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Early Gaze Behaviours In Infants At High Familial Risk For Autism Spectrum Disorder: Association With Brain Development, Julia Teixeira Pinto Montenegro
Early Gaze Behaviours In Infants At High Familial Risk For Autism Spectrum Disorder: Association With Brain Development, Julia Teixeira Pinto Montenegro
Electronic Thesis and Dissertation Repository
Children diagnosed with Autism Spectrum Disorder (ASD) show impairments in gaze-following and will seldom engage in joint attention (JA). The ability to initiate JA (IJA) can be more impaired than the ability to respond to JA (RJA). In a longitudinal study, 101 high-risk infants for ASD (62% males) completed MRI scans at 4 or 6 months of age. Subcortical volumes (thalamus, basal ganglia, hippocampus, amygdala) were extracted. Gaze and JA behaviours were assessed with standardized measures. The majority of infants were IJA non-responders (n=93, 92%), and over half were RJA non-responders (n=50, 52%). In the non-responder groups, models testing the …