Alterations To Taste Preference In Mc4r Haploinsufficiency Manifest Prior To Dietary Induced Obesity And Are Accompanied By Dendritic Spine Alterations To Medium Spiny Neurons Of The Nucleus Accumbens In Adulthood, Robert Francis Roscoe Jr.

Theses and Dissertations

Obesity has reached epidemic proportions in the United States and has become an increasing public health concern for developed nations. Haploinsufficiency of melanocortin receptor 4 has been identified as the single most common monogenetic cause of obesity in humans. Using the MC4R +/- haploinsufficient rat, we sought to determine potential alterations in body weight and morphology, locomotor activity, sucrose concentration preference, and progressive-ratio operant testing in a dietary-induced obesity environment. Rats were placed on four separate diets corresponding to 1.7% saturated fat with 12.2% total kcal/fat, 6% saturated fat with a 40% total kcal/fat, 12% saturated fat with a 40% …

A Preliminary Study Of Distracted Driving, Sarina Karwande, Ashley Nieto, Lauren Rhodes

Student Scholar Symposium Abstracts and Posters

The Centers for Disease Control (CDC) report distracted driving is a “problem on the rise” with increasing numbers injuries and deaths each year. More than 9 people are killed each day while more than 1,153 people are injured in crashes involving a distracted driver. Specifically, the number one killer of adolescents (ages 15-24) is automobile related deaths due to distracted driving. One of the most dangerous forms of distracted driving is texting while driving because it combines all three types of distraction: visual, manual, and cognitive. Texting and driving is a growing public safety hazard as seen through media and …

Hemispheric Bases For Emotion And Memory, Tad T. Brunyé, Sarah R. Cavanagh, Ruth E. Propper

Department of Psychology Faculty Scholarship and Creative Works

The goal of this Research Topic was to bring together diverse scientific perspectives on lateralized brain mechanisms underlying emotion, motivation, and memory. The Topic resulted in eight articles, three of which report original research and five of which review and synthesize past research with the aim of developing new hypotheses and theory. A range of international experts with diverse backgrounds, theoretical perspectives, and experimental methods contributed to the Topic. Contributions strongly reflect this diversity, ranging from examining pupil dilation in response to viewing Rembrandt portraits to understanding how caffeine supplementation influences levels of spatial processing. In all cases, the authors …

A Quantitative Analysis Of The Value-Enhancing Effects Of Nicotine, Bupropion, And Varenicline In Male And Female Rats, Scott Barrett

Department of Psychology: Dissertations, Theses, and Student Research

Smoking and tobacco dependence are serious health concerns in the United States and globally. Reward via the pharmacological effects of nicotine are believed to be the principal motivating factor that drive tobacco dependence. Research reveals differences in sensitivity between males and females to the motivational effects of nicotine in tobacco use. Enhancement of reinforcement value of non-nicotine rewards contributes to overall nicotine reward. Similar value-enhancing effects have been observed by the two most commonly prescribed smoking cessation aids, bupropion and varenicline. The present dissertation investigated the value-enhancing effects of nicotine, bupropion and varenicline in both male and female rats using …

Factors That Affect Attachment Between The Employed Mother And The Child, Infancy To Two Years, Naureen Kassamali, Salma Amin Rattani

School of Nursing & Midwifery

To explore a mother's feeling of attachment and the affects her working status on the attachment relationship with her child, upon ethical clearance from the institutional ethics committee, in-depth interviews of nine participants were conducted. Mothers enrolled were those who resumed the employment within the first year of post-delivery and were having a child up to two years of age. Results revealed that maternal employment itself does not enhance or deteriorate attachment with the child. It is combinations of factors that revolve around it impact on their bond. Overall, maternal integration or the balance of the dual roles of employment …

The Neurobehavioral Consequences Of Gestational And Chronic Atrazine Exposure In Male And Female Sprague Dawley Rats, Jennifer L. Walters

Dissertations

The adverse health risks of exposure to the herbicide, atrazine, in humans are not fully understood. Although numerous studies have demonstrated atrazine to be an endocrine disrupter, the neurobehavioral consequences of atrazine exposure have not been thoroughly examined. The aim of this study was to investigate the effects of environmentally-relevant levels

of gestational followed by continued chronic atrazine exposure on motor function, learning and memory, anxiety, and striatal dopamine content in rodents. Pregnant Sprague Dawley rats were treated by gavage with 100 µg/kg atrazine (ATZ low), 10 me/kg atrazine (ATZ high), or vehicle on

gestational day l through postnatal day …

The Effect Of Grapes In Mice With Alzheimer's Disease And Brain Injury, Nikita Mistry

Loma Linda University Electronic Theses, Dissertations & Projects

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder resulting in cognitive and memory deficits and deposits of amyloid beta (Aβ) in the cortex and hippocampus are thought to be significant contributors to the disease process. Increasing evidence suggests that foods rich in polyphenols, such as pomegranates and grapes, may have neuroprotective effects in both rodents and humans. Our previous research has shown that a pomegranate-enriched diet decreased Aβ plaque load and improved behavior in Tg2576 mice. In this study, we determined whether a grape-enriched diet altered Aβ neuropathology and TBI in PSAPP mice. Mice received either craniotomy or a moderate …

An Attempt To Establish Approval As A Learned Reinforcer, Kelly T. Kohler

Dissertations

Approval does not function as a powerful reinforcer for many children with autism, making it difficult to reinforce appropriate behavior in a functional and consistent manner. The current study first assessed the effects of establishing approval (“Nice,” accompanied by a smile and nod) and nonsense words as discriminative stimuli, with the intent that they might also become learned reinforcers. We conducted several experiments to assess the effectiveness of approval as a reinforcer, including tests on learning new responses (receptive, expressive, freeoperant, and simple simultaneous discriminations) and tests on the performance of previously mastered responses (receptive and expressive responses). Despite the …

The Use Of Response Interruption Redirection, Timeout, And Differential Reinforoement To Decrease Stereotypy, Jessica Korneder

Dissertations

Behaviors such as toe walking, hand flapping, nonfunctional vocalizations, and rocking are all examples of stereotypy. Stereotypy can occur at high rates in children with and without developmental delays (Smith & Van Houten, 1996). These behaviors can interfere with the acquisition of new skills (e.g., Dunlap, Dyer, & Koegel, 1983; Morrison & Rosales-Ruiz, 1997) and social interactions (Jones, Wint, & Ellis, 1990). The purpose of this study was to assess the effectiveness of response interruption and redirection (RIRD), time-out, and differential reinforcement of other behavior (DRO) in reducing vocal and motor stereotypy with children who engage in automatically reinforced high-rates …

Evaluation Of Novel Κappa Opioid Agonists Alone And In Combination With D-Amphetamine On Locomotor Activity In Sprague-Dawley Rats Evaluation Of Novel Κappa Opioid Agonists Alone And In Combination With D-Amphetamine On Locomotor Activity In Sprague-Dawley Rats, Mary Melissa Peet

Dissertations

Stimulant abuse is a widespread problem that often leads to detrimental health and social consequences. Currently, there are no FDA-approved pharmacotherapies available as a treatment option for stimulant abuse or the prevention of relapse. Drugs targeting kappa opioid receptors (KOR) are under investigation as a potential pharmacotherapy. KOR agonists have been shown to modulate dopamine levels within brain reward pathways, thereby producing anti-addictive effects. Traditional KOR agonists unfortunately tend to produce untoward side effects, including sedation, limiting their therapeutic utility. Structurally different from traditional KOR agonists, salvinorin A (salvA) may produce less sedating effects while still exerting anti-addictive properties. SalvA …

Effects Of Oxytocin On Human Aggression, Joseph L. Alcorn Iii

Dissertations and Theses (Open Access)

EFFECTS OF OXYTOCIN ON HUMAN AGGRESSION

Joseph Louis Alcorn III, B.S.

Advisory Professor: Scott D. Lane, Ph.D.

Human interaction is comprised of common, yet complex, behaviors and the outcomes of these social behaviors can beneficially or detrimentally impact individual and public health. One social behavior that can have profound detrimental outcomes is aggression. Aggression is a class of social behavior that is particularly prevalent in individuals with antisocial personality disorder (ASPD) and comorbid substance use disorder (SUD). Aggression in these individuals can manifest at maladaptive levels that place considerable burdens on public health and communities. Therefore, understanding the neurobehavioral underpinnings …

Change Detection In Rhesus Monkeys And Humans, Deepna T. Devkar, Deepna T. Devkar

Dissertations and Theses (Open Access)

Visual working memory (VWM) is the temporary retention of visual information and a key component of cognitive processing. The classical paradigm for studying VWM and its encoding limitations has been change detection. Early work focused on how many items could be stored in VWM, leading to the popular theory that humans could remember no more than 4±1 items. More recently, proposals have suggested that VWM is a noisy, continuous resource distributed across virtually all items in the visual field, resulting in diminished memory quality rather than limited quantity. This debate about the nature of VWM has predominantly been studied with …

On Reporting The Onset Of The Intention To Move, Uri Maoz, Liad Mudrik, Ram Rivlin, Ian Ross, Adam Mamelak, Gideon Yaffe

Psychology Faculty Books and Book Chapters

"In 1965, Hans Kornhuber and Luder Deecke made a discovery that greatly influenced the study of voluntary action. Using electroencephalography (EEG), they showed that when aligning some tens of trials to movement onset and averaging, a slowly decreasing electrical potential emerges over central regions of the brain. It starts 1 second ( s) or so before the onset of the voluntary action1 and continues until shortly after the action begins. They termed this the Bereitschaftspotential, or readiness potential (RP; Kornhuber & Deecke, 1965).2 This became the first well-established neural marker of voluntary action. In that, the RP allowed for more …

East Asian Low Marriage And Birth Rates: The Role Of Social Status Affordance In Marriage And Childbearing Behavior, Jose C. Yong

Dissertations and Theses Collection (Open Access)

Although declines in marriage and birth rates are generally associated with industrialization and economic advancement, countries with a dominantly East Asian cultural population exhibit the lowest marriage and birth rates in the developed world. This study aims to identify and verify a new latent construct, social status affordance, as an underlying account for the differences in long-term mating outcomes (i.e., marriage and childbearing) between developed East Asian countries and other developed countries. Drawing on an understanding of the specific East Asian cultural values of harmony and deference and, subsequently, the importance of social status conferred by educational and occupational prestige …

Adolescent Bisphenol-A Exposure Decreases Dendritic Spine Density: Role Of Sex And Age, Rachel E. Bowman, Victoria N. Luine, Hameda Khandaker, Joseph J. Villafane, Maya Frankfurt

Psychology Faculty Publications

Bisphenol-A (BPA), a common environmental endocrine disruptor, modulates estrogenic, androgenic, and anti-androgenic effects throughout the lifespan. We recently showed that low dose BPA exposure during adolescence increases anxiety and impairs spatial memory independent of sex. In the current study, six week old Sprague Dawley rats (n=24 males, n=24 females) received daily subcutaneous injections (40 µg/kg bodyweight) of BPA or vehicle for one week. Serum corticosterone levels in response to a 1 h restraint stress and spine density were examined at age 7 (cohort 1) and 11 (cohort 2) weeks. Adolescent BPA exposure did not alter stress dependent corticosterone responses but …

Ua66 Ogden College Of Science & Engineering Newsletter, Cheryl Stevens, Dean

Ogden College of Science & Engineering Publications

No abstract provided.

Directed Forgetting Of Happy And Angry Faces: The Effects Of Facial Emotion And Sex On Recognition Memory For Facial Identity, Kay Chai Tay

Dissertations and Theses Collection (Open Access)

The literature on directed forgetting – which refers to forgetting the specified information intentionally – has almost exclusively focused on either emotional words or pictures. Consequently, little is known about the impact of facial stimuli that demand more complex cognitive processing than words or pictures. A pilot study was conducted to obtain norm ratings on 152 facial images portraying neutral, happy and angry emotions. From this set of facial stimuli, 96 faces were selected for the main study. In the main study, 75 female participants were presented with 48 faces individually with equal number of happy and angry and, male …

Every Breath You Take: An Examination Of The Natural Phenomenon Of Stalking, Gordon A. Crews, Sara K. Green, Paige A. Heinrich

Criminal Justice Faculty Research

Everyone is a potential stalker, given the right set of circumstances. There are a vast number of tools readily available—from social media networking to easily accessible websites that provide background checks for a minimal fee—that allow individuals to observe the life (or lives) of whomever they so desire. But what are the innate, essential traits and characteristics of an individual that extends beyond the more normative expression of romantic interest and the general curiosity that is a natural and accepted occurrence for anyone who has ever been infatuated with another? This paper will consider the intentionality and motivation behind stalking, …

A Transdiagnostic Social Skills Intervention: Using A Structured Story To Teach Children How To Ask A Friend To Play, Elizabeth Santy

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

An (independent samples comparison) controlled study was conducted to assess the efficacy of a novel approach to social skills training for children in a local socialization group at Knippenberg, Patterson & Associates (KPA). The treatment condition involved the combination of a Structured Story (i.e., novel bibliotherapy technique for children with social skills deficits), and a behavioral rehearsal (or role-play) segment, where the children practiced the target social skill featured in the Structure Story. The control group did not receive the Structured Story nor the behavioral rehearsal. Children in both groups engaged in ten-minutes of free play that was videorecorded for …

Using The R-Pas' Aggressive Content Score For The Evaluation Of Aggressive Behaviors In Children, Rebecca Dehass

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The Rorschach Performance Assessment System (R-PAS) was developed in 2011 as an alternative to the previous Comprehensive System. The goal was to improve the psychometrics, and particularly the validity, of this assessment method. The norms for children were questionable in the Comprehensive system (e.g., outdated, low numbers of subjects) and validity studies for children were sparse. One of the indicators included in the R-PAS system, the aggressive content indicator (AgC), is intended to reflect aggressive behavior, but few studies have examined the validity of this indicator. This study examined the validity of AgC in a sample of 32 children and …

A Comparison Of Risk-Taking Measures, Brittany Lang

Journal of Undergraduate Research at Minnesota State University, Mankato

Risk-taking is an important construct that correlates with many areas of study such as substance abuse, psychological disorders, life-span changes and military involvement. As risk- taking is such a broadly defined construct, there are many different means used to measure it. Ironically, there has never been a study done to see whether or not these measures are looking at the same type of risk-taking. Our study investigated the differences and similarities in three risk- taking measures, the Balloon Analogue Risk-Task (BART), the TCU Self-Rating Form and the Domain-Specific Risk-Taking scale (DOSPERT). We analyzed the results within each participant to see …

The Effects Of Varying Duration Of Reinforcement On Novel Selection-Based Mands Versus Topgraphy-Based Mands, Nicholas S. Acker

Masters Theses

In recent years, researchers have evaluated individuals' preferences for different mand modalities and its effects on the acquisition of novel mands during functional con1munication training (i.e., FCT; e.g., Falcomata, Ringdahl, Christensen, & Boelter, 20 I 0). In many of these studies, the modality of responding that Michael ( 1985) classified as selection-based responding, is preferred by participants (e.g., Falcomata et al., 201 0). Wraikat, Sundberg, and Michael (1991) suggest that topography-based responses may be preferable for the acquisition of complex language. However, selection-based verbal responses may have faster acquisition in learning initial verbal operants (Charlop-Christy, Carpenter, Le, LeBlanc & Kellet, …

Generalization Of Fear Effects In Reinstatement To A Discrete Stimulus, Lauren Best

USC Aiken Psychology Theses

The purpose of this study was to investigate generalization of reinstated fear effects to a discrete stimulus. McAllister and McAllister (2006) reported that reinstated fear could generalize over time to similar contexts. The present study aimed to determine if reinstated fear could generalize to similar or different stimuli than conditioning after a long delay between reinstatement and testing. Rat subjects were randomly assigned to six groups (n = 10) which received conditioning and extinction to a 3000 Hz tone. Reinstatement conditioning was then conducted with either the same, similar, or different CS as used in conditioning. Testing for reinstated fear …

A Comparison Of Two Variations Of A Stimulus-Stimulus Pairing Procedure On Novel And Infrequent Vocalizations Of Children With Autism, Andrew J. Bulla

Masters Theses

Despite the growth in a behavioral technology for the treatment of autism, a small population of individuals with autism fails to develop functional language. One procedure used for inducing vocalizations in non-verbal children is a stimulus-stimulus pairing (SSP) procedure. In an SSP procedure a vocalization is paired with a reinforcer over a period of time to establish the vocalization as a learned reinforcer, and any utterance of the target vocalization is believed to be automatically reinforced thus increasing the frequency of the vocalization. Past research has yielded mixed results with the SSP procedure, and more research is warranted to identify …

Tall Tales: Editing Autobiographical Memories, Holly Elizabeth Cole

Graduate Theses and Dissertations

The impact of exaggerating when sharing an autobiographical memory with another person was investigated. Literature indicates that sharing an autobiographical memory serves a social function. However no research has investigated the impact that exaggerating when sharing specific memories has on this function. Research on lying suggests that deviating from the truth would cause the listener to like the speaker less. Research on what makes a good story indicates deviating from the truth could enhance the social benefits of sharing specific autobiographical memories by increasing the quality of the story. In Study 1, participants read scenarios of a person telling a …

The Perception Of Distance On A Real Geographic Slope, David Alan Bunch

Dissertations

Ooi, Wu, and He (2001) have shown that for objects resting on flat, horizontal surfaces, those that appear in the lower sector of the visual field are perceived as close to the observer and objects located near the visual horizon are perceived as further from the observer. Researchers have hypothesized that observers utilize the angle subtended between the horizon and the line of sight to the target object as information for distance.In a previous investigation Hajnal, Bunch, and Kelty-Stephen (2014) showed that an object’s physical angle of declination below the horizon is not uniquely utilized when making distance estimates to …

The Impact Of Sleep Restriction (Nap Deprivation) On Preschool Children's (Aged 3-5) Emotional Response, Hui-Ya Gail Han

Dissertations

This study examined the effect of nap restriction on 3- to 5-year-old habitually napping children’s emotional responding. It was predicted that the intensity of emotional stimuli would moderate the relationship between nap restriction and the magnitude of emotional responding. Specifically, following nap restriction, the emotional responses to stronger stimuli would be amplified, while the emotional responses to weaker stimuli would be reduced. Emotional stimuli, were classified into four categories: strong negative, weak negative, weak positive, and strong positive. Facial electromyography was measured to reflect preschoolers’ emotional responses. The results indicated emotional responses to both strong negative and positive stimuli were …

Effects Of Animal Management Changes On The Activity Budgets And Walking Rates Of Zoo Elephants, Angela Dawn Mackey

Dissertations

The current study aimed to assess the effects of two management strategies, weekly rototilling of the enclosure and the provision of unpredictable foraging opportunities, on the daily behavior of six elephants housed at the San Diego Zoo. Observations took place from January to June 2013 and were conducted throughout a 24- hour period. The study was divided into three phases, each two months in duration. During the first phase (baseline) no changes were made to the current management routine of the elephants. In Phase 2, rototilling of the elephant enclosures was increased from once monthly to once per week, while …

Implicit Theories Of Intelligence And Learning A Novel Mathematics Task, Nathan Oehme Rudig

UNLV Theses, Dissertations, Professional Papers, and Capstones

The social-cognitive model of motivation states that students adopt a theory of the nature of intelligence that guides their goals in academia and their responses to academic setbacks. Students who believe intelligence is an unchanging entity within them are more likely to adopt goals to display high ability, hide low ability, and respond helplessly to failed schoolwork. Conversely, a student who believes intelligence is a measure of effort and persistence will be motivated to gather knowledge and acquire new skills. The current study investigated the role theories of intelligence play in the field of mathematics understanding. In two experiments, participants …

Environmental Context And Aggression: An Experimental Demonstration Of The Role Of Alcohol Expectancies, Brynn E. Sheehan

Psychology Theses & Dissertations

Research has extensively investigated predictors of alcohol-related aggression. Alcohol expectancy theory suggests that the link between alcohol and aggression may be related to one's beliefs regarding the expected effects of alcohol on aggression. As such, research has found that exposure to a bar environment may elicit alcohol-related aggression expectancies (Wall, McKee, & Hinson, 2000; Wall, McKee, Hinson, & Goldstein, 2001). Additionally, aggression expectancies have shown to predict direct aggression, such as hitting or yelling (Leonard, Collins, & Quigley, 2003; Smucker Barnwell, Borders, & Earlywine, 2006). While these research studies have shown separately that alcohol cues elicit aggression expectancies, and that …