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Biological Psychology

Theses/Dissertations

Adolescence

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Full-Text Articles in Experimental Analysis of Behavior

Cannabinoid-Induced Behavioral Sensitization In Adolescent Sprague-Dawley Rats, Michelle Stone Oct 2018

Cannabinoid-Induced Behavioral Sensitization In Adolescent Sprague-Dawley Rats, Michelle Stone

Electronic Theses, Projects, and Dissertations

Adolescent cannabis use has grown because of increased availability and higher societal acceptance. This increase in cannabis use is problematic as adolescents who experiment with cannabis are more likely to abuse cannabis and experiment with other illicit drugs such as cocaine. The reason for the greater susceptibility to drugs use is unclear and may be the result of altered drug sensitivity after cannabis exposure. Thus, the present investigation used the behavioral sensitization paradigm to examine the behavioral response of early adolescent rats to the cannabinoid agonist CP 55,940 (CP) or cocaine after repeated cannabinoid administration. It was hypothesized that: (1) …

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Effects Of Social Interaction On Morphine Conditioned Place Preference In Adolescent Male Rats, Virginia G. Weiss Jan 2018

Effects Of Social Interaction On Morphine Conditioned Place Preference In Adolescent Male Rats, Virginia G. Weiss

Theses and Dissertations--Psychology

The fact that adolescents commonly initiate drug use in social settings is well established. Both clinical and preclinical research has investigated how social interaction is altered by a variety of drugs of abuse. What is less understood is how the rewarding value of drugs of abuse is affected by the presence of social peers. This dissertation aimed to investigate the interaction of morphine and social play on conditioned place preference (CPP) in adolescent male Sprague Dawley rats, using both behavioral and immunohistochemistry (IHC) methods. Rats were exposed to morphine (0, 1, or 3 mg/kg; s.c.), social interaction, or a combination …

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