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3,238 full-text articles. Page 144 of 155.

Cyp2d7 Sequence Variation Interferes With Taqman Cyp2d6 (*) 15 And (*) 35 Genotyping., Amanda K. Riffel, Mehdi Dehghani, Toinette Hartshorne, Kristen C. Floyd, J Steven Leeder, Kevin P. Rosenblatt, Andrea Gaedigk 2015 Children's Mercy Hospital

Cyp2d7 Sequence Variation Interferes With Taqman Cyp2d6 (*) 15 And (*) 35 Genotyping., Amanda K. Riffel, Mehdi Dehghani, Toinette Hartshorne, Kristen C. Floyd, J Steven Leeder, Kevin P. Rosenblatt, Andrea Gaedigk

Manuscripts, Articles, Book Chapters and Other Papers

TaqMan™ genotyping assays are widely used to genotype CYP2D6, which encodes a major drug metabolizing enzyme. Assay design for CYP2D6 can be challenging owing to the presence of two pseudogenes, CYP2D7 and CYP2D8, structural and copy number variation and numerous single nucleotide polymorphisms (SNPs) some of which reflect the wild-type sequence of the CYP2D7 pseudogene. The aim of this study was to identify the mechanism causing false-positive CYP2D6 (*) 15 calls and remediate those by redesigning and validating alternative TaqMan genotype assays. Among 13,866 DNA samples genotyped by the CompanionDx® lab on the OpenArray platform, 70 samples were identified as …


The Hare And The Hortoise [Sic]: The Potential Versus The Reality Of Etp Implementation, Kyaw Kyaw Htat, Patricia A. H Williams, Vincent McCauley 2015 Edith Cowan University

The Hare And The Hortoise [Sic]: The Potential Versus The Reality Of Etp Implementation, Kyaw Kyaw Htat, Patricia A. H Williams, Vincent Mccauley

Research outputs 2014 to 2021

In a health system increasingly driven by cost constraints, there is a focus on improved electronic transfer of information to support healthcare delivery. One area of healthcare that has moved more quickly than others to achieve this is prescribing in the primary care environment. Whilst the move to electronic transfer of prescriptions has reduced transcription errors, the regulatory environment persists with handwritten signatures. This constraint, whilst addressed slowly with technology solutions, needs support from legislative change. The ultimate step is to have a secure mobile model, which would support the move to a fully-electronic, paperless transaction model.


Patterns In Chaplain Documentation Of Assessments And Interventions, A Descriptive Study, Kevin E. Adams 2015 Virginia Commonwealth University

Patterns In Chaplain Documentation Of Assessments And Interventions, A Descriptive Study, Kevin E. Adams

Theses and Dissertations

Abstract

PATTERNS IN CHAPLAIN DOCUMENTATION OF ASSESSMENTS AND INTERVENTIONS, A DESCRIPTIVE STUDY

by Kevin Eugene Adams, MDiv

A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University

Virginia Commonwealth University, 2015

Diane Dodd-McCue, D.B.A, Department of Patient Counseling

There is increasing emphasis on the importance of evidence-based care provided by all disciplines in healthcare. The Electronic Health Record (EHR) is becoming the standard for communicating assessments, plans of care, interventions, and outcomes of patient care. The spiritual care literature demonstrates the importance of assessing religious/spiritual needs and resources and developing …


Validity And Usability Of A Professional Association’S Web-Based Knowledge Translation Portal: American Physical Therapy Association’S Ptnow.Org, Judith E. Deutsch, Wendy Romney, Jan Reynolds, Tara Jo Manal 2015 Sacred Heart University

Validity And Usability Of A Professional Association’S Web-Based Knowledge Translation Portal: American Physical Therapy Association’S Ptnow.Org, Judith E. Deutsch, Wendy Romney, Jan Reynolds, Tara Jo Manal

All PTHMS Faculty Publications

Background: PTNow.org is an evidence-based, on-line portal created by a professional membership association to promote use of evidence in practice and to help decrease unwarranted variation in practice. The site contains synthesis documents designed to promote efficient clinical reasoning. These documents were written and peer-reviewed by teams of content experts and master clinicians. The purpose of this paper is to report on the content and construct validity as well as usability of the site. Methods: Physical therapist participants used clinical summaries (available in 3 formats--as a full summary with hyperlinks, "quick takes" with hyperlinks, and a portable two-page version) on …


Missing Photos, Suffering Withdrawal, Or Finding Freedom? How Experiences Of Social Media Non-Use Influence The Likelihood Of Reversion, Eric P.S. Baumer, Shion Guha PhD, Emily Quan, David Mimno, Geri K. Gay 2015 Parkview Health

Missing Photos, Suffering Withdrawal, Or Finding Freedom? How Experiences Of Social Media Non-Use Influence The Likelihood Of Reversion, Eric P.S. Baumer, Shion Guha Phd, Emily Quan, David Mimno, Geri K. Gay

Health Services and Informatics Research

This article examines social media reversion, when a user intentionally ceases using a social media site but then later resumes use of the site. We analyze a convenience sample of survey data from people who volunteered to stay off Facebook for 99 days but, in some cases, returned before that time. We conduct three separate analyses to triangulate on the phenomenon of reversion: simple quantitative predictors of reversion, factor analysis of adjectives used by respondents to describe their experiences of not using Facebook, and statistical topic analysis of free-text responses. Significant factors predicting either increased or decreased likelihood of reversion …


This Digital Life: A Neighborhood-Based Study Of Adolescents' Lives Online, Jessica Pater PhD, Andrew D. Miller, Elizabeth Mynatt 2015 Parkview Health

This Digital Life: A Neighborhood-Based Study Of Adolescents' Lives Online, Jessica Pater Phd, Andrew D. Miller, Elizabeth Mynatt

Health Services and Informatics Research

In Proceedings of the 33rd Annual ACM Conference on Human Factors in Computing Systems.

In this paper, we present the results of a multi-year study of the social computing practices of 179 adolescents (Mage=12.4 years, SD=1.3; range: 10-14) living in a majority-minority lower-income urban neighborhood in the Southeast U.S. We investigate shifting social media practices using annual surveys and focus groups. We describe participants’ social media use and motivations and show how that use has shifted over time. We show how participants identify social pressures and influences as well as specific behaviors including computer-mediated risky behaviors and self-harm. We discuss …


Cybersecurity Vulnerabilities In Medical Devices: A Complex Environment And Multifaceted Problem, Patricia A.H. Williams, Andrew J. Woodward 2015 Edith Cowan University

Cybersecurity Vulnerabilities In Medical Devices: A Complex Environment And Multifaceted Problem, Patricia A.H. Williams, Andrew J. Woodward

Research outputs 2014 to 2021

The increased connectivity to existing computer networks has exposed medical devices to cybersecurity vulnerabilities from which they were previously shielded. For the prevention of cybersecurity incidents, it is important to recognize the complexity of the operational environment as well as to catalog the technical vulnerabilities. Cybersecurity protection is not just a technical issue; it is a richer and more intricate problem to solve. A review of the factors that contribute to such a potentially insecure environment, together with the identification of the vulnerabilities, is important for understanding why these vulnerabilities persist and what the solution space should look like. This …


Research Brief: "The Potential For Health-Related Uses Of Mobile Phones And Internet With Homeless Veterans: Results From A Multisite Survey", Institute for Veterans and Military Families at Syracuse University 2014 Syracuse University

Research Brief: "The Potential For Health-Related Uses Of Mobile Phones And Internet With Homeless Veterans: Results From A Multisite Survey", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the use of mobile phones among homeless veterans for medical appointment reminders, and other health services provided by healthcare practitioners. In policy and practice, social workers and counselors should determine whether mobile communication would benefit homeless veterans with whom they work and should identify certain barriers to mobile communication that could exist; the VA should expand its mobile notification efforts and look for programs that reduce barriers to regular access to mobile communication. Suggestions for future research include expanding the sample of homeless veterans to include those who are living on the streets or in a …


Innovative Workforce Plan: Recently Graduated Nurses As Super Users For Ehr Implementation In A Multi-Hospital Organization, Katherine L. Bullard 2014 University of San Francisco

Innovative Workforce Plan: Recently Graduated Nurses As Super Users For Ehr Implementation In A Multi-Hospital Organization, Katherine L. Bullard

Doctor of Nursing Practice (DNP) Projects

A regional health system’s decision to rapidly implement a new electronic health record (EHR) in order to meet Stage 2 meaningful use requirements led to a need for innovative cost-containment strategies. Tapping the local pool of unemployed newly graduated nurses as half the required super user workforce leveraged the technology skills of novice nurses registered nurses as trainers of experienced nurses in five hospitals. The novel workforce migrated from hospital to hospital, thereby reducing the number of experienced nurses reassigned to super user duties in each hospital. This strategy also reduced the amount of contract labor required to backfill nurse …


Specimen Labeling Improvement Project: Slip, Traci Hoiting 2014 University of California - San Francisco

Specimen Labeling Improvement Project: Slip, Traci Hoiting

Doctor of Nursing Practice (DNP) Projects

Blood specimens are labeled at the time of acquisition in order to identify and match the specimen, label, and order to the patient. While the labeling process is not new, it is frequently laden with errors (Brown, Smith, & Sherfy, 2011). Wrong blood in tube (WBIT) poses significant risk. Multiple factors contribute to mislabeling errors, including lax policies, limited technological solutions, decentralized labeling processes, multi-tasking, distraction from the clinician, and insufficient education and training of staff. To reduce blood specimen labeling errors, a large academic medical center implemented an innovative technological solution for specimen labeling that integrates patient identification, physician …


Implementing And Evaluating A Clinical Information Interface Between An Electronic Medical Record And A Patient Classification System, Tanya Osborne-McKenzie 2014 University of San Francisco

Implementing And Evaluating A Clinical Information Interface Between An Electronic Medical Record And A Patient Classification System, Tanya Osborne-Mckenzie

Doctor of Nursing Practice (DNP) Projects

As a result of the Affordable Care Act and the Institute of Medicine’s initiatives, hospitals are challenged to improve outcomes as efficiently as possible. How does the national initiative of RNs partnering with other healthcare professionals to improve the quality of patient care at a lower cost, cascade down to individual organizations? One answer may come by focusing on nurse staffing in acute care hospitals. Considering the impact RNs have on patient quality outcomes and the bottom line of hospitals, appropriate management of the RN workforce is one of the most important areas hospitals can focus on in order to …


Customising Doctor-Nurse Communications, Brian Cusack, Dave Parry 2014 Auckland University of Technology

Customising Doctor-Nurse Communications, Brian Cusack, Dave Parry

Australian eHealth Informatics and Security Conference

Doctor-Nurse communications are critical for patient safety and workflow effectiveness. Our research question was: What further improvements can be made to current communication systems? A variety of mobile and land based communication systems have been used and experimented with. In the study, the pager was found to be most common and more recent attempts to provide broadband capability with systems such as the iBeep. We built an alternative information system using Android phones and a software application that was customised by feedback from the medical professionals. The trial in five wards with 22 doctors and 170 nurses over one month …


Security Of Electronic Health Records In A Resource Limited Setting: The Case Of Smart-Care Electronic Health Record In Zambia, Keith Mweebo 2014 Edith Cowan University

Security Of Electronic Health Records In A Resource Limited Setting: The Case Of Smart-Care Electronic Health Record In Zambia, Keith Mweebo

Australian eHealth Informatics and Security Conference

This paper presents a case study of security issues related to the operationalization of smart-care, an electronic medical record (EMR) used to manage Human Immunodeficiency Virus (HIV) health information in Zambia. The aim of the smart-care program is to link up services and improve access to health information, by providing a reliable way to collect, store, retrieve and analyse health data in a secure way. As health professionals gain improved access to patient health information electronically, there is need to ensure this information is secured, and that patient privacy and confidentiality is maintained. During the initial stages of the program …


The Potentials And Challenges Of Big Data In Public Health, Rena N. Vithiatharan 2014 Edith Cowan University

The Potentials And Challenges Of Big Data In Public Health, Rena N. Vithiatharan

Australian eHealth Informatics and Security Conference

The potential to use big data sources for public health increases with the broadening availability of data and improved methods of analysis. Whilst there are some well-known examples of the opportunistic use of big data, such as GoogleFlu, public health has not yet realised the full potential of such data sources. A literature review was undertaken to identify the potential of such data collections to impact public health, and to identify what challenges are currently limiting this potential. The potential include improved real-time analysis, research and development and genome studies. However, challenges listed are poor universal standardisation and classification, privacy …


Byod In Ehealth: Herding Cats And Stable Doors, Or A Catastrophe Waiting To Happen?, Krishnun Sansurooh, Patricia A H Williams 2014 Edith Cowan University

Byod In Ehealth: Herding Cats And Stable Doors, Or A Catastrophe Waiting To Happen?, Krishnun Sansurooh, Patricia A H Williams

Australian eHealth Informatics and Security Conference

The use of personal devices in the work environment has crossed the boundaries of work and socially related tasks. With cyber criminals seriously targeting healthcare for medical identity theft, the lack of control of new technologies within healthcare networks becomes an increasing vulnerability. The prolific adoption of personal mobile devices in the healthcare environment requires a proactive approach to the management of Bring Your Own Device (BYOD). This paper analysed the current state of the problem and the challenges that this creates in an environment that has stringent privacy and security requirements. The discourse demonstrates that the issue is not …


3rd Australian Ehealth Informatics And Security Conference, 2014, Edith Cowan University: Conference Details, Security Research Institute, Edith Cowan University 2014 Edith Cowan University

3rd Australian Ehealth Informatics And Security Conference, 2014, Edith Cowan University: Conference Details, Security Research Institute, Edith Cowan University

Australian eHealth Informatics and Security Conference

No abstract provided.


Big Data In Healthcare: What Is It Used For?, Rebecca Hermon, Patricia A H Williams 2014 Edith Cowan University

Big Data In Healthcare: What Is It Used For?, Rebecca Hermon, Patricia A H Williams

Australian eHealth Informatics and Security Conference

Big data analytics is a growth area with the potential to provide useful insight in healthcare. Whilst many dimensions of big data still present issues in its use and adoption, such as managing the volume, variety, velocity, veracity, and value, the accuracy, integrity, and semantic interpretation are of greater concern in clinical application. However, such challenges have not deterred the use and exploration of big data as an evidence source in healthcare. This drives the need to investigate healthcare information to control and reduce the burgeoning cost of healthcare, as well as to seek evidence to improve patient outcomes. Whilst …


Avoiding Epic Fails: Software And Standards Directions To Increase Clinical Safety, Patricia A H Williams, Vincent B. McCauley 2014 Edith Cowan University

Avoiding Epic Fails: Software And Standards Directions To Increase Clinical Safety, Patricia A H Williams, Vincent B. Mccauley

Australian eHealth Informatics and Security Conference

No abstract provided.


Managing Wireless Security Risks In Medical Services, Brian Cusack, Akar Kyaw 2014 Auckland University of Technology

Managing Wireless Security Risks In Medical Services, Brian Cusack, Akar Kyaw

Australian eHealth Informatics and Security Conference

Medical systems are designed for a range of end users from different professional skill groups and people who carry the devices in and on their bodies. Open, accurate, and efficient communication is the priority for medical systems and consequently strong protection costs are traded against the utility benefits for open systems. In this paper we assess the vulnerabilities created by the professional and end user expectations, and theorise ways to mitigate wireless security vulnerabilities. The benefits of wireless medical services are great in terms of efficiencies, mobility, and information management. These benefits may be realised by treating the vulnerabilities and …


H.E.A.P.S. In Advances Towards A Healthier Samoa The Health Education And Promotions Section’S Role In Combating Non-Communicable Diseases, Kara Le 2014 SIT Study Abroad

H.E.A.P.S. In Advances Towards A Healthier Samoa The Health Education And Promotions Section’S Role In Combating Non-Communicable Diseases, Kara Le

Independent Study Project (ISP) Collection

With an increase in the number of health issues within Samoa, specifically in relation to non-communicable diseases (NCDs), it is important to examine the efforts being made by government health officials to improve Samoa’s overall health status. This study explores the role of the Health Education and Promotion Section (H.E.A.P.S.) of the Ministry of Health in establishing and promoting healthier standards within the Samoan community. The current efforts of H.E.A.P.S. in combating NCDs through recently introduced projects and programs were explored in-depth. Further analysis of the design and effectiveness of these programs in changing the unhealthy habits of Samoan people …


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