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Experimental Analysis of Behavior Commons™
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Full-Text Articles in Experimental Analysis of Behavior
Assessment Of Sex Differences And Amphetamine On Schedule-Induced Polydipsia, Min Park
Assessment Of Sex Differences And Amphetamine On Schedule-Induced Polydipsia, Min Park
All NMU Master's Theses
Amphetamine (AMPH) is one of the most common psychotropic drugs abused in the United States. Its major pharmacological effect is to increase synaptic dopamine levels in the mesolimbic reward pathway, which in turn causes behavioral effects in animals, and subjective effects in humans. These reinforcing properties of AMPH trigger very strong levels of craving the drug, and eventually result in patterns of compulsive use of AMPH. Regarding psychostimulant action, female rats have been reported to be more vulnerable to the reinforcing effects of psychostimulants. In the current study, schedule-induced polydipsia (SIP), an animal model of compulsive behavior, was applied for …
Behavioral Impairment Following Gestational Exposure To Titanium Dioxide Nanomaterial Aerosols In Male And Female Rats, Matthew Leland Eckard
Behavioral Impairment Following Gestational Exposure To Titanium Dioxide Nanomaterial Aerosols In Male And Female Rats, Matthew Leland Eckard
Graduate Theses, Dissertations, and Problem Reports
Engineered nanomaterials (ENMs) are beginning to be recognized as hazardous to human and animal health. Titanium dioxide (TiO2) is primarily used as a whitening agent in paints, plastics, and sunscreens. While relatively inert in its bulk form, nano-TiO2 (diameter) can produce prolonged inflammation and oxidative stress in target tissue. Recently, the potential for nano-TiO2 to cause neuroinflammation and damage has heightened concerns about its continued use. One important concern is that nano-TiO2, and other metal oxide ENMs, may affect fetal neurodevelopment. Accordingly, it is imperative to screen ENMs, like TiO2, for possible neurotoxicity following developmental exposures. The current set of …