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A Comparison Of Qualitative And Quantitative White Matter Methods In Pediatric Traumatic Brain Injury, Kacie Larae Wright
A Comparison Of Qualitative And Quantitative White Matter Methods In Pediatric Traumatic Brain Injury, Kacie Larae Wright
Theses and Dissertations
Magnetic resonance imaging is used to assess white matter (WM) abnormalities including total WM volumes and WM hyperintensities (WMHs). Comparisons between several qualitative and quantitative methods to assess WM that are used in research and clinical settings are lacking in pediatric traumatic brain injury (TBI). This study 1) WM methods including Scheltens ratings, manual tracings, NeuroQuant®, and FreeSurfer; (2) compared total WM volumes and WMHs to assess potentially similar reporting of WM integrity; and (3) assessed the relationship between cognitive functions (intelligence, attention, processing speed, and language) and WM in pediatric TBI.Sixty participants (65% male) between ages 8-13 years old, …