbook of strategies — practices, definitions, and techniques — to nurture community-building in support of inbetweeners who live between power structures and cultures and are often left out. Inbetweeners are those individuals whose lives are in transition through recent immigration or forced translocation from Asia to America.

These strategies revolve around threads of trust: kin, giggles, vulnerability, and shared experience. With these threads, we can question power. We can preserve stories, expand the ways we connect, shift perspectives on what is “standard,” and cultivate a community rooted in understanding. To understand each …

The Meaning Of A Choice, Julie-Louise Zeitoun

Masters Theses

If you are disabled or disadvantaged, you will be dismissed and stifled. Few people will actively care for your struggles. As a person with autism, I was deeply fearful of the persecution I had faced throughout my life; it was a fear that followed me with terrifying determination. I desperately wanted to blend into society. So I designed myself to be devoid of any weakness, and productivity was the way I chose to conceal any difficulties I faced. It was a way to measure my success — a way to measure my normalcy.

Standard medical textiles are generic, cumbersome devices. …

Effects Of Controllability And Language On Stigma Toward Mental Illness, Claire E. Shaver, Kevin M. Summers, Gina A. Paganini, E. Paige Lloyd

Undergraduate Theses, Capstones, and Recitals

Although past work consistently demonstrates perceivers stigmatize mental illness; which dimensions of stigma are relevant for specific conditions remains debated (Brohan et al., 2010). In the current work, we manipulated (between subjects) the controllability of fictitious mental illnesses and examined participants stigmatization across six dimensions (Fear, Help, Forcing Treatment, and Negative Emotions; Brown, 2008). We also examined whether effects of controllability were moderated by language (within subjects; person-first vs identity-first). We consistently found effects of controllability such that participants in the low (compared to high) condition responded with more fear, empathy, negative emotion, and intention to force treatment, but also …

Evaluation Of Feasibility And Acceptability Of A Web-Based Diabetes Prevention Program (Dpp) For Diabetes Risk Reduction In Chinese Americans In New York City, Ming-Chin Yeh, Wincy Lau, Claire Anselmo Keady, Margrethe Horlyck-Romanovsky, Ho-Jui Tung, Lu Hu, Grace X. Ma, Judith Wylie-Rosett

Health Policy & Community Health: Faculty Publications

Introduction: Intensive lifestyle intervention remains an effective modality to reduce diabetes incidence and delay the progression to type 2 diabetes. The primary aim of this study was to pilot-test the feasibility and acceptability of a culturally and linguistically tailored web-based DPP intervention among Chinese Americans with prediabetes living in New York City.

Methods: Thirteen Chinese American participants with prediabetes were recruited to complete a 1-year web-based Diabetes Prevention Program (DPP) lifestyle intervention. Quantitative and qualitative measures such as retention rate and data collected from web-based questionnaires and focus groups were collected and analyzed to assess study feasibility and …

Prevalence And Predictors Of Suicidality Among Adults Initiating Office-Based Buprenorphine., Michelle R. Lent, Karen L Dugosh, Emily Hurstak, Hannah R. Callahan, Kimberly Mazur, Greater Philadelphia Opioid Use Disorder Research Group

PCOM Scholarly Works

BACKGROUND: Individuals who have substance use disorders may have an elevated risk of suicidality. This study sought to examine the prevalence of, and identify factors associated with, suicidality in adults with opioid use disorder (OUD) initiating office-based buprenorphine treatment.

METHODS: Individuals were eligible to participate if they had OUD and had initiated treatment in the past month. Participants (n = 244) completed a semi-structured interview using the Addiction Severity Index-Lite.

RESULTS: At baseline, 37.70% of participants reported significant thoughts of suicide over their lifetime and 27.46% reported suicidal attempts over their lifetime. Logistic regression analyses were used to identify predictors …

Unilateral Agenesis Of Adnexa, Srinidhi Govindarajan, Poornima M Associate Professor, Rashmi H.S., Aishwarya Bhat

Digital Journal of Clinical Medicine

No abstract provided.

A Qualitative Inquiry Of Experiences Of Hiv-Related Stigma And Its Effects Among People Living With Hiv On Treatment In Rural Kilifi, Kenya, Stanley Wechuli Wanjala, Moses Nyongesa, Rachael Mapenzi, Stanley Luchters, Amina Abubakar

Institute for Human Development, East Africa

Background: The pervasiveness of HIV-related stigma and discrimination, and its consequences on HIV prevention and treatment, have been well documented. However, little is known about the lived experiences of HIV-related stigma and its effects among the general adult population living with HIV in rural African settings. This study set out to explore this knowledge gap.

Methods: From April to June 2018, we conducted in-depth interviews with a convenience sample of 40 adults living with HIV aged 18–58 years in Kilifi, Kenya. A semi-structured interview guide was used to explore experiences of HIV-related stigma and its impact on these adults. …

Patient Engagement In A Multimodal Digital Phenotyping Study Of Opioid Use Disorder, Cynthia I. Campbell, Ching-Hua Chen, Sara R. Adams, Asma Asyyed, Ninad R. Athale, Monique B. Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C. Jacobson, Heather K. Jones, David Kotz, Chantal A. Lambert-Harris, Zhiguo Li, Bethany Mcleman, Varun Mishra, Catherine Stanger, Geetha Subramaniam, Weiyi Wu, Christopher Zegers, Lisa A. Marsch

Dartmouth Scholarship

Background: Multiple digital data sources can capture moment-to-moment information to advance a robust understanding of opioid use disorder (OUD) behavior, ultimately creating a digital phenotype for each patient. This information can lead to individualized interventions to improve treatment for OUD.

Objective: The aim is to examine patient engagement with multiple digital phenotyping methods among patients receiving buprenorphine medication for OUD.

Methods: The study enrolled 65 patients receiving buprenorphine for OUD between June 2020 and January 2021 from 4 addiction medicine programs in an integrated health care delivery system in Northern California. Ecological momentary assessment (EMA), sensor data, and social media …

Social Identities And Campus Belonging As Predictors Of Flourishing Among College Students, Christine Gilchrist

Dissertations, Theses, and Capstone Projects

Annual data since 2012 shows college students’ flourishing (a measure of psychological well-being) in continuous decline, with 2022 showing the largest decrease. Since the knowledge base of the predictors of flourishing is limited, how college executives can best address this issue is unclear. Variations in flourishing have been observed in studies that examined the relationship between food insecurity (DeBate et al., 2021), race/ethnicity (Lipson et al., 2018, 2022; Nyunt et al., 2022; Parr, 2022), immigration status (Cadenas & Nienhusser, 2021), as well as gender identity and sexual orientation (Parr, 2022). The intersectional impact of demographic and social identities has not …

The Co-Occurrence Of Adverse Childhood Experiences And Mental Health Among Latina/O Adults: A Latent Class Analysis Approach, Michael Niño, Kazumi Tsuchiya, Shaun Thomas, Christian Vazquez

Sociology and Criminology Faculty Publications and Presentations

Adverse childhood experiences (ACEs) have been linked to poor mental health among Latina/os. Few studies, however, have attempted to understand the extent to which ACEs co-occur and whether different forms of ACE co-occurrence differentially shape poor mental health patterns among Latina/os. The present study begins to address this gap by (1) identifying latent classes of ACEs and (2) determining whether and how different ACE classes shape high depressive symptoms among Latina/o adults. Data were drawn from two waves of the Hispanic Community Health Study/Study of Latinos, a longitudinal, community-based sample of Latina/os living in four urban communities. Latent Class Analysis …

"I Stayed There The Whole Night": Exploring Caregivers' Experiences With The Healthcare System When Caring For A Parent At The End Of Life, Lillian Mehran

Dissertations and Theses

Background: In the United States, there are nearly 53 million individuals serving as caregivers to a loved one. Half of all caregivers are caring for a parent or parent-in-law, and 79% of caregivers are caring for a person aged 50 or older. In New York State, there are an estimated 4.1 million caregivers who collectively provide over 2.6 billion hours of unpaid care, with those caring for a person at the end of life providing twice as many hours of caregiving per week compared to other caregivers. The number of individuals requiring caregiving is expected to increase as a significant …

Side-Stepping God: How The Nonreligious Find Success In Alcoholics Anonymous, Caitlin Trombley

Dissertations

This dissertation utilized mixed methods research to examine how nonreligious individuals with substance use disorders navigate recovery within—or in spite of—Alcoholics Anonymous (AA). Both the 12-step program itself and Alcoholics Anonymous have long been criticized for being religious and/or spiritual in nature, and some studies have shown that this is particularly challenging for nonreligious individuals seeking recovery. The purpose of this research was to (a) identify differences in recovery resources (recovery capital) between the religious, the nonreligious, those in AA, and those who have adopted alternative forms of recovery; (b) identify barriers that the nonreligious face as they navigate recovery …

Seminarians In The Person-Of-The-Therapist (Pott) Training : A Phenomenological Study, Tomichan Moonnanappillil

Dissertations

This dissertation presented a transcendental phenomenological study conducted among eight seminarians in one of the theological schools in Southern Texas, who attended the personof-the- therapist (POTT) training program during the fall semester of 2019. This study aimed to examine seminarian participants' experiences in POTT training, their influence on their selfawareness, and their impact on their emotional maturity and the ability to make responsible life choices. The study was guided by an existential-humanistic philosophical orientation as an overarching theoretical orientation with the subjective epistemological worldview and socialconstructionism paradigm. Findings indicated POTT training positively impacted seminarian participants' human formation, which was foundational …

The Effects Of Height-For-Age And Hiv On Cognitive Development Of School-Aged Children In Nairobi, Kenya: A Structural Equation Modelling Analysis, Rachel Maina, Jia He, Amina Abubakar, Miguel Perez-Garcia, Manasi Kumar, Jelte M. Wicherts

Brain and Mind Institute

Background: Empirical evidence indicates that both HIV infection and stunting impede cognitive functions of school-going children. However, there is less evidence on how these two risk factors amplify each other’s negative effects. This study aimed to examine the direct effects of stunting on cognitive outcomes and the extent to which stunting (partially) mediates the effects of HIV, age, and gender on cognitive outcomes.

Methodology: We applied structural equation modelling to cross-sectional data from 328 children living with HIV and 260 children living without HIV aged 6–14 years from Nairobi, Kenya to test the mediating effect of stunting and predictive …