Augmenting Addiction Management: The Potential Efficacy Of Combining Rtms With Cbt,
2023
Thomas Jefferson University
Augmenting Addiction Management: The Potential Efficacy Of Combining Rtms With Cbt, Dylan Schroeder
Master of Science in Physician Assistant Studies Capstone Presentations (Center City)
Abstract
Non-substance and substance related addictive disorders contribute a high global disease burden with relatively poor treatment options with poor craving control and high relapse rates. CBT is a well-documented treatment modality which is the cornerstone for top-down behavioral management of cravings and preventing relapse, but its clinical efficacy is limited. Repetitive transcranial magnetic stimulation (rTMS) is an emerging treatment method which may reduce cravings and relapse rates through a bottom-up neurochemical approach.
There is potential that the rTMS reduction of bottom-up cravings may synergistically enhance the top-down control of cravings established with CBT. Existing primary research demonstrates that a …
Safety And Efficacy Of Adjunctive Esketamine Vs. Maois In Trd In Adults,
2023
Thomas Jefferson University
Safety And Efficacy Of Adjunctive Esketamine Vs. Maois In Trd In Adults, Riley Guinan
Master of Science in Physician Assistant Studies Capstone Presentations (Center City)
Background:
Depression affects millions globally - Treatment-resistant depression (TRD) is defined as failure to respond to two antidepressant trials of adequate dose and duration
Traditional Treatment for TRD:
Switching or adding medications atypical antipsychotics - Limitations include delayed action, side effects, and limited efficacy
Alternative Treatment Options:
- Ketamine:
- A dissociative anesthetic with potential antidepressant effects
- Targets the NMDA receptor and activates AMPA receptor.
- Shows rapid and potent antidepressant effects; however, not FDA-approved for depression
- Monoamine Oxidase Inhibitors (MAOIs):
- Antidepressants used since the 1950s
- Inhibits the enzyme metabolizing neurotransmitters.
- Limitations: Dietary restrictions and drug interactions and longstanding safety concerns …
Cognitive Skills And Dna Methylation Are Correlating In Healthy And Novice College Students Practicing Preksha Dhyāna Meditation,
2023
Thomas Jefferson University
Cognitive Skills And Dna Methylation Are Correlating In Healthy And Novice College Students Practicing Preksha Dhyāna Meditation, Bassam Abomoelak, Ray Prather, Samani U. Pragya, Samani C. Pragya, Neelam D. Mehta, Parvin Uddin, Pushya Veeramachaneni, Naina Mehta, Amanda Young, Saumya Kapoor, Devendra Mehta
Student Papers, Posters & Projects
The impact of different meditation protocols on human health is explored at the cognitive and cellular levels. Preksha Dhyana meditation has been observed to seemingly affect the cognitive performance, transcriptome, and methylome of healthy and novice participant practitioners. In this study, we performed correlation analyses to investigate the presence of any relationships in the changes in cognitive performance and DNA methylation in a group of college students practicing Preksha Dhyāna (N = 34). Nine factors of cognitive performance were assessed at baseline and 8 weeks postintervention timepoints in the participants. Statistically significant improvements were observed in six of the nine …
Beyond Economics And Politics : A Sociological Review Of Local Long-Term Care Service Provision In China,
2023
Lingnan University
Beyond Economics And Politics : A Sociological Review Of Local Long-Term Care Service Provision In China, Zhen Tian
Lingnan Theses (MPhil & PhD)
The socio-demographic transition presents a significant challenge that impacts the renewal of welfare arrangements and the reallocation of welfare responsibilities across sectors. Long-term care (LTC) services have emerged as a widely accepted strategy to promote the active daily living and human dignity of senior citizens. This study aims to assess the effective policy strategies employed in various Chinese contexts to address significant LTC policy concerns and synthesise lessons that can guide future policy decisions. The study addresses three questions to explore local variations in China's LTC service provision: (1) What differences exist in the long-term care services provision? (2) How …
Social Networks, Access To Healthcare, And The Health-Related Quality Of Life Of Young Informal Workers In Nigeria’S Construction Industry,
2023
Lingnan University
Social Networks, Access To Healthcare, And The Health-Related Quality Of Life Of Young Informal Workers In Nigeria’S Construction Industry, Ayomide Oluwaseyi Oladosu
Lingnan Theses (MPhil & PhD)
Young informal workers in Nigeria face a significant decline in their health-related quality of life (HRQoL) due to their lack of control over their employment conditions. This problem is particularly pronounced among young informal workers in the construction industry, given its precarious and hazardous nature. To enhance HRQoL, these workers primarily rely on their social networks for support. However, given the level of hazards they encounter in the construction industry, social networks alone may not be sufficient to directly improve their HRQoL. Nevertheless, social networks can facilitate access to healthcare, which in turn may enhance HRQoL. Unfortunately, limited research has …
Reminiscence Therapy For Prevention Of Post-Stroke Anxiety And Depression In Adults,
2023
Thomas Jefferson University
Reminiscence Therapy For Prevention Of Post-Stroke Anxiety And Depression In Adults, Carly Porter
Master of Science in Physician Assistant Studies Capstone Presentations (Center City)
Introduction
Anxiety and depression are prevalent after a stroke.1,2 Peer support is a non-pharmacologic intervention utilized to manage post-stroke anxiety and depression with inconsistent results.3 Reminiscence therapy is an intervention that has been studied in the dementia population but is a relatively new intervention for the stroke population and has the potential to impact the psychological care provided to stroke patients.4
Pelvic Fractures - An Overview,
2023
JSS Medical College and Hospital, JSSAHER
Pelvic Fractures - An Overview, Shashank Cheemalapati
Digital Journal of Clinical Medicine
Pelvic fractures are injuries commonly caused by high-energy trauma, such as motor vehicle accidents and falls from a height. Understanding the anatomy, mechanisms of injury, classification, diagnosis and the management of these fractures is crucial to improve patient outcomes. This short article aims to provide a comprehensive overview of the current state of knowledge regarding pelvic fractures.
Oleoylethanolamide Facilitates Pparα And Tfeb Signaling And Attenuates Aβ Pathology In A Mouse Model Of Alzheimer’S Disease,
2023
The Texas Medical Center Library
Oleoylethanolamide Facilitates Pparα And Tfeb Signaling And Attenuates Aβ Pathology In A Mouse Model Of Alzheimer’S Disease, Michele M Comerota, Manasee Gedam, Wen Xiong, Feng Jin, Lisheng Deng, Meng C Wang, Jin Wang, Hui Zheng
Faculty, Staff and Students Publications
BACKGROUND: Age is the strongest risk factor for the development of Alzheimer's disease (AD). Besides the pathological hallmarks of β-amyloid (Aβ) plaques and neurofibrillary tangles, emerging evidence demonstrates a critical role of microglia and neuroinflammation in AD pathogenesis. Oleoylethanolamide (OEA) is an endogenous lipid amide that has been shown to promote lifespan and healthspan in C. elegans through regulation of lysosome-to-nucleus signaling and cellular metabolism. The goal of our study was to determine the role of OEA in the mediation of microglial activity and AD pathology using its stable analog, KDS-5104.
METHODS: We used primary microglial cultures and genetic and …
Impact Of Mental Health Boarding In The Emergency Department And Recommendations On How We Can Improve,
2023
Thomas Jefferson University
Impact Of Mental Health Boarding In The Emergency Department And Recommendations On How We Can Improve, Kyra Buettner
Master of Science in Physician Assistant Studies Capstone Presentations (Center City)
Introduction
Every year in the United States there is an estimated 2 million adolescents who experience suicidal ideation or attempt suicide.1 The shortage of behavioral and mental health professionals has led to an increase in emergency department (ED) visits. “Boarding” is defined as “the practice of holding patients in the ED or another temporary location after the decision to admit or transfer has been made.2” The purpose of this study is to evaluate the following question - in adolescent patients with suicide attempt or mental health crisis, does boarding in the ED result in poorer mental health …
The Role Of Repetitive Transcranial Magnetic Stimulation (Rtms) V. Electroconvulsive Therapy (Ect) In Geriatric Depression Treatment: Efficacy & Tolerability,
2023
Thomas Jefferson University
The Role Of Repetitive Transcranial Magnetic Stimulation (Rtms) V. Electroconvulsive Therapy (Ect) In Geriatric Depression Treatment: Efficacy & Tolerability, Madeleine Sarro
Master of Science in Physician Assistant Studies Capstone Presentations (Center City)
Background
- Geriatric depression, or depression in a population over the age of 60, is a highly debilitating mental health condition with a prevalence of 25% versus 10% in the general population.1, 2 Increasing prevalence is expected in the next 30 years with a rise in the population size for adults over 60 from 12% to 22%.3
- Limiting variables in the treatment of geriatric depression include polypharmacy, intolerable adverse effects, medical comorbidities, drug resistance and atypical symptom presentation.2-7
- Due to uniformity in underlying pathophysiology, current treatment guidelines for geriatric depression are the same as for the general population. …
Perceptions Of Mental Health Among Pakistani Women With Micro-Finance Loans: An Interpretive Descriptive Study,
2023
Brock University
Perceptions Of Mental Health Among Pakistani Women With Micro-Finance Loans: An Interpretive Descriptive Study, Farhana Irfan Madhani, Catherine Tompkins, Susan Jack, Carolyn Byrne
The Qualitative Report
Mental health has gained significant recognition and importance as a crucial aspect of overall well-being. An individual's mental health is influenced by the intersection of individual, social, cultural, and systematic sources of stress and resilience. It is important to include subjective conceptualizations of mental health and well-being to develop culturally sensitive approaches to mental health promotion. This qualitative study aimed to understand how urban-dwelling women living in Pakistan who are micro-finance loan recipients conceptualize the meaning of mental health. Using interpretive description methodology, data were collected and analyzed through in-depth, semi-structured interviews conducted in Urdu with a purposeful sample of …
Evaluating The Feasibility And Impact Of A Well-Being Retreat For Physicians And Advanced Practice Providers,
2023
AdventHealth
Evaluating The Feasibility And Impact Of A Well-Being Retreat For Physicians And Advanced Practice Providers, Amanda K. Bailey, Amanda T. Sawyer, Hong Tao, Leila Durr, Alexandra Lajeunesse, Ravindran Sabapathy, Tyon L. Hall
Journal of Wellness
Introduction: Work stress experienced by physicians and advanced practice providers (APPs) can have a detrimental psychological and physical impact. Targeted interventions that focus on self-awareness, peer connection, and intentional self-care may reduce stress and improve well-being and professional fulfillment.
Methods: This is a summative program evaluation of a two-day well-being retreat for physicians and APPs employed at a healthcare system headquartered in Florida. Led by mental health professionals in May 2022, this retreat combined facilitator-led workshops and experiential practice activities with opportunities for peer connection and designated time with family members. The retreat objectives were to facilitate social …
Improving Minors' Access To Treatment For Opioid Use Disorder: A Policy Analysis,
2023
University of San Francisco
Improving Minors' Access To Treatment For Opioid Use Disorder: A Policy Analysis, Sara Jane Hamilton
Master's Projects and Capstones
As the opioid epidemic continues to have devastating effects on our communities, medications to treat opioid use disorder (MOUDs) are severely underutilized especially for adolescents. Unlike adults, minors need parental approval before obtaining MOUDs presenting a key barrier to timely treatment. Being able to treat adolescents as soon as they are ready is critically important for people with OUD, and while cost and other barriers have been addressed in the literature, there is a paucity on how parental consent affects the accessibility of treatment. This paper aims to explore a potential policy in California that addresses the lack of access …
Impact Of Strokes: The Burden Of Care, Post-Cva Fatigue & Caregiver Role Strain,
2023
University of Texas at Tyler
Impact Of Strokes: The Burden Of Care, Post-Cva Fatigue & Caregiver Role Strain, Tanya G. Schlemmer
Nursing Faculty Publications and Presentations
Strokes and cerebral vascular accidents (CVAs) and related disease events are an unfortunate circumstance that inflicts individuals around the world and impacts people every day as individuals and their caregivers. The consequences of these strokes or CVA events are life-changing for all those involved. As a result of long-term disability related to strokes, the caregiver may undergo many emotional, psychological, and physical factors that impact their daily lives. There is a relatively short period of time to react to the necessary change and as a result there may be differences in coping associated with these unexpected health circumstances. Many stoke …
A.T. Still, School Of Osteopathic Medicine - Volume 1 Issue 1, August 2023 Full Issue,
2023
A.T. Still University
A.T. Still, School Of Osteopathic Medicine - Volume 1 Issue 1, August 2023 Full Issue, Editors ,
Intellectus
No abstract provided.
Breastfeeding Education Of Medical Students And Resident Physicians,
2023
A.T. Still University School of Osteopathic Medicine in Arizona
Breastfeeding Education Of Medical Students And Resident Physicians, Kathleen E.H. Douangchak D.O.
Intellectus
Breastfeeding is widely recognized for its medical and neurodevelopmental benefits, leading to the American Academy of Pediatrics (AAP) recommending exclusive breastfeeding for the first 6 months of an infant’s life with continuation through 2 years of age and beyond.1 However, this literature review finds that despite the 2022 update to the AAP’s recommendations, education on breastfeeding for physicians-in-training is inadequate. Though interventions have been shown to increase the breastfeeding knowledge and confidence of physicians, more research is needed to evaluate the efficacy of educational interventions. This paper emphasizes the urgency of implementing comprehensive interventions that address the gaps in breastfeeding …
Preparing For Pandemics: Lesson Plan Design For Children In Elementary School,
2023
ATSU-SOMA
Preparing For Pandemics: Lesson Plan Design For Children In Elementary School, Daniella Rivera, Enkhtsogt (Steve) Sainbayar, Saleem Choudry, Brittany Vaughn Pierce, Roxana Nouri-Nikbakht, Joy H. Lewis D.O., Phd
Intellectus
Context: The COVID-19 pandemic necessitated distance learning to attenuate the spread of the virus, and school-aged children were particularly affected by this change. Because of their age and education level, children generally lacked understanding about the pandemic and the preventive measures necessary to prevent the spread of this and other infectious diseases. It is unknown how many schools nationwide incorporated disease-prevention education in their curriculums during the pandemic. Therefore, developing distance learning interventions that convey these topics at their level of understanding is important to improve health literacy and raise their awareness of factors that positively influence health.
Objective: To …
Integration Of A Culturally Appropriate Method Of Delivering Health Information In A Non-Clinical Setting,
2023
ATSU-SOMA
Integration Of A Culturally Appropriate Method Of Delivering Health Information In A Non-Clinical Setting, Nancy Nguyen, Merett Saad, Andrew Vo, Alejandro Castaneda, Uriel Martinez, Jonathan Do, Kevin Trembley, Imran Javaid, Hargurbir Alhuwalia, Jaskirat Malhi, Carolina Quezada M.D., Joy H. Lewis D.O., Phd
Intellectus
Context:
A.T. Still University School of Osteopathic Medicine in Arizona (ATSU-SOMA) has an established partnership with Family HealthCare Network (FHCN). Initial meetings with the local community outreach department identified that a substantial majority of the Hispanic population served by this health center may lack access to health education. In particular, Spanish-speaking patients at the health center may face language barriers that impair the transfer of health education between the providers, patients, and their families.
Objective:
The purpose of this study was to provide health educational presentations in Spanish in order to improve health knowledge relating to women’s and children’s health. …
Covid-19 Infection With Severe Hypothermia In A Fully Vaccinated Patient,
2023
A.T. Still University School of Osteopathic Medicine in Arizona
Covid-19 Infection With Severe Hypothermia In A Fully Vaccinated Patient, Kathleen E.H. Douangchak
Intellectus
Hypothermia is an uncommon presentation of COVID-19 infection, typically observed in patients with severe disease prior to the availability of vaccines. However, the occurrence of hypothermia in vaccinated patients with COVID-19 disease has not yet been documented. This case reports a rare presentation of severe hypothermia in a 41-year-old female with COVID-19 disease, who suffered from several comorbidities, including heart failure with preserved ejection fraction, chronic pericardial effusion, nephrotic syndrome, CKD 4, hypertension, type 2 diabetes, thyroid cancer status post-thyroidectomy with resultant postsurgical hypothyroidism, glaucoma, and anemia of chronic disease. Upon presentation, the patient was encephalopathic with hypothermia of 27.2 …
Form, Function, And Meaning Of Hiking In Bipoc Communities,
2023
University of St. Augustine for Health Sciences
Form, Function, And Meaning Of Hiking In Bipoc Communities, Karen Rosales, Karen Park
Summer 2023 Virtual OTD Capstone Symposium
This poster presentation is about understanding the form, function, and meaning for hiking in BIPOC communities. This study used a mixed methods approach to obtain quantitative data through a survey and qualitative data through an interview. Through the use of an Occupational Science approach this study aimed to capture the lived experience of those participating in hiking. Understanding the knowledge of individuals occupations is beneficial for Occupational Therapist when working with versatile populations to understand their motivation and culture.
