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Autism Spectrum Disorder

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Identifying Cognitive Profiles In Children With Neurodevelopmental Disorders Using Online Cognitive Testing, Abagail Hennessy Jun 2023

Identifying Cognitive Profiles In Children With Neurodevelopmental Disorders Using Online Cognitive Testing, Abagail Hennessy

Electronic Thesis and Dissertation Repository

Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), are characterized by diverse cognitive deficits. Early identification of cognitive deficits is fundamental to improving academic and emotional/behavioural outcomes in children. Creyos has pioneered online cognitive testing which assesses working memory, attention, reasoning and verbal abilities. We developed audiovisual instructions for the task battery and implemented them in an online sample of children ages 4-16 with ADHD (n = 83), ASD (n = 37), and typically developing children (TD) (n = 86), to determine whether unique cognitive profiles would emerge. Four tasks reflective of working memory, …


Early Gaze Behaviours In Infants At High Familial Risk For Autism Spectrum Disorder: Association With Brain Development, Julia Teixeira Pinto Montenegro May 2022

Early Gaze Behaviours In Infants At High Familial Risk For Autism Spectrum Disorder: Association With Brain Development, Julia Teixeira Pinto Montenegro

Electronic Thesis and Dissertation Repository

Children diagnosed with Autism Spectrum Disorder (ASD) show impairments in gaze-following and will seldom engage in joint attention (JA). The ability to initiate JA (IJA) can be more impaired than the ability to respond to JA (RJA). In a longitudinal study, 101 high-risk infants for ASD (62% males) completed MRI scans at 4 or 6 months of age. Subcortical volumes (thalamus, basal ganglia, hippocampus, amygdala) were extracted. Gaze and JA behaviours were assessed with standardized measures. The majority of infants were IJA non-responders (n=93, 92%), and over half were RJA non-responders (n=50, 52%). In the non-responder groups, models testing the …


Early Adversity And Positive Parenting: Predicting Executive Functioning In Children With Asd, Elizabeth A. Kuenzel Apr 2021

Early Adversity And Positive Parenting: Predicting Executive Functioning In Children With Asd, Elizabeth A. Kuenzel

Electronic Thesis and Dissertation Repository

Children with Autism Spectrum Disorder (ASD) are statistically more likely to experience early adversity; however, little is known about which types of adversity are most prevalent, the role of parenting as a protective factor, and how this early life stress impacts cognitive outcomes. We assessed adversity and parenting styles in 238 children (ASD=82) aged 6–16 years using parent report. Intellectual abilities were assessed using the WISC-V. Children with ASD had increased incidence of familial stressors compared to Typically Developing (TD) children. Positive parenting was associated with significant decreases in familial adversity for all children. Environmental stressors were associated with cognitive …