Open Access. Powered by Scholars. Published by Universities.®
Experimental Analysis of Behavior Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 4 of 4
Full-Text Articles in Experimental Analysis of Behavior
Effects Of Aripiprazole Alone And In Combination With D-Amphetamine On Probability Discounting In Sprague-Dawley Rats, Paige Currie
Effects Of Aripiprazole Alone And In Combination With D-Amphetamine On Probability Discounting In Sprague-Dawley Rats, Paige Currie
Graduate Theses, Dissertations, and Problem Reports
Pharmaceuticals are helpful tools in aiding individuals with psychiatric diagnoses. Sometimes, the drug’s side effects can be more severe than the initial problem. Maladaptive behaviors, like pathological gambling, overeating, and substance abuse, are important to consider during the prescription of different pharmaceuticals, particularly those used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) and autism spectrum disorder (ASD). Individuals with these diagnoses are often prescribed: stimulants, like d-amphetamine (d-AMP; for symptoms associated with ADHD), and antipsychotics, like aripiprazole (ARI; for symptoms associated with ASD). These drugs in combination could influence maladaptive behavior, including risky choice (probability discounting). The present study …
Effects Of Acute And Chronic Nicotine Administration On Choice Of Probabilistic Outcomes, Katya A. Nolder
Effects Of Acute And Chronic Nicotine Administration On Choice Of Probabilistic Outcomes, Katya A. Nolder
Graduate Theses, Dissertations, and Problem Reports
Risky choice can be operationally defined as the choice for a larger, uncertain reinforcer over a smaller, certain reinforcer. Research suggests smokers engage in more risky or maladaptive decisions when compared to nonsmokers. The relation between nicotine and risky choice could benefit from further investigation, since nicotine is the active substance of tobacco products that maintains tobacco addiction. Acute nicotine administration has shown to alter risky choice; however, since the everyday smoker uses nicotine repeatedly, more research on chronic administration is warranted and would allow for assessment of tolerance or sensitization of these effects. The present study investigated effects of …
Chlordiazepoxide Increases Risky Choice, Devin Andrew Galdieri
Chlordiazepoxide Increases Risky Choice, Devin Andrew Galdieri
Graduate Theses, Dissertations, and Problem Reports
Probability discounting is a measure of risky choice that is correlated with maladaptive behavior and psychological disorders. Benzodiazepines are a class of drug on which relatively little risky-choice research has been conducted, particularly under conditions of chronic drug exposure. Chlordiazepoxide, a standard benzodiazepine, was administered to rats that had been trained to respond on a risky-choice task in which a choice was available between a single food pellet with 100% certainty or three food pellets with probabilities of delivery that decreased across each experimental session. During baseline, responding was sensitive to the programmed contingencies and larger-reinforcer choice decreased as the …
Probability Discounting Of Lewis And Fischer 344 Rats: Strain Comparisons At Baseline And Following Acute Administration Of D-Amphetamine, Jenny E. Ozga
Graduate Theses, Dissertations, and Problem Reports
Risky choice can be defined as choice for a larger, uncertain reinforcer over a smaller, certain reinforcer when choosing the smaller alternative maximizes reinforcement. Risky choice is studied using various procedures in the animal laboratory; one such procedure is called probability discounting. There are many variables that contribute to risky decision-making, including biological and pharmacological determinants. The present study assessed both of these variables by evaluating dose-response effects of d-amphetamine on risky choice of Lewis (LEW) and Fischer 344 (F344) rats. The probability-discounting procedure included discrete-trials choices between one food pellet delivered 100% of the time and three food …