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Full-Text Articles in Experimental Analysis of Behavior
Behavioral Economic Demand: Investigation Of Sex Differences In Four Core Genotype Model Of Oral Oxycodone Self-Administration, Michelle Elsmore, David Jentsch, Joshua Peck, Anushree Karkhanis
Behavioral Economic Demand: Investigation Of Sex Differences In Four Core Genotype Model Of Oral Oxycodone Self-Administration, Michelle Elsmore, David Jentsch, Joshua Peck, Anushree Karkhanis
Undergraduate Honors Theses
Opioid misuse has been identified to be related to problematic release of dopamine in the brain that is otherwise satiated by other alternative rewards. As mediated by patterns of positive and negative reinforcement, prolonged opioid use may transition into misuse and development of opioid use disorder. In human populations, men and women differ in their acquisition of drug use and escalation to drug misuse. Women quickly surpass their male counterparts in their transition from use to misuse in what is coined the telescoping effect. In this four core genotype model of oral oxycodone self administration, males were hypothesized to consume …
The Differential Effects Of Acoustic Discriminations On Operant Learning Performance And Neurogenesis In Male And Female Zebra Finches, Kristena L. Newman
The Differential Effects Of Acoustic Discriminations On Operant Learning Performance And Neurogenesis In Male And Female Zebra Finches, Kristena L. Newman
Dissertations, Theses, and Capstone Projects
Adult neurogenesis, the creation of new neurons, occurs throughout the lifespan in most organisms. However, though neuronal proliferation occurs daily, most of these neurons do not survive to become incorporated into preexisting neural circuitry and become fully functioning neurons. In the mammalian brain, adult neurogenesis occurs within the hippocampus, a brain region known to be important in learning and memory. In rats, successful acquisition of certain learning tasks increased new neuron numbers when the learning was sufficiently challenging (Curlik and Shors, 2011). It has also been demonstrated that a spatial discrimination task requires new neurons when the discrimination is more …
Assessing Sex Differences In The Effects Of Short-Term Rem Sleep On Anxiety- And Depressive-Like Behaviors In Rats, Nadia Meshkati
Assessing Sex Differences In The Effects Of Short-Term Rem Sleep On Anxiety- And Depressive-Like Behaviors In Rats, Nadia Meshkati
Seton Hall University Dissertations and Theses (ETDs)
Findings from both human and animal studies suggest rapid eye movement (REM) sleep disturbances following a traumatic event can lead to inability to extinguish the fear association, and eventually influence the development of post-traumatic stress disorder (PTSD). Additionally, research has demonstrated that sleep disruptions, including REM sleep deprivation (RSD), increases anxiety- and depressive-like behaviors and states in animals and people, with evidence of sex differences. Furthermore, it has yet to be determined whether short-term RSD, a more natural animal model of PTSD, can influence affective state of subjects. The present study applied short-term RSD to investigate sex differences in the …
Assessment Of Sex Differences And Amphetamine On Schedule-Induced Polydipsia, Min Park
Assessment Of Sex Differences And Amphetamine On Schedule-Induced Polydipsia, Min Park
All NMU Master's Theses
Amphetamine (AMPH) is one of the most common psychotropic drugs abused in the United States. Its major pharmacological effect is to increase synaptic dopamine levels in the mesolimbic reward pathway, which in turn causes behavioral effects in animals, and subjective effects in humans. These reinforcing properties of AMPH trigger very strong levels of craving the drug, and eventually result in patterns of compulsive use of AMPH. Regarding psychostimulant action, female rats have been reported to be more vulnerable to the reinforcing effects of psychostimulants. In the current study, schedule-induced polydipsia (SIP), an animal model of compulsive behavior, was applied for …
Behavioral Impairment Following Gestational Exposure To Titanium Dioxide Nanomaterial Aerosols In Male And Female Rats, Matthew Leland Eckard
Behavioral Impairment Following Gestational Exposure To Titanium Dioxide Nanomaterial Aerosols In Male And Female Rats, Matthew Leland Eckard
Graduate Theses, Dissertations, and Problem Reports
Engineered nanomaterials (ENMs) are beginning to be recognized as hazardous to human and animal health. Titanium dioxide (TiO2) is primarily used as a whitening agent in paints, plastics, and sunscreens. While relatively inert in its bulk form, nano-TiO2 (diameter) can produce prolonged inflammation and oxidative stress in target tissue. Recently, the potential for nano-TiO2 to cause neuroinflammation and damage has heightened concerns about its continued use. One important concern is that nano-TiO2, and other metal oxide ENMs, may affect fetal neurodevelopment. Accordingly, it is imperative to screen ENMs, like TiO2, for possible neurotoxicity following developmental exposures. The current set of …
Examining The Roles Of Sex, Methamphetamine, And Degree Of Training In Habit Formation In Rats, Hannah Schoenberg
Examining The Roles Of Sex, Methamphetamine, And Degree Of Training In Habit Formation In Rats, Hannah Schoenberg
Graduate College Dissertations and Theses
Addiction is characterized by a progressive loss of executive control over drug-seeking and consumption, and may be associated with a behavioral shift from instrumental goal-directed actions to stimulus-response habits. Sex differences in drug addiction have been linked to changing hormone levels across the estrous cycle, and females exhibit a particular vulnerability to psychostimulants such as cocaine and amphetamines. Psychostimulants and estrogen both influence dopaminergic activity in the dorsal striatum, a region of the brain in which dopamine activity is thought to mediate the shift from action to habit. In the present set of experiments, we examined the roles of sex, …
Dose-Related Sex Differences In The Establishment Of Conditioned Disgust (Anticipatory Nausea), And The Effect Of Peripubertal And Adult Immune System Stimulation With The Endotoxin Lipopolysaccharide (Lps) On Learning And Memory In The Rat, Caylen J. Cloutier
Electronic Thesis and Dissertation Repository
This thesis examined sex differences in the establishment of lithium chloride (LiCl) – induced conditioned disgust behavior (anticipatory nausea) to a distinct context, as well as, the establishment of conditioned place avoidance (CPA) using rodent models. Also examined were potential sex differences in response to treatment with the bacterial endotoxin, lipopolysaccharide (LPS), and its effect on learning and memory. In Chapter 2, male and female naïve Long-Evans rats were injected (intraperitoneally; i.p.) with either 200 µg/kg LPS or 0.9% (NaCl), 90 minutes prior to i.p. injections of either 128 mg/kg LiCl or 0.9% NaCl, and immediately placed into a distinctive …
Directed Forgetting Of Happy And Angry Faces: The Effects Of Facial Emotion And Sex On Recognition Memory For Facial Identity, Kay Chai Tay
Directed Forgetting Of Happy And Angry Faces: The Effects Of Facial Emotion And Sex On Recognition Memory For Facial Identity, Kay Chai Tay
Dissertations and Theses Collection (Open Access)
The literature on directed forgetting – which refers to forgetting the specified information intentionally – has almost exclusively focused on either emotional words or pictures. Consequently, little is known about the impact of facial stimuli that demand more complex cognitive processing than words or pictures. A pilot study was conducted to obtain norm ratings on 152 facial images portraying neutral, happy and angry emotions. From this set of facial stimuli, 96 faces were selected for the main study. In the main study, 75 female participants were presented with 48 faces individually with equal number of happy and angry and, male …
Emotional And Behavioral Reactions To Emotional And Physical Infidelity: An Evolutionary Perspective, Alyson Kay Baker
Emotional And Behavioral Reactions To Emotional And Physical Infidelity: An Evolutionary Perspective, Alyson Kay Baker
UNLV Theses, Dissertations, Professional Papers, and Capstones
The current study examined the effect of sex on how people react, emotionally and behaviorally, to different types of partner infidelity. We expected to replicate previous findings that men experience more jealousy in reaction to their partner's sexual infidelity, and women experience more jealousy in reaction to their partners' emotional infidelity. We hypothesized that sex will affect behavioral reactions to infidelity as well. Specifically, we expected men to respond to sexual infidelity by terminating the relationship and to emotional infidelity by employing mate-guarding behaviors to prevent further infidelity. We hypothesized women would display the opposite pattern, leaving a relationship in …