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Experimental Analysis of Behavior Commons™
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Articles 1 - 5 of 5
Full-Text Articles in Experimental Analysis of Behavior
Development Of A Translational Model Of Co-Use Of Alcohol And Nicotine For Testing Potential Pharmacotherapies, Sarah Elizabeth Maggio
Development Of A Translational Model Of Co-Use Of Alcohol And Nicotine For Testing Potential Pharmacotherapies, Sarah Elizabeth Maggio
Theses and Dissertations--Psychology
Co-users of alcohol and nicotine are the largest group of polysubstance users worldwide. Although pharmacotherapies are available for alcohol (EtOH) or tobacco use disorders individually, it may be possible to develop a single pharmacotherapy to treat heavy drinking tobacco smokers through capitalizing on the commonalities in their mechanisms of action. Towards this goal, several models of concurrent access to EtOH and nicotine were explored as potential preclinical models of co-use using female alcohol-preferring (P) rats. Additionally, potential pharmacotherapeutics for the treatment of EtOH and nicotine co-use disorder were tested using different variations of our model. Treatments tested included (1) varenicline, …
Examining The Utility Of Behavioral Economic Demand In Addiction Science, Justin Charles Strickland
Examining The Utility Of Behavioral Economic Demand In Addiction Science, Justin Charles Strickland
Theses and Dissertations--Psychology
The marriage of perspectives from behavioral economic theory and learning theory has the potential to advance an understanding of substance use and substance use disorder. Behavioral economic demand is a central concept to this interdisciplinary approach. Evaluating demand in the laboratory and clinic can improve previous research on the relative reinforcing effects of drugs by accounting for the multi-dimensional nature of reinforcement rather than viewing reinforcement as a unitary construct. Recent advances in the commodity purchase task methodology have further simplified the measurement of demand values in human participants. This dissertation project presents a programmatic series of studies designed to …
When And Why We Protect Our Honor, Brian Michael Enjaian
When And Why We Protect Our Honor, Brian Michael Enjaian
Theses and Dissertations--Psychology
Men from a culture of honor often use physical aggression in response to threats as a way of restoring lost honor. Threats can range from being called an offensive name to someone flirting with their romantic partner. On the other hand, women from a culture of honor are expected to be submissive and avoid situations that can result in harm to their reputation. However, a recent meta-analytic review of the literature suggests that women do not always avoid situations that can harm their reputation. Rather, women in a culture of honor also use physical aggression in response to threats. In …
Neurobehavioral Measurements Of Natural And Opioid Reward Value, Aaron Paul Smith
Neurobehavioral Measurements Of Natural And Opioid Reward Value, Aaron Paul Smith
Theses and Dissertations--Psychology
In the last decade, (non)prescription opioid abuse, opioid use disorder (OUD) diagnoses, and opioid-related overdoses have risen and represent a significant public health concern. One method of understanding OUD is as a disorder of choice that requires choosing opioid rewards at the expense of other nondrug rewards. The characterization of OUD as a disorder of choice is important as it implicates decision- making processes as therapeutic targets, such as the valuation of opioid rewards. However, reward-value measurement and interpretation are traditionally different in substance abuse research compared to related fields such as economics, animal behavior, and neuroeconomics and may be …
Measuring Glutamate And Oxygen In Brain Reward Circuits In Animal Models Of Cocaine Abuse And Decision-Making, Seth Richard Batten
Measuring Glutamate And Oxygen In Brain Reward Circuits In Animal Models Of Cocaine Abuse And Decision-Making, Seth Richard Batten
Theses and Dissertations--Psychology
Drug-specific reward and associated effects on neural signaling are often studied between subjects, where one group self-administers drug and a separate group self-administers a natural reinforcer. However, exposure to drugs of abuse can cause long-term neural adaptations that can affect how an organism responds to drug reward, natural reward, and their reward-associated stimuli. Thus, to isolate drug-specific effects it is important to use models that expose the same organism to all of the aforementioned. Multiple schedules provide a means of dissociating the rewarding effects of a drug from the rewarding effects of food within a single animal. Further, drug users …