Mental and Social Health Commons^™

Life’S Essential 8: Optimizing Health In Older Adults, Manish Kumar, Ariela Orkaby, Caitlan Tighe, Dennis T Villareal, Hayley Billingsley, Michael G Nanna, Min Ji Kwak, Namit Rohant, Shreya Patel, Parag Goyal, Scott Hummel, Christina Al-Malouf, Amie Kolimas, Ashok Krishnaswami, Mike W Rich, James Kirkpatrick, Abdulla A Damluji, George A Kuchel, Daniel E Forman, Karen P Alexander

Faculty, Staff and Student Publications

The population worldwide is getting older as a result of advances in public health, medicine, and technology. Older individuals are living longer with a higher prevalence of subclinical and clinical cardiovascular disease (CVD). In 2010, the American Heart Association introduced a list of key prevention targets, known as "Life's Simple 7" to increase CVD-free survival, longevity, and quality of life. In 2022, sleep health was added to expand the recommendations to "Life's Essential 8" (eat better, be more active, stop smoking, get adequate sleep, manage weight, manage cholesterol, manage blood pressure, and manage diabetes). These prevention targets are intended to …

Safety And Efficacy Of Long-Term Deutetrabenazine Use In Children And Adolescents With Tics Associated With Tourette Syndrome: An Open-Label Extension Study, Joseph Jankovic, Barbara Coffey, Daniel O Claassen, Joohi Jimenez-Shahed, Barry J Gertz, Elizabeth A Garofalo, David A Stamler, Maria Wieman, Juha-Matti Savola, Eran Harary, Jessica Alexander, Hadas Barkay, Mark Forrest Gordon

Faculty, Staff and Students Publications

BACKGROUND: Tourette syndrome (TS) is a neurodevelopmental disorder characterized by motor and phonic tics.

OBJECTIVE: To assess the safety and efficacy of deutetrabenazine (Teva Neuroscience, Inc, Parsippany, NJ), a vesicular monoamine transporter 2 inhibitor, in children and adolescents with TS.

METHODS: Alternatives for Reducing Tics in TS (ARTISTS) open-label extension (OLE) (NCT03567291) was a 54-week, global, phase 3, open-label extension study of deutetrabenazine (6-48 mg daily) conducted May 28, 2018 to April 3, 2020 with a 2-week randomized withdrawal period. Participants (6-16 years of age) had TS and active tics causing distress or impairment. Safety (primary outcome) was assessed by …

Engaging Patients In Opioid Use Disorder Treatment: A Mixed Methods Study Investigating Primary Care Team Perspectives On Approaches, Barriers, And Facilitators, Elizabeth J. Austin, Ulrich Koch, Monica S. Ruiz, Anna D. Ratzliff, Emily C. Williams, Yavar Moghimi

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: Harms from opioid use disorder (OUD) cause significant morbidity and mortality, responsible for over 107,000 overdose-related deaths in 2022 and igniting an urgency to expand access to OUD-related care to new settings such as primary care. A critical element of successful OUD care is engaging patients throughout the OUD care continuum and ongoing retention, yet OUD care engagement rates in outpatient settings are hugely variable, ranging from 4%-70% for initial (14-30 day) treatment engagement, and markedly diminishing over time. The barriers that patients cite to engagement point to the need to deliver more patient-centered OUD care, yet little …

Risk Factors Associated With Occupational Stress Among Malaysian Construction Professionals, Nur Syafiqah Fauzan, Nur Alia Farahanin Mohd Tajuddin, Neroshini Thanarejee, Dayana Hazwani Mohd Suadi Nata, Ezrin Hani Sukadarin, Mirta Widia

Makara Journal of Health Research

Background: Construction industries that focus on project-based nature, pressure, and long hours may lead to job-related stress among workers. In many emerging nations, robust economic growth plans generate occupational depression, anxiety, and stress among construction industry personnel. This study aims to determine the relationship between these items and the risk factors (demographic) among Malaysian construction professionals.

Methods: A cross-sectional study was carried out among 173 Malaysian construction professionals. A DASS-21 questionnaire is used to survey eligible respondents.

Results: Findings show that construction professionals have a high level of stress (54.9%), anxiety (48.5%), and depression (37%). Gender is …

The Prevalence Of Human Papillomavirus Vaccination Among Racial And Ethnic Minority Adolescents During The Covid-19 Pandemic, Chinenye Lynette Ejezie, Lara S Savas, Casey Durand, Ross Shegog, Paula Cuccaro

Faculty, Staff and Student Publications

BACKGROUND: Human papillomavirus (HPV) vaccination among adolescents has steadily improved over the past several years. However, research conducted to determine whether the COVID-19 pandemic disrupted this positive trend in HPV vaccine initiation among racial and ethnic minority adolescents is limited. Therefore, this study was conducted to determine if the COVID-19 pandemic and the resulting changes in the US health-care sector affected the increasing HPV vaccine initiation among non-Hispanic Black and Hispanic adolescents aged 13-17 years.

METHODS: Using a cross-sectional design to examine data from the National Immunization Survey-Teen (2019-2021), logistic regression and moderation analysis were used to model race-specific variations …

Perceived Stress, Severity Of Xerostomia, And Periodontal Status In Undergraduate Dental Students, Engku Ahmad Muzhaffar, Zurairah Berahim, Norsila Abdul Wahab, Norkhafizah Saddki

Journal of Dentistry Indonesia

Dentistry is a highly stressful program; stress is associated with xerostomia and periodontal disease.

Objective: This study aims to investigate the association of perceived stress, severity of xerostomia, and periodontal status in dental students.

Methods: This was a two-phase cross-sectional study of 245 Universiti Sains Malaysia (USM) undergraduate dental students. Phase 1 involved administration of the Perceived Stress Scale (PSS-10) and Summated Xerostomia Inventory (SXI). In phase 2, the Community Periodontal Index (CPI) was performed on 150 students to determine their periodontal status.

Results: Mean PSS-10 and SXI scores were 19.6 (SD 5.47) and 7.9 (SD 2.04), respectively. …

Mental Health And Experiences Of Pregnancy Among Black Women And Birthing People With Type 1 Diabetes (T1d), Madeleine E. Marcus

Doctoral Dissertations

This dissertation explored the potential effects of intersections of oppression (i.e., anti-Black racism, diabetes discrimination, and sexism) on mental health and pregnancy experiences among Black women and birthing people with Type 1 diabetes (T1D). Previous studies about pregnancy and T1D have included mainly white, cisgender women. Three participants qualified for inclusion in the present study and participated in semi-structured interviews, which the researcher analyzed using an interpretative phenomenological analysis (IPA) framework. Participants described feeling uncertain about whether aspects of their pregnancy experiences were related to obstetric and/or medical racism. Similarly, participants sometimes seemed uncertain about how racism may affect their …

Management Of The Left Subclavian Artery During Aortic Arch Replacement Using A Frozen Elephant Trunk Approach: A Review, Vicente Orozco-Sevilla, Joseph S Coselli

Faculty, Staff and Students Publications

The frozen elephant trunk (FET) technique for total aortic arch replacement extends repair into the proximal portion of the descending thoracic aorta. Several techniques and modifications of total arch replacement have been described in the literature, and many of these iterations are related to facilitating the distal anastomosis while preserving flow to the left subclavian artery (LSCA), as well as maintaining posterior circulation of the brain via the vertebral artery, by reducing the circulatory arrest time during reconstruction. Because of the LSCA's posterior and deep anatomic location in the chest, particularly in obese patients, this revascularization is often challenging; additional …

Pimavanserin Treatment Increases Plasma Brain-Derived Neurotrophic Factor Levels In Rats, Ashutosh Tripathi, Henry A Nasrallah, Anilkumar Pillai

Faculty, Staff and Student Publications

BACKGROUND: Pimavanserin, a serotonin 5HT-2A receptor inverse agonist is the first-line, FDA-approved treatment of hallucinations and delusions associated with Parkinson's Disease psychosis (PDP), which occurs in up to 50% of PD patients. The neurobiological mechanism underlying the therapeutic effectiveness of Pimavanserin in PDP remains unknown. Several earlier studies have shown that treatment with 5HT-2A antagonists and other drugs acting on the serotonergic system such as SSRIs increase Brain derived neurotrophic factor (BDNF) levels in rodents. BDNF is synthesized as the precursor proBDNF, that undergoes cleavage intra or extracellularly to produce a mature BDNF (mBDNF) protein. mBDNF is believed to play …

Daily Early-Life Exposures To Diet Soda And Aspartame Are Associated With Autism In Males: A Case-Control Study, Sharon Parten Fowler, David Gimeno Ruiz De Porras, Michael D Swartz, Paula Stigler Granados, Lynne Parsons Heilbrun, Raymond F Palmer

Faculty, Staff and Student Publications

Since its introduction, aspartame-the leading sweetener in U.S. diet sodas (DS)-has been reported to cause neurological problems in some users. In prospective studies, the offspring of mothers who consumed diet sodas/beverages (DSB) daily during pregnancy experienced increased health problems. We hypothesized that gestational/early-life exposure to ≥1 DS/day (DSearly) or equivalent aspartame (ASPearly: ≥177 mg/day) increases autism risk. The case-control Autism Tooth Fairy Study obtained retrospective dietary recalls for DSB and aspartame consumption during pregnancy/breastfeeding from the mothers of 235 offspring with autism spectrum disorder (ASD: cases) and 121 neurotypically developing offspring (controls). The exposure odds ratios (ORs) for DSearly and …

Aggregated Molecular Phenotype Scores: Enhancing Assessment And Visualization Of Mass Spectrometry Imaging Data For Tissue-Based Diagnostics, Jessie R Chappel, Mary E King, Jonathon Fleming, Livia S Eberlin, David M Reif, Erin S Baker

Faculty, Staff and Students Publications

Mass spectrometry imaging (MSI) has gained increasing popularity for tissue-based diagnostics due to its ability to identify and visualize molecular characteristics unique to different phenotypes within heterogeneous samples. Data from MSI experiments are often assessed and visualized using various supervised and unsupervised statistical approaches. However, these approaches tend to fall short in identifying and concisely visualizing subtle, phenotype-relevant molecular changes. To address these shortcomings, we developed aggregated molecular phenotype (AMP) scores. AMP scores are generated using an ensemble machine learning approach to first select features differentiating phenotypes, weight the features using logistic regression, and combine the weights and feature abundances. …

Examining Student Resilience By Observing The Effect Of Social Support And Optimism, Erlina Estiyanti Widuri, Mujidin Mujidin, Husnul Khotimah Rustam, Miftakhur Rohmah, Miftakhur Rohmah

Jurnal Kajian Bimbingan dan Konseling

There are many negative situations that make students depressed and very stressed with their academics. Students who lack endurance need conducive conditions through social support and strong optimism. This study aimed to test the effect of social support and optimism on the resilience of students working on their thesis. The subjects involved were 79 active students of the faculty of psychology. This study was conducted with quantitative methods using three scales: resilience, social support, and optimism. Sampling was performed using the purposive sampling technique, while the analysis employed the multiple linear regression technique. The results of the major hypothesis analysis …

Cognitive-Behavioral Counseling: A Strategy To Overcome Students’ Addiction To Tiktok Through Self-Instruction Method, Fiki Prayogi, Prio Utomo, Siti Zahra Bulantika

Jurnal Kajian Bimbingan dan Konseling

TikTok has influenced the development of student behavior. Therefore, a service strategy is needed to overcome TikTok addiction in students. This study aimed to determine whether there was a decrease in TikTok addiction in students after being given cognitive-behavioral counseling with the self-instruction method. The researchers employed experimental research with one group pretest-posttest designs as the research design. The research samples consisted of 18 students. The researchers utilized the TikTok addiction scale as the research instrument for collecting the data. The validity result of the instrument was in KMO value of 0.791 with Sig. of 0.000 (0.791 greater than 0.5). …

Indonesia And Malaysia Students’ Quality Of Life After The Covid-19 Pandemic: A Mixed Methods Study, Juster Juster Sinaga, Mawaddah Sarif, Siti Aishah Hassan

Jurnal Kajian Bimbingan dan Konseling

Learning from home during the COVID-19 pandemic and learning face-to-face at school with strict health protocols during the COVID-19 pandemic have long-term negative effects on the psychological health of students. This situation may impact life quality (QoL). To measure students’ quality of life, mixed methods were adopted. Participants in this research ranged in age from 12 to 19 years. The study involved a total of 139 research participants. Kidscreen-27 questionnaires with a reliability coefficient of 0.913 percent were used. The interviews were conducted according to a set of defined rules. This data was collected online. The analysis was quantitative, qualitative, …

Analyzing Children’S Trauma During The Covid-19 Pandemic Using Relational-Cultural Theory: A Literature Review, Septinda Rima Dewanti, Yuejiao Wu

Jurnal Kajian Bimbingan dan Konseling

The impact of the Covid-19 pandemic has been extensively discussed, but only a limited number of studies investigate how pandemics are related to traumatic experiences for children. Using a literature review of 38 peer-reviewed articles, both qualitative and quantitative published in the reputable international journals, this study examines how pandemic situations trigger trauma in children. From the literature review, we concluded a number of impacts of Covid 19 on children, including their experience of sudden and shocking changes of events, loss, grief, domestic violence, Covid-19 infections, being surrounded by an adult experiencing mental health disturbance, and becoming the victim of …

Role Of Peer Groups In Career Exploration Of Generation Z In Responding To Work Transitions, Abdul Hadi, Eka Aryani, Palasara Brahmani Laras, Affero Bin Ismail, Affero Bin Ismail

Jurnal Kajian Bimbingan dan Konseling

This research examines the influence of peer groups in determining student career life. By using a quantitative approach, we aim to investigate the role of peer groups in Generation Z’s career exploration to respond to work transitions. The subjects of this study were 72 vocational high school students. Data collection was carried out using the Peer Group and Career Exploration scales which were developed by adapting the Likert scale. Our analysis results suggested that peer groups carry 57 percent effects on the participants’ career exploration of students. In addition, the results of the Pearson correlation test also showed a 0.755 …

Symptoms Of Posttraumatic Stress Disorder In Middle School Students After The Covid-19 Outbreak, Nandang Rusmana, Anne Hafina, Yadi Ruyadi, Lutfi Nur, Lutfi Nur

Jurnal Kajian Bimbingan dan Konseling

COVID-19 bears various traumatic impacts on students. This study aims to identify PTSD symptoms in junior and senior high school students after the COVID-19 outbreak. The study was conducted using a cross-sectional survey method. Meanwhile, the data was collected using a problem checklist instrument. Further, the obtained data were analyzed using non-parametric statistics with the Mann-Whitney test to identify differences in PTSD symptoms based on gender and level of education. The results of the analysis show that symptoms appear in every physical, emotional, mental, behavioral, and spiritual aspect. Besides, we also found a significant difference in the level of anxiety …

Smad8 Is Increased In Duchenne Muscular Dystrophy And Suppresses Mir-1, Mir-133a, And Mir-133b, Meghan L Royle, Eric J Connolly, Sara Nowakowski, Jeff R Temple

Faculty, Staff and Student Publications

OBJECTIVES: Studies are beginning to document an association between sleep duration and a range of adolescent delinquent behaviors, including weapon carrying. However, little is known about whether and to what extent sleep quality - another dimension of sleep for healthy adolescent functioning - is associated with weapon carrying. We address this gap in knowledge by evaluating the role of restless sleep and sleep duration in adolescent weapon carrying.

METHODS: We analyze data from a diverse sample of 994 adolescents from Texas, USA collected in 2010. Multivariate logistic regression models estimate the association of sleep duration and restless sleep on weapon …

Association Between Chronic Disease And Substance Use Among Older Adults In Tennessee, Manik Ahuja, Jessica Stamey, Johanna Cimilluca, Kawther Al Skir, Mary K. Herndon, Kathleen Baggett, Thiveya Sathiyasaleen, Praveen Fernandopulle

ETSU Faculty Works

Background:

Design and methods:

Utilization Of Wellness Practices For Burnout And Stress During Covid-19 Among An Interdisciplinary Cohort Of Emergency Healthcare Workers, Michael J. Zdradzinski, Sheri-Ann O. Kaltiso, Roslyn Seitz, Timothy P. Moran, Jennifer Clements, Sheryl L. Heron, Michelle D. Lall

Journal of Wellness

Introduction: The Coronavirus Disease (COVID-19) introduced additional stress to the baseline occupational stressors of emergency care workers. The objectives of this study were to evaluate perceived stress and burnout and the utilization and perceived benefit of wellness practices among emergency healthcare workers (EHCWs), including: emergency physicians, advanced practice providers (APPs), nurses, and departmental administrative staff during the COVID-19 pandemic.

Methods: A cross-sectional 28-item electronic survey of EHCWs at three hospitals in a major United States city was used to measure participants’ utilization and perceived benefit of wellness practices, burnout (2-item measure), overall stress (perceived stress scale), and stress …